The Myostatin Project PDF Download

Author: G Robert Tait
Publisher: Xlibris Corporation
ISBN: 1499053819
Category : Fiction
Languages : en
Pages : 332

View

Book Description

Author: Eben Kirksey
Publisher: St. Martin's Press
ISBN: 1250265363
Category : Science
Languages : en
Pages : 214

View

Book Description
An anthropologist visits the frontiers of genetics, medicine, and technology to ask: Whose values are guiding gene editing experiments? And what does this new era of scientific inquiry mean for the future of the human species? "That rare kind of scholarship that is also a page-turner." —Britt Wray, author of Rise of the Necrofauna At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies—twin girls named Lulu and Nana—sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice." As scientists elsewhere start to catch up with China’s vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake: Who gets access to gene editing technologies? As countries loosen regulations around the globe, from the U.S. to Indonesia, can we shape research agendas to promote an ethical and fair society? Eben Kirksey takes us on a groundbreaking journey to meet the key scientists, lobbyists, and entrepreneurs who are bringing cutting-edge genetic engineering tools like CRISPR—created by Nobel Prize-winning biochemists Jennifer Doudna and Emmanuelle Charpentier—to your local clinic. He also ventures beyond the scientific echo chamber, talking to disabled scholars, doctors, hackers, chronically-ill patients, and activists who have alternative visions of a genetically modified future for humanity. The Mutant Project empowers us to ask the right questions, uncover the truth, and navigate this brave new world.

Author: Kirksey, Eben
Publisher: Policy Press
ISBN: 152921730X
Category : Social Science
Languages : en
Pages : 362

View

Book Description
Longlisted for the Baillie Gifford Prize 2021 An anthropologist visits the frontiers of genetics, medicine, and technology to ask: whose values are guiding gene-editing experiments, and what are the implications for humanity? At a conference in Hong Kong in November 2018, Dr. Jiankui He announced that he had created the first genetically modified babies—twin girls named Lulu and Nana—sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for “illegal medical practice.” As scientists elsewhere start to catch up with China’s vast genetic research programme, gene editing is fuelling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake. Who gets access to gene-editing technologies? As countries loosen regulations around the globe, can we shape research agendas to promote an ethical and fair society? Professor Eben Kirksey takes us on a groundbreaking journey to meet the key scientists, lobbyists, and entrepreneurs who are bringing cutting-edge genetic modification tools like CRISPR to your local clinic. He also ventures beyond the scientific echo chamber, talking to doctors, hackers, chronically ill patients, disabled scholars, and activists and who have alternative visions of a genetically modified future for humanity. The Mutant Project empowers us to ask the right questions, uncover the truth, and navigate this new era of scientific enquiry.

Author: E. Paul Zehr
Publisher: ECW Press
ISBN: 1770905901
Category : Juvenile Fiction
Languages : en
Pages : 247

View

Book Description
Superheroes, science, and one ordinary girl's quest for greatness. Join 13-year-old Jessie as she keeps a diary of her class's yearlong research project on superheroes, which culminates in the Superhero Slam: a head-to-head debate battle! It's shy, comics-obsessed Jessie's dream come true . . . and worst nightmare. She decides to champion Batgirl, a regular person (albeit with major talent and training under her utility belt), and soon Jessie wonders what it would take to be Batgirl. Will she prove to her best friends, Cade and Audrey, that she's more than a sidekick? Can she take down archenemy Dylan at the Slam? Combining science facts, lively illustrations, and comic-book trivia with actual correspondence from superhumans such as NYPD Sergeant Mike Bruen, Olympian Clara Hughes, and Captain Marvel writer Kelly Sue DeConnick, Project Superhero is a celebration of the heroes among us and of one girl's super-secret identity: herself.

Author: Zoe Davies
Publisher: John Wiley & Sons
ISBN: 111874117X
Category : Medical
Languages : en
Pages : 481

View

Book Description
From genetics to functional anatomy, cell biology to the equine digestive system, Equine Science, Third Edition covers all the essential scientific knowledge you need for your equine programme. Thoroughly updated, this new edition features a clear, systematic presentation, stunning full-colour photographs and illustrations, chapter summary points and self-assessment questions throughout. Describes the structure and function of the various body systems of the horse Explains the scientific rationale behind modern equine training practices Features new chapters on exercise physiology and the evolution of the horse Reflects the latest scientific advances and changes in the student curriculum Includes new information on circadian rhythms and sleep patterns, the immune system, and hindgut microbiology. A powerful teaching and learning aid, Equine Science, Third Edition is an essential text for students on higher education equine studies and equine science programmes, as well as those studying for BHS qualifications up to BHSII Stage 4 Horse Knowledge and Care.

Author: Katherine Paris
Publisher: Springer Nature
ISBN: 3031218205
Category : Science
Languages : en
Pages : 281

View

Book Description
This monograph introduces current genome editing technologies—clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated (Cas) systems, transcription activator-like effector nucleases (TALENs), and zinc-finger nucleases (ZFNs)—and provides an assessment of the risk of misuse of these technologies based on the following parameters: accessibility, ease of misuse, magnitude of potential harm, and imminence of potential misuse. The findings from this assessment are applied to analyze and evaluate the threat posed by the intentional misuse of genome editing technologies to develop biological weapons. Furthermore, the book discusses the implications of misuse for different applications of genome editing, such as making existing pathogens more dangerous, modifying the human microbiome, weaponizing gene drives, engineering super soldiers, and augmenting the general population to confer economic advantages. Technologies that enable genome editing with programmable nucleases—including CRISPR, TALEN, and ZFN—allow for the precise genetic modification of organisms and cultured cells. While these technologies are used for a variety of beneficial applications, intelligence and defense experts have raised concerns that genome editing technologies, especially CRISPR, could be misused to develop new and improved biological weapons. Furthermore, experts worry that the number and type of actors who could potentially misuse genome editing is dramatically increasing given the democratization of biology, which is allowing biology to become more accessible to everyone including nonexperts. The book provides a comprehensive assessment of how feasible it is for users with different levels of knowledge and skill to acquire and then to apply the technologies to develop a biological weapon. It also provides an assessment of governability and a tailored set of recommendations that address security concerns. These recommendations are sensitive to the cost-benefit trade-off of regulating genome editing technologies. The book targets researchers as well as intelligence analysts, defense and security personnel, and policymakers.

Author:
Publisher: Birkhäuser
ISBN: 3034883919
Category : Medical
Languages : en
Pages : 314

View

Book Description
S. Ren and E.J. Lien: CaCo-2 cell permeability vs human gastrointestinal absorption: QSPR analysis.- J.C.G. Halford and J.E. Blundell: Pharmacology of appetite suppression.- B. Olivier, W. Soudijn and I. van Wijngaarden: Serotonin, dopamine and norepinephrine transporters in the central nervous system and their inhibitors.- D. Poyner, H. Cox, M. Bushfield, J.M. Treherne and M.K. Demetrikopoulos: Neuropeptides in drug research.- M. Kumari and M.K. Ticku: Regulation of NMDA receptors by ethanol.- H. Horikoshi, T. Hashimoto and T. Fujiwara: Troglitazone and emerging glitazones: new avenues for potential therapeutic benefits beyond glycemic control.- Rosamund C. Smith and Simon J. Rhodes: Applications of developmental biology to medicine and animal agriculture.

Author: M. F. W. te Pas
Publisher: Cabi
ISBN: 9780851998114
Category : Medical
Languages : en
Pages : 411

View

Book Description
Number and size of muscle fibres in relation to meat production. Fibre type identification and functional characterization in adult livestock animals. Manipulation of muscle fibre number during prenatal development. The effect of growth and exercise on muscle characteristics in relation to meat quality. Nutrition, hormone receptor expression and gene interactions: implications for development and disease. The impact of minerals and micronutrients on growth control. Na+ K+-ATPase in skeletal muscle: significance of exercise and thyroid hormones for development and performance. local and ystemic regulation of muscle growth. Proteolytic systems and the regulation of muscle remodelling and breakdown. Themuscle regulatory factors gene family in relation to meat production.The muscle transcriptome. Genome analysis of QTL for muscle tissue development and meat quality. Functional genomics and proteomics in relation to muscle tissue. Role of myostatin in muscle growth. The callipyge mutation for sheep muscular hypertrophy genetics, physiology and meat quality. Genetic control of intramuscular fat accretion, Post-mortem muscle proteolysis and meat tenderness.Water-holding capacity of meat.

Author: Lee Tang
Publisher: LMT Press
ISBN: 0995943168
Category : Business & Economics
Languages : en
Pages : 90

View

Book Description
Power and Peril of Gene Editing CRISPR/Cas9 Technology This book is a summary of “A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution” by Jennifer A. Doudna and Samuel H. Sternberg. This book tells the story of CRISPR and “gene-editing.” CRISPR is a cutting-edge gene-editing technology that mimics what happens naturally in bacteria. It enables scientists to “play god” with plant or animal DNA, with unlimited power and peril. The technology of gene editing is the most important advance in our era. The possibility of forever altering the genetic composition of humankind is frightening. Yet we can’t overlook the opportunities that may lead to inventions for cures of HIV, debilitating genetic diseases, and cancers, and end food shortages. The book will demystify this exciting area of science and inspire you to seek answers to tough moral and ethical questions on the use of this technology. Read this book and get involved in the debate on the moral and ethical issues on the use of this technology. This guide includes: * Book Summary—helps you understand the key concepts. * Online Videos—cover the concepts in more depth. Value-added from this guide: * Save time * Understand key concepts * Expand your knowledge

Author: Katrin Gerlinger
Publisher: BoD – Books on Demand
ISBN: 3732287858
Category : Political Science
Languages : en
Pages : 158

View

Book Description
Just like a phantom, the topic of »gene doping« keeps haunting the debates regarding the future of competitive sports for years. Very often, corresponding fantasies and visions culminate in the imagination of super athletes who are permanently manipulated with regard to their genetic disposition. However, the application scenarios to be expected will be far more unspectacular, but more probable and more obvious at the same time. Very soon, we will have to expect the use of new substances as well as of methods in gene and cell therapy for targeted manipulation of gene activity. Their use promises a highly efficient performance enhancement and will be difficult to prove, if at all. This book provides comprehensive answers to the key questions of the further development: Which scientific results could cater to the needs of potential gene doping? Where are the future gateways in top-level and popular sports? And how can prohibitions and monitoring be used in responding to this? Another question will be which individual behavioural patterns of athletes and which social contexts will play a role with regard to the potential »career« of gene doping.