Author: Kelly MiltonPublisher:
ISBN:
Category : Silica
Languages : en
Pages : 216
Book Description
Synthesis of Accessible Aromatic Amine-functionalized Mesoporous Silica
Author: Kelly MiltonDirect Synthesis of Accessible Primary Amine-functionalized Mesoporous Silica
Author: Stephen SoukasenePublisher:
ISBN:
Category : Silica
Languages : en
Pages : 112
Book Description
Synthesis and Optimization of Surface Functionalized Mesoporous Silica Nanoparticles for Bioconjugation Platforms
Author: Anand Srinath GopalanPublisher:
ISBN: 9781369174052
Category :
Languages : en
Pages : 42
Book Description
A large amount of emphasis has been dedicated in recent years to introduce nanoparticles as a viable candidate for targeted therapies. In comparison to other candidates, mesoporous silica nanoparticles have the advantages of being biocompatible, easy to produce, and have the ability to prove to be a theranostic platform. To better study the specific targeting of diseased cells, adhesion studies of drug carrying bioconjugation constructs in fluid environments is required. The goal of this project was to develop a platform based on mesoporous silica nanoparticles that will be used for future multivalent adhesion studies. Specifically, mesoporous silica nanoparticles were synthesized with various sizes and aspect ratios, containing fluorescent dye to enable tracking studies, and with surface treatments that optimized stability and introduced primary-amine functional groups to facilitate attachment with targeted proteins and biomarkers. The effects of various parameters such as solvents, washing methods, secondary modifications and difference in concentrations of the starting materials for the synthesis mixture on the nanoparticles were studied in detail in this thesis. A portion of the study is also dedicated to optimizing a washing procedure to stabilize the particles in an aqueous medium in order to facilitate further modifications. The results of the work in this project can be utilized to provide a platform for further assays in flow chambers after bioconjugation with targeting proteins through orthogonal chemistries to study the adhesion properties in much greater detail.
Synthesis and Characterization of Functionalized Mesoporous Silica for the Remediation of Heavy Metals from Aqueous Solution
Author: Robert M. LandisDesign, Synthesis and Characterization of Functionalized Mesoporous Silica Nanospheres for Biomedical Applications
Author: 林芝宇Synthesis of Functionalized Mesoporous Silica for Selective Extraction of Rare Earth Elements
Author: Yimu HuPublisher:
ISBN:
Category :
Languages : en
Pages : 225
Book Description
Les éléments terres rares (ETRs) sont un groupe de 17 métaux aux propriétés voisines comprenant le scandium, l'yttrium, et les 15 lanthanides. Ces éléments sont indispensables à la production de nombreux appareils de haute technologie et incontournables dans le développement des énergies durables. Contrairement à ce que suggère leur appellation, les ETRs sont assez répandus dans la croûte terrestre, alors que leur extraction, à savoir l'extraction liquide-liquide (ELL), est extrêmement difficile, coûteuse et surtout polluante. Afin de fournir une alternative aux procédés industriels, les matériaux mésoporeux à base de silice ont été sollicités à titre d'adsorbant dans l'extraction sur phase solide. Ces matériaux structurés sont intéressants pour l'adsorption d'ETRs puisqu'il est possible d'en modifier simplement la surface avec des ligands adaptés pour l'application voulue. Dans cette thèse, deux séries de ligands à base de structure phthaloyl diamide (PA) et phenylenedioxy diamide (PDDA) ont été synthétisés et greffés sur la surface de matériaux mésoporeux à base de silice KIT-6. Il s'avère, aux vues des résultats obtenus, que ces adsorbants permettent d'extraire sélectivement les éléments de taille différente selon le bite angle du ligand greffé, tandis que la sélectivité n'a pas été observée pour ses analogues homogènes sous la condition de l'extraction liquide-liquide. En plus, les réseaux bimodaux monolithiques qui présentent simultanément des mésopores ainsi que des macropores (pores > 50 nm) sont avantageux, surtout pour l'extraction en conditions dynamiques (en colonne). Les mésopores permettent d'augmenter la surface spécifique du matériau ainsi la surface de contact entre l'agent actif et la solution. Les macropores, quant à eux, améliorent la capacité de transport des fluides, permettant d'éviter l'accumulation des produits et d'ainsi de bloquer les sites actifs. Dans cette étude, des monolithes à base de silice de taille de quelques centimètres ont été obtenus. Après la fonctionnalisation avec le ligand diglycolamide (DGA), les monolithes révèlent des profils de sélectivité exceptionnels envers le Th(IV) dans l'extraction en colonne. La technique concernant les matériaux à empreinte ionique rend possible une sélectivité spécifique. Dans ce cas-ci, la synthèse de matériaux a été réalisée par la co-condensation entre l'organosilane et le précurseur siliceux en présence d'ion Dy3+. Par la suite, la molécule empreinte est enlevée, laissant derrière elle les sites de liaisons et une cavité ayant la forme et la taille du Dy3+. Ainsi, les silices empreintes sont capables de séparer spécifiquement et sélectivement l'ion Dy3+. Dans tous les trois systèmes présentés ici, ces matériaux peuvent aussi être considérés comme étant intéressants pour les applications industrielles, tant en terme de la stabilité sous les conditions d'adsorption testées, que de la sélectivité et de la capacité d'adsorption envers les échantillons de déchets minéraux.
Synthesis and Characterization of Aminotroponiminate-zinc Functionalized Mesoporous Silica and Exfoliated Fluorosilica Nanomaterials as Efficient Catalysts
Author: Cole Tyler DuncanPublisher:
ISBN: 9781124392561
Category : Catalysts
Languages : en
Pages : 245
Book Description
Soft-templating Synthesis of Mesoporous Silica-based Materials for Environmental Applications
Author: Chamila Asanka GunathilakePublisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Dissertation research is mainly focus on: 1) the development of mesoporous silica materials with organic pendant and bridging groups (isocyanurate, amidoxime, benzene) and incorporated metal (aluminum, zirconium, calcium, and magnesium) species for high temperature carbon dioxide (CO2) sorption, 2) phosphorous-hydroxy functionalized mesoporous silica materials for water treatment, and 3) amidoxime-modified ordered mesoporous silica materials for uranium sorption under seawater conditions. The goal is to design composite materials for environmental applications with desired porosity, surface area, and functionality by selecting proper metal oxide precursors, organosilanes, tetraethylorthosilicate, (TEOS), and block copolymer templates and by adjusting synthesis conditions.The first part of dissertation presents experimental studies on the merge of aluminum, zirconium, calcium, and magnesium oxides with mesoporous silica materials containing organic pendant (amidoxime) and bridging groups (isocyanurate, benzene) to obtain composite sorbents for CO2 sorption at ambient (0-25 oC) and elevated(60-120 oC) temperatures. These studies indicate that the aforementioned composite sorbents are fairly good for CO2 capture at 25 oC via physisorption mechanism and show a remarkably high affinity toward CO2 chemisorption at 60- 120 oC. The second part of dissertation is devoted to silica-based materials with organic functionalities for removal of heavy metal ions such as lead from contaminated water and for recovery of metal ions such as uranium from seawater. First, ordered mesoporous organosilica (OMO) materials with diethylphosphatoethyl and hydroxyphosphatoethyl surface groups were examined for Pb2+ adsorption and showed unprecedented adsorption capacities up to 272 mg/g and 202 mg/g, respectively However, the amidoxime-modified OMO materials were explored for uranium extraction under seawater conditions and showed remarkable capacities reaching 57 mg of uranium per gram of adsorbent.
Synthesis & Characterization of Sulfo-Functionalized Nanoporous Silica
Author: Fei-Yee YeohPublisher: LAP Lambert Academic Publishing
ISBN: 9783848483419
Category :
Languages : en
Pages : 116
Book Description
This book is an edited collection of authors papers regarding research on sulfo-functionalized nanoporous silica, published with various renowned journals. It provides in-depth scientific research findings on synthesis and characterization of sulfo-functionalized nanoporous silica typically with pore sizes in mesopores and micropores range. Detailed synthesis and characterization techniques are recorded with insightful discussion and findings. The use of ammonia adsorption microcalometry for characterization and application of such materials could also be found in the book. Besides synthesis with conventional route, the author also found a novel route to produce this material, which is noted in this book as Facile Synthesis of Sulfo functionalized mesoporous silica. This book would be helpful in giving a comprehensive understanding to undergraduate and postgraduate students, as well as academics and researchers who are involved in materials sciences and chemical engineering research.
Organically Modified Mesoporous Silica as a Support for Synthesis and Catalysis
Author: Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Mesoporous silicates are excellent materials for supported catalysis due to their ease of functionalization, tunable pore size and high surface areas. Mesoporous silicates have been utilized in a variety of applications such as drug delivery scaffolds and catalyst supports. Functionalization of the surface can be achieved by either grafting of alkoxy silanes or co-condensation of the organosilane with the inorganic silica source. My research in this area can be divided into two components. In the first, we address the significant issue of metal contamination after reactions that are catalyzed by transition metals. In the second, we examine the design of new catalysts based on organic/inorganic composites. Ruthenium catalyzed processes such as olefin metathesis or asymmetric hydrogenation, are often underutilized due to the difficulty of removing the ruthenium by-products. Attempts to remove ruthenium involve treating the solution with a scavenging reagent followed by silica chromatography. Often these scavenging agents are expensive phosphines or toxic agents like lead tetra-acetate. SBA-15 functionalized with aminopropyl triethoxysilane displays a high affinity for ruthenium. Furthermore, it can be utilized to remove ruthenium by-products from olefin metathesis or hydrogenation reactions without the need for silica chromatography. We have also prepared sulfur-functionalized mesoporous silicates that have a high affinity for palladium. The materials after loading prove to be active catalysts for a variety of palladium catalyzed processes such as Suzuki-Miyaura and Sonogashira couplings. The catalysts are recyclable with moderate loss of activity and structure, depending on the method of incorporation of the thiol. We have characterized the as-synthesized and used catalysts by nitrogen sorption, TEM, X-ray photoelectron spectroscopy (XPS) and a variety of homogeneity tests were performed on the catalysts. Periodic mesoporous organosilicates (PMOs) are a well known cl.