Author: Tatsuji NomuraPublisher: Fischer Gustav Verlag GmbH & Company KG
ISBN:
Category : Medical
Languages : en
Pages : 624
Book Description
The Potentialities and Limitations of the Nude Mouse
Author: Tatsuji NomuraPublisher: Fischer Gustav Verlag GmbH & Company KG
ISBN:
Category : Medical
Languages : en
Pages : 624
Book Description
The Nude Mouse in Oncology Research
Author: Epie BovenPublisher: CRC Press
ISBN: 1351094114
Category : Medical
Languages : en
Pages : 355
Book Description
The nude, athymic mouse (nu/nu) has become generally accepted as a valuable tool to study the biology and therapy of human cancers. This volume presents a critical review of the scientific merits of the animal as a recipient of human tumor tissue transplants. Important information is provided regarding biology, immunology, and measures for genetic and microbiological control of the nude mouse. The discussion of transplantation sites and transplantability of human tumor tissue to the animals includes both the description of host factors and the tumor type involved. The characterization and monitoring of xenografts is followed by a review on their possible application for studies in tumor biology, such as hormones, growth factors, drug resistance, tumor markers, and heterogeneity. Experimental therapy is dedicated to cytostatic agents, hormones, monoclonal antibodies, cytokines, differentiation inducers and radiotherapy. The book also provides critical remarks regarding the limitation of the nude-mouse tumor models. The Nude Mouse in Oncology Research will provide essential reference information for oncology researchers, researchers who work with the nude mouse on a regular basis, and pharmaceutical companies.
Journal of the National Cancer Institute
Author: Patient-Derived Mouse Models of Cancer
Author: Robert M. HoffmanPublisher: Springer
ISBN: 3319574248
Category : Medical
Languages : en
Pages : 304
Book Description
This text highlights seminal discoveries and also provides comprehensive and state-of the-art approach to mouse models of human patient tumors. These areas include training, basic techniques, as well as general troubleshooting. Subsequent chapters focus on the different mouse models of patient tumors including the various strains of immunodeficient mice currently available and the transplantation techniques that can be used as well as state-of-the-art imaging techniques. Practical applications of the models from drug discovery, genome analysis to personalized treatment are also covered. Written by experts in that field, each of these sections address these critical issues. A brief review of the existing literature addressing the particular topic follows in each section. Presently, there is no single source to provide information on technique and uses of mouse models of human patient tumors. Patient-Derived Mouse Models of Cancer will satisfy this need for cancer researchers, oncologists, pharmaceutical and biotechnology industry scientists as well as molecular biologists studying in vivo systems
Guide for the Care and Use of Laboratory Animals
Author: Publisher: National Academies
ISBN:
Category : Laboratory animals
Languages : en
Pages : 100
Book Description
Proceedings of the Third International Workshop on Nude Mice, Montana State University, Bozeman, Montana, September 6-9, 1979: Invited lectures, infection, and immunology
Author: Norman D. ReedPublisher: Fischer Gustav Verlag GmbH & Company KG
ISBN:
Category : Communicable diseases
Languages : en
Pages : 360
Book Description
The Potentialities and Limitations of the Nude Mouse
Author: Publisher:
ISBN: 9783437302725
Category : Immunological deficiency syndromes
Languages : en
Pages : 0
Book Description
Biotechnology: Potentials and Limitations
Author: S. SilverPublisher: Springer Science & Business Media
ISBN: 3642705359
Category : Science
Languages : en
Pages : 315
Book Description
hurdle will be in the latter area. The technological hurdles will be formi dable but will not limit what happens: once the basic ideas are available, the technology will be developed. The unique part of biotechnology will be to imagine what the possibilities are. There was a discussion in several of the groups on the problems of intro ducing a novel science into a social and economic context. What biotech nologists are learning on this matter is not novel, although that does not make it any less important or difficult. People in the development of elec tronics and computers, in the pharmaceutical industry, and in many other types of industry that have grown from university research have had to face these problems in the past. It is the old situation of having to reinvent the wheel again and again. There is one aspect on which biotechnology seems to have handled this inherent difficulty better than some of our predecessor technologies: the people in the biotechnology companies by and large take a rather academic approach to free communication with one another at meetings such as this and open publication of many of their basic findings in the literature. This seems unique and certainly is different from the experience of the recent Silicone Valley Industry, which in other ways tries to emulate an academic environment, but not in open and free publication.
Current Catalog
Author: National Library of Medicine (U.S.)Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1956
Book Description
Using Animals in Intramural Research
Author: Publisher:
ISBN:
Category : Animal experimentation
Languages : en
Pages : 308
Book Description