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Translational Neuro-Oncology

Translational Neuro-Oncology PDF Author: Santosh Kesari
Publisher: Academic Press
ISBN: 012813206X
Category : Science
Languages : en
Pages : 300

Book Description
More than 18,000 Americans develop a brain or neurologic tumor annually and the number of patients with metastatic brain tumors continues to grow. The need for better treatments and management strategies for brain cancer is acute. In order to cure patients, there is a clear urgency to gain a better molecular and biological understanding of the disease. Translational Neuro-Oncology provides a comprehensive overview of the research being conducted to translate science from the laboratory to create improved therapies for patients living with malignant gliomas and other brain tumors. This book discusses how integrating clinical, pre-clinical and basic science will improve the understanding of brain tumor biology and ultimately bring innovative, personalized treatments to individual patients. Chapters are organized by disease and cover recent translational research in different therapies such as chemotherapy, stem cells, immunotherapies and surgical techniques. First comprehensive book to cover translational research being conducted in neuro-oncology Discusses how to integrate basic and clinical sciences to bring innovative, personalized treatment directly to patients. Chapters organized by disease and written by both scientist and physician co-authors to promote translational synergy.

Translational Neuro-Oncology

Translational Neuro-Oncology PDF Author: Santosh Kesari
Publisher: Academic Press
ISBN: 012813206X
Category : Science
Languages : en
Pages : 300

Book Description
More than 18,000 Americans develop a brain or neurologic tumor annually and the number of patients with metastatic brain tumors continues to grow. The need for better treatments and management strategies for brain cancer is acute. In order to cure patients, there is a clear urgency to gain a better molecular and biological understanding of the disease. Translational Neuro-Oncology provides a comprehensive overview of the research being conducted to translate science from the laboratory to create improved therapies for patients living with malignant gliomas and other brain tumors. This book discusses how integrating clinical, pre-clinical and basic science will improve the understanding of brain tumor biology and ultimately bring innovative, personalized treatments to individual patients. Chapters are organized by disease and cover recent translational research in different therapies such as chemotherapy, stem cells, immunotherapies and surgical techniques. First comprehensive book to cover translational research being conducted in neuro-oncology Discusses how to integrate basic and clinical sciences to bring innovative, personalized treatment directly to patients. Chapters organized by disease and written by both scientist and physician co-authors to promote translational synergy.

Handbook of Neuro-Oncology Neuroimaging

Handbook of Neuro-Oncology Neuroimaging PDF Author: Herbert B. Newton
Publisher: Academic Press
ISBN: 0128229950
Category : Medical
Languages : en
Pages : 1022

Book Description
With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this third edition of the Handbook of Neuro-Oncology Neuroimaging is very relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuroimaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the second edition, and in addition features several new important chapters covering diverse topics such as imaging for the use of Laser Interstitial Thermal Therapy, advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. Sections first overview neuro-oncological disorders before delving into the physics and basic science of neuroimaging and great focus on CT and MRI. The book then focuses on advances in the neuroimaging of brain tumors and neuroimaging of specific tumor types. There is also discussion of neuroimaging of other neuro-oncological syndromes. This book will serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology. Summarizes translational research on brain imaging for brain tumors Discusses limitations of neuroimaging for diagnosis and treatment Presents advanced imaging technologies, including CT, MRI, and PET Contains new coverage on Laser Interstitial Thermal Therapy, radiation therapy, clinical trials, and more

Translational Immunotherapy of Brain Tumors

Translational Immunotherapy of Brain Tumors PDF Author: John H. Sampson
Publisher: Academic Press
ISBN: 0128026251
Category : Science
Languages : en
Pages : 406

Book Description
Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These new breakthroughs, now approved by the FDA, are a part of multiple phase III international trials and ongoing research in malignant glioma, meaning that the information in this cutting-edge book will be of great importance to practitioners and researchers alike. Comprehensive overview, providing an update on immunology, translational immunotherapy, and clinical trials relating to malignant gliomas Edited by a prominent neurosurgeon with contributions by leading researchers in the field Ideal resource for researchers and practitioners interested in learning about mechanisms that use the immune system to treat brain tumors

Handbook of Neuro-Oncology Neuroimaging

Handbook of Neuro-Oncology Neuroimaging PDF Author: Herbert B. Newton
Publisher: Academic Press
ISBN: 0128011688
Category : Medical
Languages : en
Pages : 866

Book Description
Remarkable progress in neuro-oncology due to increased utilization of advanced imaging in clinical practice continues to accelerate in recent years. Refinements in magnetic resonance imaging (MRI) and computed tomography (CT) technology, and the addition of newer anatomical, functional, and metabolic imaging methods, such as MRS, fMRI, diffusion MRI, and DTI MRI have allowed brain tumor patients to be diagnosed much earlier and to be followed more carefully during treatment. With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this second edition of the Handbook of Neuro-Oncology Neuroimaging is so relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuro-Imaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the first edition, and in addition will feature several new important chapters covering diverse topics such as advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. It will also serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology. Provides a background to translational research and the use of brain imaging for brain tumors Contains critical discussions on the potential and limitations of neuroimaging as a translational tool for the diagnosis and treatment of brain tumor and neuro-oncology patients Presents an up-to-date reference on advanced imaging technologies, including computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), as well as the recent refinements in these techniques

Emerging Concepts in Neuro-Oncology

Emerging Concepts in Neuro-Oncology PDF Author: Colin Watts
Publisher: Springer Science & Business Media
ISBN: 085729458X
Category : Medical
Languages : en
Pages : 222

Book Description
Having been a fairly dormant specialty for many decades, in recent years there has been a remarkable increase in activity in Neuro-oncology from basic science through to the clinics. Reflecting this there have been considerable advancements in the understanding of the biology of CNS malignancies which have infirmed the development of many novel and successful therapies. This work aims to bring together the scattered literature on the new concepts in neuro-oncology for the benefit of those in the field. The book moves from concepts in the scientific basis of neuro-oncology, through to modelling techniques and finishing on the translation into clinical practice.

Textbook of Neuro-oncology

Textbook of Neuro-oncology PDF Author: Mitchel S. Berger
Publisher: Saunders
ISBN:
Category : Medical
Languages : en
Pages : 884

Book Description
This new resource presents today's most comprehensive, multidisciplinary coverage of cancers of the central and peripheral nervous system. Experts in neurosurgery, neuroradiology, neuropathology, neuro-oncology, and all other relevant fields present well-rounded, in-depth, cutting-edge information on epidemiology, diagnosis, and treatment for each type of tumor entity. This practical organization allows readers to efficiently access complete clinical knowledge on any form of neurological cancer.

Oncology of CNS Tumors

Oncology of CNS Tumors PDF Author: Jörg-Christian Tonn
Publisher: Springer Science & Business Media
ISBN: 3642028748
Category : Medical
Languages : en
Pages : 776

Book Description
Knowledge about the etiology and diagnosis as well as treatment concepts of neu- oncologic diseases is rapidly growing. This turnover of knowledge makes it dif? cult for the physician engaged in the treatment to keep up to date with current therapies. This book sets out to close the gap and pursues several innovative concepts. As a comprehensive text on neuro-oncology, its chapters are interconnected, but at the same time some chapters or subdivisions are so thoroughly assembled that the whole volume gives the impression of several books combined into one. Neuropathology is treated in an extensive and clearly structured section. The int- ested reader ? nds for each tumor entity the latest well-referenced consensus rega- ing histologic and molecular pathology. Through this “book-in-the-book” concept, information on neuropathology is readily at hand in a concise form and without ov- loading the single chapters. Pediatric neuro-oncology differs in many entities from tumors in adult patients; also, certain tumors of the CNS are typically or mainly found only in the child. Therefore, pediatric neuro-oncology was granted its own, book-like section. Tumor entities that are treated differently in children and adults are included both in the pediatric neuro-oncology section and in the general section. Entities that typically occur only in the child and adolescent are found in the pediatric section in order to avoid redundancies.

Clinical Molecular Diagnostics

Clinical Molecular Diagnostics PDF Author: Shiyang Pan
Publisher: Springer Nature
ISBN: 9811610371
Category : Medical
Languages : en
Pages : 889

Book Description
This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs. It lets readers to understand and realize precision healthcare.

Neuro-oncology

Neuro-oncology PDF Author: Roger J. Packer
Publisher: John Wiley & Sons
ISBN: 0470655755
Category : Medical
Languages : en
Pages : 272

Book Description
Cancer imposes daunting effects on the nervous system Brain cancer is one of the most devastating diagnoses a physician can deliver. Cancer of the nervous system can take many different forms. Treatment is specific to the type of malignancy, its location in the nervous system and, increasingly, its molecular characteristics. The challenges manifest further when management choices need to be made, and multidisciplinary approaches are required. Additional complexities arise in children, where the developing neurological system requires more sensitive treatment. Neuro-oncology unmasks the complexities to provide a straightforward guide to cancers of the nervous system. Following a general approach to diagnosis and treatment, the clinical aspects of specific cancer types in adults and children are explained in practical terms. A final section considers the effect of system cancer on the nervous system and the side effects of treatment. Clinical in approach, practical in execution, Neuro-oncology will help you diagnose and manage your patients more effectively. Neurology in Practice Series Editors Robert A Gross , MD, PhD, Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA Jonathan W Mink, MD, PhD, Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA The Neurology in Practice series provides clinical 'in the office' or 'at the bedside' guides to effective patient care for neurologists. The tone is practical, not academic, with authors offering guidance on what might be done and what should be avoided. The books are informed by evidence-based practice and feature: Algorithms and guidelines where they are appropriate 'Tips and Tricks' boxes – hints on improving outcomes 'Caution' warning boxes – hints on avoiding complications 'Science Revisited' – quick reminder of the basic science principles Summaries of key evidence and suggestions for further reading

Neuro-Oncology: The Essentials

Neuro-Oncology: The Essentials PDF Author: Mark Bernstein
Publisher: Thieme
ISBN: 1604068841
Category : Medical
Languages : en
Pages : 1330

Book Description
Neuro-Oncology: The Essentials, Third Edition, is a comprehensive introduction to the fundamental science and core clinical concepts behind the successful multidisciplinary management of patients with brain and spine tumors. Among the updates to this new edition are eight new chapter topics, including: Endoscopic Approaches, Pediatric Supratentorial Tumors, and Neuro-Oncology in the Developing World. The book begins with basic science, progresses to clinical applications, and includes a robust section on specific tumor types. Key Features: A major revision, with a 20% increase in content and over 35% increase in figures Editors Notes at the end of each chapter briefly summarize a topic, provide a historical perspective on a topic, add a current reference, or highlight salient points Demonstrates the latest surgical navigation techniques, including stereotaxy and intraoperative MRI, used to access hard-to-reach tumors This new edition is an invaluable reference for all neurosurgeons, neurologists, and oncologists, as well as residents and fellows, and it will be a treasured volume in their medical libraries for years to come.