Molecular Biology of the Cell PDF Download

Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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Author: J. Richard McIntosh
Publisher: Garland Science
ISBN: 0429576269
Category : Medical
Languages : en
Pages : 995

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Book Description
Understanding Cancer is a brand new undergraduate textbook for students without prior training in biology that integrates an introduction to cancer medicine with descriptions of the biological processes that go wrong to cause cancer’s onset and progression. It also highlights the human side of cancer with stories of patients and loved ones touched by the disease, dealing with diagnosis, treatment, and the prospect of death as well as the broader societal aspects of cancer and its prevention. Key discoveries that have improved our understanding of cancer are presented in sidebars. In spite of this diversity, the book maintains precision and simplicity in describing what is and is not known about cancer, describing the strengths and limitations of current treatments

Author: Arthur B. Pardee
Publisher: John Wiley & Sons
ISBN: 1118208455
Category : Medical
Languages : en
Pages : 404

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Book Description
Offers a broad audience a concise presentation of the most up-to-date knowledge about the biology and treatment of cancer Full coverage of cancer prevention and control Clear, thorough discussion of current and possible future therapies Edited by two of the most eminent and widely recognized scholars of cancer research and therapeutics in the world, with contributions from top researchers and clinicians from across North America

Author: Irina Kareva
Publisher: Academic Press
ISBN: 012813674X
Category : Medical
Languages : en
Pages : 120

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Book Description
Understanding Cancer from a Systems Biology Point of View: From Observation to Theory and Back starts with a basic question, why do we sometimes observe accelerated metastatic growth after resection of primary tumors? Next, it helps readers understand the systemic nature of cancer and how it affects treatment approaches and decisions. The book puts together aspects of cancer that many readers have most likely never combined, using unfamiliar, novel methods. It is a valuable resource for cancer researchers, cancer biologists, mathematicians and members of the biomedical field who are interested in applying systems biology methodologies for understanding and treating cancer. - Explains the systemic nature of cancer and how it affects decisions on treatment - Brings a variety of methods together, showing, in detail, the logical approach to finding answers to complex questions - Discusses the theoretical underpinnings of cancer as a systemic disease, providing the reader with valuable information on applicable cases

Author: John Mendelsohn
Publisher: Elsevier Health Sciences
ISBN: 1437710999
Category : Medical
Languages : en
Pages : 1948

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Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of cancer. A team of leading experts thoroughly explain the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating cutting-edge advances and the newest research, the book provides thorough descriptions of everything from molecular abnormalities in common cancers to new approaches for cancer therapy. Features sweeping updates throughout, including molecular targets for the development of anti-cancer drugs, gene therapy, and vaccines...keeping you on the cutting edge of your specialty. Offers a new, more user-friendly full-color format so the information that you need is easier to find. Presents abundant figures-all redrawn in full color-illustrating major concepts for easier comprehension. Features numerous descriptions of the latest clinical strategies-helping you to understand and take advantage of today’s state-of-the-art biotechnology advances.

Author: Francesco Pezzella
Publisher: Oxford University Press
ISBN: 0198779453
Category : Medical
Languages : en
Pages : 505

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Book Description
The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.

Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241547111
Category : Business & Economics
Languages : en
Pages : 57

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Book Description
In 2005, 7.6 million people died of cancer. More than 70% of those deaths occured in low and middle income countries. WHO has developed a series of six modules that provides practical advice for programme managers and policy-makers on how to advocate, plan and implement effective cancer control programmes, particularly in low and middle income countries.The WHO guide is a response to the World Health Assembly resolution on cancer prevention and control (WHA58.22), adopted in May 2005, which calls on Member States to intensify action against cancer by developing and reinforcing cancer control programmes.

Author: Wellington Pinheiro dos
Publisher:
ISBN: 9781536175202
Category : Cancer
Languages : en
Pages : 174

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Book Description
Diagnosis can be a deep investigative process, complex by nature. The diagnostic processes have become much more multidisciplinary, demanding the use of an eclectic set of technological methodologies and tools, especially from the Fourth Revolution. Biosensors, Artificial Intelligence, Internet of Things and 3D Printing have become common terms in health research. Cancer in all its forms has become one of the biggest public health issues of the twentieth century. Among all types of cancer, breast cancer is the most dangerous for older and middle-aged women; it is also the most common form of cancer among the female population. Breast cancer is among the five most common cancers worldwide. This disease has been proliferating in developed, underdeveloped and developing countries. Its incidence rate is increasing with the average life expectancy of the population and with the adoption of new forms of consumption. There are some preventive strategies for breast cancer, such as stimulating visual inspection and touching of the breasts. However, they are not efficient enough to impact breast cancer mortality rate because the disease is still being diagnosed late in many cases. Therefore, a deeper understanding of the disease is necessary, including its risk factors and strategies for early identification and efficient treatment. The existence of these tools in public healthcare systems is important because they may contribute to increasing the chances of cure and the treatment options, decreasing mortality rates. Herein this collection book, we present to readers a set of works from the state-of-the-art dealing with cancer diagnosis using biosensors, artificial intelligence and other approaches. We hope this collection could present some of the state of the art of innovative techniques based on the Fourth Industrial Revolution to support early and accurate diagnosis of cancer, especially breast cancer.

Author: Stanton L. Gerson
Publisher: Elsevier
ISBN: 0080491367
Category : Science
Languages : en
Pages : 555

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Book Description
The Second Edition of Gene Therapy of Cancer provides crucial updates on the basic science and ongoing research in this field, examining the state of the art technology in gene therapy and its therapeutic applications to the treatment of cancer. The clinical chapters are improved to include new areas of research and more successful trials. Chapters emphasize the scientific basis of gene therapy using immune, oncogene, antisense, pro-drug activating, and drug resistance gene targets, while other chapters discuss therapeutic approaches and clinical applications. This book is a valuable reference for anyone needing to stay abreast of the latest advances in gene therapy treatment for cancer. - Provides in-depth description of targeted systems and treatment strategies - Explains the underlying cancer biology necessary for understanding a given therapeutic approach - Extensively covers immune therapeutics of vaccines, cytokines, and peptide-induced responses - Presents translational focus with emphasis on requirements for clinical implementation - Incorporates detailed illustrations of vectors and therapeutic approaches ideal for classroom presentations and general reference

Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
ISBN: 1439170916
Category : Health & Fitness
Languages : en
Pages : 624

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Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.