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Author: Anastasios A. Tsiatis Publisher: CRC Press ISBN: 1498769780 Category : Mathematics Languages : en Pages : 602
Book Description
Dynamic Treatment Regimes: Statistical Methods for Precision Medicine provides a comprehensive introduction to statistical methodology for the evaluation and discovery of dynamic treatment regimes from data. Researchers and graduate students in statistics, data science, and related quantitative disciplines with a background in probability and statistical inference and popular statistical modeling techniques will be prepared for further study of this rapidly evolving field. A dynamic treatment regime is a set of sequential decision rules, each corresponding to a key decision point in a disease or disorder process, where each rule takes as input patient information and returns the treatment option he or she should receive. Thus, a treatment regime formalizes how a clinician synthesizes patient information and selects treatments in practice. Treatment regimes are of obvious relevance to precision medicine, which involves tailoring treatment selection to patient characteristics in an evidence-based way. Of critical importance to precision medicine is estimation of an optimal treatment regime, one that, if used to select treatments for the patient population, would lead to the most beneficial outcome on average. Key methods for estimation of an optimal treatment regime from data are motivated and described in detail. A dedicated companion website presents full accounts of application of the methods using a comprehensive R package developed by the authors. The authors’ website www.dtr-book.com includes updates, corrections, new papers, and links to useful websites.
Author: Anastasios A. Tsiatis Publisher: CRC Press ISBN: 1498769780 Category : Mathematics Languages : en Pages : 602
Book Description
Dynamic Treatment Regimes: Statistical Methods for Precision Medicine provides a comprehensive introduction to statistical methodology for the evaluation and discovery of dynamic treatment regimes from data. Researchers and graduate students in statistics, data science, and related quantitative disciplines with a background in probability and statistical inference and popular statistical modeling techniques will be prepared for further study of this rapidly evolving field. A dynamic treatment regime is a set of sequential decision rules, each corresponding to a key decision point in a disease or disorder process, where each rule takes as input patient information and returns the treatment option he or she should receive. Thus, a treatment regime formalizes how a clinician synthesizes patient information and selects treatments in practice. Treatment regimes are of obvious relevance to precision medicine, which involves tailoring treatment selection to patient characteristics in an evidence-based way. Of critical importance to precision medicine is estimation of an optimal treatment regime, one that, if used to select treatments for the patient population, would lead to the most beneficial outcome on average. Key methods for estimation of an optimal treatment regime from data are motivated and described in detail. A dedicated companion website presents full accounts of application of the methods using a comprehensive R package developed by the authors. The authors’ website www.dtr-book.com includes updates, corrections, new papers, and links to useful websites.
Author: Kazuichi Hayakawa Publisher: Springer ISBN: 9789811067747 Category : Medical Languages : en Pages : 0
Book Description
This book reviews Polycyclic Aromatic Hydrocarbons (PAHs) and Nitropolycyclic Aromatic Hydrocarbons (NPAHs) contamination in the context of environmental pollution in Asia. It is comprised of the following sections: 1. Fundamental Chemistry and General Characteristics; 2. Analytical Methods; 3. Emission Source and Atmospheric Behavior; 4. Atmospheric Polycyclic Aromatic Hydrocarbons and PM2.5; 5. Polycyclic Aromatic Hydrocarbons in Marine Environments; 6. Metabolic Activation/Toxicities; and 7. Environmental Standards and Guidelines. This volume concentrates on the Far East due to the massive consumption of coal and petroleum in China, which has led to considerable levels of air pollution. High concentration of atmospheric PM2.5 in Beijing have been reported since January 2013 and exposure to such high concentrations may cause respiratory, cardiac and lung diseases. Gathering contributions from international experts, this volume provides a valuable reference guide for global researchers and students interested in learning from the East Asian experience.
Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Publisher: IARC Monographs on the Evaluat ISBN: 9789283201472 Category : Medical Languages : en Pages : 0
Book Description
"This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risk to Humans, which met in Lyon, 8-15 October 2013."
Author: David L. DeMets Publisher: Springer Science & Business Media ISBN: 0387301070 Category : Medical Languages : en Pages : 389
Book Description
From the authors of "Fundamentals of Clinical Trials" which has sold over 15,000 copies world wide since its publication in 1998. No competition yet as the text does not focus on how to do clinical trials but on very specific situations that can be encountered during the process.
Author: Federal Council for Science and Technology (U.S.). Committee on Scientific and Technical Information Publisher: ISBN: Category : Subject headings Languages : en Pages : 74
Author: J. Kielhorn Publisher: Environmental Health Criteria ISBN: Category : Medical Languages : en Pages : 526
Book Description
The Environmental Health Criteria Programme (EHC) evaluates information on the relationship between exposure to environmental pollutants and human health, in order to establish guidelines for setting exposure limits. This publication focuses on the risks posed by exposures to selected nitro-and nitro-oxy-polycyclic aromatic hydrocarbons (nitroPAHs). These are derivaties of polycyclic aromatic hydrocarbons (PAHS) which contain two or more fused aromatic rings made of carbon and hydrogen atoms.
Author: Muharrem Ince Publisher: ISBN: 9781839680311 Category : Languages : en Pages : 98
Book Description
This book covers hydrocarbon pollution, measurement techniques for hydrocarbons, risk assessment, and environmental impact. This comprehensive book takes a broad view of the subject and integrates a wide variety of approaches. This book attempts to address the needs of graduate and postgraduate students and other professionals or readers interested in food, soil, water, and air pollution. The aim of this book is to explain and clarify important studies, and compare and develop the new and groundbreaking measurement techniques. Written by leading experts in their respective areas, the book is highly recommended to professionals interested in environmental and human health because it provides specific and comprehensive examples.
Author: Josette Murphy Publisher: ISBN: Category : Business & Economics Languages : en Pages : 100
Book Description
The paper provides guidelines for managers and technical staff in extension agencies who plan, organize, implement and utilize monitoring activities and, when necessary, subsequent evaluations. It defines the information needs of extension managers, discusses administrative and logistic requirements, and reviews techniques for data collection, analysis, presentation and dissemination which experience has shown to be realistic and timely for extension agencies. The Training and Visit approach to agricultural extension services facilitates the organization and utilization of a monitoring system because of its detailed work programs, intensive training and supervision of field agents, and systematic feedback from the farmers to management. The paper focuses on extension agencies using the T & V approach but is of general application for any extension method.
Author: Asian Development Bank Publisher: Asian Development Bank ISBN: 9292625837 Category : Health & Fitness Languages : en Pages : 102
Book Description
The economic and social impacts of the coronavirus disease (COVID-19) have been dramatic, and transport has played a central role in its spread. The transport sector has also enabled essential workers to get to work during the pandemic and will support the needs of the population throughout the different stages of recovery. This guidance note presents (i) the impacts of the pandemic on social and travel behaviors in Asia and the Pacific, and how the transport sector is responding; and (ii) guiding principles and good practices in transport operations to support economic recovery.
Author: Olga Bernad-Cavero Publisher: BoD – Books on Demand ISBN: 1789233801 Category : Education Languages : en Pages : 318
Book Description
The societies of the twenty-first century are subject to social, cultural, political, and economic changes. In this context, the school is asked to educate the future citizens in the present. To respond to this kaleidoscopic reality, the school is immersed in a pedagogical revolution. In this book, the reader will find a selection of avant-garde research works from different disciplines and contexts, which have their epicenter in the school and in the faculties of education. New issues in pedagogy and education, and new roles of teachers and students, are discussed in a global and diverse context. And new methodological and formative proposals are also proposed to build the ideal school and the ideal teacher, from the initial and continuous teacher training.
Author: Anastasios A. Tsiatis
Author: Anastasios A. Tsiatis
Author: Kazuichi Hayakawa
Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Author: David L. DeMets
Author: Federal Council for Science and Technology (U.S.). Committee on Scientific and Technical Information
Author: J. Kielhorn
Author: Muharrem Ince
Author: Josette Murphy
Author: Asian Development Bank
Author: Olga Bernad-Cavero