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Author: Atta-ur-Rahman Publisher: CRC Press ISBN: 1135287228 Category : Medical Languages : en Pages : 214
Book Description
The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassa
Author: Atta-ur-Rahman Publisher: CRC Press ISBN: 1135287228 Category : Medical Languages : en Pages : 214
Book Description
The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassa
Author: Kenneth D. Karlin Publisher: Wiley-Interscience ISBN: 9780471463702 Category : Science Languages : en Pages : 612
Book Description
The cutting edge of scientific reporting . . . PROGRESS in Inorganic Chemistry Nowhere is creative scientific talent busier than in the world of inorganic chemistry experimentation. Progress in Inorganic Chemistry continues in its tradition of being the most respected avenue for exchanging innovative research. This series provides inorganic chemists and materials scientists with a forum for critical, authoritative evaluations of advances in every area of the discipline. With contributions from internationally renowned chemists, this latest volume offers an in-depth, far-ranging examination of the changing face of the field, providing a tantalizing glimpse of the emerging state of the science. "This series is distinguished not only by its scope and breadth, but also by the depth and quality of the reviews." -Journal of the American Chemical Society "[This series] has won a deservedly honored place on the bookshelf of the chemist attempting to keep afloat in the torrent of original papers on inorganic chemistry." -Chemistry in Britain CONTENTS OF VOLUME 53 * Main Group Dithiocarbamate Complex (Peter J. Heard) * Transition Metal Dithiocarbamates-1978-2003 (Graeme Hogarth)
Author: Marcel Gielen Publisher: John Wiley & Sons ISBN: 0470864044 Category : Science Languages : en Pages : 638
Book Description
There are an astonishing number and variety of roles that metals play in contemporary medicine. This book contains information on the medicinal uses of inorganics, that is, of elements such as boron, lithium, selenium, to name a few, as well as metal-containing species. In keeping with the notion that healthy mammals rely on (bio-essential) metals for the normal functioning of approximately a third of their proteins and enzymes, a large number of drugs are metal-based and considerable effort is being devoted to developing both second- and third-generation drugs as well as generating novel metal-based drugs. While there is no doubt that there is an emphasis on 'Metallotherapeutics' throughout the volume, the use of metals in medicine is not restricted to metal-based drugs. The following are also covered: non-invasive radiopharmaceuticals Magnetic Resonance Imaging (MRI) mineral supplements From the foregoing and, more importantly, from the contents of the various Chapters, the reader will gain an appreciation of the very real role metal-based drugs play in modern medicine and of the considerable effort being devoted to the development of novel complexes with greater efficacy as therapeutic and diagnostic agents.
Author: Marcel Gielen Publisher: John Wiley & Sons ISBN: 0470758082 Category : Science Languages : en Pages : 752
Book Description
Tin chemistry retains a place in contemporary science as an important element owing to its wide range of applications. New and exciting research is being generated on an annual basis from all parts of the world – the study of tin and its compounds attracts considerable interest from a range of perspectives such as organic synthesis, medicine, materials chemistry, catalysis and environment. Tin Chemistry – Fundamentals, Frontiers and Applications collects, in one comprehensive volume, authoritative and concise snapshots of modern tin chemistry in a full range of applications. Over forty of the leading tin chemistry experts have contributed reviews in six themes: fundamentals in tin chemistry materials chemistry and structural chemistry of tin compounds medicinal and biocidal applications of tin compounds tin in the environment tin in organic synthesis tin in catalysis Tin Chemistry – Fundamentals, Frontiers and Applications is an essential overview of modern perspectives on this important element for the specialist and non-specialist alike. It will promote cross-disciplinary interactions and at the same time be an essential teaching resource for advanced university classes.
Author: Alessandra Pagliarani Publisher: Bentham Science Publishers ISBN: 1608052656 Category : Science Languages : en Pages : 215
Book Description
Organotins are widespread contaminants especially of water environments. Their chemically versatile structure makes organotin compounds able to bind to a variety of biomolecules thus widely affecting biological functions. Trisubstituted molecules, namely tributyltin (TBT) and triphenyltin (TPhT), have been widely employed in antifouling paints and are also exploited as plastic stabilizers that unfortunately cause harmful biological effects. Persistent bioaccumulation has resulted in organotins becoming a significant environmental threat. Chapter by chapter, the biological and biochemical effec.
Author: P.J. Smith Publisher: Springer Science & Business Media ISBN: 9401149380 Category : Science Languages : en Pages : 592
Book Description
In common with the editor of the first edition, my own personal involvement with tin chemistry began when I had the privilege of studying for a PhD degree under the supervision of Professor Alwyn G. Davies FRS at University College London (UCL) almost exactly 30 years ago. Then, following 21 years' service with the International Tin Research Institute, it was a great pleasure for me when the wheel turned full circle and, in 1994, Alwyn - now an Emeritus Professor - asked me to return to UCL as an Honorary Research Fellow in the Chemistry Department. One of my first tasks was when I received an invitation from Blackie A&P to edit the second edition of the Chemistry of Tin, which I was delighted to accept, since it enabled me to continued my life-long interest in tin chemistry and to maintain contact with my former friends and colleagues, many of whom have contributed to this book.
Author: B.I. Kharisov Publisher: Elsevier ISBN: 0128110627 Category : Science Languages : en Pages : 470
Book Description
Direct Synthesis of Metal Complexes provides in-depth coverage of the direct synthesis of coordination and organometallic compounds. The work is primarily organized by methods, but also covers highly relevant complexes, such as metal-polymer coordination compounds. This updated reference discusses recent developments in cryosynthesis, electrosynthesis, and tribosynthesis (popular as it doesn't require organic solvents), with special attention paid to 'greener' methodologies and approaches. Additionally, the book describes physical methods of zero-valent metal interaction with organic matter, including sputtering, ultrasonic treatment and synthesis in ionic liquids. The book presents completely new content as a follow-up to the 1999 Elsevier Science publication Direct Synthesis of Coordination and Organometallic Compounds that was edited by Dr. Garnovskii and Dr. Kharisov. - Covers current methods and techniques of metal interactions with organic media leading to metal chelates, adducts, di- and polymetallic complexes, metal-containing macrocycles, supported coordination compounds (i.e., metal complexes on carbon nanotubes), and more - Describes reactivities of distinct forms of elemental metals (powders, sheets, nanoparticles (including a host of less-common metal nanostructures) with organic phase (liquid, solid and gaseous) and water - Includes experimental procedures, with examples of direct synthesis, at the end of each chapter
Author: Boris Kharisov Publisher: Elsevier ISBN: 012821967X Category : Science Languages : en Pages : 978
Book Description
Modern techniques to produce nanoparticles, nanomaterials, and nanocomposites are based on approaches that frequently involve high costs, inefficiencies, and negative environmental impacts. As such, there has been a real drive to develop and apply approaches that are more efficient and benign. The Handbook of Greener Synthesis of Nanomaterials and Compounds provides a comprehensive review of developments in this field, combining foundational green and nano-chemistry with the key information researchers need to assess, select and apply the most appropriate green synthesis approaches to their own work.Volume 1: Fundamental Principles and Methods provides a clear introduction to the fundamentals of green synthesis that places synthesis in the context of green chemistry. Beginning with a discussion of key greener physical and chemical methods for synthesis, including ultrasound, microwave and mechanochemistry methods, the book goes on to explore biological methods, including biosynthesis, green nanoformation, and virus-assisted methods. - Discusses synthesis in the context of the principles of green chemistry - Highlights both traditional and innovative technologies for the synthesis of nanomaterials and related composites under green chemistry conditions - Reflects on the current and potential applications of natural products chemistry in synthesis
Author: Pallavi Jain Publisher: CRC Press ISBN: 1000865460 Category : Science Languages : en Pages : 360
Book Description
Coordination compounds have been well-known for their wide variety of applications for over a century, as well as enhancing the researcher’s interest and concern in evaluating their action mechanism. It is certainly one of the most intensely discussed research topics. Coordination compounds involve different metal-ion-ligand phenomenon. The involved metal ions play a significant role in structural association and functioning of several processes in the genetic and metabolism system. In recent years, Schiff base ligands have gained significant interest and received a keen interest of many researchers. Schiff’s base ligands have been recognized to hold a wide variety of biological and medicinal activities due to the presence of donor atoms. They have proved exceptional pharmalogical actions such as antimicrobial, anti-tuberclosis, antiplatelet, antidiabetic, antiarthritis, antioxidant, anti-inflammatory, anticancer, antiviral, antimalarial, and analgesic. These biologically active Schiff base ligands have also been shown to inhibit enzyme mobilization and, when bound to a metal ion, exhibit enhanced biological activity, making them useful in a number of fields. As a result, metal complexes of Schiff base ligands are gaining popularity due to their unique properties and functionalities. Schiff base complex-based research for educational and industrial purposes is booming, and the number of publications is gradually increasing. Despite these interests, there is currently no detailed book on Schiff base metal complexes that covers the structures, biological activities, and other non-biological perspectives. This book delves into the structures of Schiff base metal complexes, which are critical in assessing the biological viability of any complex. It also highlights their biological significance in pharma and drug discovery like antibacterial, antifungal, anticancer, anti-inflammatory, anti-arthritis, anti-diabetic, antioxidants, anti-proliferative, antitumor, anticancer, antiviral. The fundamentals of metal complexes are described, as well as an up-to-date outline of developments in synthesis, characterization methods, properties- chemical, thermal, optical, structural, and applications. This book also discusses the other applications of Schiff base metal complexes: as sensor (luminescent, electrochemical, and biosensor), as pigments in dying and paint industries, as photocatalyst to improve the degradation rate. Features : This book would be useful for academia, researchers and engineers working in the area of Schiff base and their metal complexes. This book will give an in-depth account of the properties of Schiff base and their metal complexes. This book will discuss the details of synthesis methods for Schiff base and their metal complexes. This book will cover emerging trends in the use of Schiff base metal complexes in the industry. This book will provide an overview of the wider biological applications of Schiff base metal complexes
Author: Atta-ur-Rahman
Author: Atta-ur-Rahman
Author: Kenneth D. Karlin
Author: Marcel Gielen
Author: Marcel Gielen
Author: Alessandra Pagliarani
Author: P.J. Smith
Author: B.I. Kharisov
Author: Koji Nakanishi
Author: Boris Kharisov
Author: Pallavi Jain