Author: Norman Graciano Berríos-PenãPublisher:
ISBN:
Category :
Languages : en
Pages : 344
Book Description
Synthesis of Heterocycles Via Palladium-catalyzed Heteroannulation of Dienes
Author: Norman Graciano Berríos-PenãPublisher:
ISBN:
Category :
Languages : en
Pages : 344
Book Description
Synthesis of Heterocycles Via Palladium-catalized Heteroannulation of Dienes
Author: Norman Graciano Berrios-penaPublisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Synthesis of Heterocycles via Metal-Catalyzed Reactions that Generate One or More Carbon-Heteroatom Bonds
Author: John P. WolfePublisher: Springer
ISBN: 3642388809
Category : Science
Languages : en
Pages : 276
Book Description
Synthesis of Saturated Heterocycles via Metal-Catalyzed Alkene Carboamination or Carboalkoxylation Reactions, by John P. Wolfe Synthesis of Saturated Heterocycles via Metal-Catalyzed Alkene Diamination, Aminoalkoxylation, or Dialkoxylation Reactions, by Sherry R. Chemler Synthesis of Heterocycles via Metal-Catalyzed Wacker-Type Oxidative Cyclization Reactions of Alkoxy- or Amino-Alkenes, by Wanbin Zhang Synthesis of Saturated Heterocycles via Metal-Catalyzed Hydroamination or Hydroalkoxylation Reactions, by Lisa D. Julian Synthesis of Saturated Heterocycles via Metal-Catalyzed Allylic Alkylation Reactions, by Aaron Aponick Synthesis of Heterocycles via Metal-Catalyzed Cascade/Domino Reactions that Generate a C–N or C–O Bond, by Mark Lautens Synthesis of Saturated Heterocycles via Metal-Catalyzed Formal Cycloaddition Reactions that Generate a C–N or C–O Bond, by Jerome Waser
Synthesis of Heterocycles Via Palladium-catalyzed Coupling of Vinylic Halides and Functionally-substituted Alkenes
Author: Hoseok YangPalladium Assisted Synthesis of Heterocycles
Author: Navjeet KaurPublisher: CRC Press
ISBN: 1351242598
Category : Medical
Languages : en
Pages : 482
Book Description
This book is a compilation of the recent applications of palladium catalysts in organic synthesis. The book demonstrates that it is a highly dynamic research field. This methodology has emerged as a powerful tool for the efficient and chemoselective synthesis of heterocyclic molecules. In the past few years, several strategies have been pointed out to pursue more efficient, sustainable, and environment friendly chemical processes. Among those strategies, catalysis and the design of new processes that avoid the use of toxic reagents have been the focus of intense research.
Heterocycles from Double-Functionalized Arenes
Author: Xiao-Feng WuPublisher: Royal Society of Chemistry
ISBN: 1782621369
Category : Science
Languages : en
Pages : 315
Book Description
An introduction to transition metal catalyzed coupling reactions of double-functionalized arenes in heterocycle synthesis.
Noble Metal Noble Value: Ru-, Rh-, Pd-catalyzed Heterocycle Synthesis
Author: Xiao-feng WuPublisher: World Scientific
ISBN: 1783269251
Category : Science
Languages : en
Pages : 390
Book Description
Heterocyclic chemistry constitutes the largest branch of chemistry, covering almost two-thirds of literature in the field. In addition, around 90% of naturally-occurring molecules have heterocycles as their core structure. Therefore, as a central part of organic chemistry, the discovery of new methodologies in synthesizing heterocyclic compounds is essential to their continued application and development. Transition metal catalysts offer a low cost and often low toxicity pathway for heterocycles synthesis, while the use of noble metals represents an alternative form of experimentation which is discussed in the book.Noble Metals, Noble Value provides the first comprehensive analysis of the applications of the noble metals of ruthenium (Ru), rhodium (Rh) and palladium (Pd) catalysts in heterocycles synthesis. Pairs of chapters are dedicated to summarizing each of the metals when applied to either five- or six-membered heterocyclic syntheses. An introduction to the importance of heterocycles and possible procedures for the preparation of heterocyclic compounds is also given.With up to date research and findings, this review is excellently suited to academics and professionals in the field of chemistry, with a particular focus on the specialities of biological, catalytic and organic chemistry.
Synthesis of Functionalized Heterocycles Via Palladium Catalyzed Cross-coupling Reactions
Author: Huy Hoang DoSynthesis and Elaboration of Heterocycles Via Palladium-catalyzed C-H Functionalization
Author: Maria GerellePublisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Chapter 1 is a brief literature review of the most recent progress in the area of C-H functionalization via palladium catalysis. This covers the functionalization of electron deficient arenes and heterocycles with alkenyl and alkyl halides both using inter- and intra-molecular reactions. The chapter also contains an overview of recent work from the Willis group. Chapter 2 presents the functionalization of electron deficient arenes and alkenyl bromides using palladium catalysis (Scheme 1), as well as the use of statistical analysis software for optimizing the cross-coupling reaction. Scheme 1: Functionalization of electron deficient arenes using palladium catalysis Chapter 3 describes the cross-coupling of substituted benzoxazoles, benzothiazole and benzimidazole with a range of alkenyl iodides using palladium catalysis (Scheme 2). The reaction can tolerate both (E) and (Z) disubstituted alkenes and tri-substituted alkenyl iodides, with retention of the double bond geometry. 1 x =0, S, NMe - 14 examples 25-99% yield i Scheme 2: Cross-coupling using benzoxazoles, benzothiazole and benzimidazole with alkenyl iodides Chapter 4 details the synthesis of sultams via an intramolecular functionalization using palladium catalysis. The chapter covers the optimization of the starting material synthesis as well as the cross-coupling reaction. We can access the sulfonamides from cyc1ohexenone and were able to incorporate a large range of substitution patterns (Scheme 3). Scheme 3: Synthesis ofsultams from cyclohexenone Finally, Chapter 5 contains all the experimental details, general considerations and compound data. All the NMR spectra of novel compounds can be found in the appendix. 2.
Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles
Author: Hyung YoonPublisher: Springer Nature
ISBN: 3030540774
Category : Science
Languages : en
Pages : 236
Book Description
This book presents Pd- and Ni-catalyzed transformations generating functionalized heterocycles. Transition metal catalysis is at the forefront of synthetic organic chemistry since it offers new and powerful methods to forge carbon–carbon bonds in high atom- and step-economy. In Chapter 1, the author describes a Pd- and Ni-catalyzed cycloisomerization of aryl iodides to alkyl iodides, known as carboiodination. In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination. It then discusses Ni-catalyzed reactions to generate oxindoles and an enantioselective variant employing a dual ligand system. Chapter 2 introduces readers to a Pd-catalyzed diastereoselective anion-capture cascade. It also examines diastereoselective Pd-catalyzed aryl cyanation to synthesize alkyl nitriles, a method that generates high yields of borylated chromans as a single diastereomer, and highlights its synthetic utility. Lastly, Chapter 3 presents a Pd-catalyzed domino process harnessing carbopalladation, C–H activation and π-system insertion (benzynes and alkynes) to generate spirocycles. It also describes the mechanistic studies performed on these reactions.