Author: Andrew David GazardPublisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Studies in the Synthesis of Some Indole Alkaloids
Author: Andrew David GazardIndole Alkaloids
Author: RahmanPublisher: CRC Press
ISBN: 9789057022685
Category : Science
Languages : en
Pages : 354
Book Description
Indole alkaloids constitute an important class of natural products which include a large number of pharmacologically important substances such as the anti-tumour alkaloids, vinblastine and vincristine, the blood pressure lowering substance reserpine, the hallucinatory lysergic acid and its derivatives, and the cardio-arrhythmic alkaloid, ajmalicine. This important field has attracted the leading synthetic organic chemists of the present century to develop synthetic approaches to the challenging structural architecture encountered in many indole alkaloids. The book describes the syntheses of various types of indole alkaloids.
Studies in the Synthesis of the Indole Alkaloids
Author: Arthur Eugene ObersterPublisher:
ISBN:
Category :
Languages : en
Pages : 204
Book Description
Indole Alkaloids
Author: Maliha UroosPublisher: Elsevier
ISBN: 0323972489
Category : Science
Languages : en
Pages : 236
Book Description
Indole Alkaloids: Spirooxindole details the multistep synthesis of natural products using schematic diagrams, providing a quick-and-easy way to review and understand new and novel synthetic strategies to construct structural frameworks of natural products. As a volume in the Visual Guides to Natural Product Synthesis series, this book presents the schematic total syntheses of natural products containing a “spirooxindole” core structure. It covers spirooxindole molecules through visual diagrams, highlighting key steps involved in total, formal and semi-syntheses. Sections cover Brevianamide A and B, Citrinadin A and B, Coerulescine and Horsfiline, Elacomine and Isoelacomine, Gelsemine, Paraherquamide A and B, Rynchophylline, Isorynchophylline, and more. Visual layouts provide quick-and- easy access to developed synthetic routes towards the targeted spirooxindoles. Outlines synthetic strategies for natural products bearing a spirooxindole core structure Includes schematic diagrams of multistep synthetic routes, highlighting key steps along the way Describes all routes for the formal synthesis, semi-synthesis and total synthesis of spirooxindole alkaloids
Studies Directed Towards the Synthesis of the Indole Alkaloids
Author: Nancy Lucretia SearPublisher:
ISBN:
Category : Indole alkaloids
Languages : en
Pages : 218
Book Description
Studies in the Isolation, Degradation, and Synthesis of Certain Indole Alkaloids
Author: Charles William TaylorPublisher:
ISBN:
Category : Indole
Languages : en
Pages : 224
Book Description
Studies on the Synthesis and Biosynthesis of Indole Alkaloids
Author: Norman G. LewisPublisher:
ISBN:
Category : Indole alkaloids
Languages : en
Pages : 426
Book Description
Studies on the Synthesis and Biosynthesis of Indole Alkaloids
Author: George Bohn FullerPublisher:
ISBN:
Category : Indole alkaloids
Languages : en
Pages : 294
Book Description
Total Synthesis of Indole Alkaloids
Author: Junpei MatsuokaPublisher: Springer Nature
ISBN: 9811586527
Category : Science
Languages : en
Pages : 91
Book Description
This book explores efficient syntheses of indole alkaloids based on gold-catalyzed cascade cyclizations, presenting two strategies for total synthesis of these natural products based on gold-catalyzed reactions of conjugated diyne or ynamide. The book first describes the total and formal synthesis of dictyodendrins A–F based on direct construction of the pyrrolo[2,3-c]carbazole core using the gold-catalyzed annulation of azido-diynes and protected pyrrole. This synthetic strategy features late-stage functionalization of the pyrrolo[2,3-c]carbazole scaffold at several positions and allows diverse access to dictyodendrins and their derivatives. Secondly, the book discusses the formal synthesis of vindorosine based on the pyrrolo[2,3-d]carbazole construction using the gold-catalyzed cascade cyclization of ynamide. Importantly, the reaction using a chiral gold complex provides the optically active pyrrolo[2,3-d]carbazole. This strategy facilitates the rapid construction of the pyrrolocarbazole core structure of aspidosperma and related alkaloids, including vindorosine. These methodologies can accelerate the medicinal application of pyrrolocarbazole-type alkaloids and related compounds.
Studies Related to Synthesis and Biosynthesis of Indole Alkaloids
Author: Verner Robert NelsonPublisher:
ISBN:
Category : Indole
Languages : en
Pages : 274
Book Description