Author: Antoine Depaulis
Publisher: Springer Science & Business Media
ISBN: 1461533023
Category : Medical
Languages : en
Pages : 469
Book Description
This book constitutes the proceedings of a NATO Advanced Research Workshop held at Chateau de Bonas (France) from 10-15 July 1990 on the Midbrain Periaqueductal Gray Matter (PAG). The aim of this meeting was to review and integrate our knowledge about the functional, anatomical and neuro chemical organization of the PAG. The PAG has been the subject of many investi gations during the last decade usually on different topics (e.g., pain modulation, defensive and sexual behavior) and generally there has been little interchange between the different research areas. The main purpose of this meeting was to bring together, for the first time, scientists who have worked on the PAG from different perspectives. This book does not pretend to present an exhaustive review of the data collected during the last 20 years of research on the PAG. The contributors to this book have been selected because their data provide key elements in the search to understand both the organization of the PAG and the role of this structure in the integration of behavior. We believe that this book will provide clues that will assist in unraveling the organization of the PAG in the coming years.
The Midbrain Periaqueductal Gray Matter
Author: Antoine Depaulis
Publisher: Springer Science & Business Media
ISBN: 1461533023
Category : Medical
Languages : en
Pages : 469
Book Description
This book constitutes the proceedings of a NATO Advanced Research Workshop held at Chateau de Bonas (France) from 10-15 July 1990 on the Midbrain Periaqueductal Gray Matter (PAG). The aim of this meeting was to review and integrate our knowledge about the functional, anatomical and neuro chemical organization of the PAG. The PAG has been the subject of many investi gations during the last decade usually on different topics (e.g., pain modulation, defensive and sexual behavior) and generally there has been little interchange between the different research areas. The main purpose of this meeting was to bring together, for the first time, scientists who have worked on the PAG from different perspectives. This book does not pretend to present an exhaustive review of the data collected during the last 20 years of research on the PAG. The contributors to this book have been selected because their data provide key elements in the search to understand both the organization of the PAG and the role of this structure in the integration of behavior. We believe that this book will provide clues that will assist in unraveling the organization of the PAG in the coming years.
Publisher: Springer Science & Business Media
ISBN: 1461533023
Category : Medical
Languages : en
Pages : 469
Book Description
This book constitutes the proceedings of a NATO Advanced Research Workshop held at Chateau de Bonas (France) from 10-15 July 1990 on the Midbrain Periaqueductal Gray Matter (PAG). The aim of this meeting was to review and integrate our knowledge about the functional, anatomical and neuro chemical organization of the PAG. The PAG has been the subject of many investi gations during the last decade usually on different topics (e.g., pain modulation, defensive and sexual behavior) and generally there has been little interchange between the different research areas. The main purpose of this meeting was to bring together, for the first time, scientists who have worked on the PAG from different perspectives. This book does not pretend to present an exhaustive review of the data collected during the last 20 years of research on the PAG. The contributors to this book have been selected because their data provide key elements in the search to understand both the organization of the PAG and the role of this structure in the integration of behavior. We believe that this book will provide clues that will assist in unraveling the organization of the PAG in the coming years.
Motor Function of the Pharynx, Esophagus, and Its Sphincters
Author: Ravinder Mittal
Publisher: Morgan & Claypool Publishers
ISBN: 1615043330
Category : Medical
Languages : en
Pages : 87
Book Description
Deglutition or a swallow begins as a voluntary act in the oral cavity but proceeds autonomously in the pharynx and esophagus. Bilateral sequenced activation and inhibition of more than 25 pairs of muscles of mouth, pharynx, larynx, and esophagus is required during a swallow. A single swallow elicits peristalsis in the pharynx and esophagus along with relaxation of upper and lower esophageal sphincters. Multiple swallows, at closely spaced time intervals, demonstrate deglutitive inhibition; sphincters remain relaxed during the entire period, but only the last swallow elicits peristalsis. Laryngeal inlet closure or airway protection is very important during swallow. Upper part of the esophagus that includes upper esophageal sphincter is composed of skeletal muscles, middle esophagus is composed of a mixture of skeletal and smooth muscles, and lower esophagus, including lower esophageal sphincter, is composed of smooth muscles. Peristalsis progresses in seamless fashion, despite separate control mechanism, from the skeletal to smooth muscle esophagus. The esophagus's circular and longitudinal muscle layers contract synchronously during peristalsis. Sphincters maintain continuous tone; neuromuscular mechanisms for tonic closure in the upper and lower esophageal sphincters are different. Lower esophageal sphincter transient relaxation, belching mechanism, regurgitation, vomiting, and reflux are mediated via the brain stem. Table of Contents: Introduction / Central Program Generator and Brain Stem / Pharynx-Anatomy, Neural Innervation, and Motor Pattern / Upper Esophageal Sphincter / Neuromuscular Anatomy of Esophagus and Lower Esophageal Sphincter / Extrinsic Innervation: Parasympathetic and Sympathetic / Interstitial Cells of Cajal / Recording Techniques / Motor Patterns of the Esophagus-Aboral and Oral Transport / Deglutitive Inhibition and Muscle Refractoriness / Peristalsis in the Circular and Longitudinal Muscles of the Esophagus / Neural and Myogenic Mechanism of Peristalsis / Central Mechanism of Peristalsis-Cortical and Brain Stem Control / Peripheral Mechanisms of Peristalsis / Central Versus Peripheral Mechanism of Deglutitive Inhibition / Neural Control of Longitudinal Muscle Contraction / Modulation of Primary and Secondary Peristalsis / Neural Control of Lower Esophageal Sphincter and Crural Diaphragm / Lower Esophageal Sphincter / Swallow-Induced LES Relaxation / Crural Diaphragm Contribution to EGJ and Neural Control / Transient LES Relaxation and Pharmacological Inhibition / Compliance of the EGJ / References
Publisher: Morgan & Claypool Publishers
ISBN: 1615043330
Category : Medical
Languages : en
Pages : 87
Book Description
Deglutition or a swallow begins as a voluntary act in the oral cavity but proceeds autonomously in the pharynx and esophagus. Bilateral sequenced activation and inhibition of more than 25 pairs of muscles of mouth, pharynx, larynx, and esophagus is required during a swallow. A single swallow elicits peristalsis in the pharynx and esophagus along with relaxation of upper and lower esophageal sphincters. Multiple swallows, at closely spaced time intervals, demonstrate deglutitive inhibition; sphincters remain relaxed during the entire period, but only the last swallow elicits peristalsis. Laryngeal inlet closure or airway protection is very important during swallow. Upper part of the esophagus that includes upper esophageal sphincter is composed of skeletal muscles, middle esophagus is composed of a mixture of skeletal and smooth muscles, and lower esophagus, including lower esophageal sphincter, is composed of smooth muscles. Peristalsis progresses in seamless fashion, despite separate control mechanism, from the skeletal to smooth muscle esophagus. The esophagus's circular and longitudinal muscle layers contract synchronously during peristalsis. Sphincters maintain continuous tone; neuromuscular mechanisms for tonic closure in the upper and lower esophageal sphincters are different. Lower esophageal sphincter transient relaxation, belching mechanism, regurgitation, vomiting, and reflux are mediated via the brain stem. Table of Contents: Introduction / Central Program Generator and Brain Stem / Pharynx-Anatomy, Neural Innervation, and Motor Pattern / Upper Esophageal Sphincter / Neuromuscular Anatomy of Esophagus and Lower Esophageal Sphincter / Extrinsic Innervation: Parasympathetic and Sympathetic / Interstitial Cells of Cajal / Recording Techniques / Motor Patterns of the Esophagus-Aboral and Oral Transport / Deglutitive Inhibition and Muscle Refractoriness / Peristalsis in the Circular and Longitudinal Muscles of the Esophagus / Neural and Myogenic Mechanism of Peristalsis / Central Mechanism of Peristalsis-Cortical and Brain Stem Control / Peripheral Mechanisms of Peristalsis / Central Versus Peripheral Mechanism of Deglutitive Inhibition / Neural Control of Longitudinal Muscle Contraction / Modulation of Primary and Secondary Peristalsis / Neural Control of Lower Esophageal Sphincter and Crural Diaphragm / Lower Esophageal Sphincter / Swallow-Induced LES Relaxation / Crural Diaphragm Contribution to EGJ and Neural Control / Transient LES Relaxation and Pharmacological Inhibition / Compliance of the EGJ / References
Functional Organization of Brain Stem Respiratory Complex in the Cat
Author: Pei Chin Tang
Publisher:
ISBN:
Category : Brain stem
Languages : en
Pages : 40
Book Description
A study was made on the roles of the Hering-Breuer reflex, the pneumotaxic center, the apneustic center, and the medullary respiratory center in the regulation of rate and depth of respiration in response to changes in blood concentration of CO2 and 02. Integrated phrenic nerve discharge, abdominal respiratory movement, and intra-abdominal and intratracheal pressures were recorded in decerebrate cats as they breathed air, 5% CO2, 7% CO2, 10% 02 and 100% 02. By using decerebrate cats as control, results from vagotomy, pneumotaxic center ablation, and brain stem transection, alone or in combination, indicate: (1) Hering-Breuer reflex controls respiratory rate and in the absence of pneumotaxic center, maintains a constant depth; (2) pneumotaxic center controls respiratory depth and in the absence of Hering-Breuer reflex, maintains a constant rate; (3) apneustic center provides maximum respiratory depth and prolonged inspiratory duration so that rate can be regulated by Hering-Breuer reflex and depth by pneumotaxic center; (4) medullary respiratory center serves as a final pathway and integration center of the impulses from the higher centers. (Author).
Publisher:
ISBN:
Category : Brain stem
Languages : en
Pages : 40
Book Description
A study was made on the roles of the Hering-Breuer reflex, the pneumotaxic center, the apneustic center, and the medullary respiratory center in the regulation of rate and depth of respiration in response to changes in blood concentration of CO2 and 02. Integrated phrenic nerve discharge, abdominal respiratory movement, and intra-abdominal and intratracheal pressures were recorded in decerebrate cats as they breathed air, 5% CO2, 7% CO2, 10% 02 and 100% 02. By using decerebrate cats as control, results from vagotomy, pneumotaxic center ablation, and brain stem transection, alone or in combination, indicate: (1) Hering-Breuer reflex controls respiratory rate and in the absence of pneumotaxic center, maintains a constant depth; (2) pneumotaxic center controls respiratory depth and in the absence of Hering-Breuer reflex, maintains a constant rate; (3) apneustic center provides maximum respiratory depth and prolonged inspiratory duration so that rate can be regulated by Hering-Breuer reflex and depth by pneumotaxic center; (4) medullary respiratory center serves as a final pathway and integration center of the impulses from the higher centers. (Author).
Acetylthiocholinesterase Distribution in the Brain Stem of the Cat
Author: E. Ramon-Moliner
Publisher: Springer Science & Business Media
ISBN: 3642500552
Category : Medical
Languages : en
Pages : 53
Book Description
The earliest studies on the regional distribution of acetylcholinesterase (AChE) within the central nervous system were based on the determination of the amount of CO liberated by homogenates of selected areas in the presence of an ester of 2 choline and a bicarbonate buffer. Using this biochemical approach, Burgen and Chipman (1951) were able to establish that acetylcholinesterase is not evenly distributed within the central nervous system. They found that the cerebellum, the lateral geniculate body, and the striatum contained a high concentration of AChE. The high concentration of AChE in the striatum could be correlated with a higher rate of acetylcholine synthesis. However, this was not the case for the cerebellum, where acetylcholine synthesis was very low. Other in vitro studies have been aimed at establishing the regional distribution of the other two components of the cholinergic system, cholinacetylase (ChA) and acetylcholine (ACh). An equally asymetrical distribution for these substances has been established in vitro (MacIntosh, 1941 ; Feldberg and Mann, 1946; Feldberg and V ogt, 1948; MacIntosh and Oborin, 1953; Quastel, 1962; Mitchell, 1963; Krnjevic and Phillis, 1963; Aprison et al., 1964; McLennan, 1964; Cohen, 1956). The in vitro determination of acetylcholinesterase (Koelle, 1950; Burgen and Chipman, 1951; Giacobini, 1959; Bennett et al., 1966; Fahn and Cote, 1968; Miller et al., 1969) presents the advan tage of permitting the use of a substrate like ACh which is a normally occurring ester of choline so that the establishment of enzyme specificity is less questionable.
Publisher: Springer Science & Business Media
ISBN: 3642500552
Category : Medical
Languages : en
Pages : 53
Book Description
The earliest studies on the regional distribution of acetylcholinesterase (AChE) within the central nervous system were based on the determination of the amount of CO liberated by homogenates of selected areas in the presence of an ester of 2 choline and a bicarbonate buffer. Using this biochemical approach, Burgen and Chipman (1951) were able to establish that acetylcholinesterase is not evenly distributed within the central nervous system. They found that the cerebellum, the lateral geniculate body, and the striatum contained a high concentration of AChE. The high concentration of AChE in the striatum could be correlated with a higher rate of acetylcholine synthesis. However, this was not the case for the cerebellum, where acetylcholine synthesis was very low. Other in vitro studies have been aimed at establishing the regional distribution of the other two components of the cholinergic system, cholinacetylase (ChA) and acetylcholine (ACh). An equally asymetrical distribution for these substances has been established in vitro (MacIntosh, 1941 ; Feldberg and Mann, 1946; Feldberg and V ogt, 1948; MacIntosh and Oborin, 1953; Quastel, 1962; Mitchell, 1963; Krnjevic and Phillis, 1963; Aprison et al., 1964; McLennan, 1964; Cohen, 1956). The in vitro determination of acetylcholinesterase (Koelle, 1950; Burgen and Chipman, 1951; Giacobini, 1959; Bennett et al., 1966; Fahn and Cote, 1968; Miller et al., 1969) presents the advan tage of permitting the use of a substrate like ACh which is a normally occurring ester of choline so that the establishment of enzyme specificity is less questionable.
A Stereotactic Atlas of the Brain Stem of the Cat
Author: W. J. C. Verhaart
Publisher:
ISBN:
Category : Brain
Languages : en
Pages : 100
Book Description
Publisher:
ISBN:
Category : Brain
Languages : en
Pages : 100
Book Description
Neurobiology of Vertebrate Locomotion
Author: Sten Grillner
Publisher: Springer
ISBN: 1349091480
Category : Science
Languages : en
Pages : 719
Book Description
Publisher: Springer
ISBN: 1349091480
Category : Science
Languages : en
Pages : 719
Book Description
The Inferior Colliculus
Author: Jeffery A. Winer
Publisher: Springer Science & Business Media
ISBN: 0387270833
Category : Science
Languages : en
Pages : 720
Book Description
Connecting the auditory brain stem to sensory, motor, and limbic systems, the inferior colliculus is a critical midbrain station for auditory processing. Winer and Schreiner's The Inferior Colliculus, a critical, comprehensive reference, presents the current knowledge of the inferior colliculus from a variety of perspectives, including anatomical, physiological, developmental, neurochemical, biophysical, neuroethological and clinical vantage points. Written by leading researchers in the field, the book is an ideal introduction to the inferior colliculus and central auditory processing for clinicians, otolaryngologists, graduate and postgraduate research workers in the auditory and other sensory-motor systems.
Publisher: Springer Science & Business Media
ISBN: 0387270833
Category : Science
Languages : en
Pages : 720
Book Description
Connecting the auditory brain stem to sensory, motor, and limbic systems, the inferior colliculus is a critical midbrain station for auditory processing. Winer and Schreiner's The Inferior Colliculus, a critical, comprehensive reference, presents the current knowledge of the inferior colliculus from a variety of perspectives, including anatomical, physiological, developmental, neurochemical, biophysical, neuroethological and clinical vantage points. Written by leading researchers in the field, the book is an ideal introduction to the inferior colliculus and central auditory processing for clinicians, otolaryngologists, graduate and postgraduate research workers in the auditory and other sensory-motor systems.
Organization of the Spinal Cord
Author:
Publisher: Elsevier
ISBN: 0080861350
Category : Medical
Languages : en
Pages : 297
Book Description
This volume includes contributions from almost all of the leading neuroanatomists who have in recent years devoted their attention to the spinal cord.
Publisher: Elsevier
ISBN: 0080861350
Category : Medical
Languages : en
Pages : 297
Book Description
This volume includes contributions from almost all of the leading neuroanatomists who have in recent years devoted their attention to the spinal cord.
Brainstem Control of Wakefulness and Sleep
Author: Mircea M. Steriade
Publisher: Springer Science & Business Media
ISBN: 1475746695
Category : Medical
Languages : en
Pages : 504
Book Description
This book is part of an ongoing history of efforts to understand the nature of waking and sleeping states from a biological point of view. We believe the recent technological revolutions in anatomy and physiology make the present moment especially propitious for this effort. In planning this book we had the choices of producing an edited volume with invited chapter authors or of writing the book ourselves. Edited volumes offer the opportunity for expression of expertise in each chapter but, we felt, would not allow the development of our ideas on the potential and actual unity of the field and would not allow the expression of coherence that can be obtained only with one or two voices, but which may be quite difficult with a chorus assembled and performing together for the first time. (Unlike musical works, there is very little precedent for rehearsals and repeated performances for authors of edited volumes or even for the existence of conductors able to induce a single rhythm and vision of the composition. ) We thus decided on a monograph. The primary goal was to communicate the current realities and the future possibilities of unifying basic studies on anatomy and cellular physiology with investigations of the behavioral and physi ological events of waking and sleep. In keeping with this goal we cross-reference the basic cellular physiology in the latter chapters, and, in the last chapter, we take up possible links to relevant clinical phenomenology.
Publisher: Springer Science & Business Media
ISBN: 1475746695
Category : Medical
Languages : en
Pages : 504
Book Description
This book is part of an ongoing history of efforts to understand the nature of waking and sleeping states from a biological point of view. We believe the recent technological revolutions in anatomy and physiology make the present moment especially propitious for this effort. In planning this book we had the choices of producing an edited volume with invited chapter authors or of writing the book ourselves. Edited volumes offer the opportunity for expression of expertise in each chapter but, we felt, would not allow the development of our ideas on the potential and actual unity of the field and would not allow the expression of coherence that can be obtained only with one or two voices, but which may be quite difficult with a chorus assembled and performing together for the first time. (Unlike musical works, there is very little precedent for rehearsals and repeated performances for authors of edited volumes or even for the existence of conductors able to induce a single rhythm and vision of the composition. ) We thus decided on a monograph. The primary goal was to communicate the current realities and the future possibilities of unifying basic studies on anatomy and cellular physiology with investigations of the behavioral and physi ological events of waking and sleep. In keeping with this goal we cross-reference the basic cellular physiology in the latter chapters, and, in the last chapter, we take up possible links to relevant clinical phenomenology.
Atlas of the Human Brainstem
Author: George Paxinos
Publisher: Elsevier
ISBN: 0080925219
Category : Science
Languages : en
Pages : 150
Book Description
Work on the human brainstem has been impeded by the unavailability of a comprehensive diagrammatic and photographic atlas. In the authors' preliminary work on the morphology of the human brainstem (The Human Nervous System, 1990), Paxinos et al demonstrated that it is possible to use chemoarchitecture to establish a number of human homologs in structures known to exist in the rat, the most extensively studied species. Now, with the first detailed atlas on the human brainstem in more than forty years, the authors present an accurate, comprehensive, and convenient reference for students, researchers, and pathologists. Key Features * The first detailed atlas on the human brainstem in more than forty years * Delineated as accurately as The Rat Brain in Stereotaxic Coordinates, Second Edition (Paxinos/Watson, 1986), the most cited book in neuroscience * Based on a single brain from a 59-year-old male with no medical history of neurological or psychiatric illness * Represents all areas of the medulla, pons, and midbrain in the plane transverse to the longitudinal axis of the brainstem * Consists of 64 plates and 64 accompanying diagrams with an interplate distance of half a millimeter * The photographs are of Nissl and acetylcholinesterase (AChE) stained sections at alternate levels * Establishes systematically the human homologs to nuclei identified in the brainstem of the rat Reviewed by leading neuroanatomists * An accurate and convenient guide for students, researchers, and pathologists
Publisher: Elsevier
ISBN: 0080925219
Category : Science
Languages : en
Pages : 150
Book Description
Work on the human brainstem has been impeded by the unavailability of a comprehensive diagrammatic and photographic atlas. In the authors' preliminary work on the morphology of the human brainstem (The Human Nervous System, 1990), Paxinos et al demonstrated that it is possible to use chemoarchitecture to establish a number of human homologs in structures known to exist in the rat, the most extensively studied species. Now, with the first detailed atlas on the human brainstem in more than forty years, the authors present an accurate, comprehensive, and convenient reference for students, researchers, and pathologists. Key Features * The first detailed atlas on the human brainstem in more than forty years * Delineated as accurately as The Rat Brain in Stereotaxic Coordinates, Second Edition (Paxinos/Watson, 1986), the most cited book in neuroscience * Based on a single brain from a 59-year-old male with no medical history of neurological or psychiatric illness * Represents all areas of the medulla, pons, and midbrain in the plane transverse to the longitudinal axis of the brainstem * Consists of 64 plates and 64 accompanying diagrams with an interplate distance of half a millimeter * The photographs are of Nissl and acetylcholinesterase (AChE) stained sections at alternate levels * Establishes systematically the human homologs to nuclei identified in the brainstem of the rat Reviewed by leading neuroanatomists * An accurate and convenient guide for students, researchers, and pathologists