Synaptic Modifications in Hippocampal CA3 Pyramidal Cells in an Alzheimer's Mouse Model PDF Download

Author: Pei Zhang
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Languages : en
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Book Description
Memory encoding is thought to proceed from durable changes in the activity of synaptic circuits, leading to the storage of patterns of electrical events in a sparsely distributed ensemble of neurons. Located at the entry level of hippocampal circuitry, the CA3 region is thought to be important for episodic memory encoding, especially at the initial stage of acquisition, by presumably developing an instant representation of a context. CA3 pyramidal cells receive a variety of inputs, among which the mossy fiber (Mf) inputs draw special attention for their peculiar structure and unique synapti...