Transients and Bifurcations of the Mammalian Circadian System PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Transients and Bifurcations of the Mammalian Circadian System PDF full book. Access full book title Transients and Bifurcations of the Mammalian Circadian System by Adrián E. Granada. Download full books in PDF and EPUB format.
Author: Adrián E. Granada Publisher: Logos Verlag Berlin GmbH ISBN: 3832529667 Category : Science Languages : en Pages : 143
Book Description
Many organisms have an endogenous oscillatory system that controls their daily rhythms in physiology, metabolism and behaviour. In mammals, these oscillations are found in almost every cell and are orchestrated by a tiny brain area: the suprachiasmatic nucleus (SCN). This central pacemaker contains thousands of heterogeneous neurons that oscillate in a synchronized fashion and generate a robust about-a-day pace for the body. One of the fundamental properties of the SCN is to keep its internal period in synchrony with the external 24 hour environmental cycle, i.e., to entrain to the external recurring environment. Many properties of this complex network of coupled entrainable oscillators are poorly understood and the present work deals with some of these open questions.
Author: Adrián E. Granada Publisher: Logos Verlag Berlin GmbH ISBN: 3832529667 Category : Science Languages : en Pages : 143
Book Description
Many organisms have an endogenous oscillatory system that controls their daily rhythms in physiology, metabolism and behaviour. In mammals, these oscillations are found in almost every cell and are orchestrated by a tiny brain area: the suprachiasmatic nucleus (SCN). This central pacemaker contains thousands of heterogeneous neurons that oscillate in a synchronized fashion and generate a robust about-a-day pace for the body. One of the fundamental properties of the SCN is to keep its internal period in synchrony with the external 24 hour environmental cycle, i.e., to entrain to the external recurring environment. Many properties of this complex network of coupled entrainable oscillators are poorly understood and the present work deals with some of these open questions.
Author: David C. Klein Publisher: Oxford University Press, USA ISBN: 9780195062502 Category : Medical Languages : en Pages : 498
Book Description
Based on a conference funded by the National Institutes of Health, this timely book is the most up-to-date and definitive reference on the suprachiasmatic nucleus (SCN), the part of the brain that controls circadian rhythms in mammals. These biological rhythms range from daily fluctuations in metabolism to seasonal and annual cycles. This book comprehensive and incisive review of the SCN covers anatomy and physiology, intrinsic SCN rhythms, circadian rhythms, neuropharmacology, transplants, and development.
Author: Karl Johan Åström Publisher: Princeton University Press ISBN: 069121347X Category : Technology & Engineering Languages : en Pages :
Book Description
The essential introduction to the principles and applications of feedback systems—now fully revised and expanded This textbook covers the mathematics needed to model, analyze, and design feedback systems. Now more user-friendly than ever, this revised and expanded edition of Feedback Systems is a one-volume resource for students and researchers in mathematics and engineering. It has applications across a range of disciplines that utilize feedback in physical, biological, information, and economic systems. Karl Åström and Richard Murray use techniques from physics, computer science, and operations research to introduce control-oriented modeling. They begin with state space tools for analysis and design, including stability of solutions, Lyapunov functions, reachability, state feedback observability, and estimators. The matrix exponential plays a central role in the analysis of linear control systems, allowing a concise development of many of the key concepts for this class of models. Åström and Murray then develop and explain tools in the frequency domain, including transfer functions, Nyquist analysis, PID control, frequency domain design, and robustness. Features a new chapter on design principles and tools, illustrating the types of problems that can be solved using feedback Includes a new chapter on fundamental limits and new material on the Routh-Hurwitz criterion and root locus plots Provides exercises at the end of every chapter Comes with an electronic solutions manual An ideal textbook for undergraduate and graduate students Indispensable for researchers seeking a self-contained resource on control theory
Author: Domitilla Del Vecchio Publisher: Princeton University Press ISBN: 1400850509 Category : Science Languages : en Pages : 287
Book Description
This book provides an accessible introduction to the principles and tools for modeling, analyzing, and synthesizing biomolecular systems. It begins with modeling tools such as reaction-rate equations, reduced-order models, stochastic models, and specific models of important core processes. It then describes in detail the control and dynamical systems tools used to analyze these models. These include tools for analyzing stability of equilibria, limit cycles, robustness, and parameter uncertainty. Modeling and analysis techniques are then applied to design examples from both natural systems and synthetic biomolecular circuits. In addition, this comprehensive book addresses the problem of modular composition of synthetic circuits, the tools for analyzing the extent of modularity, and the design techniques for ensuring modular behavior. It also looks at design trade-offs, focusing on perturbations due to noise and competition for shared cellular resources. Featuring numerous exercises and illustrations throughout, Biomolecular Feedback Systems is the ideal textbook for advanced undergraduates and graduate students. For researchers, it can also serve as a self-contained reference on the feedback control techniques that can be applied to biomolecular systems. Provides a user-friendly introduction to essential concepts, tools, and applications Covers the most commonly used modeling methods Addresses the modular design problem for biomolecular systems Uses design examples from both natural systems and synthetic circuits Solutions manual (available only to professors at press.princeton.edu) An online illustration package is available to professors at press.princeton.edu
Author: Pablo A. Iglesias Publisher: MIT Press ISBN: 0262013347 Category : Biological control systems Languages : en Pages : 359
Book Description
A survey of how engineering techniques from control and systems theory can be used to help biologists understand the behavior of cellular systems.
Author: Alan Garfinkel Publisher: Springer ISBN: 3319597310 Category : Mathematics Languages : en Pages : 456
Book Description
This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?
Author: Christopher P. Fall Publisher: Springer Science & Business Media ISBN: 0387224599 Category : Science Languages : en Pages : 484
Book Description
This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throughout the text. Appendices containing mathematical and computational techniques are provided as a reference tool.
Author: Adrián E. Granada
Author: Adrián E. Granada
Author: 
Author: David C. Klein
Author: 
Author: Karl Johan Åström
Author: Domitilla Del Vecchio
Author: Society for Neuroscience. Annual Meeting
Author: Pablo A. Iglesias
Author: Alan Garfinkel
Author: Christopher P. Fall