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The Brain in Bits and Pieces

The Brain in Bits and Pieces PDF Author: Gerhard Zbinden
Publisher:
ISBN: 9783907037034
Category : Brain
Languages : en
Pages : 184

Book Description


The Brain in Bits and Pieces

The Brain in Bits and Pieces PDF Author: Gerhard Zbinden
Publisher:
ISBN: 9783907037034
Category : Brain
Languages : en
Pages : 184

Book Description


Neurotoxicology

Neurotoxicology PDF Author: Louis W. Chang
Publisher: Elsevier
ISBN: 0080537472
Category : Science
Languages : en
Pages : 875

Book Description
Neurotoxicology: Approaches and Methods provides a unique and comprehensive presentation of the current concepts and state-of-the-art methods for the assessment of neurotoxicity. The book analyzes various techniques available and discusses their strengths and weaknesses. This volume will serve as an excellent desk companion and laboratory guide for all investigators, researchers, clinicians, and students interested in neurotoxicology. The internationally knowngroup of editors divide the book into seven sections: Neuromorphological and Neuropathological Approaches; Neurophysiological Approaches; Neurobehavioral Toxicology; Neurochemical and Biomolecular Approaches; In-Vitro Models; Clinical Neurotoxicology; and Risk Assessment of Neurotoxicity. Each section yields the most up-to-date information by experts in their fields. Meticulously organized and edited, Neurotoxicology: Approaches and Methods is the most authoritative and well-planned neurotoxicology book on the market. - Discusses neurobehavioral testing methods for assessment of neural dysfunctions - Explains state-of-the-art diagnostic methods, such as clinico-neuropsychological and neurophysiological methods, for patients confronted by neurotoxic problems - Discusses In Vitro methods, including aggregating brain cell methods, organotypic cultures, and the use of human neuronal cell lines for the assessment of neurotoxicity - Presents step-by-step procedures for many methods - Provides state-of-the-art neuromorphological and biomolecular methods and approaches for neurotoxicity investigation

Current Catalog

Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 824

Book Description
First multi-year cumulation covers six years: 1965-70.

Cell Culture Methods for In Vitro Toxicology

Cell Culture Methods for In Vitro Toxicology PDF Author: G. Stacey
Publisher: Springer Science & Business Media
ISBN: 9401709963
Category : Medical
Languages : en
Pages : 166

Book Description
Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies. It deals with major cell types studied in the field of toxicology and will be useful for anyone wishing to start work with animal cell cultures or to refresh their knowledge relating to in vitro cell models. Fundamental chapters deal with the general biology of cytotoxicity and cell immortalisation these are key issues for in vitro systems addressing the `3Rs' principle. Up-to-date overviews deal with the use of cells from liver, brain and intestine. In addition, biochemical analysis of cell responses, biotransformation pathways in cells and recombinant approaches to the early detection of cell stress are also covered in detail. Prominent features of in vitro technologies also include regulation, biosafety and standardisation. Dedicated chapters deal with these issues in a practical way in order to lead the reader to the right source of information. This book provides an up-to-date, informative and practical review of cell culture methods for in vitro toxicology. It will be of equal benefit to students and experienced toxicologists with little experience of in vitro cell culture.

Toxicology in Transition

Toxicology in Transition PDF Author: Gisela H. Degen
Publisher: Springer Science & Business Media
ISBN: 3642794513
Category : Medical
Languages : en
Pages : 559

Book Description
The volume contains the main papers presented at the 1994 EUROTOX Congress, Basel, Switzerland, August 21-24, 1994. Toxicology has become a less descriptive science because more importance has been placed on the mechanisms underlying toxic effects. This is reflected in symposia and workshops devoted to species differences in organ toxicity, receptor-mediated toxicity and stereochemical effects of xenobiotics. Recent progress in the fields of immunotoxicology, ecotoxicology, and neurotoxicology is highlighted and documented together with the present discussion on harmonized regulatory guidelines.

Protocols for Neural Cell Culture

Protocols for Neural Cell Culture PDF Author: Sergey Fedoroff
Publisher: Springer Science & Business Media
ISBN: 1475725868
Category : Medical
Languages : en
Pages : 284

Book Description
This volume is designed to be kept close at hand as a ready reference and a guide to laboratory procedures. It is based on tissue culture manuals used for a number of years at international courses on tissue culture at the University of Saskatchewan, made possible by the generous support of the Canadian Council of Animal Care and the Medical Research Council of Canada. Sergey Fedoroff Arleen Richardson The second edition of Protocols for Neural Cell Culture adheres to the prin ciples enunciated in the first edition, but the content has been extensively revised and expanded. Two new chapters have been added to reflect the increased interest in the development and differentiation of the nervous system and in the reconstruction of its circuitry in tissue culture. One chapter deals with slice cul tures in which the organization of the nervous system is preserved. When slice cultures are combined with explant cultures, afferent and efferent projections can be reconstructed. The other chapter deals with aggregating neural cell cul tures, in which "minibrains" can form. Theses are small, uniformly sized spheres of nervous tissue, usually having nerve cells in the center and astrocytes, oligo dendrocytes, and microglia in the periphery. Such cultures can be used to study neutral cell interactions in an organized milieu and for qualitative as well as quantitative studies at biochemical and molecular levels.

In Vitro Methods in Pharmaceutical Research

In Vitro Methods in Pharmaceutical Research PDF Author: Jose V. Castell
Publisher: Elsevier
ISBN: 0080534600
Category : Medical
Languages : en
Pages : 483

Book Description
In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a comparison of different techniques available. It is a welcome addition to the literature at a time when interest is growing in cellular in vitro models for toxicology and pharmacology studies. - Meets the continuing demand for information in this field - Compares In Vitro techniques with other methods - Describes cell-culture methods used to investigate toxicity in cells derived from different organs - Includes contributions by leading experts in the field

National Library of Medicine Current Catalog

National Library of Medicine Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1536

Book Description


Neurotoxicology in Vitro

Neurotoxicology in Vitro PDF Author: V. Pentreath
Publisher: CRC Press
ISBN: 9780748403882
Category : Medical
Languages : en
Pages : 314

Book Description
Written by a distinguished panel of experts, students and researchers will find that this comprehensive and accessible volume provides a framework for the study of nerve cells ^in vitro^n for use in experimental neurotoxicology.

World Congress on Alternatives and Animal Use in the Life Sciences

World Congress on Alternatives and Animal Use in the Life Sciences PDF Author: Alan M. Goldberg
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 788

Book Description