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Synthesis of Aminoglycosides and Amino-C-glycosides from Glycals

Synthesis of Aminoglycosides and Amino-C-glycosides from Glycals PDF Author: Russell Scott Dahl
Publisher:
ISBN:
Category :
Languages : en
Pages : 402

Book Description


Synthesis of Aminoglycosides and Amino-C-glycosides from Glycals

Synthesis of Aminoglycosides and Amino-C-glycosides from Glycals PDF Author: Russell Scott Dahl
Publisher:
ISBN:
Category :
Languages : en
Pages : 402

Book Description


Total Synthesis of Aminomethyl C-glycosides

Total Synthesis of Aminomethyl C-glycosides PDF Author: Dmitriy Gremyachinskiy
Publisher:
ISBN:
Category : Amino compounds
Languages : en
Pages : 232

Book Description


Dissertation Abstracts International

Dissertation Abstracts International PDF Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 860

Book Description


Synthesis and Characterization of Glycosides

Synthesis and Characterization of Glycosides PDF Author: Marco Brito-Arias
Publisher: Springer Science & Business Media
ISBN: 0387707921
Category : Science
Languages : en
Pages : 362

Book Description
This book contains the best known approaches for preparing the main types of glycosides in a short and comprehensive study. It also includes synthetic pathways of challenging glycosides known as antiviral or antineoplasic drugs, or synthetic substrates used for enzymatic detection including those used as substrates for detection of gene markers in plant biotechnology. Special attention is made on the structural characterization, providing the basic tools for the structural assignment through NMR, X-Ray and mass spectra techniques. Some of the chapters cover strategies for preparation of antiviral and antineoplasic drugs included in a drug design course.

Handbook of Chemical Glycosylation

Handbook of Chemical Glycosylation PDF Author: Alexei V. Demchenko
Publisher: John Wiley & Sons
ISBN: 3527621652
Category : Science
Languages : en
Pages : 524

Book Description
Since carbohydrate oligomers are still a challenge in synthetic chemistry, this book on recent developments fulfils a great need. Covering the chemistry necessary to synthesize exact copies of these structures, top authors from all around the world comprehensively deal with synthesis from anomeric halides, from miscellaneous glycosyl donors, and by indirect and special methods, as well as 1-oxygen-and 1-sulfur-substituted derivatives. They demonstrate the best approach for the stereoselective formation of the intermonomeric bond, making this essential reading for every biochemist working in biosynthesis, the exploration of biopathways and vaccines.

Advances in Carbohydrate Chemistry and Biochemistry

Advances in Carbohydrate Chemistry and Biochemistry PDF Author:
Publisher: Elsevier
ISBN: 0080545866
Category : Science
Languages : en
Pages : 473

Book Description
Since its inception in 1945, Advances in Carbohydrate Chemistry and Biochemistry has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. - High quality comprehensive reviews covering all aspects of carbohydrate chemistry

Glycochemical Synthesis

Glycochemical Synthesis PDF Author: Shang-Cheng Hung
Publisher: John Wiley & Sons
ISBN: 1118299841
Category : Science
Languages : en
Pages : 574

Book Description
This book is a comprehensive and concise review on principles, strategies, and crucial advances in glycochemistry. It focuses on synthesis and practical applications and emphasizes state-of-the-art approaches to the assembly and design of sugars. • Provides detailed discussion on specific topics like oligosaccharide assembly and design of sugars, techniques in glycoconjugate preparation, multivalency, and carbohydrate-based drug design • Uses notable examples, like solution-based one-pot methods and automated methods for sugar assembly, to illustrate important concepts and advances in a rapidly emerging field • Discusses practical applications of carbohydrates, like medicine, therapeutics, drug and vaccine development

Selective Glycosylations

Selective Glycosylations PDF Author: Clay S. Bennett
Publisher: John Wiley & Sons
ISBN: 3527696229
Category : Science
Languages : en
Pages : 398

Book Description
A comprehensive summary of novel approaches to the stereoselective construction of glycosidic linkages, covering modern glycosylation methods and their use and application in natural product synthesis and drug discovery. Clearly divided into five sections, the first describes recent advances in classical methodologies in carbohydrate chemistry, while the second goes on to deal with newer chemistries developed to control selectivity in glycosylation reactions. Section three is devoted to selective glycosylation reactions that rely on the use of catalytic promoters. Section four describes modern approaches for controlling regioselectivity in carbohydrate synthesis. The final section focuses on new developments in the construction of "unusual" sugars and is rounded off by a presentation of modern procedures for the construction of glycosylated natural products. By providing the latest advances in glycosylation as well as information on mechanistic aspects of the reaction, this is an invaluable reference for both specialists and beginners in this booming interdisciplinary field that includes carbohydrate chemistry, organic synthesis, catalysis, and biochemistry.

Organic Azides

Organic Azides PDF Author: Stefan Bräse
Publisher: John Wiley & Sons
ISBN: 0470519983
Category : Science
Languages : en
Pages : 537

Book Description
Most current state-of-the-art overview of this important class of compounds, encompassing many new and emerging applications The number of articles on organic azides continues to increase tremendously; on average, there are more than 1000 new publications a year Covers basic chemistry as well as state-of-the-art applications in life science and materials science World-ranked authors describe their own research in the wider context of azide chemistry Includes a chapter on safe synthesis and handling (azides can decompose explosively)

C-Furanosides

C-Furanosides PDF Author: Peter Goekjian
Publisher: Academic Press
ISBN: 012803789X
Category : Science
Languages : en
Pages : 796

Book Description
Carbon analogs of carbohydrates, dubbed C-glycosides, have remained an important and interesting class of mimetics, be it in natural product synthesis, for pharmacological applications, as conformational probes, or for biological studies. C-Furanosides: Synthesis and Stereochemistry provides a much-needed overview of synthetic and stereochemical principles for C-furanosides: analogs of a 5-membered ring carbohydrate glycoside (furanoside), in which the anomeric oxygen has been replaced with a carbon. While our understanding of conformational behavior and of stereoselective synthesis in 6-membered ring compounds is quite good, our ability to predict the conformation of 5-membered ring compounds, or to predict the stereochemical outcome of a given reaction, remains anecdotal. Through a comprehensive review of literature approaches to the different C-furanoside stereoisomers, as well as an interpretation of the outcome in terms of a reasonable number of stereochemical models, C-Furanosides: Synthesis and Stereochemistry enables the reader to determine the best approach to a particular C-glycoside compound, and also hopes to provide a certain level of rationalization and predictability for the synthesis of new systems. - Provides a comprehensive review of the growing literature in C-furanosides - Enables readers to choose the most convenient approach to access a defined target in natural products synthesis or pharmacology and make reasonable predictions for the stereochemical outcome in unpublished cases - Explores the various rational models for stereochemical analysis of furanoside reactivity, with a clear distinction made between physical chemical mechanisms and stereochemical models