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Author: National Academies of Sciences, Engineering, and Medicine Publisher: National Academies Press ISBN: 0309459575 Category : Medical Languages : en Pages : 483
Book Description
Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Author: National Academies of Sciences, Engineering, and Medicine Publisher: National Academies Press ISBN: 0309459575 Category : Medical Languages : en Pages : 483
Book Description
Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Author: Robert Vink Publisher: University of Adelaide Press ISBN: 0987073052 Category : Medical Languages : en Pages : 354
Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author: Adam Bisaga Publisher: The Experiment ISBN: 1615194584 Category : Self-Help Languages : en Pages : 302
Book Description
From a leading addiction expert, a desperately needed medical guide to understanding, treating, and finally defeating opioid use disorder Drug overdoses are now the leading cause of death for Americans under the age of 50, claiming more lives than the AIDs epidemic did at its peak. Opioid abuse accounts for two-thirds of these overdoses, with over 100 Americans dying from opioid overdoses every day. Now Overcoming Opioid Addiction provides a comprehensive medical guide for opioid use disorder (OUD) sufferers, their loved ones, clinicians, and other professionals. Here is expertly presented, urgently needed information and guidance, including: Why treating OUD is unlike treating any other form of drug dependency The science that underlies addiction to opioids, and a clear analysis of why this epidemic has become so deadly The different stages and effective methods of treatment, including detoxification vs. maintenance medications, as well as behavioral therapies How to deal with relapses and how to thrive despite OUD Plus a chapter tailored to families with crucial, potentially life-saving information, such as how to select the best treatment program, manage medications, and reverse an overdose.
Author: David T. Courtwright Publisher: ISBN: Category : History Languages : en Pages : 296
Book Description
What drives the drug trade, and how has it come to be what it is today? A global history of the acquisition of progressively more potent means of altering ordinary waking consciousness, this book is the first to provide the big picture of the discovery, interchange, and exploitation of the planet’s psychoactive resources, from tea and kola to opiates and amphetamines.
Author: Mikhail Afanasevich Bulgakov Publisher: New Directions Publishing ISBN: 0811221695 Category : Fiction Languages : en Pages : 65
Book Description
From the author of The Master and Margarita comes this short and tragic masterpiece about drug addiction Young Dr. Bromgard has come to a small country town to assume a new practice. No sooner has he arrived than he receives word that a colleague, Dr. Polyakov, has fallen gravely ill. Before Bromgard can go to his friend’s aid, Polyakov is brought to his practice in the middle of the night with a self-inflicted gunshot wound, and, barely conscious, gives Bromgard his journal before dying. What Bromgard uncovers in the entries is Polyakov’s uncontrollable and merciless descent into morphine addiction — his first injection to ease his back pain, the thrill of the drug as it overtakes him, the looming signs of addiction, and the feverish final entries before his death.
Author: David F. Musto Publisher: Oxford University Press, USA ISBN: 0195125096 Category : Medical Languages : en Pages : 431
Book Description
The American Disease is a classic study of the development of drug laws in the United States. Supporting the theory that Americans' attitudes toward drugs have followed a cyclic pattern of tolerance and restraint, author David F. Musto examines the relationz between public outcry and the creation of prohibitive drug laws from the end of the Civil War up to the present. Originally published in 1973, and then in an expanded edition in 1987, this third edition contains a new chapter and preface that both address the renewed debate on policy and drug legislation from the end of the Reagan administration to the current Clinton administration. Here, Musto thoroughly investigates how our nation has dealt with such issues as the controversies over prevention programs and mandatory minimum sentencing, the catastrophe of the crack epidemic, the fear of a heroin revival, and the continued debate over the legalization of marijuana.
Author: Steven Martin Publisher: Villard ISBN: 0345517857 Category : Biography & Autobiography Languages : en Pages : 417
Book Description
NEW YORK TIMES BESTSELLER A renowned authority on the secret world of opium recounts his descent into ruinous obsession with one of the world’s oldest and most seductive drugs, in this harrowing memoir of addiction and recovery. A natural-born collector with a nose for exotic adventure, San Diego–born Steven Martin followed his bliss to Southeast Asia, where he found work as a freelance journalist. While researching an article about the vanishing culture of opium smoking, he was inspired to begin collecting rare nineteenth-century opium-smoking equipment. Over time, he amassed a valuable assortment of exquisite pipes, antique lamps, and other opium-related accessories—and began putting it all to use by smoking an extremely potent form of the drug called chandu. But what started out as recreational use grew into a thirty-pipe-a-day habit that consumed Martin’s every waking hour, left him incapable of work, and exacted a frightful physical and financial toll. In passages that will send a chill up the spine of anyone who has ever lived in the shadow of substance abuse, Martin chronicles his efforts to control and then conquer his addiction—from quitting cold turkey to taking “the cure” at a Buddhist monastery in the Thai countryside. At once a powerful personal story and a fascinating historical survey, Opium Fiend brims with anecdotes and lore surrounding the drug that some have called the methamphetamine of the nineteenth-century. It recalls the heyday of opium smoking in the United States and Europe and takes us inside the befogged opium dens of China, Thailand, Vietnam, and Laos. The drug’s beguiling effects are described in vivid detail—as are the excruciating pains of withdrawal—and there are intoxicating tales of pipes shared with an eclectic collection of opium aficionados, from Dutch dilettantes to hard-core addicts to world-weary foreign correspondents. A compelling tale of one man’s transformation from respected scholar to hapless drug slave, Opium Fiend puts us under opium’s spell alongside its protagonist, allowing contemporary readers to experience anew the insidious allure of a diabolical vice that the world has all but forgotten.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309175380 Category : Medical Languages : en Pages : 329
Book Description
Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.
Author: National Academies of Sciences, Engineering, and Medicine
Author: National Academies of Sciences, Engineering, and Medicine
Author: Robert Vink
Author: Thomas de Quincey
Author: Adam Bisaga
Author: David T. Courtwright
Author: Mikhail Afanasevich Bulgakov
Author: 
Author: David F. Musto
Author: Steven Martin
Author: Institute of Medicine