The Effect of Acetoacetic Acid Injected Subcutaneously Upon the Action of Insulin PDF Download

Author: Leila Ellen Woolverton
Publisher:
ISBN:
Category :
Languages : en
Pages : 84

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Author: Dorothy Vermila Whipple
Publisher:
ISBN:
Category :
Languages : en
Pages : 92

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Author: Mark A. Sperling
Publisher:
ISBN: 9781416027539
Category : Children
Languages : en
Pages : 0

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Author: Stephen C. Duck
Publisher: Nova Science Publishers
ISBN: 9781634832205
Category : Diabetes in adolescence
Languages : en
Pages : 0

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The future of persons with Type 1 Diabetes Mellitus is continuing to "look brighter" with the advent of biomedical technology. Nevertheless, the acute consequences of this disease remains a significant threat. Diabetic ketoacidosis [DKA] remains the most serious challenge for primary care physicians and subspecialists caring for children and young persons with Diabetes Mellitus. Its prevention is possible only among those already diagnosed. Awareness of the etiology and clinical presenting signs among children of all ages is requisite for primary care and emergency department staff [Chapter 1]. While more likely to occur among those with Type 1 diabetes, a significant proportion of children with Type 2 diabetes are also at risk [Chapter 3]. Once diagnosed, the physician team must understand not only what biochemical imbalances must be corrected, but also what life-threatening complications must be avoided [Chapter 1]. The path through that "maze" is not yet fully interpreted; many choices remain as options, but each must be carefully evaluated. Diagnosis among the very young is a challenge because of they lack self-awareness and clarity of signs and symptoms [Chapter 2]. Education of the primary care staff is critical and able to alter the incidence of DKA at the time of diagnosis. Institutions that treat children and adolescents with DKA need an informed Emergency Department as well as Pediatric Intensive Care Facilities. Access to appropriate consultations, such as pediatric endocrinology, cardiology, neurology and neurosurgery are crucial. The initiation of care is critical, and occurs invariably in the Emergency Department [Chapter 4]. Meticulous documentation of fluid composition and volume, insulin administration, vital signs and neurological state of well-being is essential. These will facilitate the transition to the appropriate in-patient service, whose task is to understand the biological impact of fluid rehydration and fluid flux, as well as hypocapnea, hyperglycemia and cranial perfusion [Chapter 5]. The current standards of care all but prevent most of the varied biochemical complications of "appropriate" care for persons with DKA. However, awareness of these possibilities is crucial [Chapter 6]. Yet, one complication remains unexplained and too often unpredicted, and it is devastating to the pediatric patient: cerebral edema. This complication, its prevention and treatment are discussed [Chapter 6]. Type 2 diabetes mellitus is continuing to increase in incidence and prevalence among all ages. Once thought to be "non-ketosis prone" diabetes, now persons undiagnosed or previously diagnosed do obtain DKA. They, however, have other unique medical requirements that must be applied to their treatment [Chapter 3]. Hyperglycemic hyperosmolar state is a complication no longer limited to adults with diabetes or children with Type 2 diabetes mellitus. While the incidence is fortunately lower than that of DKA, its outcome is potentially direr. Appreciation of the unique treatment requirements and guidelines are discussed [Chapter 7]. This monograph provides a comprehensive compendium to those caring for children of all ages with diabetic ketoacidosis, its related disorders and associated conditions.

Author:
Publisher:
ISBN:
Category : Physiology
Languages : en
Pages : 736

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Author: T.A. Sonia
Publisher: Elsevier
ISBN: 1908818689
Category : Medical
Languages : en
Pages : 361

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Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus. Subsequent chapters cover the various routes for administering insulin; the challenges and strategies of oral delivery; experimental techniques in the development of an oral insulin carrier; lipids; inorganic nanoparticles and polymers in oral insulin delivery; and a summary and presentation of future perspectives on oral delivery of insulin. - Presents an overview of Diabetes Mellitus - Includes a discussion of various strategies and techniques adopted for oral delivery of insulin - Presents an update of research in the field

Author: Hans G. Vogel
Publisher: Springer Science & Business Media
ISBN: 366203333X
Category : Medical
Languages : en
Pages : 790

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This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs, including tests for cardiovascular, analgesic, psychotropic, metabolic, endocrine, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results and their pharmacological and clinical relevance, and pertinent references. Identification of specific tests is facilitated by the enclosed CD-ROM which allows for a quick and full text research. An appendix with guidelines and legal regulations for animal experiments in various countries will help to plan these experiments properly in accordance with the welfare of laboratory animals.

Author: Yves Chartier
Publisher: World Health Organization
ISBN: 9241548568
Category : Medical
Languages : en
Pages : 327

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This is the second edition of the WHO handbook on the safe, sustainable and affordable management of health-care waste--commonly known as "the Blue Book". The original Blue Book was a comprehensive publication used widely in health-care centers and government agencies to assist in the adoption of national guidance. It also provided support to committed medical directors and managers to make improvements and presented practical information on waste-management techniques for medical staff and waste workers. It has been more than ten years since the first edition of the Blue Book. During the intervening period, the requirements on generators of health-care wastes have evolved and new methods have become available. Consequently, WHO recognized that it was an appropriate time to update the original text. The purpose of the second edition is to expand and update the practical information in the original Blue Book. The new Blue Book is designed to continue to be a source of impartial health-care information and guidance on safe waste-management practices. The editors' intention has been to keep the best of the original publication and supplement it with the latest relevant information. The audience for the Blue Book has expanded. Initially, the publication was intended for those directly involved in the creation and handling of health-care wastes: medical staff, health-care facility directors, ancillary health workers, infection-control officers and waste workers. This is no longer the situation. A wider range of people and organizations now have an active interest in the safe management of health-care wastes: regulators, policy-makers, development organizations, voluntary groups, environmental bodies, environmental health practitioners, advisers, researchers and students. They should also find the new Blue Book of benefit to their activities. Chapters 2 and 3 explain the various types of waste produced from health-care facilities, their typical characteristics and the hazards these wastes pose to patients, staff and the general environment. Chapters 4 and 5 introduce the guiding regulatory principles for developing local or national approaches to tackling health-care waste management and transposing these into practical plans for regions and individual health-care facilities. Specific methods and technologies are described for waste minimization, segregation and treatment of health-care wastes in Chapters 6, 7 and 8. These chapters introduce the basic features of each technology and the operational and environmental characteristics required to be achieved, followed by information on the potential advantages and disadvantages of each system. To reflect concerns about the difficulties of handling health-care wastewaters, Chapter 9 is an expanded chapter with new guidance on the various sources of wastewater and wastewater treatment options for places not connected to central sewerage systems. Further chapters address issues on economics (Chapter 10), occupational safety (Chapter 11), hygiene and infection control (Chapter 12), and staff training and public awareness (Chapter 13). A wider range of information has been incorporated into this edition of the Blue Book, with the addition of two new chapters on health-care waste management in emergencies (Chapter 14) and an overview of the emerging issues of pandemics, drug-resistant pathogens, climate change and technology advances in medical techniques that will have to be accommodated by health-care waste systems in the future (Chapter 15).

Author:
Publisher:
ISBN:
Category : Electronic journals
Languages : en
Pages : 1144

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Includes proceedings of the association, papers read at the annual sessions, and lists of current medical literature.

Author:
Publisher:
ISBN:
Category : Biochemistry
Languages : en
Pages : 910

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Vols. 3- include the society's Proceedings, 1907-