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The Warburg Effect Regulation Under Siege: The Intertwined Pathways in Health and Disease

The Warburg Effect Regulation Under Siege: The Intertwined Pathways in Health and Disease PDF Author: Concetta Bubici
Publisher: Frontiers Media SA
ISBN: 2889630013
Category :
Languages : en
Pages : 128

Book Description
Many cells, including immune, neuronal, cancer and stem cells, become dependent on aerobic glycolysis to escape apoptosis and accommodate their bioenergetics needs. How this metabolic change, also known as the Warburg effect, is regulated remains largely unknown. The Warburg effect has been widely investigated in cancer cells where it was first observed with the aim of decoding the molecular networks controlling its activation for therapeutic purposes. This Research Topic aimed to discuss and review all the intracellular signaling regulating the Warburg effect in cancerous and normal non-cancerous cells though original research articles, mini reviews and reviews.

The Warburg Effect Regulation Under Siege: The Intertwined Pathways in Health and Disease

The Warburg Effect Regulation Under Siege: The Intertwined Pathways in Health and Disease PDF Author: Concetta Bubici
Publisher: Frontiers Media SA
ISBN: 2889630013
Category :
Languages : en
Pages : 128

Book Description
Many cells, including immune, neuronal, cancer and stem cells, become dependent on aerobic glycolysis to escape apoptosis and accommodate their bioenergetics needs. How this metabolic change, also known as the Warburg effect, is regulated remains largely unknown. The Warburg effect has been widely investigated in cancer cells where it was first observed with the aim of decoding the molecular networks controlling its activation for therapeutic purposes. This Research Topic aimed to discuss and review all the intracellular signaling regulating the Warburg effect in cancerous and normal non-cancerous cells though original research articles, mini reviews and reviews.

Luxury Arts of the Renaissance

Luxury Arts of the Renaissance PDF Author: Marina Belozerskaya
Publisher: Getty Publications
ISBN: 0892367857
Category : Art
Languages : en
Pages : 292

Book Description
Today we associate the Renaissance with painting, sculpture, and architecture—the “major” arts. Yet contemporaries often held the “minor” arts—gem-studded goldwork, richly embellished armor, splendid tapestries and embroideries, music, and ephemeral multi-media spectacles—in much higher esteem. Isabella d’Este, Marchesa of Mantua, was typical of the Italian nobility: she bequeathed to her children precious stone vases mounted in gold, engraved gems, ivories, and antique bronzes and marbles; her favorite ladies-in-waiting, by contrast, received mere paintings. Renaissance patrons and observers extolled finely wrought luxury artifacts for their exquisite craftsmanship and the symbolic capital of their components; paintings and sculptures in modest materials, although discussed by some literati, were of lesser consequence. This book endeavors to return to the mainstream material long marginalized as a result of historical and ideological biases of the intervening centuries. The author analyzes how luxury arts went from being lofty markers of ascendancy and discernment in the Renaissance to being dismissed as “decorative” or “minor” arts—extravagant trinkets of the rich unworthy of the status of Art. Then, by re-examining the objects themselves and their uses in their day, she shows how sumptuous creations constructed the world and taste of Renaissance women and men.

Epistemologies of the South

Epistemologies of the South PDF Author: Boaventura de Sousa Santos
Publisher: Routledge
ISBN: 1317260341
Category : Political Science
Languages : en
Pages : 285

Book Description
This book explores the concept of 'cognitive injustice': the failure to recognise the different ways of knowing by which people across the globe run their lives and provide meaning to their existence. Boaventura de Sousa Santos shows why global social justice is not possible without global cognitive justice. Santos argues that Western domination has profoundly marginalised knowledge and wisdom that had been in existence in the global South. She contends that today it is imperative to recover and valorize the epistemological diversity of the world. Epistemologies of the South outlines a new kind of bottom-up cosmopolitanism, in which conviviality, solidarity and life triumph against the logic of market-ridden greed and individualism.

The Renewal of Pagan Antiquity

The Renewal of Pagan Antiquity PDF Author: Aby Warburg
Publisher: Getty Publications
ISBN: 9780892365371
Category : Art, Renaissance
Languages : en
Pages : 872

Book Description
A collection of essays by the art historian Aby Warburg, these essays look beyond iconography to more psychological aspects of artistic creation: the conditions under which art was practised; its social and cultural contexts; and its conceivable historical meaning.

Life Over Cancer

Life Over Cancer PDF Author: Keith Block
Publisher: Bantam
ISBN: 0553801147
Category : Health & Fitness
Languages : en
Pages : 610

Book Description
Dr. Keith Block is at the global vanguard of innovative cancer care. As medical director of the Block Center for Integrative Cancer Treatment in Evanston, Illinois, he has treated thousands of patients who have lived long, full lives beyond their original prognoses. Now he has distilled almost thirty years of experience into the first book that gives patients a systematic, research-based plan for developing the physical and emotional vitality they need to meet the demands of treatment and recovery. Based on a profound understanding of how body and mind can work together to defeat disease, this groundbreaking book offers: • Innovative approaches to conventional treatments, such as “chronotherapy”–chemotherapy timed to patients’ unique circadian rhythms for enhanced effectiveness and reduced toxicity • Dietary choices that make the biochemical environment hostile to cancer growth and recurrence, and strengthen the immune system’s ability to attack remaining cancer cells • Precise supplement protocols to tame treatment side effects, relieve disease-related symptoms, and modify processes like inflammation and glycemia that can fuel cancer if left untreated • A new paradigm for exercise and stress reduction that restores your strength, reduces anxiety and depression, and supports the body’s own ability to heal • A complete program for remission maintenance–a proactive plan to make sure the cancer never returns Also included are “quick-start” maps to help you find the information you need right now and many case histories that will support and inspire you. Encouraging, compassionate, and authoritative, Life over Cancer is the guide patients everywhere have been waiting for.

Historical Perspectives of the Operational Art

Historical Perspectives of the Operational Art PDF Author: Michael D. Krause
Publisher: Government Printing Office
ISBN: 9780160725647
Category : History
Languages : en
Pages : 520

Book Description
NOTE: NO FURTHER DISCOUNT FOR THIS PRINT PRODUCT--OVERSTOCK SALE -- Significantly reduced list price while supplies last Historical Perspectives of the Operational Art, a companion volume to Clayton R. Newell's and Michael D. Krause's On Operational Art, captures the doctrinal debate over the evolving concept of operational art-the critical link between strategy and tactics-in the face of the new complexities of warfare and the demands of irregular operations in the twenty-first century. Consisting of fifteen original essays selected and edited by Michael D. Krause in collaboration with R. Cody Phillips, the well-organized anthology presents the collective view of distinguished military historians and scholars that operational art must be adjusted to accommodate the changing circumstances happening around the world, especially when dealing with broad coalitions and alliances in regional environments and at an international level. Related products: The Rise of iWar: Identity, Information, and the Individualization of Modern Warfare can be found here: https://bookstore.gpo.gov/products/sku/008-000-01198-2 Yemen: A Different Political Paradigm in Context can be found here: https://bookstore.gpo.gov/products/sku/008-070-00865-3 A Masterpiece of Counterguerrilla Warfare: BG J. Franklin Bell in the Philippines 1901-1902 is avaialble here: https://bookstore.gpo.gov/products/sku/008-000-01000-5 Operational Culture for the Warfighter: Principles and Applications is available here: https://bookstore.gpo.gov/products/sku/008-000-01061-7

United States Army Logistics, 1775-1992

United States Army Logistics, 1775-1992 PDF Author: Charles R. Shrader
Publisher:
ISBN:
Category : Logistics
Languages : en
Pages : 352

Book Description


Towards a New Enlightenment?

Towards a New Enlightenment? PDF Author:
Publisher: Turner
ISBN: 9788417141219
Category : Social Science
Languages : en
Pages : 0

Book Description
Addresses key issues in understanding the decade 2008-2018 and its impact on the societies of the future. Brings together the articles B28of twenty-two prestigious international experts in different fields of thought. Through an informative approach, the essays form a transversal view of today's thinking. This is the tenth title of the Open Mind essay collection published by BBVA. A27.0We are living through years of great importance, marked by the unstoppable evolution of technology, science and the information society. This book brings together twenty-two essays written by prestigious researchers from the world's leading universities on areas as diverse as crucial to our future: climate change, artificial intelligence, economics, cyber-security and geopolitics, democracy, anthropology, new media, astrophysics and cosmology, nanotechnology, biomedicine, globalisation, gender theory and the cities of the future.

Big Data in Organizations and the Role of Human Resource Management

Big Data in Organizations and the Role of Human Resource Management PDF Author: Tobias M. Scholz
Publisher: Peter Lang Gmbh, Internationaler Verlag Der Wissenschaften
ISBN: 9783631718902
Category : Business & Economics
Languages : en
Pages : 237

Book Description
Big data are changing the way we work. This book conveys a theoretical understanding of big data and the related interactions on a socio-technological level as well as on the organizational level. Big data challenge the human resource department to take a new role. An organization's new competitive advantage is its employees augmented by big data.

The Cambridge History of Judaism: Volume 2, The Hellenistic Age

The Cambridge History of Judaism: Volume 2, The Hellenistic Age PDF Author: William David Davies
Publisher: Cambridge University Press
ISBN: 9780521219297
Category : Religion
Languages : en
Pages : 766

Book Description
Vol. 4 covers the late Roman period to the rise of Islam. Focuses especially on the growth and development of rabbinic Judaism and of the major classical rabbinic sources such as the Mishnah, Jerusalem Talmud, Babylonian Talmud and various Midrashic collections.