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Author: Harold Dumont Publisher: ISBN: Category : Languages : fr Pages : 222
Book Description
La chimiothérapie orale est déjà ancienne mais avec la multiplication des molécules disponibles par voie orale, elle connaît actuellement un engouement nouveau. Les arguments en faveur de la voie orale sont nombreux. Tout d'abord, cette voie correspond au choix des patients, de plus elle permet l'administration de cytotoxiques au long cours et en continu, et enfin elle rend possible des économies en diminuant les coûts d'administration. Néanmoins, les oncologues conservent parfois des idées négatives sur les chimiothérapies orales. Les deux principales critiques sont que les médicaments oraux possèdent souvent une faible et imprédictible biodisponibilité et que la compliance des patients aux traitements est incertaine. Ce travail prend notamment l'exemple du développement de l'étoposide pour la voie orale. L' étude des perspectives à venir des médicaments oraux, nous permet de supposer que le développement de cette voie constituera l'une des grandes évolutions du traitement du cancer.
Author: Harold Dumont Publisher: ISBN: Category : Languages : fr Pages : 222
Book Description
La chimiothérapie orale est déjà ancienne mais avec la multiplication des molécules disponibles par voie orale, elle connaît actuellement un engouement nouveau. Les arguments en faveur de la voie orale sont nombreux. Tout d'abord, cette voie correspond au choix des patients, de plus elle permet l'administration de cytotoxiques au long cours et en continu, et enfin elle rend possible des économies en diminuant les coûts d'administration. Néanmoins, les oncologues conservent parfois des idées négatives sur les chimiothérapies orales. Les deux principales critiques sont que les médicaments oraux possèdent souvent une faible et imprédictible biodisponibilité et que la compliance des patients aux traitements est incertaine. Ce travail prend notamment l'exemple du développement de l'étoposide pour la voie orale. L' étude des perspectives à venir des médicaments oraux, nous permet de supposer que le développement de cette voie constituera l'une des grandes évolutions du traitement du cancer.
Author: Carole Fakhry Publisher: Thieme ISBN: 162623969X Category : Medical Languages : en Pages : 1241
Book Description
A state-of-the-art guide on oral cancer management from distinguished experts! Oral Cancer: Evaluation, Therapy, and Rehabilitation edited by prominent Johns Hopkins clinicians and educators Carole Fakhry, Karen Pitman, Ana Kiess, and David Eisele provides a comprehensive, state-of-the-art review on the diagnosis and management of oral cancer. This unique resource fills a void in the literature by exploring surgical and reconstructive issues specific to each subsite of the oral cavity. Important pre- and post-treatment evaluations by dental, speech language pathology, and the oncologic care team are reviewed. The comprehensive book is divided into 10 sections, each focused on different facets of the patients' trajectory. The text starts with epidemiology of oral cavity cancer and discussion of patient populations at increased risk of oral cavity cancer. The book details pre-cancers, multidisciplinary diagnostic evaluations, treatment, post-treatment, recurrent and metastatic oral cancer, and palliative care, concluding with future directions such as chemoprevention. A full spectrum of oral neoplasms are covered in depth, including different types of squamous cell cancer, primary malignancies of the mandible, and sublingual and minor salivary gland malignancies. Key Features All oral cavity subsites are approached from both an ablative and reconstructive standpoint, with dedicated chapters focused on specific oral cancer reconstructive techniques Discussion of oncologic considerations encompassing radiation and medical oncology including definitive radiation therapy, brachytherapy, adjuvant radiation therapy, and adjuvant chemotherapy/novel therapeutics Clinical pearls cover complications of both surgery and radiation therapy, as well as psychological and dental implications of therapy High-quality illustrations, photographs, and videos further elucidate impacted anatomy and techniques Residents and clinicians in otolaryngology-head and neck surgery, oral and maxillofacial surgery, head and neck reconstructive surgery, medical oncology, and radiation oncology will benefit from reading this excellent resource. Dentists who wish to further their knowledge about oral cancers will also find it an invaluable reference.
Book Description
Les enfants et les adolescents atteints de cancers sont amenés à prendre de nombreux médicaments par voie orale tout au long de leur prise en charge et l'essor des thérapies ciblées va contribuer dans les prochaines années à accentuer ce constat. Le patient devient acteur de sa prise en charge et cela implique qu'il soit autonome dans la gestion de son traitement. Une étude des besoins des patients et des familles suivis en oncologie pédiatrique a été réalisée concernant les prises médicamenteuses per os à domicile. 17 patients et familles suivis en oncologie pédiatrique au CHU de Caen ont été interrogés à l'aide d'un questionnaire rédigé en concertation avec l'équipe médicale. Quatre thèmes ont été abordés : connaissances et compréhension du traitement médicamenteux, explications du traitement par l'équipe médicale, prise du traitement à domicile et outils pédagogiques. L'étude a relevé différents besoins dont voici les principaux : la conduite à tenir en cas de vomissement ou d'oubli d'une prise, l'utilisation de la phytothérapie et ses interactions, des demandes de supports type plan de prise et fiches informatives sur les médicaments. Pour répondre à ses besoins, un programme d'éducation thérapeutique du patient déjà existant sur les chimiothérapies orales a été adapté à l'oncologie pédiatrique. Un plan de prise a été réalisé et des fiches explicatives sur les chimiothérapies orales ont été diffusées. Des recommandations d'usage sur la phytothérapie ont été transmises par un flyer adapté pour le service. Pour l'avenir, il serait intéressant de mettre en place des consultations pharmaceutiques d'autant plus que les familles et le service de soin sont intéressés par ce type d'intervention.
Author: Sudhir Bahadur Publisher: Springer ISBN: 9789811564987 Category : Medical Languages : en Pages : 0
Book Description
Tumor biology varies at different subsites in the oral cavity, and therefore carcinoma of the gingivo-buccal sulcus (also known as Indian cancer) behaves differently from carcinoma of the tongue. Oral cancer is very often diagnosed at an advanced stage with neck metastasis, and most cases have a guarded prognosis. Loco-regional recurrences are frequent and morbidity following treatment is considerable. However, results have improved in recent years, particularly in early and certain advanced stages, due to better imaging and case selection, improved surgical techniques, including those for reconstructive surgery, a multidisciplinary team approach and a better understanding of tumor biology and prognostic factors. This book comprehensively and systematically reviews all these aspects of diagnostic and therapeutic advances in oral cancer, particularly discussing early detection, epidemiology, chemoprevention and current research. Written by specialists who are active leaders in basic sciences or clinical fields, the chapters address individual and collective issues in managing patients with oral cancer, and provide insights into various treatment approaches. The authors share their knowledge and experience and provide extensive literature sources to encourage clinicians to be flexible, innovative and help them make the best, educated decisions for individual patients.
Author: Giuseppe Giaccone Publisher: CRC Press ISBN: 1842145452 Category : Medical Languages : en Pages : 500
Book Description
Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edition provides a concise timely panorama of existing targeted therapies and progress into future anticancer treatments. These therapies notably include: Targeted agents of immune checkpoints Signal-transduction inhibitors Antiangiogenic agents Vascular-disrupting agents Apoptosis modulators Stem cell inhibitors Tumor profiling for drug development The book emphasizes the biology behind this new class of drugs as well as the clinical achievements obtained. The contributors to this volume stand at the cutting edge of cancer research and treatment around the world.
Author: Ann Berger Publisher: Lippincott Williams & Wilkins ISBN: 1975143701 Category : Medical Languages : en Pages : 1877
Book Description
The only book on the market to cover palliative care for both adults and children, Pediatric and Adult Palliative Care and Support Oncology offers an easy-to-read, interdisciplinary approach to supportive oncology as well as end-of-life care. Ideal for oncologists, residents, fellows, nurse practitioners, and physician assistants, the fifth edition provides important updates for conventional topics while also featuring several brand new chapters. Covering everything from dermatologic toxicity of cancer treatment to running family meetings for setting goals of care, this unique title is a source of both help and inspiration to all those who care for patients with cancer.
Author: Françoise Charnay-Sonnek Publisher: Springer ISBN: 3319764578 Category : Medical Languages : en Pages : 454
Book Description
This book provides a unique overview of oncology nursing care in a new health environment, one in which oncology nurses play an increasingly important role. In this regard, it addresses not only the biomedical aspects of new drugs but also the challenges they pose in day-to-day nursing practice. It also highlights the new skills that oncology nurses will need to develop in light of the changing care setting. Drawing on evidence-based practice in Europe and around the globe, the book offers a holistic approach to nursing for adult and pediatric patients. Written by respected professionals in the field, it provides nurses interested in oncology with clear and comprehensive information on the specific abilities required, with a focus on therapeutic education, supportive care, genetic counseling and e-health. In addition, it addresses the new role of patients as decision makers and full partners throughout their treatment cycle.
Author: National Academies of Sciences Engineering and Medicine Publisher: ISBN: 9780309683494 Category : Languages : en Pages :
Book Description
Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
Author: Pat Price Publisher: CRC Press ISBN: 0340912219 Category : Medical Languages : en Pages : 1517
Book Description
Since the first edition was published in 1982, Treatment of Cancer has become a standard text for postgraduate physicians in the UK and beyond, providing all information necessary for modern cancer management in one comprehensive but accessible volume. By inviting experts from a number of disciplines to share their knowledge, the editors have succeeded in delivering a truly integrated approach to the care of the patient with cancer. This fifth edition adopts the successful structure of previous editions, whilst being thoroughly revised and updated, and with several completely new chapters, covering important topics such as drug development, cancer prevention, and economics of cancer care, as well as treatments such as radioimmunotherapy, biological therapies and antibody therapy. Part One considers the scientific basis and fundamental principles underlying cancer treatment and examines the likely developments that will occur over the next decade at the leading edge of oncology. Part Two is divided into two sections; the first covering general issues of cancer management, including planning techniques, concomitent chemoradiotherapy, surgical oncology and palliative care; and the second using a system-based approach to cover the clinical aspects and management plans for the whole spectrum of malignant disease. Treatment of Cancer surpasses other oncology texts in condensing the essential information for exemplary cancer care into one readable and accessible guide, and will be an invaluable addition to the bookshelves of the busy oncologist in training or in practice.
Author: Shahrokh F. Shariat Publisher: Springer ISBN: 1493915010 Category : Medical Languages : en Pages : 206
Book Description
Upper Tract Urothelial Carcinoma represents the first book of its kind to be dedicated solely to UTUC. It's aim is to improve understanding and eventually care of a disease that is greatly understudied and underappreciated, yet commonly dealt with by many medical and urologic oncologists. The volume features new data regarding genetic susceptibility, gene expression studies and causative factors; contemporary concepts and controversies regarding diagnosis and staging of UTUC; prediction tools and their value in treatment decisions within each disease stage and patient selection and treatment options such as endoscopic management, distal ureterectomy, radical nephroureterectomy and chemotherapy. Up-to-date information regarding boundaries of surgical resection, indication and extent of lymphadenectomy is covered as well as the role of perioperative/neoadjuvant chemotherapy in patients with high-risk UTUC. Upper Tract Urothelial Carcinoma will be of great value to all Urologists, Medical Oncologists and fellows in Urologic Oncology as well as upper level residents in training in Urology and Medical Oncology.
Author: Harold Dumont
Author: Harold Dumont
Author: Carole Fakhry
Author: Mathilde Villarbu
Author: Sudhir Bahadur
Author: Giuseppe Giaccone
Author: Ann Berger
Author: Françoise Charnay-Sonnek
Author: National Academies of Sciences Engineering and Medicine
Author: Pat Price
Author: Shahrokh F. Shariat