Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Fluorinated Heterocyclic Compounds PDF full book. Access full book title Fluorinated Heterocyclic Compounds by Viacheslav A. Petrov. Download full books in PDF and EPUB format.
Author: Viacheslav A. Petrov Publisher: John Wiley & Sons ISBN: 047052894X Category : Science Languages : en Pages : 535
Book Description
A thorough survey of synthetic methods, chemistry, and applications of major classes of fluorinated heterocycles Merging organic, heterocyclic, and fluoroorganic chemistry, fluorinated heterocyclic compounds have distinctively desirable properties suitable for use in pharmaceuticals and agrichemicals, especially their ability to penetrate the cell membrane barrier for drug absorption. Offering a needed overview of this relatively new addition to the heterocyclic family, this essential reference provides the latest state-of-the-art information on key application areas within fluorine chemistry. With contributions from experts from both industry and academia, the book covers the chemistry, synthesis, and applications of fluorinated heterocycles with chapters on: Three-, four-, five-, six-, and seven-membered fluorine-containing heterocycles Fluorinated nucleosides Fluorointermediates Applications of fluorinated heterocycles in agricultural products Pharmaceuticals containing fluorinated heterocycles Technical applications of fluorinated heterocycles Written by a team of world-recognized experts in the area of organic and industrial chemistry of fluorine, Fluorinated Heterocyclic Compounds: Synthesis, Chemistry, and Applications will prove valuable to both students and researchers from academia and industry seeking further knowledge of the synthetic methods, chemistry, and applications of major classes of fluorinated heterocycles.
Author: Viacheslav A. Petrov Publisher: John Wiley & Sons ISBN: 047052894X Category : Science Languages : en Pages : 535
Book Description
A thorough survey of synthetic methods, chemistry, and applications of major classes of fluorinated heterocycles Merging organic, heterocyclic, and fluoroorganic chemistry, fluorinated heterocyclic compounds have distinctively desirable properties suitable for use in pharmaceuticals and agrichemicals, especially their ability to penetrate the cell membrane barrier for drug absorption. Offering a needed overview of this relatively new addition to the heterocyclic family, this essential reference provides the latest state-of-the-art information on key application areas within fluorine chemistry. With contributions from experts from both industry and academia, the book covers the chemistry, synthesis, and applications of fluorinated heterocycles with chapters on: Three-, four-, five-, six-, and seven-membered fluorine-containing heterocycles Fluorinated nucleosides Fluorointermediates Applications of fluorinated heterocycles in agricultural products Pharmaceuticals containing fluorinated heterocycles Technical applications of fluorinated heterocycles Written by a team of world-recognized experts in the area of organic and industrial chemistry of fluorine, Fluorinated Heterocyclic Compounds: Synthesis, Chemistry, and Applications will prove valuable to both students and researchers from academia and industry seeking further knowledge of the synthetic methods, chemistry, and applications of major classes of fluorinated heterocycles.
Author: Valentine Nenajdenko Publisher: Springer ISBN: 3319044354 Category : Science Languages : en Pages : 769
Book Description
This two-volume work combines comprehensive information on the chemistry of the fluorinated heterocycles. The material has been divided such that the first volume is dedicated to 5-membered fluorinated heterocycles and macrocycles, while the second volume combines data connected with the chemistry of fluorine containing 6-membered heterocycles. Both volumes will be of interest to synthetic organic chemists in general, and particularly for those colleagues working in the fields of heterocyclic-compound chemistry, materials chemistry, medicinal chemistry, and fluorine chemistry. All information is presented and classified clearly to be effective source for broad auditory of chemists. It will be interesting for scientists working in the field of inorganic and coordination chemistry. Fluorinated heterocycles are becoming increasingly important in many areas including the pharmaceutical industry, materials science and agriculture. The presence of fluorine can result in substantial functional changes in the biological as well as physicochemical properties of organic compounds. Incorporation of fluorine into drug molecules can greatly affect their physicochemical properties, such as bond strength, lipophilicity, bioavailability, conformation, electrostatic potential, dipole moment, pKa etc. as well as pharmacokinetic properties, such as tissue distribution, rate of metabolism and pharmacological properties, such as pharmacodynamics and toxicology.
Author: American Chemical Society. Meeting Publisher: ISBN: Category : Language Arts & Disciplines Languages : en Pages : 390
Book Description
This is the first ACS symposium series book solely devoted to fluorinated heterocyclic compounds. Its contents encompasses all aspects of chemistry and applications of fluoroheterocycles including synthesis, biological activity, computational and medicinal research covering all major classes of heterocycles as well as popular fluorine-containing fragments.
Author: V Prakash Reddy Publisher: Newnes ISBN: 044453749X Category : Science Languages : en Pages : 331
Book Description
Organofluorine Compounds in Biology and Medicine covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area. - Covers the synthesis, biochemical, and therapeutic applications of organofluorine compounds - Offers a complete text on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways - Provides one of the first major reference books on the biological and medicinal applications of organofluorine chemistry
Author: Valentine Nenajdenko Publisher: Springer ISBN: 3319043463 Category : Science Languages : en Pages : 683
Book Description
This two-volume work combines comprehensive information on the chemistry of the fluorinated heterocycles. The material has been divided such that the first volume is dedicated to 5-membered fluorinated heterocycles and macrocycles, while the second volume combines data connected with the chemistry of fluorine containing 6-membered heterocycles. Both volumes will be of interest to synthetic organic chemists in general, and particularly for those colleagues working in the fields of heterocyclic-compound chemistry, materials chemistry, medicinal chemistry, and fluorine chemistry. All information is presented and classified clearly to be effective source for broad auditory of chemists. It will be interesting for scientists working in the field of inorganic and coordination chemistry. Fluorinated heterocycles are becoming increasingly important in many areas including the pharmaceutical industry, materials science and agriculture. The presence of fluorine can result in substantial functional changes in the biological as well as physicochemical properties of organic compounds. Incorporation of fluorine into drug molecules can greatly affect their physicochemical properties, such as bond strength, lipophilicity, bioavailability, conformation, electrostatic potential, dipole moment, pKa etc. as well as pharmacokinetic properties, such as tissue distribution, rate of metabolism and pharmacological properties, such as pharmacodynamics and toxicology.
Author: Angelo Albini Publisher: Routledge ISBN: 1351441027 Category : Science Languages : en Pages : 323
Book Description
This book provides a comprehensive presentation of all aspects of heterocyclic N-oxides. Topics discussed include the preparation of these compounds by N-oxidation of heterocycles and simultaneous synthesis of the ring and formation of the N-oxide group; general spectroscopic characteristics and molecular structure; and reactions and recently devel
Author: William R. Dolbier, Jr. Publisher: John Wiley & Sons ISBN: 1118831098 Category : Science Languages : en Pages : 418
Book Description
Following its well-received predecessor, this book offers an essential guide to chemists for understanding fluorine in spectroscopy. With over 1000 compounds and 100 spectra, the second edition adds new data – featuring fluorine effects on nitrogen NMR, chemical shifts, and coupling constants. • Explains how to successfully incorporate fluorine into target molecules and utilize fluorine substituents to structurally characterize organic compounds • Includes new data on nitrogen NMR, focusing on N-15, to portray the influence of fluorine upon nitrogen NMR chemical shifts and coupling constants • Expands on each chapter from the first edition with additional data and updated discussion from recent findings • "The flawless ordering of material covered in this stand-alone volume is such that information can be found very easily." – Angewandte Chemie review of the first edition, 2010
Author: Jinbo Hu Publisher: Springer ISBN: 9789811038952 Category : Science Languages : en Pages : 0
Book Description
This volume reviews the recent advances in formation of C-F bonds and X-F bonds (X = heteroatom) to produce useful fluorinated molecules for pharmaceuticals, materials and more. Reactions and methods associated with fluorination, including monofluorination, difluorination, trifluorination and other polyfluorination that have emerged within the past few years are systematically discussed. With contributions from front-line researchers in this field from both academia and industry, this book provides a valuable resource for scholars, graduate students as well as professionals.
Author: K. L. Ameta Publisher: Springer ISBN: 8132218507 Category : Science Languages : en Pages : 418
Book Description
The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc. The book also provides an insight of how green chemistry techniques are specific to the bioactive heterocyclic compounds.
Author: Al Postigo Publisher: Elsevier ISBN: 9780128129586 Category : Science Languages : en Pages : 0
Book Description
Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work.
Author: Viacheslav A. Petrov
Author: Viacheslav A. Petrov
Author: Valentine Nenajdenko
Author: American Chemical Society. Meeting
Author: V Prakash Reddy
Author: Valentine Nenajdenko
Author: Angelo Albini
Author: William R. Dolbier, Jr.
Author: Jinbo Hu
Author: K. L. Ameta
Author: Al Postigo