Regenerative Medicine for the Inner Ear

Regenerative Medicine for the Inner Ear PDF Author: Juichi Ito
Publisher: Springer
ISBN: 4431548629
Category : Medical
Languages : en
Pages : 311

Book Description
The research described in this book represents important steps toward understanding the development of inner ear medicine and new perspectives in regenerative medicine, including efficacy in cochlear implants and various other treatments. The book depicts the mechanisms that underlie inner ear diseases, their experimental models, and proposals for new strategies to treat their symptoms. As well, the exciting future prospects for dealing with the very common problem of inner ear diseases are explained. These disorders occur among many people and include sensorineural hearing loss (SNHL), sudden deafness, senile deafness, noise-induced deafness, tinnitus, dizziness–vertigo, and Ménière’s disease. In Japan alone, there are more than 6 million deaf patients including those with middle-range deafness. There is currently no effective treatment, and regardless of the underlying cause, the damage has been considered irreversible. However, the results of recent research show that these patients actually can recover. The study of hair cells, spiral ganglion neurons, and stem cells for inner ear diseases such as SNHL, tinnitus, dizziness, and vertigo is at the forefront of regenerative medicine and may provide solutions to some of these problems. The information presented here makes this book a valuable professional reference work for all doctors and researchers in the field of otolaryngology who focus on regenerative treatments for inner ear diseases.

Regenerative Medicine in Otolaryngology

Regenerative Medicine in Otolaryngology PDF Author: Juichi Ito
Publisher: Springer
ISBN: 4431548564
Category : Medical
Languages : en
Pages : 236

Book Description
This book describes an exciting new movement using regenerative medicine to treat patients with otolaryngological diseases. The emerging field of regenerative medicine uses tissue engineering, which combines medicine and engineering not only to treat the diseases themselves but also to enable recovery of the function of affected areas. As otolaryngology covers wide regions, including many diseases of the head and neck, the book is divided into sections, each corresponding to a different anatomical structure — the ear, nose, oral cavity, pharynx, larynx and head and neck. The structural developments of each region, the underlying mechanisms of diseases specific to these regions, their experimental models and proposals for new regenerative treatment are all discussed in detail. The various diseases and symptoms considered in the book include inner ear and middle ear diseases, rhinitis, nasal sinusitis and otolaryngological cancers. To date there have been few clinical studies reporting regenerative medical applications in the field of otolaryngology, but in this volume leading authors present the latest research findings to help provide new therapies for patients in the future. This state-of-the-art information makes the book a valuable professional reference work for all doctors and researchers who focus on regenerative treatments in the field of otolaryngology and neuroscience.

The Mechanism on Development and Regeneration of Inner Ear Hair Cells

The Mechanism on Development and Regeneration of Inner Ear Hair Cells PDF Author: Dongdong Ren
Publisher: Frontiers Media SA
ISBN: 283250003X
Category : Science
Languages : en
Pages : 139

Book Description


Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine PDF Author: Walter C. Low
Publisher: World Scientific
ISBN: 9812775773
Category : Medical
Languages : en
Pages : 571

Book Description
The commercialization of biotechnology has resulted in an intensive search for new biological resources for the purposes of increasing food productivity, medicinal applications, energy production, and various other applications. Although biotechnology has produced many benefits for humanity, the exploitation of the planet's natural resources has also resulted in some undesirable consequences such as diminished species biodiversity, climate change, environmental contamination, and intellectual property right and patent concerns.This book discusses the role of biological, ecological, environmental, ethical, and economic issues in the interaction between biotechnology and biodiversity, using different contexts. No other book has discussed all of these issues in a comprehensive manner. Of special interest is their impact when biotechnology is shared between developed and developing countries, and the lack of recognition of the rights of indigenous populations and traditional farmers in developing countries by large multinational corporations.

Molecular Mechanisms of Auditory Function and Stem Cell Mediated Regeneration of the Inner Ear

Molecular Mechanisms of Auditory Function and Stem Cell Mediated Regeneration of the Inner Ear PDF Author: Michael Stephen Hildebrand
Publisher:
ISBN:
Category : Cochlea
Languages : en
Pages : 538

Book Description


Hair Cell Regeneration

Hair Cell Regeneration PDF Author: Mark E. Warchol
Publisher: Springer Nature
ISBN: 3031206614
Category : Medical
Languages : en
Pages : 242

Book Description
This volume provides a detailed update on progress in the field of hair cell regeneration. This topic is of considerable interest to academicians, clinicians, and commercial entities, including students of auditory and vestibular neuroscience, audiologists, otologists, and industry, all of whom may have interest in hair cell regeneration as a potential future therapy for hearing and balance dysfunction. In 2008, Springer published a SHAR volume on this subject (Hair Cell Regeneration, Repair, and Protection, Editors Richard Salvi and Richard Fay). Since that time, there has been considerable advancement in this field.This book provides a historical perspective on the field, but the emphasis is on more "prospective" views of the various facets of regeneration research, in the hope that the volume will stimulate new projects and approaches, focusing on the limitations of current knowledge and describing promising strategies for future work. The book will include the following key features of hair cell regeneration: • Cellular and molecular control hair cell regeneration in non-mammalian species (in particular zebrafish and chickens) • Our current understanding of the capacity for hair cell replacement in mammals (rodents and humans). • Signals controlling pro-regenerative behaviors in supporting cells, the hair cell progenitors. • New techniques that have been applied to study the genetic and epigenetic regulation of hair cell regeneration in mammals and non-mammals. • Contributions of stem cells toward building new tools to explore how hair cell regeneration is controlled and toward developing cells and tissue for therapeutic transplantation. • Studies that have applied gene and drug therapy to promote regeneration in mammals.

Medical Otology and Neurotology

Medical Otology and Neurotology PDF Author: Mohamed Hamid
Publisher: Thieme
ISBN: 3131610719
Category : Medical
Languages : en
Pages : 405

Book Description
This timely book reflects trends in managing patients with inner ear disease through medical means rather than through surgical treatment. Covering the clinical applications of cutting-edge research, including regenerative medicine for inner ear disease, inner ear perfusion treatments, vestibular rehabilitation for balance retraining, and the use of cochlear implants, this text keeps you abreast of the latest advances and information in the field. You will learn how to diagnose and manage peripheral auditory and vestibular disorders, central vestibular disorders, disorders of the facial nerve, and more. The authors offer insights into the genetics of hearing loss and immune-mediated inner ear disease that help illuminate the underlying principles needed to understand, diagnose and treat dysfunction.Key features: Reviews the fundamental concepts, evaluation and management techniques of inner ear disease and disorders including tinnitus and dysfunction of the Eustachian tube Presents different treatment options based on underlying disease as opposed to symptomatic treatments Discusses the audiometric, vestibular, and laboratory tests that guide the clinician through the early stages of patient care Covers the recent advances in inner ear fluids dynamics and the genetics of hearing loss to provide a more complete understanding of disease and dysfunction Clinicians in the early stages of their careers as well as experts in the field will find the book an excellent reference for clinical and rehabilitation management, as well as for knowledge in the basic and advanced auditory and vestibular sciences and medicine.

Principles of Regenerative Medicine

Principles of Regenerative Medicine PDF Author: Anthony Atala
Publisher: Academic Press
ISBN: 0123814235
Category : Science
Languages : en
Pages : 1203

Book Description
Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Repair and Regeneration in the Inner Ear

Repair and Regeneration in the Inner Ear PDF Author: Jason Robert Meyers
Publisher:
ISBN:
Category :
Languages : en
Pages : 620

Book Description


Ontogeny and Regeneration in the Inner Ear

Ontogeny and Regeneration in the Inner Ear PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 210

Book Description