Sterilization and Disinfection by Plasma PDF Download

Author: Akikazu Sakud
Publisher: Nova Biomedical Books
ISBN: 9781616687823
Category : Disinfection and disinfectants
Languages : en
Pages : 0

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Book Description
With the increased importance of hospital administration and continuous emergence of new infectious pathogens, particular attention should be paid to avoid iatrogenic diseases by minimising the contamination of medical instruments with infectious pathogens and toxins. It is well known that one of the most effective ways to prevent hospital-acquired infection is to implement a sterilisation and disinfection system that includes physical and chemical inactivation methods. This book presents information on the current status and future perspectives of a state-of-art physical technique, gas plasma sterilisation.

Author: Hideharu Shintani
Publisher: Caister Academic Press Limited
ISBN: 9781910190258
Category : Medical
Languages : en
Pages : 0

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Book Description
Gas plasma is the fourth state of matter, alongside solid, liquid, and gas. There are many naturally-occurring events and man-made products related to gas plasma, including aurora, thunderstorms, high-intensity discharge headlamp bulbs, oxonizers, semiconductors, and solar battery panels. A gas plasma is generated by removing electrons from a gas, e.g. nitrogen gas, to produce a highly-excited mixture of charged nuclei and free electrons. It has enormous potential as a broad spectrum antimicrobial sterilization procedure with applications in medical, industrial, and agricultural settings (e.g. decontamination of medical instruments). A major advantage is the shallow penetration of gas plasmas: approximately 10-20 nanometers from the surface, thereby minimizing damage to the material being sterilized. An important obstacle to overcome is the 'understanding-gap' between the engineering researchers who are developing the gas plasma sterilization technology and the microbiologists who aim to fine tune it for their needs. This timely book bridges that gap, permitting engineers and microbiologists to develop more coherent multidisciplinary strategies. The book opens with introductory chapters that explain the background and principles of gas plasma sterilization and outline the possible mechanisms of action. The requirements for achieving the 'gold-standard' sterilization level, i.e. a sterility assurance level (SAL) of 10-6, are also covered. The book also covers the applications of this technology, ranging from the inactivation of spores and endotoxins to inactivation of viruses and seed-borne plant pathogens. The final section of the book tackles sterilization validation (from several ISO documents), common data-interpretation errors, and speculation about future trends. [Subject: Microbiology, Engineering]

Author: Gerald McDonnell
Publisher: Lippincott Williams & Wilkins
ISBN: 1496381505
Category : Medical
Languages : en
Pages : 2941

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Book Description
With more international contributors than ever before, Block’s Disinfection, Sterilization, and Preservation, 6th Edition, is the first new edition in nearly 20 years of the definitive technical manual for anyone involved in physical and chemical disinfection and sterilization methods. The book focuses on disease prevention—rather than eradication—and has been thoroughly updated with new information based on recent advances in the field and understanding of the risks, the technologies available, and the regulatory environments.

Author: Zdenko Machala
Publisher: Springer Science & Business Media
ISBN: 9400728522
Category : Science
Languages : en
Pages : 479

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Book Description
Non-thermal (cold) plasmas at atmospheric pressure have recently found many breakthrough applications in biology, medicine, and food security. Plasmas can efficiently kill bacteria, yeasts, moulds, spores, biofilms and other hazardous microorganisms, including potential bio-terrorism agents. They can be employed for bio-decontamination and sterilization of surfaces, medical instruments, water, air, food, even of living tissues without causing their damage. Direct or indirect plasma interaction with living cells of microorganisms or even humans enables novel bio-medical applications, e.g. treatment of skin diseases and ulcers. Plasma-enhanced blood coagulation coupled with its antiseptic properties proved success in wound healing and opens new possibilities in surgery, emergency medicine and military applications. Plasma treatment allows cell manipulations, their removal and targeted transfer into the injured area, which can accelerate wound healing. Plasma induced apoptosis (programmed cell death) of tumor cells brings forth a great potential for cancer treatment. Besides, plasma enables painless treatment of dental caries, root canal disinfection, and other dentistry applications. This book is a selection of reviewed manuscripts issuing from the NATO Advanced Research Workshop Plasma for bio-decontamination, medicine and food security held in Jasná, Slovakia, on 15-18 March 2011. It provides a comprehensive overview of the current knowledge and research activities focused at the plasma applications in areas such as bio-decontamination, water chemistry, effects on cells; biofilm inactivation, UV sterilization, and medicine, especially tissue treatment and wound healing, as well as dentistry and food security.

Author: Selçuk Güçeri
Publisher: Springer Science & Business Media
ISBN: 1402084390
Category : Science
Languages : en
Pages : 306

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Book Description
Plasma decontamination is a rapidly expanding area of modern science and engineering. An increasing number of engineers are using plasma methods for decontamination of chemical and biological agents. Plasma decontamination is effectively applied today to clean and sterilize different surfaces, high volume air and water streams, industrial exhausts, and even living tissue of animals and humans. This book provides a fundamental introduction to virtually all aspects of modern plasma decontamination, as well as the most recent technological achievements in the area. The book is segmented into four specific sections of modern plasma decontamination: (1) plasma bio-decontamination, including disinfection and sterilization of surfaces, water and air streams; (2) plasma decontamination of chemical agents, including cleaning of air, water, and industrial exhaust gases from different pollutants and especially volatile organic compounds VOC; (3) plasma treatment of living tissue, including different subjects of plasma medicine from skin sterilization to tissue engineering; (4) major electric discharges applied for the plasma-assisted decontamination of chemical and biological agents.

Author: Gerald E. McDonnell
Publisher: John Wiley & Sons
ISBN: 1555819680
Category : Medical
Languages : en
Pages : 431

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Book Description
Antisepsis, Disinfection, and Sterilization: Types, Action, and Resistance, by Gerald E. McDonnell, is a detailed and accessible presentation of the current methods of microbial control. Each major category, such as physical disinfection methods, is given a chapter, in which theory, spectrum of activity, advantages, disadvantages, and modes of action of the methods are thoroughly and clearly presented. Sufficient background on the life cycles and general anatomy of microorganisms is provided so that the reader who is new to microbiology will better appreciate how physical and chemical biocides work their magic on microbes. Other topics in the book include: Evaluating the efficacy of chemical antiseptics and disinfectants, and of physical methods of microbial control and sterilization. Understanding how to choose the proper biocidal product and process for specific applications. Classic physical and chemical disinfection methods, such as heat, cold, non-ionizing radiation, acids, oxidizing agents, and metals. Newer chemical disinfectants, including, isothiazolones, micro-and nano-particles, and bacteriophages as control agents. Antisepsis of skin and wounds and the biocides that can be used as antiseptics. Classic methods of physical sterilization, such as, moist heat and dry heat sterilization, ionizing radiation, and filtration, along with newer methods, including, the use of plasma or pulsed light. Chemical sterilization methods that use ethylene oxide, formaldehyde, or a variety of other oxidizing agents. A detailed look at the modes of action of biocides in controlling microbial growth and disrupting microbial physiology. Mechanisms that microorganisms use to resist the effects of biocides. The second edition of Antisepsis, Disinfection, and Sterilization: Types, Action, and Resistance is well suited as a textbook and is outstanding as a reference book for facilities managers and application engineers in manufacturing plants, hospitals, and food production facilities. It is also essential for public health officials, healthcare professionals, and infection control practitioners.

Author: Ebbing Lautenbach
Publisher: Cambridge University Press
ISBN: 1107153166
Category : Medical
Languages : en
Pages : 455

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Book Description
A clear, hands-on outline of best practices for infection prevention that directly improve patient outcomes across the healthcare continuum.

Author: Seymour Stanton Block
Publisher: Lippincott Williams & Wilkins
ISBN: 9780683307405
Category : Medical
Languages : en
Pages : 1448

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Book Description
This new edition is a comprehensive, practical reference on contemporary methods of disinfection, sterlization, and preservation and their medical, surgical, and public health applications. New topics covered include recently identified pathogens, microbial biofilms, use of antibiotics as antiseptics, synergism between chemical microbicides, pulsed-light sterilization of pharmaceuticals, and new methods for medical waste management. (Midwest).

Author: Spencer P Kuo
Publisher: World Scientific
ISBN: 9813279869
Category : Science
Languages : en
Pages : 210

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Book Description
Cold atmospheric plasma (CAP) generators have been actively developed as a new device for medical treatment. The applications of plasma treatment include 1) disinfection, sterilization, and decontamination, which inactivates or kills bacteria, fungi, viruses and spores; 2) bleeding control, which coagulates blood swiftly; 3) wound healing, which shortens the healing period and benefits the regeneration of the epithelization of tissue to avoid scar formation; etc.Biomedical applications of CAPs are explored via either in-vitro assays, or in-vivo tests using pigs as animal models; tests include sterilization of oral pathogens and biofilm, decontamination of biological warfare agent, blood clotting and rapid control of active life-threatening hemorrhage, and post-operative observation of wound healing after plasma treatment. The conventional approaches in each application are first introduced, then the advantages of plasma treatments are discussed and demonstrated by the test results. The mechanisms of CAPs' biocidal effect, blood clotting effect, and wound healing effect are presented and discussed.

Author: Adam P. Fraise
Publisher: John Wiley & Sons
ISBN: 0470755067
Category : Medical
Languages : en
Pages : 691

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Book Description
Highly respected, established text – a definitive reference in its field – covering in detail many methods of the elimination or prevention of microbial growth "highly recommended to hospital and research personnel, especially to clinical microbiologists, infectioncontrol and environmental-safety specialists, pharmacists, and dieticians." New England Journal of Medicine WHY BUY THIS BOOK? Completely revised and updated to reflect the rapid pace of change in this area Updated material on new and emerging technologies, focusing on special problems in hospitals, dentistry and pharmaceutical practice Gives practical advise on problems of disinfection and antiseptics in hospitals Discusses increasing problems of natural and acquired resistance to antibiotics New contributors give a fresh approach to the subject and ensure international coverage Systematic review of sterilization methods, with uses and advantages outlined for each Evaluation of disinfectants and their mechanisms of action