Sarcomas of Bone and Soft Tissues in Children and Adolescents PDF Download

Author: Carola A. S. Arndt
Publisher: Springer Nature
ISBN: 303051160X
Category : Bone
Languages : en
Pages : 181

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Book Description
This book is a comprehensive and up-to-date compendium on all aspects of sarcomas of bone and soft tissues in childhood and adolescence. After introductory chapters on the history, epidemiology, and biology of pediatric sarcomas, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. The pathology and biology of this diverse group of tumors are extensively reviewed. Promising new treatment approaches are discussed, and strategies for the development of new agents are appraised. The major common pediatric sarcomas, including osteosarcoma, Ewing sarcoma, rhabdomyosarcoma and non-rhabdomyosarcoma soft tissue sarcoma, are covered in detail. The authors are internationally recognized experts who offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of childhood and adolescent sarcomas and will prove invaluable to specialists, generalists, and trainees alike.

Author: Alberto S. Pappo
Publisher: Springer Science & Business Media
ISBN: 3540294473
Category : Medical
Languages : en
Pages : 247

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Book Description
The field of pediatric bone and soft tissue sarcomas has experienced a gradual but surprising transformation. Fundamental discoveries in the molecular biology of disease, recent breakthroughs in diagnostic imaging, and revolutionary surgical techniques have created unprecedented synergies and a refreshing vision with which to approach the diagnosis and treatment of these pediatric tumors. This book highlights the paths leading to the emergence of such a new vision and presents salient concepts in epidemiology, novel tools in imaging and molecular biology, and principles of drug development as the scaffold to understanding the pathophysiology and treatment of pediatric sarcomas. The book is aimed at providing an up-to-date comprehensive reference text which articulates a multidisciplinary approach for the diagnosis and treatment of each of these often challenging diseases.

Author: Per-Ulf Tunn
Publisher: Springer Science & Business Media
ISBN: 3540779604
Category : Medical
Languages : en
Pages : 372

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Book Description
Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.

Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 194

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Book Description

Author: Martin M. Malawer
Publisher: Springer Science & Business Media
ISBN: 0306484072
Category : Medical
Languages : en
Pages : 618

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Book Description
Steven A. Rosenberg, MD In the past two decades significant progress has quality of life. The use of local radiation therapy has occurred, in the management of patients with mus- had a profound impact on the ability to achieve local loskeletal cancers, that has improved both the survival control. Cooperation between surgeons and radiation and the quality of life of afflicted patients. Changes in therapists often results in the tailoring of surgical p- the management of these patients have mirrored cedures to maximize the combined application of these trends in the entire field of oncology. two effective treatment modalities. Although impact on The most significant change has been improvement overall survival has not been demonstrated due to the in the surgical techniques for the resection of musculo- addition of radiation therapy, important advances in skeletal cancers based on a detailed understanding of improving the quality of life of patients receiving this the anatomic features of each particular tumor site, as combined-modality treatment have been evident. well as an appreciation of the natural biology that affects A third change impacting on the survival of patients the local spread of these tumors. The current volume of with musculoskeletal cancers has been the aggressive Musculoskeletal Cancer Surgery: Treatment of Sarcomas and resection of metastatic deposits.

Author: Juerg Hodler
Publisher: Springer Nature
ISBN: 3030712818
Category : Musculoskeletal system
Languages : en
Pages : 293

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Book Description
This open access book focuses on imaging of the musculoskeletal diseases. Over the last few years, there have been considerable advances in this area, driven by clinical as well as technological developments. The authors are all internationally renowned experts in their field. They are also excellent teachers, and provide didactically outstanding chapters. The book is disease-oriented and covers all relevant imaging modalities, with particular emphasis on magnetic resonance imaging. Important aspects of pediatric imaging are also included. IDKD books are completely re-written every four years. As a result, they offer a comprehensive review of the state of the art in imaging. The book is clearly structured with learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers easily navigate through the text. As an IDKD book, it is particularly valuable for general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic knowledge, and for clinicians interested in imaging as it relates to their specialty.

Author: Marta C. Cohen
Publisher: Cambridge University Press
ISBN: 1316124150
Category : Medical
Languages : en
Pages : 1225

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Book Description
Essentials of Surgical Pediatric Pathology is a clear and practical yet comprehensive guide for trainee pediatric pathologists and non-pediatric pathologists. Each chapter corresponds to one of the main subspecialties, such as dermatopathology, head and neck pathology, and system pathology. Practical guidance is given on handling pediatric specimens and the authors highlight the ways in which common conditions present differently in adults and children. Other chapters cover conditions typical of childhood, including soft tissue tumors and blue round cell tumors. The chapters begin with a brief clinical presentation, followed by a clear macroscopical and histological description of the principal pathologies seen in children. Up-to-date genetic and immunohistochemical information is provided, and the book includes hundreds of high-quality color images. Written and edited by leading international experts in the field, this is an essential resource for trainee pediatric pathologists, as well as general pathologists who may encounter pediatric cases.

Author:
Publisher:
ISBN:
Category : Children
Languages : en
Pages : 336

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Book Description

Author: Mario Campanacci
Publisher: Springer
ISBN: 3662292793
Category : Medical
Languages : en
Pages : 1109

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Book Description
This is an extraordinary book by an extraordinary author. Mario Campa nacci first published three volumes on musculoskeletal neoplasms and other tu mor-like processes in hone and soft parts in Italian in 1981-1985. This book is an update and expansionofthat book, published for the firsttime in English. In this book Dr. Campanacci brings to the readers the vast experience in musculoskel etal oncology of the Rizzoli Orthopaedic Institute in Bologna where he has been head of the Oncology Unit for many years. As such, he has had at his disposal the patient records, radiographs and pathologic material dating back to 1905. In fact, a visitor to the Institute will be shown the radiograph made of the first tumor case on records-that of a giant cell tumor of the distal femur. The wealth of cli nical material that has accumulated at the Rizzoli Institute, with exquisite docu mentation and maintenance is a unique resource and testimonial to not only the author but his predecessors. Under Dr. Campanacci's leadership, the Institute has provided care to the majority of patients with neoplasms throughout Italy. Over the past two decades a treatment team with extraordinary ability in radi ology, imaging, pathology, chemotherapy, as well as orthopedic surgery has been assembled.

Author: National Academies of Sciences Engineering and Medicine
Publisher:
ISBN: 9780309683494
Category :
Languages : en
Pages :

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Book Description
Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.