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The Evolutionary Roots of Human Brain Diseases

The Evolutionary Roots of Human Brain Diseases PDF Author: Nico J. Diederich
Publisher: Oxford University Press
ISBN: 0197676596
Category : Medical
Languages : en
Pages : 577

Book Description
"Traditionally, studies and textbooks in Neurology or Psychiatry, as well as allied disciplines, deal with proximate causes of diseases and therapies, but remain mute or minimally interested in their ultimate causes including the phylogeny and adaptive significance of disease manifestations. Yet, as clinicians or basic researchers, we are conscious of potential evolutionary roots of neurological and psychiatric symptoms, often offering a rudimentary explanation but never delving deeply into the current role of evolutionary science as it relates to health and disease. We may miss appreciation of the role of adaptive properties, evolutionarily based neuronal circuitries, unbalanced cellular energy demands, and the potential health consequences of residual syndromic behaviors that were possibly useful in early times of human development, but presently are obsolete and pathological. The problem is amplified, because there is often no interdisciplinary dialogue between anthropology and evolutionary biology on one side and clinical sciences on the other side. However, the evolutionary tracing back of disease pathways may disclose unexpected insights and trigger the design of innovative research as well as propel the development of new therapeutic interventions. There could also be a better apprehension of compensatory behaviors, both at the cellular level as well as the systemic the behavioural levels, that could be the expected fruits of such collaborations. So far scientists fall short in modeling the complexity of human (social) life, human language, or manual dexterity, and mental or emotional behaviors that typify human neurological or psychological function and dysfunction. Finally, there remain obstacles in the form of poor animal modeling for human brain diseases and for human longevity. The present book aims to fill these gaps by presenting an evolutionary view of neurological and psychiatric conditions that is meant to complement and enrich existing medical perspectives"--

The Evolutionary Roots of Human Brain Diseases

The Evolutionary Roots of Human Brain Diseases PDF Author: Nico J. Diederich
Publisher: Oxford University Press
ISBN: 0197676596
Category : Medical
Languages : en
Pages : 577

Book Description
"Traditionally, studies and textbooks in Neurology or Psychiatry, as well as allied disciplines, deal with proximate causes of diseases and therapies, but remain mute or minimally interested in their ultimate causes including the phylogeny and adaptive significance of disease manifestations. Yet, as clinicians or basic researchers, we are conscious of potential evolutionary roots of neurological and psychiatric symptoms, often offering a rudimentary explanation but never delving deeply into the current role of evolutionary science as it relates to health and disease. We may miss appreciation of the role of adaptive properties, evolutionarily based neuronal circuitries, unbalanced cellular energy demands, and the potential health consequences of residual syndromic behaviors that were possibly useful in early times of human development, but presently are obsolete and pathological. The problem is amplified, because there is often no interdisciplinary dialogue between anthropology and evolutionary biology on one side and clinical sciences on the other side. However, the evolutionary tracing back of disease pathways may disclose unexpected insights and trigger the design of innovative research as well as propel the development of new therapeutic interventions. There could also be a better apprehension of compensatory behaviors, both at the cellular level as well as the systemic the behavioural levels, that could be the expected fruits of such collaborations. So far scientists fall short in modeling the complexity of human (social) life, human language, or manual dexterity, and mental or emotional behaviors that typify human neurological or psychological function and dysfunction. Finally, there remain obstacles in the form of poor animal modeling for human brain diseases and for human longevity. The present book aims to fill these gaps by presenting an evolutionary view of neurological and psychiatric conditions that is meant to complement and enrich existing medical perspectives"--

Human Evolution Beyond Biology and Culture

Human Evolution Beyond Biology and Culture PDF Author: Jeroen C. J. M. van den Bergh
Publisher: Cambridge University Press
ISBN: 1108470971
Category : Nature
Languages : en
Pages : 575

Book Description
A complete account of evolutionary thought in the social, environmental and policy sciences, creating bridges with biology.

Textbook of Evolutionary Psychiatry and Psychosomatic Medicine

Textbook of Evolutionary Psychiatry and Psychosomatic Medicine PDF Author: Martin Brüne
Publisher: Oxford University Press
ISBN: 0198717946
Category : Medical
Languages : en
Pages : 485

Book Description
This book is unique in taking an evolutionary perspective to understanding psychiatric and psychosomatic conditions. It explores how the human brain/mind has been shaped by natural and sexual selection and why adaptations to environmental conditions in our evolutionary past may not always work in our best interests.

The Story of the Human Body

The Story of the Human Body PDF Author: Daniel Lieberman
Publisher: Vintage
ISBN: 030774180X
Category : Science
Languages : en
Pages : 482

Book Description
A landmark book of popular science that gives us a lucid and engaging account of how the human body evolved over millions of years—with charts and line drawings throughout. “Fascinating.... A readable introduction to the whole field and great on the making of our physicality.”—Nature In this book, Daniel E. Lieberman illuminates the major transformations that contributed to key adaptations to the body: the rise of bipedalism; the shift to a non-fruit-based diet; the advent of hunting and gathering; and how cultural changes like the Agricultural and Industrial Revolutions have impacted us physically. He shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning a paradox: greater longevity but increased chronic disease. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes even compel us to create a more salubrious environment and pursue better lifestyles.

Principles of Evolutionary Medicine

Principles of Evolutionary Medicine PDF Author: Peter D. Gluckman
Publisher: Oxford University Press
ISBN: 0199663920
Category : Medical
Languages : en
Pages : 401

Book Description
A new updated edition of the first integrated and comprehensive textbook to explain the principles of evolutionary biology from a medical perspective and to focus on how medicine and public health might utilise evolutionary biology.

A History of the Brain

A History of the Brain PDF Author: Andrew P. Wickens
Publisher: Psychology Press
ISBN: 1317744837
Category : Psychology
Languages : en
Pages : 405

Book Description
A History of the Brain tells the full story of neuroscience, from antiquity to the present day. It describes how we have come to understand the biological nature of the brain, beginning in prehistoric times, and progressing to the twentieth century with the development of Modern Neuroscience. This is the first time a history of the brain has been written in a narrative way, emphasizing how our understanding of the brain and nervous system has developed over time, with the development of the disciplines of anatomy, pharmacology, physiology, psychology and neurosurgery. The book covers: beliefs about the brain in ancient Egypt, Greece and Rome the Medieval period, Renaissance and Enlightenment the nineteenth century the most important advances in the twentieth century and future directions in neuroscience. The discoveries leading to the development of modern neuroscience gave rise to one of the most exciting and fascinating stories in the whole of science. Written for readers with no prior knowledge of the brain or history, the book will delight students, and will also be of great interest to researchers and lecturers with an interest in understanding how we have arrived at our present knowledge of the brain.

Evolution's Bite

Evolution's Bite PDF Author: Peter S. Ungar
Publisher: Princeton University Press
ISBN: 0691182833
Category : Science
Languages : en
Pages : 248

Book Description
Whether we realize it or not, we carry in our mouths the legacy of our evolution. Our teeth are like living fossils that can be studied and compared to those of our ancestors to teach us how we became human. In Evolution’s Bite, noted paleoanthropologist Peter Ungar brings together for the first time cutting-edge advances in understanding human evolution with new approaches to uncovering dietary clues from fossil teeth. The result is a remarkable investigation into the ways that teeth—their shape, chemistry, and wear—reveal how we came to be. Traveling the four corners of the globe and combining scientific breakthroughs with vivid narrative, Evolution’s Bite presents a unique dental perspective on our astonishing human development.

The Cambridge Handbook of Evolutionary Perspectives on Human Behavior

The Cambridge Handbook of Evolutionary Perspectives on Human Behavior PDF Author: Lance Workman
Publisher: Cambridge University Press
ISBN: 1108900968
Category : Psychology
Languages : en
Pages : 1570

Book Description
The transformative wave of Darwinian insight continues to expand throughout the human sciences. While still centered on evolution-focused fields such as evolutionary psychology, ethology, and human behavioral ecology, this insight has also influenced cognitive science, neuroscience, feminist discourse, sociocultural anthropology, media studies, and clinical psychology. This handbook's goal is to amplify the wave by bringing together world-leading experts to provide a comprehensive and up-to-date overview of evolution-oriented and influenced fields. While evolutionary psychology remains at the core of the collection, it also covers the history, current standing, debates, and future directions of the panoply of fields entering the Darwinian fold. As such, The Cambridge Handbook of Evolutionary Perspectives on Human Behavior is a valuable reference not just for evolutionary psychologists but also for scholars and students from many fields who wish to see how the evolutionary perspective is relevant to their own work.

Origins of Neuroscience

Origins of Neuroscience PDF Author: Stanley Finger
Publisher:
ISBN: 9780195146943
Category : Medical
Languages : en
Pages : 484

Book Description
With over 350 illustrations, this impressive volume traces the rich history of ideas about the functioning of the brain from its roots in the ancient cultures of Egypt, Greece, and Rome through the centuries into relatively modern times. In contrast to biographically oriented accounts, this book is unique in its emphasis on the functions of the brain and how they came to be associated with specific brain regions and systems. Among the topics explored are vision, hearing, pain, motor control, sleep, memory, speech, and various other facets of intellect. The emphasis throughout is on presenting material in a very readable way, while describing with scholarly acumen the historical evolution of the field in all its amazing wealth and detail. From the opening introductory chapters to the concluding look at treatments and therapies, this monumental work will captivate readers from cover to cover. It will be valued as both an historical reference and as an exciting tale of scientificdiscovery. It is bound to attract a wide readership among students and professionals in the neural sciences as well as general readers interested in the history of science and medicine.

What Is Health?

What Is Health? PDF Author: Peter Sterling
Publisher: MIT Press
ISBN: 0262043300
Category : Science
Languages : en
Pages : 259

Book Description
An argument that health is optimal responsiveness and is often best treated at the system level. Medical education centers on the venerable “no-fault” concept of homeostasis, whereby local mechanisms impose constancy by correcting errors, and the brain serves mainly for emergencies. Yet, it turns out that most parameters are not constant; moreover, despite the importance of local mechanisms, the brain is definitely in charge. In this book, the eminent neuroscientist Peter Sterling describes a broader concept: allostasis (coined by Sterling and Joseph Eyer in the 1980s), whereby the brain anticipates needs and efficiently mobilizes supplies to prevent errors. Allostasis evolved early, Sterling explains, to optimize energy efficiency, relying heavily on brain circuits that deliver a brief reward for each positive surprise. Modern life so reduces the opportunities for surprise that we are driven to seek it in consumption: bigger burgers, more opioids, and innumerable activities that involve higher carbon emissions. The consequences include addiction, obesity, type 2 diabetes, and climate change. Sterling concludes that solutions must go beyond the merely technical to restore possibilities for daily small rewards and revivify the capacities for egalitarianism that were hard-wired into our nature. Sterling explains that allostasis offers what is not found in any medical textbook: principled definitions of health and disease: health as the capacity for adaptive variation and disease as shrinkage of that capacity. Sterling argues that since health is optimal responsiveness, many significant conditions are best treated at the system level.