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Author: Dinesh Singh Thakur Publisher: Simon and Schuster ISBN: 9392099223 Category : Law Languages : en Pages : 498
Book Description
Since 2004, when the fraud at Ranbaxy, the largest Indian pharmaceutical company at the time first came to light, the Indian pharmaceutical industry and clinical research organizations have been rocked by a series of scandals after investigations by American and European drug regulators. While the West has responded to concerns about quality of “Made in India” medicine by blocking exports from many Indian pharmaceutical companies, the Indian government responded not with regulatory reform but conspiracy theories about “vested interests” working against India. More worryingly, the Indian state has also turned a blind eye to a far more serious quality crisis in its domestic pharmaceutical market. At times, these quality issues manifest themselves in the deaths of Indian citizens as happened in early 2020 when 11 children died in Jammu because of adulterated cough syrup. On other occasions, a dodgy drug approval process has led to the Indian regulator approving sales of drugs that have never been approved by regulators in the developed markets. The result is not just poor health outcomes but outsize profits for pharmaceutical companies manufacturing medicines that have never been validated through scientifically rigorous clinical trials for therapeutic evidence. These twin crises, in both the domestic and export markets, is because India has either outdated regulations or no regulations in some areas. Even the outdated regulations are enforced with kids gloves by drug inspectors and judicial magistrates who are ready to forgive even those whose drugs are found to contain barely any active ingredient or dangerously high levels of bacterial endotoxins. In a race for growth of the pharmaceutical industry, the Indian state has sacrificed scientific rigour and ignored the basic principles of public health. Given India’s position as the pharmacy of the developing world, the failure of the Indian state is a problem for not just India but most of the developing world. This timely, important and compelling book based on deep research, questions and analyzes the actions of the institutions that are responsible for the safety and efficacy of the Indian drug supply in the context of the historical evolution of the Drugs Act 1940 from pre-Independence India to the present day. The future of Indian public health lies in responding to the issues raised in this book.
Author: Dinesh Singh Thakur Publisher: Simon and Schuster ISBN: 9392099223 Category : Law Languages : en Pages : 498
Book Description
Since 2004, when the fraud at Ranbaxy, the largest Indian pharmaceutical company at the time first came to light, the Indian pharmaceutical industry and clinical research organizations have been rocked by a series of scandals after investigations by American and European drug regulators. While the West has responded to concerns about quality of “Made in India” medicine by blocking exports from many Indian pharmaceutical companies, the Indian government responded not with regulatory reform but conspiracy theories about “vested interests” working against India. More worryingly, the Indian state has also turned a blind eye to a far more serious quality crisis in its domestic pharmaceutical market. At times, these quality issues manifest themselves in the deaths of Indian citizens as happened in early 2020 when 11 children died in Jammu because of adulterated cough syrup. On other occasions, a dodgy drug approval process has led to the Indian regulator approving sales of drugs that have never been approved by regulators in the developed markets. The result is not just poor health outcomes but outsize profits for pharmaceutical companies manufacturing medicines that have never been validated through scientifically rigorous clinical trials for therapeutic evidence. These twin crises, in both the domestic and export markets, is because India has either outdated regulations or no regulations in some areas. Even the outdated regulations are enforced with kids gloves by drug inspectors and judicial magistrates who are ready to forgive even those whose drugs are found to contain barely any active ingredient or dangerously high levels of bacterial endotoxins. In a race for growth of the pharmaceutical industry, the Indian state has sacrificed scientific rigour and ignored the basic principles of public health. Given India’s position as the pharmacy of the developing world, the failure of the Indian state is a problem for not just India but most of the developing world. This timely, important and compelling book based on deep research, questions and analyzes the actions of the institutions that are responsible for the safety and efficacy of the Indian drug supply in the context of the historical evolution of the Drugs Act 1940 from pre-Independence India to the present day. The future of Indian public health lies in responding to the issues raised in this book.
Author: Merrill Goozner Publisher: Univ of California Press ISBN: 9780520246706 Category : Medical Languages : en Pages : 308
Book Description
"Goozner shows how drug innovation is driven by dedicated scientists intent on finding cures for diseases, not by pharmaceutical firms, whose bottom line often takes precedence over the advance of medicine. Stories of a university biochemist who spent twenty years searching for single blood protein that later became the best-selling biotech drug in the world, a government employee who discovered the causes for dozens of crippling genetic disorders, and the Department of Energy-funded research that made the Human Genome Project possible - these accounts illustrate how medical breakthroughs actually take place.".
Author: Shannon Branch Publisher: ISBN: 9780985511913 Category : Languages : en Pages : 108
Book Description
"THE TRUTH IS THE HARDEST PILL TO SWALLOW" is a brutally honest, truthful, and accurate guide to relationships, marriages, dating, and sex from the perspective of a single black male who has experienced a lot as well as witnessed much from life. NO sugar coating, NO fairy tales, NO feminist or sexist nonsense. Just telling it how it is. The way it should be told.
Author: Katinka Newman Publisher: Kings Road Publishing ISBN: 1786062259 Category : Medical Languages : en Pages : 296
Book Description
While going through a divorce, documentary filmmaker Katinka Blackford Newman took an antidepressant. Not unusual – except that things didn't turn out quite as she expected. She went into a four-day toxic psychosis with violent hallucinations, imagining she had killed her children, and in fact attacking herself with a knife. Caught up in a real-life nightmare when doctors didn't realise she was suffering side effects of more pills, she went into a year-long decline. Soon she was wandering around in an old dressing gown, unable to care for herself, and dribbling. She nearly lost everything, but luck stepped in; treated at another hospital, she was taken off all the medication and made a miraculous recovery within weeks. By publicising her story, Katinka went on to make some startling discoveries. Could there really be thousands around the world who kill themselves and others from these drugs? What of the billions of dollars in settlements paid out by drug companies? Could they really be the cause of world mass killings, such as the Germanwings pilot who took an airliner down, killing 150, while on exactly the same medication as the author when she became psychotic? And how come so many people are taking these drugs when experts say they are no more effective than a sugarcoated pill for people like her, who are distressed rather than depressed? Moving, frightening and at times funny, this is the story of how a single mum in Harlesden, North-West London, juggles life and her quest for love in order to investigate Big Pharma. For more information visit www.thepillthatsteals.com
Author: Paul Ballman Publisher: ISBN: 9781911079002 Category : Business & Economics Languages : en Pages : 278
Book Description
Paul Ballman has helped some of the biggest companies in the world get their leadership strategies on track. He has conducted detailed interviews with 2,000 leaders about what has worked for them and why. He has studied the simple success formulas and models that are peddled by gurus across the industry, and come to the conclusion that in the real world they just don't work. He now invites you to take the Red Pill and discover the truth about leadership. Why are the existing formulas for success continually found wanting? How can you tell a fad from enduring wisdom? What are the causes of the most spectacular leadership failures? And, most importantly, what can you do about it? Entertaining, insightful and practical. RED PILL lets you become your own guru.
Author: Tom Nesi Publisher: Macmillan ISBN: 142993185X Category : Business & Economics Languages : en Pages : 317
Book Description
To the millions of Americans who suffer from chronic pain and arthritis, Vioxx seemed like a miracle. One of the most widely promoted and prescribed pain medications in the world -- used by more than twenty million people -- it was endorsed by the medical establishment and celebrities such as Olympic champion figure skater Dorothy Hamill. With annual sales of $2.5 billion, Vioxx became a pharmaceutical bonanza before being abruptly taken off the market in September 2004, after it was revealed that it led to an increased risk of heart-related disease and death. Drawing on internal documents, video footage, court testimony, and exclusive interviews, as well as three decades of experience inside the medical industry, Tom Nesi tells the dramatic story of what the drug's manufacturer, Merck, knew and when. It is a compelling narrative of business and medical science run amok, with a cast of characters ranging from those at the highest levels of the multibillion-dollar pharmaceutical industry to research scientists, marketers, and drug company sales reps. Here also are accounts from physicians, lawyers, financial analysts, and patients and their families whose lives have been forever altered by Vioxx. Set against a fascinating history of the origins of the modern pharmaceutical industry, POISON PILLS is a shocking tale that involves the breakdown of the United States medical system, the failures of the Food and Drug Administration, and enormous profits made by a large pharmaceutical corporation at the potential cost of thousands of lives.
Author: Marcia Angell Publisher: Random House Trade Paperbacks ISBN: 0375760946 Category : Business & Economics Languages : en Pages : 354
Book Description
During her two decades at The New England Journal of Medicine, Dr. Marcia Angell had a front-row seat on the appalling spectacle of the pharmaceutical industry. She watched drug companies stray from their original mission of discovering and manufacturing useful drugs and instead become vast marketing machines with unprecedented control over their own fortunes. She saw them gain nearly limitless influence over medical research, education, and how doctors do their jobs. She sympathized as the American public, particularly the elderly, struggled and increasingly failed to meet spiraling prescription drug prices. Now, in this bold, hard-hitting new book, Dr. Angell exposes the shocking truth of what the pharmaceutical industry has become–and argues for essential, long-overdue change. Currently Americans spend a staggering $200 billion each year on prescription drugs. As Dr. Angell powerfully demonstrates, claims that high drug prices are necessary to fund research and development are unfounded: The truth is that drug companies funnel the bulk of their resources into the marketing of products of dubious benefit. Meanwhile, as profits soar, the companies brazenly use their wealth and power to push their agenda through Congress, the FDA, and academic medical centers. Zeroing in on hugely successful drugs like AZT (the first drug to treat HIV/AIDS), Taxol (the best-selling cancer drug in history), and the blockbuster allergy drug Claritin, Dr. Angell demonstrates exactly how new products are brought to market. Drug companies, she shows, routinely rely on publicly funded institutions for their basic research; they rig clinical trials to make their products look better than they are; and they use their legions of lawyers to stretch out government-granted exclusive marketing rights for years. They also flood the market with copycat drugs that cost a lot more than the drugs they mimic but are no more effective. The American pharmaceutical industry needs to be saved, mainly from itself, and Dr. Angell proposes a program of vital reforms, which includes restoring impartiality to clinical research and severing the ties between drug companies and medical education. Written with fierce passion and substantiated with in-depth research, The Truth About the Drug Companies is a searing indictment of an industry that has spun out of control.
Author: Katherine Eban Publisher: HarperCollins ISBN: 0063054108 Category : Medical Languages : en Pages : 512
Book Description
A NEW YORK TIMES BESTSELLER New York Times 100 Notable Books of 2019 New York Public Library Best Books of 2019 Kirkus Reviews Best Health and Science Books of 2019 Science Friday Best Books of 2019 New postscript by the author From an award-winning journalist, an explosive narrative investigation of the generic drug boom that reveals fraud and life-threatening dangers on a global scale—The Jungle for pharmaceuticals Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true? Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects. The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
Author: Merrill Goozner Publisher: Univ of California Press ISBN: 0520246705 Category : Business & Economics Languages : en Pages : 304
Book Description
"Goozner shows how drug innovation is driven by dedicated scientists intent on finding cures for diseases, not by pharmaceutical firms, whose bottom line often takes precedence over the advance of medicine. Stories of a university biochemist who spent twenty years searching for single blood protein that later became the best-selling biotech drug in the world, a government employee who discovered the causes for dozens of crippling genetic disorders, and the Department of Energy-funded research that made the Human Genome Project possible - these accounts illustrate how medical breakthroughs actually take place.".
Author: Dinesh Singh Thakur
Author: Dinesh Singh Thakur
Author: Merrill Goozner
Author: Shannon Branch
Author: Dinesh Singh Thakur
Author: Katinka Newman
Author: Paul Ballman
Author: Tom Nesi
Author: Marcia Angell
Author: Katherine Eban
Author: Merrill Goozner