Author: British Library. Document Supply CentrePublisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 788
Book Description
British Reports, Translations and Theses
Author: British Library. Document Supply CentrePublisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 788
Book Description
Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards
Author: Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 762
Book Description
Theses on any subject submitted by the academic libraries in the UK and Ireland.
Quarterly Journal of the Chemical Society of London
Author: Chemical Society (Great Britain)Publisher:
ISBN:
Category : Chemistry
Languages : en
Pages : 1132
Book Description
Journal of the Chemical Society
Author: Chemistry of Waste Minimization
Author: J.H. ClarkPublisher: Springer Science & Business Media
ISBN: 9401106231
Category : Technology & Engineering
Languages : en
Pages : 573
Book Description
Political pressure has translated into legislation requiring industry to reduce waste. There is an unprecedented opportunity for chemists to develop and apply new methods that result in waste reduction, and this book describes examples of new chemical methods used to reduce waste at source and to treat toxic waste.
Chemistry and Application of H-Phosphonates
Author: Kolio D. TroevPublisher: Elsevier
ISBN: 008047649X
Category : Science
Languages : en
Pages : 308
Book Description
Chemistry and Application of H-Phosphonates is an excellent source for those planning the synthesis of new phosphorus-containing compounds and in particular derivatives containing a phosphonate, phosphoramide or phosphonic acid diester group. The rich chemistry, low cost and easy availability of diesters of H-phosphonic acid makes them an excellent choice as synthone in a number of practically important reactions. Phosphonic acid esters are intermediates in the synthesis of important classes of compounds such as alpha-aminophosphonic acids, bisphosphonates, epoxyalkylphosphonates, alpha-hydroxyalkylphosphonates, phosphoramides, poly(alkylene H-phosphonate)s, poly(alkylene phosphate)s, nucleoside H-phosphonates. The synthesis of each of these compound classes is reviewed in detail. Alpha-Aminophosphonic acids are an important class of biologically active compounds, which have received an increasing amount of attention because they are considered to be structural analogues of the corresponding Alpha-amino acids. The utilities of alpha-aminophosphonates as peptide mimics, haptens of catalytic antibodies, enzyme inhibitors, inhibitors of cancers, tumours, viruses, antibiotics and pharmacologic agents are well documented. Alpha-Hydroxyalkanephosphonates are compounds of significant biological and medicinal applications. Dialkyl epoxyalkylphosphonates are of interest because of their use as intermediates in the synthesis of bioactive substances, and as modifiers of natural and synthetic polymers. Bisphosphonates are drugs that have been widely used in different bone diseases, and have recently been used successfully against many parasites. Poly(alkylene H-phosphonate)s and poly(alkylene phosphate)s are promising, biodegradable, water soluble, new polymer-carriers of drugs. Nucleoside H-phosphonates seem to be the most attractive candidates as starting materials in the chemical synthesis of DNA and RNA fragments. The 5'-hydrogen phosphonate-3'-azido-2',3'-dideoxythimidine is one of the most significant anti-HIV prodrug, which is currently in clinical trials. Chapters review the synthesis; physical and spectral properties (1H, 13C, 31P and 17O NMR data); characteristic reactions; important classes of compounds based on these esters of H-phosphonic acid; their application as physiologically active substances, flame retardants, catalysts, heat and light stabilizers, lubricants, scale inhibitors, polymer-carriers of drugs; preparation of H-phosphonate diesters and general procedures for conducting the most important reactions.* provides ideas for the synthesis of phosphonates, phosphoramides and diesters of phosphonic acid (new phosphorus-containing compounds)* reviews structure, spectra and biological activity of H-phosphonates and their derivatives* examines new areas of application of phosphorus-containing compounds
Dissertation Abstracts International
Author: Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 692
Book Description
Applications of Transition Metal Catalysis in Drug Discovery and Development
Author: Matthew L. CrawleyPublisher: John Wiley & Sons
ISBN: 1118309839
Category : Science
Languages : en
Pages : 386
Book Description
This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development – it is a guide, a historical prospective, a practical compendium, and a source of future direction for the field.
Zinc Catalysis
Author: Stephan EnthalerPublisher: John Wiley & Sons
ISBN: 3527335986
Category : Technology & Engineering
Languages : en
Pages : 326
Book Description
Filling the gap in the market for comprehensive coverage of this hot topic, this timely book covers a wide range of organic transformations, e. g. reductions of unsaturated compounds, oxidation reactions, Friedel-Crafts reactions, hydroamination reactions, depolymerizations, transformations of carbon dioxide, oxidative coupling reactions, as well as C-C, C-N, and C-O bond formation reactions. A chapter on the application of zinc catalysts in total synthesis is also included. With its aim of stimulating further research and discussion in the field, this is a valuable reference for professionals in academia and industry wishing to learn about the latest developments.
Author: