Synthesis of Tricyclic Compounds PDF Download

Author: Herman R. Rodriguez
Publisher:
ISBN:
Category :
Languages : en
Pages : 184

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Author: Richard Lee Dunn
Publisher:
ISBN:
Category : Carbon compounds
Languages : en
Pages : 286

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Author: Michael C. Pirrung
Publisher: John Wiley & Sons
ISBN: 0470129638
Category : Science
Languages : en
Pages : 480

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Book Description
The past two decades have seen an explosion in research on the synthesis of sesquiterpenes, an important class of hydrocarbons commonly found in oils, resins, and balsams. Volume Eleven in The Total Synthesis of Natural Products series continues to review this dynamic area of chemistry. It features systematic, A-to-Z coverage of sesquiterpenes synthesized between 1979-1994-a sesquidecade. Focusing on bicyclic and tricyclic compounds in sesquiterpene synthesis, this authoritative work complements Volume Ten's coverage of acyclic and monocyclic sesquiterpenes. The authors comb through the hundreds of sesquiterpene syntheses already developed, consolidating the multitude of research papers, and providing extensive references as well as author and subject indexes. To keep the presentation manageable, they emphasize literature where natural products were prepared, leaving out natural ring systems or compounds whose structures were misassigned. This volume presents multiple syntheses of the same compound in chronological order, making the various steps of the synthetic strategy easily accessible. In addition, it addresses one of the most important developments in sesquiterpene research, namely the increase in compound targets prepared in an optically active form. And while syntheses of racemates are not specifically marked, legends for synthesis schemes producing optically active compounds include their absolute configurations, signs of optical rotation, or both. An important resource for organic chemists, pharmaceutical and medicinal chemists, natural prod-ucts chemists, and biochemists, The Total Synthesis of Natural Products offers valuable insight into the structure and makeup of sesquiterpenes while serving as a practical tool for locating any of the major classes of sesquiterpene compounds. An invaluable guide for the chemist interested in natural products. Providing a fascinating, comprehensive look at sesquiterpene synthesis, Volume Eleven of The Total Synthesis of Natural Products reviews sesquiterpenes synthesized in the period 1979-1994, continuing the coverage begun with Volume Ten in the series (see below). This authoritative work: Focuses on bicyclic and tricyclic sesquiterpenes. Explains the structure and makeup of this important class of hydrocarbons. Serves as a useful, practical tool for researchers interested in locating any of the major classes of sesquiterpene compounds. Provides multiple syntheses of the same compound chronologically, clearly showing the evolution of the synthetic strategy. Also available . . .THE TOTAL SYNTHESIS OF NATURAL PRODUCTS Volume Ten, Edited by David Goldsmith. A complement to this work, Volume Ten examines compounds with acyclic and monocyclic ring structures in sesquiterpene synthesis. 1997 (0-471-59679-5) 173 pp.

Author: Daniel Alfred Davis
Publisher:
ISBN:
Category : Clozapine
Languages : en
Pages : 84

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Author: James Underhill Piper
Publisher:
ISBN:
Category : Nitrogen
Languages : en
Pages : 66

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Author: Frank Stetz Morehouse
Publisher:
ISBN:
Category : Tricyclic compounds
Languages : en
Pages : 102

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Author: WIlliam Joseph Middleton
Publisher:
ISBN:
Category : Cyclization
Languages : en
Pages : 3

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Author: Neville Stanton Crossley
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Author: P. N. Preston
Publisher: John Wiley & Sons
ISBN: 0470188677
Category : Science
Languages : en
Pages : 702

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The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Author: Ana Escribano Cuesta
Publisher: Springer Science & Business Media
ISBN: 3319007025
Category : Science
Languages : en
Pages : 202

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Ana Escribano Cuesta's thesis presents a detailed study of the inter- and intramolecular reactions of carbonyl compounds with 1,6-enynes using gold (I) complexes. An important part of the work involved streamlining the variables that allow the selective synthesis of different products such as tricyclic compounds, dihydropyrans, 1,3-dienes or cyclobutenes. The second chapter highlights the importance and difficulties in synthesising a cyclobutene subunit and the author includes a detailed description of how the products were prepared. The final chapter outlines the synthesis of lundurines using methodology developed by the author's research group for intramolecular gold-catalyzed cyclization of indoles with alkynes. The lundurine products developed in this work show significant in vitro cytoxicity toward B16 melanoma cells. The work in this thesis has led to a number of publications in high-profile chemistry journals.