Author: Charles Audet Publisher: Springer ISBN: 3319689134 Category : Mathematics Languages : en Pages : 307
Book Description
This book is designed as a textbook, suitable for self-learning or for teaching an upper-year university course on derivative-free and blackbox optimization. The book is split into 5 parts and is designed to be modular; any individual part depends only on the material in Part I. Part I of the book discusses what is meant by Derivative-Free and Blackbox Optimization, provides background material, and early basics while Part II focuses on heuristic methods (Genetic Algorithms and Nelder-Mead). Part III presents direct search methods (Generalized Pattern Search and Mesh Adaptive Direct Search) and Part IV focuses on model-based methods (Simplex Gradient and Trust Region). Part V discusses dealing with constraints, using surrogates, and bi-objective optimization. End of chapter exercises are included throughout as well as 15 end of chapter projects and over 40 figures. Benchmarking techniques are also presented in the appendix.
Author: Ralf Pörtner Publisher: Springer Nature ISBN: 3031456696 Category : Science Languages : en Pages : 497
Book Description
This volume “Cell Engineerring 11 - Biopharmaceutical Manufacturing: Progress, Trends and Challenges” is a source of the latest innovative research and technical development in biomanufacturing systems. It is organised into 2 parts: 1) Manufacturing of recombinant therapeutic proteins (e.g. therapeutic antibodies, biosimilars/biogenerics) and 2) Manufacturing aspects of cell and gene therapy. Each with selected chapters on the following topics for both up- and downstream, such as: Advanced process strategies, especially continuous manufacturing, Advanced culture techniques, especially single-use systems, Process transfer, scale-up/scale-down models, Processing advances/Manufacturing productivity/efficiency, Model-assisted process understanding and development/Digital Twins, Process controls and analytics, Quality control, Quality by design, Facility design and full-scale commercial systems, manufacturing technology innovation. The book comprises contributions of experts from academia and industry active in the field of cell culture development for the production of recombinant proteins, cell therapy and gene therapy, with consideration of Digital Twin ́s and facility design. The knowledge and expertise of the authors cover disciplines like cell biology, engineering, biotechnology and biomedical sciences. Inevitably, some omissions will occur in the test, but the authors have sought to avoid duplications by extensive cross-referencing to chapters in other volumes of this series and elsewhere. We hope the volume provides a useful compendium of techniques for scientists in industrial and research laboratories active in this field.
Author: Linas Stripinis Publisher: Springer Nature ISBN: 3031465377 Category : Mathematics Languages : en Pages : 131
Book Description
After providing an in-depth introduction to derivative-free global optimization with various constraints, this book presents new original results from well-known experts on the subject. A primary focus of this book is the well-known class of deterministic DIRECT (DIviding RECTangle)-type algorithms. This book describes a new set of algorithms derived from newly developed partitioning, sampling, and selection approaches in the box- and generally-constrained global optimization, including extensions to multi-objective optimization. DIRECT-type optimization algorithms are discussed in terms of fundamental principles, potential, and boundaries of their applicability. The algorithms are analyzed from various perspectives to offer insight into their main features. This explains how and why they are effective at solving optimization problems. As part of this book, the authors also present several techniques for accelerating the DIRECT-type algorithms through parallelization and implementing efficient data structures by revealing the pros and cons of the design challenges involved. A collection of DIRECT-type algorithms described and analyzed in this book is available in DIRECTGO, a MATLAB toolbox on GitHub. Lastly, the authors demonstrate the performance of the algorithms for solving a wide range of global optimization problems with various constraints ranging from a few to hundreds of variables. Additionally, well-known practical problems from the literature are used to demonstrate the effectiveness of the developed algorithms. It is evident from these numerical results that the newly developed approaches are capable of solving problems with a wide variety of structures and complexity levels. Since implementations of the algorithms are publicly available, this monograph is full of examples showing how to use them and how to choose the most efficient ones, depending on the nature of the problem being solved. Therefore, many specialists, students, researchers, engineers, economists, computer scientists, operations researchers, and others will find this book interesting and helpful.
Author: Slawomir Koziel Publisher: Springer Science & Business Media ISBN: 3642208584 Category : Computers Languages : en Pages : 292
Book Description
Computational optimization is an important paradigm with a wide range of applications. In virtually all branches of engineering and industry, we almost always try to optimize something - whether to minimize the cost and energy consumption, or to maximize profits, outputs, performance and efficiency. In many cases, this search for optimality is challenging, either because of the high computational cost of evaluating objectives and constraints, or because of the nonlinearity, multimodality, discontinuity and uncertainty of the problem functions in the real-world systems. Another complication is that most problems are often NP-hard, that is, the solution time for finding the optimum increases exponentially with the problem size. The development of efficient algorithms and specialized techniques that address these difficulties is of primary importance for contemporary engineering, science and industry. This book consists of 12 self-contained chapters, contributed from worldwide experts who are working in these exciting areas. The book strives to review and discuss the latest developments concerning optimization and modelling with a focus on methods and algorithms for computational optimization. It also covers well-chosen, real-world applications in science, engineering and industry. Main topics include derivative-free optimization, multi-objective evolutionary algorithms, surrogate-based methods, maximum simulated likelihood estimation, support vector machines, and metaheuristic algorithms. Application case studies include aerodynamic shape optimization, microwave engineering, black-box optimization, classification, economics, inventory optimization and structural optimization. This graduate level book can serve as an excellent reference for lecturers, researchers and students in computational science, engineering and industry.
Author: Stefan Radl Publisher: Elsevier ISBN: 0444642366 Category : Technology & Engineering Languages : en Pages : 1766
Book Description
28th European Symposium on Computer Aided Process Engineering, Volume 43 contains the papers presented at the 28th European Society of Computer-Aided Process Engineering (ESCAPE) event held in Graz, Austria June 10-13 , 2018. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students, and consultants for chemical industries. Presents findings and discussions from the 28th European Society of Computer-Aided Process Engineering (ESCAPE) event
Author: Metin Türkay Publisher: Elsevier ISBN: 0323885136 Category : Technology & Engineering Languages : en Pages : 2146
Book Description
The 31st European Symposium on Computer Aided Process Engineering: ESCAPE-31, Volume 50 contains the papers presented at the 31st European Symposium of Computer Aided Process Engineering (ESCAPE) event held in Istanbul, Turkey. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students and consultants in the chemical industries. - Presents findings and discussions from the 31st European Symposium of Computer Aided Process Engineering (ESCAPE) event
Author: Fabio Caraffini Publisher: MDPI ISBN: 3039434543 Category : Technology & Engineering Languages : en Pages : 286
Book Description
The vast majority of real-world problems can be expressed as an optimisation task by formulating an objective function, also known as cost or fitness function. The most logical methods to optimise such a function when (1) an analytical expression is not available, (2) mathematical hypotheses do not hold, and (3) the dimensionality of the problem or stringent real-time requirements make it infeasible to find an exact solution mathematically are from the field of Evolutionary Computation (EC) and Swarm Intelligence (SI). The latter are broad and still growing subjects in Computer Science in the study of metaheuristic approaches, i.e., those approaches which do not make any assumptions about the problem function, inspired from natural phenomena such as, in the first place, the evolution process and the collaborative behaviours of groups of animals and communities, respectively. This book contains recent advances in the EC and SI fields, covering most themes currently receiving a great deal of attention such as benchmarking and tunning of optimisation algorithms, their algorithm design process, and their application to solve challenging real-world problems to face large-scale domains.
Author: Publisher: Elsevier ISBN: 0444634428 Category : Technology & Engineering Languages : en Pages : 835
Book Description
This volume collects together the presentations at the Eighth International Conference on Foundations of Computer-Aided Process Design, FOCAPD-2014, an event that brings together researchers, educators, and practitioners to identify new challenges and opportunities for process and product design. The chemical industry is currently entering a new phase of rapid evolution. The availability of low-cost feedstocks from natural gas is causing renewed investment in basic chemicals in the OECD, while societal pressures for sustainability and energy security continue to be key drivers in technology development and product selection. This dynamic environment creates opportunities to launch new products and processes and to demonstrate new methodologies for innovation, synthesis and design. FOCAPD-2014 fosters constructive interaction among thought leaders from academia, industry, and government and provides a showcase for the latest research in product and process design. - Focuses exclusively on the fundamentals and applications of computer-aided design for the process industries. - Provides a fully archival and indexed record of the FOCAPD14 conference - Aligns the FOCAPD series with the ESCAPE and PSE series
Author: Slawomir Koziel Publisher: Springer ISBN: 3642208592 Category : Technology & Engineering Languages : en Pages : 292
Book Description
Computational optimization is an important paradigm with a wide range of applications. In virtually all branches of engineering and industry, we almost always try to optimize something - whether to minimize the cost and energy consumption, or to maximize profits, outputs, performance and efficiency. In many cases, this search for optimality is challenging, either because of the high computational cost of evaluating objectives and constraints, or because of the nonlinearity, multimodality, discontinuity and uncertainty of the problem functions in the real-world systems. Another complication is that most problems are often NP-hard, that is, the solution time for finding the optimum increases exponentially with the problem size. The development of efficient algorithms and specialized techniques that address these difficulties is of primary importance for contemporary engineering, science and industry. This book consists of 12 self-contained chapters, contributed from worldwide experts who are working in these exciting areas. The book strives to review and discuss the latest developments concerning optimization and modelling with a focus on methods and algorithms for computational optimization. It also covers well-chosen, real-world applications in science, engineering and industry. Main topics include derivative-free optimization, multi-objective evolutionary algorithms, surrogate-based methods, maximum simulated likelihood estimation, support vector machines, and metaheuristic algorithms. Application case studies include aerodynamic shape optimization, microwave engineering, black-box optimization, classification, economics, inventory optimization and structural optimization. This graduate level book can serve as an excellent reference for lecturers, researchers and students in computational science, engineering and industry.
Author: Charles Audet
Author: Ralf Pörtner
Author: Linas Stripinis
Author: Slawomir Koziel
Author: Stefan Radl
Author: Metin Türkay
Author: Fabio Caraffini
Author: Patricia Melin
Author: 
Author: Slawomir Koziel