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Author: Otto Magnus Publisher: Springer Science & Business Media ISBN: 9781402004612 Category : Medical Languages : en Pages : 372
Book Description
Most medical doctors have probably during their studies heard of the `Magnus and De Kleijn reflexes' and may have been aware of their relation to posture. But they know little about their significance and nothing about the man who unravelled the complex physiology of these reflexes and about his work. Rudolf Magnus lived from 1873 until 1927. His work on the physiology of posture was initiated during a short period of work with Sherrington in Liverpool in 1908. Though Magnus was also an authority in the field of pharmacology, it was particularly his neurophysical work on posture which made him known worldwide. It led to his nomination, together with De Kleijn, for the Nobel Prize in 1927. Unfortunately he died before the decision was made. In this illustrated biography Magnus' family background and his student years are described in a lively way. Fragments of the diary of his journey to England in 1898 and the description of his scientific career in Heidelberg will enlighten those interested in the history of how science was conducted during his lifetime. His lectures on Goethe as a scientist are also included. This is followed by Magnus' life as Professor of Pharmacology in Utrecht, and his studies on animal postures and experimental pharmacology. Finally Magnus' legacy is described.
Author: Otto Magnus Publisher: Springer Science & Business Media ISBN: 9781402004612 Category : Medical Languages : en Pages : 372
Book Description
Most medical doctors have probably during their studies heard of the `Magnus and De Kleijn reflexes' and may have been aware of their relation to posture. But they know little about their significance and nothing about the man who unravelled the complex physiology of these reflexes and about his work. Rudolf Magnus lived from 1873 until 1927. His work on the physiology of posture was initiated during a short period of work with Sherrington in Liverpool in 1908. Though Magnus was also an authority in the field of pharmacology, it was particularly his neurophysical work on posture which made him known worldwide. It led to his nomination, together with De Kleijn, for the Nobel Prize in 1927. Unfortunately he died before the decision was made. In this illustrated biography Magnus' family background and his student years are described in a lively way. Fragments of the diary of his journey to England in 1898 and the description of his scientific career in Heidelberg will enlighten those interested in the history of how science was conducted during his lifetime. His lectures on Goethe as a scientist are also included. This is followed by Magnus' life as Professor of Pharmacology in Utrecht, and his studies on animal postures and experimental pharmacology. Finally Magnus' legacy is described.
Author: Tara Abraham Publisher: MIT Press ISBN: 026203509X Category : Biography & Autobiography Languages : en Pages : 321
Book Description
The life and work of a scientist who spent his career crossing disciplinary boundaries—from experimental neurology to psychiatry to cybernetics to engineering. Warren S. McCulloch (1898–1969) adopted many identities in his scientific life—among them philosopher, poet, neurologist, neurophysiologist, neuropsychiatrist, collaborator, theorist, cybernetician, mentor, engineer. He was, writes Tara Abraham in this account of McCulloch's life and work, “an intellectual showman,” and performed this part throughout his career. While McCulloch claimed a common thread in his work was the problem of mind and its relationship to the brain, there was much more to him than that. In Rebel Genius, Abraham uses McCulloch's life as a window on a past scientific age, showing the complex transformations that took place in American brain and mind science in the twentieth century—particularly those surrounding the cybernetics movement. Abraham describes McCulloch's early work in neuropsychiatry, and his emerging identity as a neurophysiologist. She explores his transformative years at the Illinois Neuropsychiatric Institute and his work with Walter Pitts—often seen as the first iteration of “artificial intelligence” but here described as stemming from the new tradition of mathematical treatments of biological problems. Abraham argues that McCulloch's dual identities as neuropsychiatrist and cybernetician are inseparable. He used the authority he gained in traditional disciplinary roles as a basis for posing big questions about the brain and mind as a cybernetician. When McCulloch moved to the Research Laboratory of Electronics at MIT, new practices for studying the brain, grounded in mathematics, philosophy, and theoretical modeling, expanded the relevance and ramifications of his work. McCulloch's transdisciplinary legacies anticipated today's multidisciplinary field of cognitive science.
Author: P. Michael Conn Publisher: Springer Science & Business Media ISBN: 1592597076 Category : Medical Languages : en Pages : 560
Book Description
A panel of leading experts integrate the latest findings from basic and clinical science to create a comprehensive treatment of the processes by which the brain acts as an endocrine organ, not only to control hormonal functions, but also to maintain homeostasis and regulate behavior. The authors-recognized both as leaders in their fields and as skilled teachers-provide systematic coverage of the analytical, anatomical, functional, clinical, and pathological aspects of neuroendocrinology. Topics range from the interactions between the nervous and endocrine systems to the regulation of reproduction, development, metabolism, fluid balance, and biological rhythms. Neuroendocrinology in Physiology and Medicine offers an unprecedented marriage of clinical and basic knowledge that has been missing from classical neuroscience, endocrinology, and physiology texts. It will teach today's medical students and serve researchers as a valuable reference to this rapidly growing field.
Author: Jeroen Pasterkamp Publisher: Springer Science & Business Media ISBN: 1441903224 Category : Medical Languages : en Pages : 143
Book Description
Theneurotransmitter dopamine has just celebrated its 50thbirthday. The discovery of dopamine as a neuronal entity in the late 1950s and the notion that it serves in neurotransmission has been a milestone in the field of neuroscience research. This milestone marked the beginning of an era that explored the brain as an integrated collection of neuronal systems that one could distinguish on basis of neurotransm- ter identities, and importantly, in which one started to be able to pinpoint the seat of brain disease. The mesodiencephalic dopaminergic (mdDA) system, previously designated as midbraindopaminergic system, has received much attention since its discovery. The initial identification of dopamine as a neurotransmitter in the central nervous system (CNS) and its relevance to psychiatric and neurological disorders have stimulated a plethora of neurochemical, pharmacological and genetic studies into the function of dopamine neurons and theirprojections. In the last decade, studies on gene expression and development have further increased the knowledge of this neuronal population and have unmasked a new level of complexity. The start of the molecular dissection of the mdDA system has been marked by the cloning and characterization ofNurrl and Pitx3. These transcription factors were shown to have a critical function during mdDA development. These initial studies have been followed by the identification of many other proteins, which have a crucial function in the creation of a dopamine neuron permissive region, induction of precursors, induction of terminaldifferent- tion and finally maintenance of the mdDA neuronal pool.
Author: Otto Magnus
Author: Otto Magnus
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Author: National Library of Medicine (U.S.)
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Author: Tara Abraham
Author: Isaac Landman
Author: P. Michael Conn
Author: Jeroen Pasterkamp