Lymphatic Structure and Function in Health and Disease PDF Download

Author: Felicity N.E. Gavins
Publisher: Academic Press
ISBN: 0128156465
Category : Medical
Languages : en
Pages : 180

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Book Description
Lymphatic Structure and Function in Health and Disease serves as a resource book on what has been learned about lymphatic structure, function and anatomy within different organ systems. This is the first book to bring together lymphatic medicine as a whole, with in-depth analysis of specific aspects of lymphatics in different vascular pathologies. This book is a useful tool for scientists, practicing clinicians and residents, in particular, those in vascular biology, neurology, cardiology and general medicine. Chapters discuss topics such as ontogeny and phylogeny of lymphatics, lymphatic pumping, CNS lymphatics, lymphatics in transplant and lymphatic reconstruction. Brings together lymphatic medicine as a whole, with an in-depth analysis of the specific basic science aspects of lymphatic structure and function Covers the clinical aspects of lymphatics in different vascular pathologies Co-published with the International Society of Neurovascular Diseases Discusses lymphatic structure and function in all of the major organ systems

Author: J. Winny Yun
Publisher: Biota Publishing
ISBN: 1615047921
Category : Science
Languages : en
Pages : 106

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Book Description
The lymphatic system develops and functions in parallel with the blood circulatory system (termed the "hemovasculature") and accomplishes transport of interstitial fluids, dietary lipids, and reverse transport of cholesterol, immune cells, and antigens—providing a critical homeostatic fluid balance and transmission of immune cells and mediators back to the cardiovascular system. Although the daily flow of lymph (normally 1-2 L/day under unstressed conditions) is far lower than that of daily blood flow (which is 7,500 L/day), without the adequate functioning of the lymphatics, virtually all organs and tissues would acutely suffer many different physical and inflammatory stresses ranging from edema to organ system failure. Although blood and lymphatic vessels often form in anatomic parallels to one another, our knowledge of the workings of the lymphatic system, the fine structure of lymphatic networks, how they function in different organs, and how they are regulated physiologically and immunologically are far from parallel; our knowledge of the lymphatic system still remains at only a tiny fraction of what is understood about the cardiovascular system. Although both the cardiovascular and lymphatic systems are important transport systems, what they transport and how they transport and propel these very different cargoes could not be more dissimilar. This book provides an overview of the history of the discovery (and re-discovery) of the components of the lymphatic system, lymphatic anatomy, physiological functions of lymphatics, molecular features of the lymphatic system, and clinical perspectives involving lymphatics which may be of interest to scientists, clinicians, patients, and the lay public. We provide a current understanding of some of the more important structural similarities and differences between lymphatics and the blood vascular system, their coordinated control by angiogenic and hemangiogenic growth factors and other modulators, the fate and lineage determinants which control lymphatic development, and the roles that lymphatics may play in several different diseases.

Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 0470319429
Category : Science
Languages : en
Pages : 260

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Book Description
The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a common set of molecules and processes that are conserved throughout vertebrate embryogenesis while, in addition, highlighting aspects that may differ between different animal groups. The discovery in the past decade of the crucial role of new blood vessel formation for the development of cancers has generated great interest in angiogenesis (the formation of new blood vessels from pre-existing ones), with its major implications for potential cancer-control strategies. In addition, there are numerous situations where therapeutic treatments either require or would be assisted by vasculogenesis (the de novo formation of blood vessels). In particular, post-stroke therapies could include treatments that stimulate neovascularization of the affected tissues. The development of such treatments, however, requires thoroughly understanding the developmental properties of endothelial cells and the basic biology of blood vessel formation. While there are many books on angiogenesis, this unique book focuses on exactly this basic biology and explores blood vessel formation in connection with tissue development in a range of animal models. It includes detailed discussions of relevant cell biology, genetics and embryogenesis of blood vessel formation and presents insights into the cross-talk between developing blood vessels and other tissues. With contributions from vascular biologists, cell biologists and developmental biologists, a comprehensive and highly interdisciplinary volume is the outcome.

Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :

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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Author: D. W. Molander
Publisher: Springer Science & Business Media
ISBN: 1461251982
Category : Medical
Languages : en
Pages : 357

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Book Description
This volume presents a practical approach for clinicians who work with patients afflicted with diseases of the lymphoid system and bone marrow. Associated biochemical, hematological, and chromosomal abnormalities, as well as infectious complications, are covered because of their importance in managing patients with lymphatic diseases. In addition, cell kinetics and the classification of lym phocytic lymphomas are included because familiarity with these subjects leads to a better understanding of the physiology of the disease. Radiological techniques that aid the clinician in the diagnosis and management of diseases of the lymphoid tissue are discussed. The explosive interest in patients with generalized acquired (auto) immune deficiency syndrome (AIDS) prompted the inclusion of a chapter exclusively devoted to this topic. Finally, the chapter dealing with psychological aspects of patients with cancer allows the reader to become familiar with useful techniques. Distilled from a vast array of data and representing the most up-to-date material available, this volume is intended to be of interest to internists, oncolo gists, hematologists, radiotherapists, nurses, and anyone in an associated pa ramedical field who may be involved in the care of patients with diseases of the lymphatic system. Acknowledgements: I am indebted to the following for their help in making this volume possible: Mr. Rudy De Angelo and the Hudson County Chapter of the Pack Medical Foundation, Mrs. Louis Berkoff, Mrs. Frances Goldman, The Pack Medical Foundation, Mr. and Mrs. Julius Schure and Mr. Richard Schure. DAVID W. MOLANDER, M.D.

Author: Joshua Scallan
Publisher: Morgan & Claypool Publishers
ISBN: 1615040668
Category : Science
Languages : en
Pages : 86

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Book Description
The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the extracellular matrix and lymphatics. In addition to its role in the regulation of vascular volume, transcapillary fluid filtration also allows for continuous turnover of water bathing tissue cells, providing the medium for diffusional flux of oxygen and nutrients required for cellular metabolism and removal of metabolic byproducts. Transendothelial volume flow has also been shown to influence vascular smooth muscle tone in arterioles, hydraulic conductivity in capillaries, and neutrophil transmigration across postcapillary venules, while the flow of this filtrate through the interstitial spaces functions to modify the activities of parenchymal, resident tissue, and metastasizing tumor cells. Likewise, the flow of lymph, which is driven by capillary filtration, is important for the transport of immune and tumor cells, antigen delivery to lymph nodes, and for return of filtered fluid and extravasated proteins to the blood. Given this background, the aims of this treatise are to summarize our current understanding of the factors involved in the regulation of transcapillary fluid movement, how fluid movements across the endothelial barrier and through the interstitium and lymphatic vessels influence cell function and behavior, and the pathophysiology of edema formation. Table of Contents: Fluid Movement Across the Endothelial Barrier / The Interstitium / The Lymphatic Vasculature / Pathophysiology of Edema Formation

Author: Gerald M Lemole
Publisher: Hachette UK
ISBN: 1472293983
Category : Medical
Languages : en
Pages : 240

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Book Description
The lymphatic system has been one of the most misunderstood systems in our bodies. Until now. Cardiothoracic surgeon Dr. Gerald M. Lemole explains why a healthy lymphatic flow aids our bodies in reducing toxins that contribute to disease and injury. In ten short chapters, Dr. Lemole demystifies the lymphatic system, describes how powerful it is and shows how to maintain a healthy lymph system to combat specific diseases and health problems - from heart disease to cognitive function to weight management. Featuring sidebars with charts and graphs that illustrate basic principles, Lymph & Longevity also includes menus, recipes and information on supplements, as well as basic yoga and meditation guides. Illuminating, informative, and practical this essential guide is timelier now than ever as we continue to work to protect ourselves and our communities against COVID-19 and other viruses.

Author: Norman Browse
Publisher: CRC Press
ISBN: 9780340762035
Category : Medical
Languages : en
Pages : 416

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Book Description
This comprehensive and authoritative book covers the basic science aspects of the lymphatic system and the pathophysiology of its diseases. The major part covers treatment options, uniquely combining both surgical and non-invasive therapeutic approaches. Authored by three leading authorities in the study of lymphatic disease this text has specialist contributions from other international experts.

Author: Robert Dieter
Publisher: McGraw-Hill Education / Medical
ISBN: 9780071601580
Category : Medical
Languages : en
Pages : 688

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Book Description
The definitive overview of venous and lymphatic diseases—complete with 400 color images 5 STAR DOODY'S REVIEW! "This is a valuable resource for any physician taking care of patients with venous and/or lymphatic disorders. It is an up-to-date, comprehensive book on the diagnosis and treatment of patients with these often under-recognized disorders. Well written, with many high quality illustrations, figures, and tables, this book will serve as an important reference for many students and practitioners in a variety of specialties."--Doody's Review Service Presented in full color and written by a world-renowned author team, this all-in-one guide covers every key aspect of disorders affecting the venous and lymphatic systems. Venous and Lymphatic Diseases opens with fundamental topics, including anatomy and physiology, which provide a solid foundation for such important clinical considerations as the physical examination and appropriate diagnostic imaging modalities, specific disease states, and treatment protocols. You’ll also find incisive overviews of conditions commonly encountered in clinical practice, which are conveniently presented by body system. Supported by numerous references and color illustrations throughout, Venous and Lymphatic Diseases expertly reviews the latest advances in the field and takes you through new and emerging treatment options, including pharmacologic therapies. Features: All inclusive coverage of everything from common disorders, such as varicose veins, to unusual and rare entities, including trauma and congenital abnormalities Up-to-date information on function and dysfunction, plus proven strategies that facilitate accurate diagnosis and successful therapeutic outcomes An important, timely section on systemic diseases that includes coverage of tumors, malignancy, and venous hypertension resulting from chronic heart failure A concluding section offers a practical overview of lymphatics, the clinical approach to the patient with edema, and wound care More than 400 superb, full-color images, including clear, precise illustrations, photographs, and radiographs--as well as numerous tables and figures--in every chapter, reinforcing the text’s authoritative content Excellent pedagogy, including reader-friendly chapter introductions, chapter-ending summaries, and full references to facilitate understanding and review

Author: Andreas Bikfalvi
Publisher: Springer
ISBN: 3319743767
Category : Medical
Languages : en
Pages : 192

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Book Description
This book provides a comprehensive account of vascular biology and pathology and its significance for health and disease. It systematically and chronologically explains how we came to our current understanding of the vasculature and it ́s function today, and describes in an entertaining way the diverse flaws and turns in science and medicine from the past. It thereby offers a complete and well-studied history on vascular biology and medicine. The book has an easy-to-read style and is written for students as well as scientists, physicians and lecturers in the field of biomedicine, human physiology, cardiology and hematology.