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Author: Claude G. Wasterlain Publisher: MIT Press ISBN: 0262232456 Category : Medical Languages : en Pages : 653
Book Description
A comprehensive review of recent advances in the most severe form of epilepsy, focusing on two areas in which progress has been most rapid: basic mechanisms and treatment. Interest in status epilepticus--the most extreme form of epilepsy, involving continuous seizures--has surged in the last 20 years. Since 1979 there have been over 4,000 publications on the subject, including more than 1,700 in the last five years. No other text provides such a comprehensive review of the recent advances in the field of status epilepticus. The book focuses on the two areas in which progress has been most rapid: basic mechanisms and treatment. There is now a greater understanding of the mechanisms and complications of status epilepticus at the molecular level, which should eventually lead to improved therapy, and treatment strategies today have a greater sense of urgency because of the realization that neuronal apoptosis and necrosis can be triggered very quickly. After an overview of history, classification, and epidemiology, the contributors consider clinical phenomenology, biological markers, pathophysiology, brain damage, epileptogenesis, therapeutic principles, pharmacology, and therapeutic management. Their contributions are equally divided between studies of basic mechanisms in animal models and clinical studies, so that the reader can turn easily from the reductionist experiment that isolates a small component of status to the complex clinical situation in which these principles can translate into therapeutic action. The goal is to provide a scientific rationale for clinical decisions while developing therapeutic attitudes that are firmly grounded in pathophysiology.
Author: Claude G. Wasterlain Publisher: MIT Press ISBN: 0262232456 Category : Medical Languages : en Pages : 653
Book Description
A comprehensive review of recent advances in the most severe form of epilepsy, focusing on two areas in which progress has been most rapid: basic mechanisms and treatment. Interest in status epilepticus--the most extreme form of epilepsy, involving continuous seizures--has surged in the last 20 years. Since 1979 there have been over 4,000 publications on the subject, including more than 1,700 in the last five years. No other text provides such a comprehensive review of the recent advances in the field of status epilepticus. The book focuses on the two areas in which progress has been most rapid: basic mechanisms and treatment. There is now a greater understanding of the mechanisms and complications of status epilepticus at the molecular level, which should eventually lead to improved therapy, and treatment strategies today have a greater sense of urgency because of the realization that neuronal apoptosis and necrosis can be triggered very quickly. After an overview of history, classification, and epidemiology, the contributors consider clinical phenomenology, biological markers, pathophysiology, brain damage, epileptogenesis, therapeutic principles, pharmacology, and therapeutic management. Their contributions are equally divided between studies of basic mechanisms in animal models and clinical studies, so that the reader can turn easily from the reductionist experiment that isolates a small component of status to the complex clinical situation in which these principles can translate into therapeutic action. The goal is to provide a scientific rationale for clinical decisions while developing therapeutic attitudes that are firmly grounded in pathophysiology.
Author: Eva Morava Publisher: Springer ISBN: 366254119X Category : Medical Languages : en Pages : 110
Book Description
JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
Author: Isabelle Jambaqué Publisher: Springer Science & Business Media ISBN: 0306476126 Category : Medical Languages : en Pages : 296
Book Description
This book is devoted to the neuropsychological description of childhood epilepsy, a neurolo- cal condition that constitutes one of the most prevalent forms of chronic and disabling childhood illnesses. Indeed, one child out of 20 experiences one or more seizures before the age of 5, and one in a hundred develops epilepsy as a chronic disorder. Approximately half of these children with epilepsy display academic difficulties and/or behavioral disorders. Moreoever, it is now believed that a sizable proportion of children with learning disability suffer from undiagnosed epilepsy. While a great number of textbooks have been devoted to various medical aspects of chi- hood epilepsy (diagnosis, genetics, etiology, drug and surgical treatment, etc.), there have been no comprehensive accounts of the cognitive consequences of this condition. Advance of medical knowledge has shown that childhood epilepsy should not be considered as a single disorder but encompasses a whole range of different conditions that exhibit specific clinical EEG and outcome characteristics. It is not becoming apparent that these various clinical entities have different cognitive expression that yet need to be specified. The purpose of this book is to provide a complete up-to-date analysis of this multi-faceted pathology.
Author: LENOBLE Evelyne Publisher: Lavoisier ISBN: 225770584X Category : Learning disabilities Languages : en Pages : 206
Book Description
Les chemins qu’empruntent les enfants pour apprendre gardent toujours une part de mystère et réservent nombre de surprises, le plus souvent fort agréables. Lorsque des embûches se présentent, lorsque l’enfant peine pour apprendre, les parents, l’entourage familial ou éducatif au sens large ainsi que les enseignants, sont bien souvent pris au dépourvu. L’appel aux professionnels de santé est devenu un recours incontournable, dès que des « difficultés d’apprentissage » sont repérées chez un enfant. Écouter, observer... pour pouvoir aider au mieux, voici le défi auquel sont confrontés les soignants en collaboration avec la famille et l’équipe enseignante. Les auteurs de cet ouvrage – pédopsychiatres, psychologues, orthophonistes – s’appuient sur une longue expérience clinique de consultation hospitalière spécialisée dédiée aux troubles du langage et des apprentissages chez l’enfant (centre référent). L’enjeu d’un bilan pluridisciplinaire réalisé dans ce cadre est de proposer une analyse approfondie des difficultés, et de dégager, à partir des observations recueillies, des points d’appui et des leviers afin d’orienter les actions thérapeutiques et les remédiations dont pourra bénéficier l’enfant en difficulté. Les nombreuses vignettes cliniques décrivant le parcours des enfants au sein de ce centre référent ainsi que la description des outils de travail clinique utilisés, feront partager au lecteur l’expérience quotidienne de l’équipe d’auteurs cliniciens. Largement illustré par des cas cliniques évocateurs, ce livre intéressera tous les acteurs du soin – équipes de proximité (CMP, CMPP, SESSAD... ), équipes hospitalières spécialisées et praticiens libéraux (orthophonistes, psychologues, psychomotriciens, ergothérapeutes, psychopédagogues, pédiatres, pédopsychiatres, neuropédiatres...) – ainsi que les acteurs des champs pédagogique, éducatif et associatif, engagés auprès des enfants, sans oublier les familles.
Author: Alain Malafosse Publisher: John Libbey Eurotext ISBN: 9780861964369 Category : Medical Languages : en Pages : 568
Book Description
Idiopathic generalised epilepsies are characterised by strong genetic factors and multiple clinical phenotypes; animal models of untreated epilepsies are relevant to some of the clinical syndromes found in humans. This volume is the first to confront human clinical, animal (experimental) as well as basic and applied genetic data. Main section headings: Current approaches; Familial neonatal and infantile convulsions; Absence seizures and absence epilepsy; Juvenile myoclonic epilepsy and related syndromes; Photosensitivity; Pathophysiology of convulsive seizures; Fundamental and therapeutic aspects.
Author: Alexis Arzimanoglou Publisher: John Libbey Eurotext ISBN: 9782742001118 Category : Medical Languages : en Pages : 264
Book Description
Jean Aicardi Days, October 1995. These scientific days were organised in tribute to Jean Aicardi, the internationally recognised neuropaediatrician. His friends and colleagues, eminent specialists from all over the world, exchanged their experiences and latest data on infantile epilepsy, with particular emphasis on aspects including migraine and epilepsy, the environmental determinants of cerebral development and cognitive disorders.
Author: Antonio V. Delgado-Escueta Publisher: Lippincott Williams & Wilkins ISBN: 9780781752480 Category : Medical Languages : en Pages : 368
Book Description
This volume is the first comprehensive text and clinical reference on idiopathic myoclonic epilepsies of infancy, childhood, adolescence, and adulthood. The world’s foremost experts describe the phenotypes and subtypes of myoclonic epilepsies and the underlying molecular defects and summarize cutting-edge advances in molecular genetics that shed new light on the etiologies of these syndromes. The book offers clinicians much-needed assistance in recognizing and diagnosing idiopathic myoclonic epilepsies and selecting appropriate treatment. Each chapter includes diagnostic and treatment algorithms to guide practitioners in clinical decision making.
Author: Harald Tschesche Publisher: Walter de Gruyter GmbH & Co KG ISBN: 311239304X Category : Science Languages : en Pages : 448
Book Description
No detailed description available for "Review Articles, including those from an International Conference held in Bielefeld, F. R. of Germany, June 1-2, 1984".
Author: Jerome Engel Publisher: Lippincott Williams & Wilkins ISBN: 9780781757775 Category : Medical Languages : en Pages : 1272
Book Description
Written and edited by world-renowned authorities, this three-volume work is, to quote a reviewer, "the definitive textbook about seizures and epilepsy". This Second Edition is thoroughly updated and gives you a complete print and multimedia package: the three-volume set plus access to an integrated content Website. More than 300 chapters cover the spectrum of biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Included are detailed discussions of seizure types and epilepsy syndromes; relationships between physiology and clinical events; psychiatric and medical comorbidity; conditions that could be mistaken for epilepsy; and an increasing range of pharmacologic, surgical, and alternative therapies, including vagus nerve stimulation and deep brain stimulation. This edition describes many new antiepileptic drugs, major advances in surgical treatment, and state-of-the-art neuroimaging, EEG, and other technologies for diagnosis and seizure prediction. A companion Website offers instant access to the complete, fully searchable text, plus an image bank of additional figures, video footage, and annual updates to selected chapters.
Author: Claude G. Wasterlain
Author: Claude G. Wasterlain
Author: Eva Morava
Author: Isabelle Jambaqué
Author: LENOBLE Evelyne
Author: Alain Malafosse
Author: Alexis Arzimanoglou
Author: Antonio V. Delgado-Escueta
Author: Joseph Roger
Author: Harald Tschesche
Author: Jerome Engel