The Analysis of Regulatory DNA: Current Developments, Knowledge and Applications Uncovering Gene Regulation

The Analysis of Regulatory DNA: Current Developments, Knowledge and Applications Uncovering Gene Regulation PDF Author: Kenneth Berendzen
Publisher: Bentham Science Publishers
ISBN: 1608054926
Category : Science
Languages : en
Pages : 225

Book Description
A major goal of integrative research is understanding regulatory networks to such an extent as to allow researchers to model developmental and stress responses. Regulatory networks of living systems include complex and vast interactions between proteins, metabolites, RNA, various signaling molecules and DNA. One aspect of systems biology is understanding the dynamics of protein-DNA interactions affecting gene expression that are caused by transcription factors (TFs) and chromatin remodeling factors. This e-book provides a resource for summarizing current knowledge eukaryotic transcription and explores cis-elements and methods for their analysis, prediction and discovery. The book also presents an overview of exploring gene regulatory networks, chromatin, and miRNAs. Information about state-of-the-art techniques for the determination of TF - cis-element interactions in vivo and in silico give cutting edge insights on how genomic-scale research is being approached. The Analysis of Regulatory DNA provides readers with both the necessary background knowledge and provocative, up-to-date insights aimed at sparking new and vibrant experimental designs for understanding and predicting cis-elements in the eukaryotic genome.

Alabama Quilts

Alabama Quilts PDF Author: Mary Elizabeth Johnson Huff
Publisher: Univ. Press of Mississippi
ISBN: 1496831438
Category : Crafts & Hobbies
Languages : en
Pages : 248

Book Description
Winner of the 2022 James F. Sulzby Book Award from the Alabama Historical Association Alabama Quilts: Wilderness through World War II, 1682–1950 is a look at the quilts of the state from before Alabama was part of the Mississippi Territory through the Second World War—a period of 268 years. The quilts are examined for their cultural context—that is, within the community and time in which they were made, the lives of the makers, and the events for which they were made. Starting as far back as 1682, with a fragment that research indicates could possibly be the oldest quilt in America, the volume covers quilting in Alabama up through 1950. There are seven sections in the book to represent each time period of quilting in Alabama, and each section discusses the particular factors that influenced the appearance of the quilts, such as migration and population patterns, socioeconomic conditions, political climate, lifestyle paradigms, and historic events. Interwoven in this narrative are the stories of individuals associated with certain quilts, as recorded on quilt documentation forms. The book also includes over 265 beautiful photographs of the quilts and their intricate details. To make this book possible, authors Mary Elizabeth Johnson Huff and Carole Ann King worked with libraries, historic homes, museums, and quilt guilds around the state of Alabama, spending days on formal quilt documentation, while also holding lectures across the state and informal “quilt sharings.” The efforts of the authors involved so many community people—from historians, preservationists, librarians, textile historians, local historians, museum curators, and genealogists to quilt guild members, quilt shop owners, and quilt owners—making Alabama Quilts not only a celebration of the quilting culture within the state but also the many enthusiasts who have played a role in creating and sustaining this important art.

Uncovering the Territorial Dimension of European Union Cohesion Policy

Uncovering the Territorial Dimension of European Union Cohesion Policy PDF Author: Eduardo Medeiros
Publisher: Routledge
ISBN: 1351689827
Category : Political Science
Languages : en
Pages : 239

Book Description
Despite the non-territorialised strategic goals of the EU 2020 Strategy, the long-term aim of EU Cohesion Policy to promote harmonious development of the European territory – social, economic, and ‘territorial cohesion’ – remains a central goal of achieving a more cohesive EU territory. This book examines the ‘territorial dimension’ of EU Cohesion Policy, specifically assessing territorial impacts at the various spatial levels, engaging theoretically and empirically with the notion and role of the ‘territorial dimension’ within a strongly fragmented EU policymaking process, and examining more generally EU Cohesion Policy, as the main driver of the EU territorial development process. It provides an updated and fresh theoretical discussion on the precise meaning of the ‘territorial dimension’ of policies and the relatively recent EU policy evaluation technique, known as ‘Territorial Impact Assessment’ (TIA). Assessing the history, relevance, efficiency and effectiveness of these procedures, it presents several empirical findings on the implementation of specific territorial-focus and place-based financial instruments, as part of the Territorial Agendas and the EU goal of achieving a more integrated, territorial approach. This text will be of key interest to scholars, students and practitioners of spatial planning and cohesion policy, European sector policies and European spatial planning, and more broadly to European and EU studies/politics, regional economic geography and public policy.

Cases on Uncovering Corporate Governance Challenges in Asian Markets

Cases on Uncovering Corporate Governance Challenges in Asian Markets PDF Author: Hasan, Rashedul
Publisher: IGI Global
ISBN: 1668498693
Category : Business & Economics
Languages : en
Pages : 276

Book Description
Corporate governance challenges in Asian markets have led to high-profile scandals and negative consequences for stakeholders, driven by weak governance structures, transparency deficiencies, and insufficient accountability. These issues are compounded by cultural and societal influences, emphasizing the need for a comprehensive understanding of the underlying factors at play. Cases on Uncovering Corporate Governance Challenges in Asian Markets, offers a compelling solution to address these pressing issues. Through a thorough analysis of prominent corporate scandals in Asia, the book investigates their origins, effects, and cultural influences that have contributed to their escalation. By scrutinizing these cases, the book provides actionable recommendations to enhance corporate governance practices, promoting transparency, accountability, and ethical conduct within companies. It serves as an indispensable resource for academic scholars, researchers, practitioners, policymakers, and students seeking insights into corporate governance in Asia. With its comprehensive understanding of governance failures and practical recommendations, Cases on Uncovering Corporate Governance Challenges in Asian Markets catalyzes positive change in the business landscape of Asian markets.

From free trade to globalization uncovering the mist of 21st century

From free trade to globalization uncovering the mist of 21st century PDF Author: José Alberto, Pérez Toro
Publisher: Editorial Tadeo Lozano
ISBN: 9587251849
Category : Business & Economics
Languages : en
Pages : 584

Book Description
Much has been written about globalization as an economic and political concept. The academic debate looks forward for explanations about the historical roots and development of this emerging phenomenon where the Nation-State’s evolved into a system where nations are ruled by the dynamics of global interdependence. Globalization in the new era is characterized as a process where geographical, political and cultural borders tend to dissolve. The Westphalia notion of sovereignty capitulates against the principle of political subordination as integration of local power ensuring national legitimacy.

Uncovering Spiritual Narratives

Uncovering Spiritual Narratives PDF Author: Suzanne M. Coyle
Publisher: Fortress Press
ISBN: 1451438680
Category : Religion
Languages : en
Pages : 167

Book Description
All cultures use story as a way to make sense of life experiences. Yet for many, particularly in the western world, only a single story line is seen as the “real truth.” Using narrative therapy as a caregiving approach can help individuals uncover multilayered narratives that are far more complex and liberating. Coyle contends that not only are these more complex narratives more helpful in giving our lives meaning, they also critique the cultural discourses in which they arose. Drawing on both theological approaches and real life experiences, Coyle creates a contextual pastoral theology that helps caregivers find the power of God in people’s stories.

Uncovering the Logic of English: A Common-Sense Solution to America's Literacy Crisis

Uncovering the Logic of English: A Common-Sense Solution to America's Literacy Crisis PDF Author: Denise Eide
Publisher: Logic of English, Inc
ISBN: 1936706075
Category : Education
Languages : en
Pages : 204

Book Description
"English is so illogical!" It is generally believed that English is a language of exceptions. For many, learning to spell and read is frustrating. For some, it is impossible... especially for the 29% of Americans who are functionally illiterate. But what if the problem is not the language itself, but the rules we were taught? What if we could see the complexity of English as a powerful tool rather than a hindrance? --Denise Eide Uncovering the Logic of English challenges the notion that English is illogical by systematically explaining English spelling and answering questions like "Why is there a silent final E in have, large, and house?" and "Why is discussion spelled with -sion rather than -tion?" With easy-to-read examples and anecdotes, this book describes: - the phonograms and spelling rules which explain 98% of English words - how English words are formed and how this knowledge can revolutionize vocabulary development - how understanding the reasons behind English spelling prevents students from needing to guess The author's inspiring commentary makes a compelling case that understanding the logic of English could transform literacy education and help solve America's literacy crisis. Thorough and filled with the latest linguistic and reading research, Uncovering the Logic of English demonstrates why this systematic approach should be as foundational to our education as 1+1=2.

Uncoverings 2011

Uncoverings 2011 PDF Author: American Quilt Study Group
Publisher:
ISBN: 9781877859274
Category :
Languages : en
Pages : 0

Book Description


Uncovering Sin

Uncovering Sin PDF Author: Rosy Fairhurst
Publisher: SPCK
ISBN: 0281068801
Category : Religion
Languages : en
Pages : 72

Book Description
This approachable Lent course invites us to view sin as something to be understood, rather than condemned. It argues that our darker traits must be coaxed into the light in order to manage them and work towards healing and renewal. An intriguing choice for both personal and group reflection.

Uncovering Race

Uncovering Race PDF Author: Amy Alexander
Publisher: Beacon Press
ISBN: 0807061026
Category : Biography & Autobiography
Languages : en
Pages : 241

Book Description
From an award-winning black journalist, a tough-minded look at the treatment of ethnic minorities both in newsrooms and in the reporting that comes out of them, within the changing media landscape. From the Rodney King riots to the racial inequities of the new digital media, Amy Alexander has chronicled the biggest race and class stories of the modern era in American journalism. Beginning in the bare-knuckled newsrooms of 1980s San Francisco, her career spans a period of industry-wide economic collapse and tremendous national demographic changes. Despite reporting in some of the country’s most diverse cities, including San Francisco, Boston, and Miami, Alexander consistently encountered a stubbornly white, male press corps and a surprising lack of news concerning the ethnic communities in these multicultural metropolises. Driven to shed light on the race and class struggles taking place in the United States, Alexander embarked on a rollercoaster career marked by cultural conflicts within newsrooms. Along the way, her identity as a black woman journalist changed dramatically, an evolution that coincided with sweeping changes in the media industry and the advent of the Internet. Armed with census data and news-industry demographic research, Alexander explains how the so-called New Media is reenacting Old Media’s biases. She argues that the idea of newsroom diversity—at best an afterthought in good economic times—has all but fallen off the table as the industry fights for its economic life, a dynamic that will ultimately speed the demise of venerable news outlets. Moreover, for the shrinking number of journalists of color who currently work at big news organizations, the lingering ethos of having to be “twice as good” as their white counterparts continues; it is a reality that threatens to stifle another generation of practitioners from “non-traditional” backgrounds. In this hard-hitting account, Alexander evaluates her own career in the context of the continually evolving story of America’s growing ethnic populations and the homogenous newsrooms producing our nation’s too often monochromatic coverage. This veteran journalist examines the major news stories that were entrenched in the great race debate of the past three decades, stories like those of Elián González, Janet Cooke, Jayson Blair, Tavis Smiley, the tragedy of Hurricane Katrina, and the election of Barack Obama. Uncovering Race offers sharp analysis of how race, gender, and class come to bear on newsrooms, and takes aim at mainstream media’s failure to successfully cover a browner, younger nation—a failure that Alexander argues is speeding news organizations’ demise faster than the Internet.