Author: Publisher: Elsevier
ISBN: 0080862039
Category : Medical
Languages : en
Pages : 697
Book Description
Transplantation into the Mammalian CNS
Transplantation into the Mammalian CNS
Author: Publisher: Elsevier
ISBN: 0080862039
Category : Medical
Languages : en
Pages : 697
Book Description
Transplantation into the Mammalian CNS
Transplantation in the Mammalian CNS
Author: Neural Grafting in the Mammalian CNS
Author: Anders BjörklundPublisher: Elsevier Publishing Company
ISBN:
Category : Medical
Languages : en
Pages : 746
Book Description
Neural Transplants
Author: John R. SladekPublisher:
ISBN: 9781468446869
Category :
Languages : en
Pages : 488
Book Description
Neural Transplants
Author: John R. SladekPublisher: Springer Science & Business Media
ISBN: 1468446851
Category : Medical
Languages : en
Pages : 468
Book Description
The story of mammalian neural transplantation really begins eighty-one years ago. In Chicago in December of 1903, a 34-year-old physician, Elizabeth Hopkins Dunn, working as a research assistant in neurology, initiated a series of experiments to examine the ability of neonatal rat cerebral tissue to survive transplantation into the brain of matched littermates. Out of 46 attempts, four clearly successful grafts were identified. The publication of Dunn's results in 1917, the first credible report to demonstrate the feasibility of mammalian CNS transplants, generated little interest. In fact, the next significant experiment in this field did not appear until 1930. The field continued to grow slowly and quietly as investigators gradually realized the value of neural trans plantation to study problems of development and plasticity in the mammalian nervous system. With the discovery in 1979 that grafted neurons were capable of appropriate and functional interactions with the host brain, interest in neural transplantation esca lated sharply. The extraordinary opportunities created by using functional neural trans plants in investigating basic issues in neurobiology, as well as the clinical implications, excited both scientists and the public. The popularity of neural transplantation has been growing rapidly in the past five years and shows no signs of abating. The present volume was designed to meet two needs created by the rapid growth of this subdiscipline of neurobiology. The first was to provide a thorough review of the experimental foundations of neural transplantation.
Neural Transplantation
Author: William J. FreedPublisher: MIT Press
ISBN: 9780262062084
Category : Central nervous system
Languages : en
Pages : 590
Book Description
After providing basic background on transplantation, brain structure, and development, the book discusses Parkinson's disease, the use of transplants to influence localized brain functions, circuit reconstruction, and genetic engineering and other future technologies.
Transplantation of Immortalized Glial Cells Into the Mammalian Central Nervous System
Author: Godwin S. OkoyeAxonal Regeneration in the Mammalian Central Nervous System
Author: Dorothy E. OorschotPublisher: Springer Science & Business Media
ISBN: 3642751083
Category : Medical
Languages : en
Pages : 196
Book Description
This state-of-the-art review links the experimental data into a cohesive and critical account of CNS regeneration. Research findings are discussed in terms of their relevance to one (or more) of thirteen hypotheses concerned with regeneration in the mammalian CNS. Research findings reviewed include: regeneration in developing mammals and in submammalian vertebrates, the use of transplants and/or pharmacological treatments, in vitro studies on neurotrophic and neurite promoting factors and their potential relevance to CNS regeneration in vivo, and in vitro studies on the types of glial cells that may be responsible for enhancing or suppressing axonal re-growth.
Neural Transplantation
Author: Stephen B. DunnettPublisher: Irl Press
ISBN: 9780199632855
Category : Nerve tissue
Languages : en
Pages : 211
Book Description
This is a practical introduction to the techniques of neural transplantation in mammalian brain tissue. It provides a detailed description of the techniques, written by acknowledged experts in the field, with practical details and hints complementing the underlying principles. Each chapter identifies the equipment needed, the preparations to be made in advance, and step-by-step protocols for each procedure. All aspects of neural transplantation surgery are covered, from staging and dissection of embryonic CNS tissues, through the preparation of tissues for implantation, to the transplant surgery itself. A variety of different methods for solid and cell suspension transplantation are covered. Specialized chapters consider genetic engineering of cells, labelling of grafts, and other aspects of tissue manipulation of PNS and gilal tissues; transplantation in neonatal animals, including primates; handling of human embryonic tissues for transplantation; and immunological considerations. The book will be of interest to neuroscientists studying neural development, anatomical plasticity, functional organization, and recovery in the mammalian CNS, and to neurologists and neurosurgeons interested in developing clinical applications of neural transplantation. It should be stressed that these techniques are experimental and not yet for clinical use.
Functional Neural Transplantation
Author: Stephen B. DunnettPublisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 616
Book Description