Author: Publisher:
ISBN:
Category : Nitro compounds
Languages : en
Pages : 136
Book Description
Toxicological Profile for Nitrophenols
Author: Toxicological Profile for Polycyclic Aromatic Hydrocarbons
Author: Publisher:
ISBN:
Category : Polycyclic aromatic hydrocarbons
Languages : en
Pages : 500
Book Description
Toxicological Profile for Hexachlorobutadiene
Author: Taking an Exposure History
Author: Arthur L. FrankPublisher:
ISBN:
Category : Environmental monitoring
Languages : en
Pages : 60
Book Description
Toxicological Profile for Di-n-butyl Phthalate
Author: Phthalates and Cumulative Risk Assessment
Author: National Research CouncilPublisher: National Academies Press
ISBN: 0309128412
Category : Nature
Languages : en
Pages : 208
Book Description
People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.
Toxicological Profile for N-nitrosodimethylamine
Author: Toxicological Profile for Pyrethrins and Pyrethroids
Author: Publisher:
ISBN:
Category : Health risk assessment
Languages : en
Pages : 334
Book Description
Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals
Author: National Academies of Sciences, Engineering, and MedicinePublisher: National Academies Press
ISBN: 0309458625
Category : Science
Languages : en
Pages : 423
Book Description
To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects.
Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water
Author: IARC Working Group on the Evaluation of Carcinogenic Risks to HumansPublisher: IARC Monographs on the Evaluat
ISBN: 9789283213246
Category : Medical
Languages : en
Pages : 0
Book Description
This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.