The Metals of Life PDF Download

Author: David Raymond Williams
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 186

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Author: David R. Williams
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Author: Astrid Sigel
Publisher: Springer
ISBN: 3319217569
Category : Science
Languages : en
Pages : 663

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MILS-16 provides an up-to-date review of the impact of alkali metal ions on life. Their bioinorganic chemistry and analytical determination, the solid state structures of bio-ligand complexes and the properties of alkali metal ions in solution in the context of all kinds of biologically relevant ligands are covered, this includes proteins (enzymes) and nucleic acids (G-quadruplexes). Minerals containing sodium (Na+) and potassium (K+) are abundant in the Earth's crust, making Na+ and K+ easily available. In contrast, the alkali elements lithium (Li+), rubidium, and cesium are rare and the radioactive francium occurs only in traces. Since the intra- and extracellular, as well as the compartmental concentrations of Na+ and K+ differ significantly, homeostasis and active transport of these ions are important; this involves transporters/carriers and pore-forming ion channel proteins. Systems like Na+/K+-ATPases, H+/K+-ATPases or Na+/H+ antiporters are thoroughly discussed. The role of K+ in photosynthesis and the role of Na+ in charging the "battery of life" are pointed out. Also, the relationships between alkali metal ions and diseases (e.g., Parkinson or traumatic brain injury) are covered and the relevance of Li+ salts in medicine (pharmacology and mechanism) is reviewed. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 16, The Alkali Metal Ions: Their Role for Life, which are written by 44 internationally recognized experts from 12 nations. The impact of this vibrant research area is manifested in nearly 3000 references, over 30 tables and more than 150 illustrations (two thirds in color). MILS-16 also provides excellent information for teaching. Astrid Sigel, Helmut Sigel, and Roland K. O. Sigel have long-standing interests in Biological Inorganic Chemistry. Their research focuses on metal ion interactions with nucleotides and nucleic acids and on related topics. They edited previously 44 volumes in the series Metal Ions in Biological Systems.

Author: Helmut Sigel
Publisher: CRC Press
ISBN: 9780824786397
Category : Science
Languages : en
Pages : 610

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Continuing to explore the relationship between the chemistry of metals and life processes, this volume in the Metal Ions in Biological Systems series examines the degradation of environmental pollutants by micro-organisms. It covers the action of micro-organisms and metalloenzymes on lignin, tannins, hemicelluloses, cellulose and aromatic compounds, as well as on halogenated aromatics and aliphatics; analyzes mechanistic aspects; considers the role of metalloproteases in biotechnology and wastewater sludge treatment; and describes the metal-dependent conversion of inorganic nitrogen and sulfur compounds.

Author: Jonathan Black
Publisher: CRC Press
ISBN: 9780849339592
Category : Medical
Languages : en
Pages : 526

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Bioengineers need a thorough grounding in biocompatibility - the biological performance of materials. Until now, there were no publications suitable for a neophyte in the field; prior publications were either not comprehensive or focused on rather narrow interests. Drawing on the author's 35 years of experience as a teacher, researcher, and consultant in biomaterials science and engineering (BSE), Biological Performance of Materials: Fundamentals of Biocompatibility, Fourth Edition focuses primarily on principles of biological performance at a relatively fundamental level, analyzing interactions between living organisms and nonliving materials used in medical devices - the subject that sets BSE apart as a distinct field of investigation. Following an introductory section, the book is divided into three sections: the material response to biological systems, host response to biomaterials, and test methods for determining biological response in vitro as well as in animal models and clinical settings. Supplemental "Interparts" summarize the physical properties of commonly used metallic, polymeric, and ceramic biomaterials. They also provide a guide to understanding the clinical performance of implanted biomaterials.

Author: United States. Environmental Protection Agency. Library Systems Branch
Publisher:
ISBN:
Category : Environmental protection
Languages : en
Pages : 490

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Author: United States. Environmental Protection Agency. Library Systems Branch
Publisher:
ISBN:
Category : Environmental protection
Languages : en
Pages : 702

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Author: Colin Suckling
Publisher: Springer Science & Business Media
ISBN: 9400918321
Category : Science
Languages : en
Pages : 394

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As the first edition of this book was going through the publication process, a revolution was taking place in the technologies available for the study of enzymes. The techniques of molecular biology, especially in genetic engineering of organisms and in site specific mutagenesis of genes, were established and were being brought into use to solve many problems in in enzymology. Added to these fundamental and applied science, not least advances the possibility of generating catalysts from antibodies has become a topic of major interest. These major innovations have changed the emphasis of much bioorganic research; whereas in the past, the protein was often the 'sleeping partner' ina study, its detailed function is now the major focus of scientific interest. Similarly in industry, the potential of genetically manipulated organisms to satisfy the needs for the production of chemicals and foodstuffs has been widely recognised. The second edition of 'Enzyme Chemistry, Impact and Applications' takes on board these new develop ments whilst maintaining the overall aims and views of the first edition. Many of the chapters have been completely rewritten to take account of advances in the last five years especially with regard to the impact of biologically based technologies. Although the book continues to approach its subject matter from the point of view of the chemist, the increased interdisciplinary content of much modern science will be obvious from the discussion.

Author: Raul Sutton
Publisher: CRC Press
ISBN: 1420069365
Category : Medical
Languages : en
Pages : 282

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Presents short topics tied to numerical or conceptual ideas, reinforced with worked examples and questions Retaining the user-friendly style of the first edition, this text is designed to eliminate the knowledge gap for those life sciences students who have not studied chemistry at an advanced level. It contains new chapters on -

Author: Erich Konigsberger
Publisher: John Wiley & Sons
ISBN: 0470092114
Category : Science
Languages : en
Pages : 302

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This title takes an interdisciplinary approach to the central role of solubility in pathological biomineralisation, ranging from traditional thermodynamics and kinetics to unusual concepts such as the PILP process. The scientific background and expertise of the contributors, ranges accordingly from solubility modelling and database development, renal stone and bone implant research, Mössbauer spectroscopy and structural chemistry to biochemistry and crystallisation. The chapters all have a quantitative, physico-chemical component rather than giving purely phenomenological descriptions. The contributors deal with aspects and concepts that have not previously been common in the study of pathological biomineralisation processes.