Basic Principles and Clinical Significance of Oxidative Stress PDF Download

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Basic Principles and Clinical Significance of Oxidative Stress

Basic Principles and Clinical Significance of Oxidative Stress PDF Author: Sivakumar Joghi Thatha Gowder
Publisher: BoD – Books on Demand
ISBN: 9535122002
Category : Science
Languages : en
Pages : 330

Book Description
It is a natural phenomenon for all living organisms in the world to undergo different kinds of stress during their life span. Stress has become a common problem for human beings in this materialistic world. In this period, a publication of any material on stress will be helpful for the human society. The book Basic Principles and Clinical Significance of Oxidative Stress targets all aspects of oxidative stress, including principles, mechanisms, and clinical significance. This book covers four sections: Free Radicals and Oxidative Stress, Natural Compounds as Antioxidants, Antioxidants - Health and Disease, and Oxidative Stress and Therapy. Each of these sections is interwoven with the theoretical aspects and experimental techniques of basic and clinical sciences. This book will be a significant source to scientists, physicians, healthcare professionals, and students who are interested in exploring the effect of stress on human life.

The Significance Test Controversy Revisited

The Significance Test Controversy Revisited PDF Author: Bruno Lecoutre
Publisher: Springer Nature
ISBN: 3662657058
Category : Mathematics
Languages : en
Pages : 206

Book Description
This book explains the misuses and abuses of Null Hypothesis Significance Tests, which are reconsidered in light of Jeffreys’ Bayesian concept of the role of statistical inference, in experimental investigations. Minimizing the technical aspects, the studies focuses mainly on methodological contributions. The first part of the book gives an overview of the major approaches to statistical testing and an enlightening discussion of the philosophies of Fisher, Neyman-Pearson and Jeffrey. The conceptual and methodological implications of current practices of reporting effect sizes and confidence intervals are also examined and challenged. This sheds new light on the "significance testing controversy" and provides an appropriate Bayesian framework for a comprehensive approach to the analysis and interpretation of experimental data. The second part of the book provides concrete Bayesian routine procedures that bypass common misuses of significance testing and are readily applicable in a wide range of real applications. This approach addresses the need for objective reporting of experimental data, that is acceptable to the scientific community. This is emphasized by the name fiducial (from the Latin fiducia = confidence). The fiducial Bayesian procedures provide the reader with a real opportunity to think sensibly about problems of statistical inference. This book prepares students and researchers to critically read statistical analyses reported in the literature and equips them with an appropriate alternative to the use of significance testing.

Economic and Palaeoceanographic Significance of Contourite Deposits

Economic and Palaeoceanographic Significance of Contourite Deposits PDF Author: Geological Society of London
Publisher: Geological Society of London
ISBN: 9781862392267
Category : Science
Languages : en
Pages : 368

Book Description
There has lately been a growth in the number and level of studies of contourite deposits. Most recent studies of contourites have two major lines of interest. One, propelled by the oil industry's continuous move into increasingly deep waters, concerns their economic significance. The other involves the stratigraphic/ palaeoceanographic record of ocean circulation changes imprinted on contourite deposits that can be a key to understanding better the climate-ocean connection. The application of many different theoretical, experimental and empirical resources provided by geophysics, sedimentology, geochemistry, petrology, scale modeling and field geology are used in the 16 papers of this volume, proposing answers to those two main aspects. The papers are subdivided into two major categories (economic interest and stratigraphic/palaeoceanographic significance), with case studies ranging from well-documented drifts to new examples of modern and fossil series, involving a large diversity of geographic and physiographic scenarios worldwide

The Significance Test Controversy

The Significance Test Controversy PDF Author: Ramon E. Henkel
Publisher: Routledge
ISBN: 1351474162
Category : Psychology
Languages : en
Pages : 347

Book Description
Tests of significance have been a key tool in the research kit of behavioral scientists for nearly fifty years, but their widespread and uncritical use has recently led to a rising volume of controversy about their usefulness. This book gathers the central papers in this continuing debate, brings the issues into clear focus, points out practical problems and philosophical pitfalls involved in using the tests, and provides a benchmark from which further analysis can proceed.The papers deal with some of the basic philosophy of science, mathematical and statistical assumptions connected with significance tests and the problems of the interpretation of test results, but the work is essentially non-technical in its emphasis. The collection succeeds in raising a variety of questions about the value of the tests; taken together, the questions present a strong case for vital reform in test use, if not for their total abandonment in research.The book is designed for practicing researchers-those not extensively trained in mathematics and statistics that must nevertheless regularly decide if and how tests of significance are to be used-and for those training for research. While controversy has been centered in sociology and psychology, and the book will be especially useful to researchers and students in those fields, its importance is great across the spectrum of the scientific disciplines in which statistical procedures are essential-notably political science, economics, and the other social sciences, education, and many biological fields as well.Denton E. Morrison is professor, Department of Sociology, Michigan State University.Ramon E. Henkel is associate professor emeritus, Department of Sociology University of Maryland. He teaches as part of the graduate faculty.

The Significance and Regulation of Soil Biodiversity

The Significance and Regulation of Soil Biodiversity PDF Author: Harold P. Collins
Publisher: Springer Science & Business Media
ISBN: 9401104794
Category : Science
Languages : en
Pages : 282

Book Description
The sustainability of both natural and managed ecosystems is strongly influenced by soil biological processes. A major question in soil biology and ecosystem ecology is the extent to which these processes are affected by the function and structure of the soil's biotic community. The Significance and Regulation of Soil Biodiversity presents the discussions of a group of soil biologists and ecosystem ecologists in which they synthesize available information, present innovative methodologies, and develop cross-taxa and cross-habitat collaborations to advance our understanding of soil biodiversity. The volume addresses the extent and regulation of soil biodiversity and describes initial approaches to the linking of soil biodiversity and ecosystem function. Audience: Researchers and students in a wide range of environmental scientific disciplines.

Significance of Food Processing By-products as Contributors to Animal Feeds

Significance of Food Processing By-products as Contributors to Animal Feeds PDF Author: Walter W. Rose
Publisher:
ISBN:
Category : Feeds
Languages : en
Pages : 206

Book Description


Stay Humble, Kick Hard: Finding Success and Significance in Life and Business

Stay Humble, Kick Hard: Finding Success and Significance in Life and Business PDF Author: Benjamin Moriniere
Publisher: Xlibris Corporation
ISBN: 1984554999
Category : Business & Economics
Languages : en
Pages : 165

Book Description
An entrepreneur starts off with dreams of changing the world and quickly run into the hardest times of their life; the mind-numbing, hard work that it takes to start and grow a business. As the stress sets in, every entrepreneur begins to dig deep looking for hope and, most of all, wishing there were instructions or a guidebook that could provide them the answers they need at such a critical moment. This book is a MUST read for goal-oriented people looking for innovative and easy-to-follow processes for business and personal growth; solutions that propelled Benjamin Moriniere to the front of the martial arts and fitness industry. Benjamin Moriniere uses light-hearted stories, practical wisdom and hands-on tools to teach you the secrets to his success. As a former US military officer, award winning HR Manager and life-long martial artist and entrepreneur, his experiences and insight will provide you the tools and mind-set to move to the next level in business and life.

Ecological Significance of the Interactions Among Clay Minerals, Organic Matter and Soil Biota

Ecological Significance of the Interactions Among Clay Minerals, Organic Matter and Soil Biota PDF Author: A. Violante
Publisher: Elsevier
ISBN: 9780444510396
Category : Science
Languages : en
Pages : 464

Book Description
Soil MineralOrganic MatterMicroorganism Interactions and Ecosystem Health presents up-to-date information on the dynamics, transformations and bioavailability of xenobiotics in soil and their impact on ecosystem health, the ecological significance of interactions of metals and metalloids with soil colloids, enzymes and microbial biomass and the role of minerals-organic matter - soil biota interactions in the restoration of perturbed ecosystems. The title comprises two volumes: Volume A: Dynamics, Mobility and Transformation of Pollutants and Nutrients. Volume B: Ecological Significance of the Interactions mong Clay Minerals, Organic Matter and Soil Biota. This title could serve as a basic reference for students, teachers, and researchers by providing in-depth knowledge of the current state of the art in a particular area of soil science.

The Significance of the Temple Incident in the Narratives of the Four Gospels

The Significance of the Temple Incident in the Narratives of the Four Gospels PDF Author: Deolito V. Vistar Jr.
Publisher: Wipf and Stock Publishers
ISBN: 1532654790
Category : Religion
Languages : en
Pages : 161

Book Description
Deolito Vistar brings a new perspective to the interpretation of the temple incident--a key event in Jesus' life--by approaching the subject not from the "historical Jesus" point of view but from that of the authors of the Gospels. Using composition criticism as a method, Vistar sensitively analyzes the four Gospels' accounts of the incident and shows areas of commonalities and crucial areas where the four evangelists have their own distinctive understanding of what Jesus meant by his protest in the temple. This book is a helpful example of the use of composition analysis in the exegesis of Gospel texts. It is also a helpful study of what is now generally taken for granted in Gospel scholarship: that the four evangelists were both historians and theologians.

The methane moment – Cross-boundary significance of methanogens

The methane moment – Cross-boundary significance of methanogens PDF Author: Zhe Lyu
Publisher: Frontiers Media SA
ISBN: 2832547389
Category : Science
Languages : en
Pages : 271

Book Description
Methane is a potent greenhouse gas, a relatively clean burning fossil fuel, but also a renewable biofuel when biologically produced from waste treatment plants. Most (~70%) of the global methane emission comes from methanogenic archaea, namely methanogens that produce methane from simple substrates such as H2/CO2, formate, acetate, methanol, and other methylated compounds. Methanogens are found across all corners of the earth, including but not limited to wetlands, animals and humans, rice fields, landfills, sewage, ocean, termites, and hydrothermal vents. Their extensive adaptations to such a wide range of habitats predict a cross-boundary significance of methanogens in many areas such as the environment, energy, agriculture, biotechnology, and human and animal health. The goal of this Research Topic is to offer a forum that highlights the cross-boundary significance of methanogens by bringing together methanogen research from diverse settings to one place. This cross-boundary significance is currently underappreciated but imperative to collectively understanding and helping to solve some of the biggest and most urgent challenges humanity is facing such as global warming, food and energy insecurity, pollution, and disease. As a more potent and shorter-lived greenhouse gas than CO2, methane has moved to the center stage in our efforts in rapidly combating climate change. Presumably, methanogens and their associated microbes may have been forced into a positive feedback loop to fuel the sharp rise of methane in recent years. On the other hand, methanogens are considered keystone species in the ecosystem, which are vital to the stability of the natural biome therein. However, the roles of methanogens as keystone species across their habitats are underexplored. Moreover, the role of methanogens in human and animal intestinal microbiomes have been reconsidered with evidence for links to disease and impact on nutrition. Last but not the least, methanogens are emerging as a cell factory model for green manufacturing, because of their abilities to convert CO2 to valuable biochemicals. Further efforts in the bioengineering of methanogens have the potential to expand their commercial application from waste treatment to biomanufacturing. We welcome both basic and translational studies relevant to methanogens from any setting. Studies with a focus on methanogens are highly encouraged, and manuscripts having methanogens as a significant component are also welcome. All studies should emphasize and envisage their implications in understanding and/or solving one or more challenges humanity is facing. To encourage submissions from multiple disciplines, this Research Topic is cross-listed with a number of Frontiers journals and sections. Manuscripts in the forms of Original Research, Review (including systematic and mini review), Methods, Hypothesis and Theory, and Perspectives are all welcome. Manuscript summary submissions are highly encouraged but all manuscripts submitted prior to the manuscript submission deadline will receive full consideration. This Research Topic is dedicated to Dr. William Barny Whitman, Emeritus Professor of Microbiology at the University of Georgia, Athens, GA. His 40+ years (and still counting) of productive research in methanogens, roseobacter, and other prokaryotes have contributed to and will continue to inspire new discoveries in the cross-boundary significance of both archaea and bacteria – the unseen majority. COI Statement: S.K.-M.R.R. is co-founder of Arkeon GmbH. M.P. is a consultant for Bausch Health, Ferring Pharmaceuticals Inc., Salvo Health, and Vivante Health Inc.

Significance of antigen and epitope specificity in tuberculosis

Significance of antigen and epitope specificity in tuberculosis PDF Author: Juraj Ivanyi
Publisher: Frontiers Media SA
ISBN: 2889194515
Category : Immunologic diseases. Allergy
Languages : en
Pages : 120

Book Description
Dissection of the specificity of host immune responses following infection with Mycobacterium tuberculosis is essential for designing effective vaccination and diagnostic biomarkers as well as for better understanding of immunopathogenesis of active tuberculosis. The articles in this volume of the Topics in Microbial Immunology review the significance of this area of research from both experimental models and clinical surveys. This includes T cell recognition of MHC permissive epitopes, use of algorithms for genome-based prediction of immunodominant epitopes, evaluation of candidate antigens/epitopes and adjuvants for vaccination and immunodiagnosis. Future research strategies indicate the need for better understanding of the relationship between epitope specificity and the phenotype of responding T cells and search for biomarkers with a capacity to discriminate and predict the change from latent infection to active disease. These research avenues have important potentials for improving the prevention and control of tuberculosis.