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Solvent Neurotoxicity

Solvent Neurotoxicity PDF Author: Peter Arlien-Soborg
Publisher: CRC Press
ISBN: 9780849362347
Category : Medical
Languages : en
Pages : 404

Book Description
Solvent Neurotoxicity presents a comprehensive summary of the latest information available regarding acute and chronic neurotoxicity of a number of solvents. Ten solvents (Chloromethane; Dichloromethane; N-Hexane; Methyl Ethyl Ketone; Methyln N-Butyl Ketone; Styrene; Toluene; 1,1,1-Trichloroethane, Trichloroethylene, and Xylene) and two mixtures of solvents (White Spirit, Mixed solvent exposure) have been selected based on their widespread use, as well as the mounting evidence from research concerning the neurotoxicity of these particular solvents. Evidence is presented from animal and human experiments, clinical observations, and epidemiological studies. The various methods used to establish a neurological diagnosis are described as well, and the advantages and disadvantages of these methods are discussed. Researchers involved in solvent neurotoxicological studies, occupational hygiene specialists, epidemiologists, and trade unions and industries whose members and employees work with organic solvents will find this book to be essential in determining methods for preventing chronic toxic neuropathy, encephalopathy, and other solvent-related disorders.

Solvent Neurotoxicity

Solvent Neurotoxicity PDF Author: Peter Arlien-Soborg
Publisher: CRC Press
ISBN: 9780849362347
Category : Medical
Languages : en
Pages : 404

Book Description
Solvent Neurotoxicity presents a comprehensive summary of the latest information available regarding acute and chronic neurotoxicity of a number of solvents. Ten solvents (Chloromethane; Dichloromethane; N-Hexane; Methyl Ethyl Ketone; Methyln N-Butyl Ketone; Styrene; Toluene; 1,1,1-Trichloroethane, Trichloroethylene, and Xylene) and two mixtures of solvents (White Spirit, Mixed solvent exposure) have been selected based on their widespread use, as well as the mounting evidence from research concerning the neurotoxicity of these particular solvents. Evidence is presented from animal and human experiments, clinical observations, and epidemiological studies. The various methods used to establish a neurological diagnosis are described as well, and the advantages and disadvantages of these methods are discussed. Researchers involved in solvent neurotoxicological studies, occupational hygiene specialists, epidemiologists, and trade unions and industries whose members and employees work with organic solvents will find this book to be essential in determining methods for preventing chronic toxic neuropathy, encephalopathy, and other solvent-related disorders.

Behavioral Measures of Neurotoxicity

Behavioral Measures of Neurotoxicity PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309040477
Category : Science
Languages : en
Pages : 449

Book Description
Exposure to toxic chemicalsâ€"in the workplace and at homeâ€"is increasing every day. Human behavior can be affected by such exposure and can give important clues that a person or population is in danger. If we can understand the mechanisms of these changes, we can develop better ways of testing for toxic chemical exposure and, most important, better prevention programs. This volume explores the emerging field of neurobehavioral toxicology and the potential of behavior studies as a noninvasive and economical means for risk assessment and monitoring. Pioneers in this field explore its promise for detecting environmental toxins, protecting us from exposure, and treating those who are exposed.

Organic Solvent Neurotoxicity

Organic Solvent Neurotoxicity PDF Author:
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 44

Book Description


Environmental Neurotoxicology

Environmental Neurotoxicology PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309045312
Category : Science
Languages : en
Pages : 167

Book Description
Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

Neurotoxicity Testing of Organic Solvents in Laboratory Animals

Neurotoxicity Testing of Organic Solvents in Laboratory Animals PDF Author:
Publisher: Nordic Council of Ministers
ISBN: 9789291208463
Category : Laboratory animals
Languages : en
Pages : 102

Book Description


The Neurotoxicity of Industrial Solvents

The Neurotoxicity of Industrial Solvents PDF Author: Edward L. Baker
Publisher:
ISBN:
Category : Neurotoxic agents
Languages : en
Pages : 12

Book Description


Relationships of Blood and Brain Halocarbon Solvent Concentrations to Neurobehavioral Toxicity

Relationships of Blood and Brain Halocarbon Solvent Concentrations to Neurobehavioral Toxicity PDF Author: David Alan Warren
Publisher:
ISBN:
Category :
Languages : en
Pages : 264

Book Description
Time-courses of blood and brain concentrations and neurobehavioral toxicity were determined for two halocarbon solvents in two rodent species. Based on these data, quantitative relationships, or the lack thereof, have been reported between the degree of neurobehavioral toxicity and internal measures of dose. In the case of orally- administered perchloroethylene (PCE), relationships between blood and brain concentrations and operant performance were not discernable, due in part to an acute adaptation of rats to PCE's response suppressing effect. For inhaled 1,1,1- trichloroethane (TRI), blood and brain concentrations were strongly correlated with the rate of operant responding in rats.

Occupational Neurology

Occupational Neurology PDF Author:
Publisher: Elsevier
ISBN: 044462628X
Category : Medical
Languages : en
Pages : 546

Book Description
Occupational Neurology a volume in the Handbook of Clinical Neurology Series, provides a comprehensive overview of the science, clinical diagnosis, and treatment for neurotoxin related neurological and psychiatric disorders. This timely collection provides not only a complete scientific reference on the chemical origin of this class of neurological and psychiatric disorders, but also a practical guide to diagnosis and treatment challenges and best practices. Handbook of Clinical Neurology Series The first volume of the Handbook of Clinical Neurology under the editorship of George Bruyn and Pierre Vinken was published in 1968. In 1982, the series was brought to an interim conclusion with the publication of the cumulative index volume (Volume 44). By that stage, the Handbook had come to represent one of the largest scientific works ever published. It enjoys a high reputation in specialist media circles throughout the world. After the series was concluded in 1982, it was realized that an update of the material was imperative. Accordingly, a revised series was planned and published over the following years, concluding with the publication of another cumulative index to both series (Volume 76-78) in 2002. Since then, George Bruyn has passed away and Pierre Vinken has retired, but the need for a further new series, incorporating advances in the field, again become necessary. Professors Michael J. Aminoff, François Boller and Dick F. Swaab have with enthusiasm taken on the responsibility of supervising the preparation of a third series, the first volumes of which were published in 2003. Now, more than 130 volumes after the first published, the Handbook of Clinical Neurology series continues to have an unparalleled reputation for providing the latest foundational research, diagnosis, and treatment protocols essential for both basic neuroscience research and clinical neurology. - Provides comprehensive coverage of neurotoxins, especially in the workplace - Details the latest science as the foundation for neurotoxicity diagnosis and treatment - Presents coverage of the diagnosis and treatment essential for clinical neurologists and occupational medicine specialists

Toxicologic Assessment of Jet-Propulsion Fuel 8

Toxicologic Assessment of Jet-Propulsion Fuel 8 PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309168708
Category : Nature
Languages : en
Pages : 229

Book Description
This report provides a critical review of toxicologic, epidemiologic, and other relevant data on jet-propulsion fuel 8, a type of fuel in wide use by the U.S. Department of Defense (DOD), and an evaluation of the scientific basis of DOD's interim permissible exposure level of 350 mg/m3

Clinical Environmental Health and Toxic Exposures

Clinical Environmental Health and Toxic Exposures PDF Author: John Burke Sullivan
Publisher: Lippincott Williams & Wilkins
ISBN: 9780683080278
Category : Medical
Languages : en
Pages : 1348

Book Description
Now in its revised and updated Second Edition, this volume is the most comprehensive and authoritative text in the rapidly evolving field of environmental toxicology. The book provides the objective information that health professionals need to prevent environmental health problems, plan for emergencies, and evaluate toxic exposures in patients.Coverage includes safety, regulatory, and legal issues; clinical toxicology of specific organ systems; emergency medical response to hazardous materials releases; and hazards of specific industries and locations. Nearly half of the book examines all known toxins and environmental health hazards. A Brandon-Hill recommended title.