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Copper-Mediated Cross-Coupling Reactions

Copper-Mediated Cross-Coupling Reactions PDF Author: Gwilherm Evano
Publisher: John Wiley & Sons
ISBN: 1118060458
Category : Science
Languages : en
Pages : 851

Book Description
Providing comprehensive insight into the use of copper in cross-coupling reactions, Copper-Mediated Cross-Coupling Reactions provides a complete up-to-date collection of the available reactions and catalytic systems for the formation of carbon-heteroatom and carbon-carbon bonds. This essential reference covers a broad scope of copper-mediated reactions, their variations, key advances, improvements, and an array of academic and industrial applications that have revolutionized the field of organic synthesis. The text also discusses the mechanism of these transformations, the use of copper as cost-efficient alternative to palladium, as well as recently developed methods for conducting copper-mediated reactions with supported catalysts.

Copper-Mediated Cross-Coupling Reactions

Copper-Mediated Cross-Coupling Reactions PDF Author: Gwilherm Evano
Publisher: John Wiley & Sons
ISBN: 1118060458
Category : Science
Languages : en
Pages : 851

Book Description
Providing comprehensive insight into the use of copper in cross-coupling reactions, Copper-Mediated Cross-Coupling Reactions provides a complete up-to-date collection of the available reactions and catalytic systems for the formation of carbon-heteroatom and carbon-carbon bonds. This essential reference covers a broad scope of copper-mediated reactions, their variations, key advances, improvements, and an array of academic and industrial applications that have revolutionized the field of organic synthesis. The text also discusses the mechanism of these transformations, the use of copper as cost-efficient alternative to palladium, as well as recently developed methods for conducting copper-mediated reactions with supported catalysts.

Modern Carbonylation Methods

Modern Carbonylation Methods PDF Author: László Kollár
Publisher: John Wiley & Sons
ISBN: 3527621555
Category : Science
Languages : en
Pages : 383

Book Description
Comprehensively covering modern carbonylation chemistry, this book is an indispensable companion for all synthetic chemists working in industry and academia. This monograph contains everything there is to know from recent advances in the investigation of carbonylation catalysts, via coordination chemistry to the synthetic application of transition metal catalyzed carbonylations.

Practical Medicinal Chemistry with Macrocycles

Practical Medicinal Chemistry with Macrocycles PDF Author: Eric Marsault
Publisher: John Wiley & Sons
ISBN: 1119092566
Category : Science
Languages : en
Pages : 617

Book Description
Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations

Handbook of Organopalladium Chemistry for Organic Synthesis

Handbook of Organopalladium Chemistry for Organic Synthesis PDF Author: Ei-ichi Negishi
Publisher: John Wiley & Sons
ISBN: 0471473812
Category : Science
Languages : en
Pages : 1657

Book Description
Organized to provide maximum utility to the bench synthetic chemist. The editor is well-known for his work in exploring, developing, and applying organopalladium chemistry. Contributors include over 24 world authorities in the field.

Transition Metal Catalyzed Carbonylation Reactions

Transition Metal Catalyzed Carbonylation Reactions PDF Author: Matthias Beller
Publisher: Springer Science & Business Media
ISBN: 3642390161
Category : Science
Languages : en
Pages : 234

Book Description
Transition Metal Catalyzed Carbonylation Reactions is a comprehensive monograph focusing on carbon monoxide usage. This book provides students and researchers in organic synthesis with a detailed discussion of carbonylation from the basics through to applications. The authors have structured the book around the types of reactions, based on the different nucleophiles involved. Scientists working in carbonylation or with carbon monoxide, as well as teachers of organic synthesis can use this book to become familiar with this important area of organic chemistry.

The Stille Reaction

The Stille Reaction PDF Author: Vittorio Farina
Publisher: John Wiley & Sons
ISBN: 9780471312734
Category : Science
Languages : en
Pages : 676

Book Description
Die Stille-Reaktion ist eine der sehr wenigen Reaktionen, in denen unter milden Bedingungen Kohlenstoff-Kohlenstoff-Bindungen geknüpft werden können. Man verwendet die Reaktion häufig in der Synthese komplizierter Moleküle zur Verknüpfung größerer Molekülbausteine. Die Autoren diskutieren vom präparativen Standpunkt aus Grenzen, Einflüsse, strukturelle Effekte und die Wahl der geeigneten Reaktionsbedingungen. Mit ausführlichen Vorschriften und vielen Beispielen. (11/98)

Sustainable Synthesis of Pharmaceuticals

Sustainable Synthesis of Pharmaceuticals PDF Author: Mariette M. Pereira
Publisher: Royal Society of Chemistry
ISBN: 1788010655
Category : Business & Economics
Languages : en
Pages : 300

Book Description


Naturally Occurring Organohalogen Compounds - A Comprehensive Update

Naturally Occurring Organohalogen Compounds - A Comprehensive Update PDF Author: Gordon W. Gribble
Publisher: Springer
ISBN: 9783709110997
Category : Science
Languages : en
Pages : 613

Book Description
Despite the long association of organohalogen compounds with human activities, nature is the producer of nearly 5,000 halogen-containing chemicals. Once dismissed as accidents of nature or isolation artifacts, organohalogen compounds represent an important and ever growing class of natural products, in many cases exhibiting exceptional biological activity. Since the last comprehensive review in 1996 (Vol. 68, this series), there have been discovered an additional 2,500 organochlorine, organobromine, and other organohalogen compounds. These natural organohalogens are biosynthesized by bacteria, fungi, lichen, plants, marine organisms of all types, insects, and higher animals including humans. These compounds are also formed abiogenically, as in volcanoes, forest fires, and other geothermal events.In some instances, natural organohalogens are precisely the same chemicals that man synthesizes for industrial use, and some of the quantities of these natural chemicals far exceed the quantities emitted by man.

Catalytic Carbonylation Reactions

Catalytic Carbonylation Reactions PDF Author: Matthias Beller
Publisher: Springer Science & Business Media
ISBN: 354033002X
Category : Science
Languages : en
Pages : 289

Book Description
Carbonylation reactions are of major importance in both organic and industrial chemistry. Due to the availability, price and reactivity pattern, carbon monoxide is becoming a more and more important building block for fine and bulk chemicals. The major reaction types of carbon monoxide are comprehensively discussed by leading experts from academia and industry. The authors highlight important carbonylation reactions such as hydroformylation, alkoxy-carbonylations, co/olefin-copolymerization, Pauson-Khand reactions and others. They illustrate applications in organic synthesis and give industrial examples. This volume is designed to provide graduate students and researchers with essential information on the use of carbon monoxide in organic synthesis. Therefore, the reader will get a balanced view of this developing and complex subject.

Applied Cross-Coupling Reactions

Applied Cross-Coupling Reactions PDF Author: Yasushi Nishihara
Publisher: Springer Science & Business Media
ISBN: 3642323685
Category : Science
Languages : en
Pages : 247

Book Description
“Applied Cross-Coupling Reactions” provides students and teachers of advanced organic chemistry with an overview of the history, mechanisms and applications of cross-coupling reactions. Since the discovery of the transition-metal-catalyzed cross-coupling reactions in 1972, numerous synthetic uses and industrial applications have been developed. The mechanistic studies of the cross-coupling reactions have disclosed that three fundamental reactions: oxidative addition, transmetalation, and reductive elimination, are involved in a catalytic cycle. Cross-coupling reactions have allowed us to produce a variety of compounds for industrial purposes, such as natural products, pharmaceuticals, liquid crystals and conjugate polymers for use in electronic devices. Indeed, the Nobel Prize for Chemistry in 2010 was awarded for work on cross-coupling reactions. In this book, the recent trends in cross-coupling reactions are also introduced from the point of view of synthesis design and catalytic activities of transition-metal catalysts.