Recent progress in the study and therapy of brain edema. Proceedings of the 5th International Symposium on Brain Edema...1982 PDF Download

Author: K. G. Go
Publisher:
ISBN:
Category : Cerebral edema
Languages : en
Pages : 0

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Author: K. Go
Publisher: Springer Science & Business Media
ISBN: 1468446169
Category : Science
Languages : en
Pages : 688

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Book Description
This issue contains the proceedings of the most recent Inter national Symposium on Brain Edema, the 5th in a series of confer ences starting 1965 in Vienna. The ever since increasing interest in this field may not only result from the fact that - in clinical terms - the problem is not solved yet, but also from the many fascinating physiological and biochemical questions remaining. Moreover, the rapid progress of technical, physiological and bio chemical developments provides a permanent challenge to probe the subject with better and better resolution. The current proceedings provide many examples. It is safe to assume, that the history of brain edema research is familiar to most of its participants. Therefore, suffice it to remark that since the first histopathological recognition of brain edema as a separate entity among the multitude of intracranial space occupying lesions, progress in the understanding of its pathogenesis has not been straightforward. On the contrary, it has been complicated by confusing notions and concepts, some of which may have resulted from the elusiveness of the edematous changes in early histological studies, due to the inadequacy of the light microscope. Although brain edema occurs concomitantly in many pgtho10gica1 conditions of the brain, it has been suggested that its role is collateral only. Nevertheless, the potential of brain edema as a space occupying lesion is not trivial, since it raises intracranial pressure and eventually may result in lethal cerebral herniation.

Author: K. Go
Publisher:
ISBN: 9781468446173
Category :
Languages : en
Pages : 764

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Author: Umeo Ito
Publisher: Springer Science & Business Media
ISBN: 3709193346
Category : Medical
Languages : en
Pages : 585

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The first international symposium on brain edema was held in Vienna/ Austria in 1965 followed by altogether eight meetings since. The most recent was organized in Y okohama by the Department of Neurosurgery of the Musashino Red Cross Hospital, Tokyo. The continuing interest of both, clinicians and experimental scientists alike may be attributable to the fact that brain edema is a common denominator of many cerebral disorders, which under acute conditions threatens life and weIl-being of afflicted patients. Although progress in understanding as weIl as treatment can be recognized since 1965 many problems remain, particularly concerning the control of brain edema under acute conditions, as in trauma or ischemia. A quantum leap was the distinction of the cytotoxic and vasogenic brain edema prototypes as advanced by Igor Klatzo, providing for transition from a morphological to functional understanding now. The recent brain edema meetings were certainly benefiting from developments of both, molecular neurobiology on the one hand side and functional brain imaging at an ever-increasing resolution on the other, such as magnetic resonance imaging orpositron emission tomography. The international symposium in San Diego 1996 may witness further breakthroughs, hopefully also of effective treatment modalities. The symposium in Y okohama was dedicated to the "Legacy of 28 Years of Brain Edema Research" as a reminder of accomplishments as weIl as remaining challenges.

Author: T. Kuroiwa
Publisher: Springer Science & Business Media
ISBN: 9783211009192
Category : Medical
Languages : en
Pages : 636

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Brain edema is a simple phenomenon – an abnormal increase of brain tissue volume by the increase of brain tissue water content. However the etiology is not simple and relating to a wide variety of neurological disorders including ischemia, trauma, tumor, hemorrhage and hydrocephalus. It is still a major cause of death in the neurological/neurosurgical ward. This volume is an up-to-date report on progress in brain edema research, diagnosis and treatment, including papers presented at the 12th International Symposium on Brain Edema and Brain Tissue Injury in 2002. Major topics include molecular biology and blood-brain barrier disorders, ischemic and traumatic brain edema, imaging and diagnosis of brain edema, treatment and radiation effect. Various papers in the rapidly growing fields of neuroimaging and molecular medicine are also included.

Author: Hanna M. Pappius
Publisher: Springer Science & Business Media
ISBN: 3642665241
Category : Medical
Languages : en
Pages : 456

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A workshop on Dynamic Aspects of Cerebral Edema was organized to pro vide an opport~nitY,for interdisciplinary and detailed consideration of this subject, so crucial in neurology and neurosurgery. The previ ous workshops were held in Vienna in 1965 and in Mainz in 1972. In the meantime, our ideas on mechanisms of resolution of cerebral edema had been changing drastically. Controversy had arisen regarding the role of biogenic amines in the development of edema. Active work in several centers had indicated the possibility of a reversible compo nent in edematous changes associated with ischemia, the control of which could be of therapeutic significance in the problem of stroke. It was felt that a thorough discussion, at this time, by those involv ed in these various studies should help to resolve the controversies, to crystallize the implications of the new findings, and to evaluate their application for patient care. In preparing the proceedings for publication we have edited the manu scripts and selected the discussions with an aim to highlight new find ings, to make this volume readable, and to eliminate duplication. We gratefully acknowledge financial support from the institutions and organizations previously listed. Many individuals contributed to the success of the workshop and the preparation of the proceedings for publication. Doctors J.B. Brierley, I. Klatzo, H.J. Reulen, and A.G.

Author: Hans J. Reulen
Publisher: Springer Science & Business Media
ISBN: 3642654487
Category : Medical
Languages : en
Pages : 360

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The control of brain edema is still one of the major problems in surgical and conservative treatment of various cerebral lesions. Many attempts have been made to develop methods for reducing the high mortality associated with brain edema. Mter many years of using hypertonic solutions it can be stated that this type of therapy has not yielded satisfactory results. During recent years increasing evidence has been accumulated on the efficacy of steroids on brain edema. Steroids were reported to result in rapid relief of signs and symptoms of increased intracranial pressure and neurological dysfunction accompanying cerebral edema. It was the aim of this workshop to evaluate the effect of corticosteroids on brain edema as an advance in therapy. It was hoped that this could be achieved by a multi disciplinary approach. Though, the volume contains the contributions of various experts - internists, neurochemists, neurologists, neuropathologists, neurosurgeons, pharmacologists, physiologists - who have added considerable experimental and clin ical evidence on the action of steroids on brain edema. New pathophysiological aspects regarding the mechanisms underlying the formation and resolution of brain The effectiveness of corticosteroid therapy in various forms edema are presented. of clinical and experimental brain edema, e. g. accompanying brain tumors, head injury, spinal cord injury, cerebrovascular lesions, etc. as well as dosage and duration of treatment are critically discussed.

Author: Umeo Ito
Publisher: Springer Verlag
ISBN: 9780387825328
Category : Medical
Languages : en
Pages : 589

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Author: A. Hartmann
Publisher: Springer
ISBN: 9783540117513
Category : Medical
Languages : de
Pages : 176

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This book contains the papers delivered at the Symposium on "Medical Treatment of Brain Ede ma" at the Seventh International Congress ofNeu rological Surgery, held in Munich in 1981. The aim of each speaker was to give a short review of current knowledge in his or her field. In addition, most of the authors presented their own data. The symposium . was divided into two parts. The experimental part focused on pathophysiological and biochemical findings, while the clinical part dealt with therapy for brain edema, with particular emphasis on steroids. We wish to acknowledge the technical support of Springer-Verlag, Merck Company, Darmstadt and the help of Miss Scholz, Secretary of the Depart ment of Neurology at the University of Heidel berg. Heidelberg/Berlin A. Hartmann M. Brock v Contents K. -A. Hossmann Pathophysiology of Va so genic and Cytotoxic Brain Edema . . . . . . . . . . . . . . . . . . . A. Marrnarou, K. Tanaka, and K. Shulmann The Brain Response to Infusion Edema: Dynamics of Fluid Resolution . . . . . . . . . . 11 M. D. O'Brien 19 Ischemic Cerebral Edema A. Baethmann, W Oettinger, K. Moritake, L. Chaussy, andF. Jesch Metabolic Effects of Corticosteroids in Central Nervous Tissue . . . . . . . . . . . . . 24 K. Maier-Hauff, O. Kempski, A. Unterberg, U. Gross, M. Lange, L. Schurer, and A. Baethmann The Kallikrein-Kinin-System as Mediator in Cerebral Edema, Recent Progress . . . . . . . . . . . . . 31 S. F. Berndt 36 Symptoms of Cerebral Edema W R. Lanksch The Diagnosis of Brain Edema by Computed Tomography . . . . . . . . . . . . . . 43 H. J. Klein and K. Schmidt Hyperosmolar Solutions and Diuretics in the Treatment of Brain Edema . . . . . . . .

Author: H.E. James
Publisher: Springer
ISBN: 9783709168387
Category : Medical
Languages : en
Pages : 302

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This volume is a compilation of papers presented at the Tenth International Symposium on Brain Edema held on October 20-23, 1996, in San Diego, California. This follows the sequence of meetings that was initiated 31 years ago in the First International Symposium held in Vienna. Subsequent symposiums were held in Mainz, Montreal, Berlin, Groningen, Tokyo, Baltimore, Bern, and Tokyo CY okohama). A considerable number of papers was chosen from over 100 papers that were received. The organizers wish to thank the Advisory Committee for the excellent work done in selection of the papers. We also wish to thank all the persons who contributed to the success of the Tenth International Symposium, especially the staff who worked behind the scenes. These papers were reviewed, edited, approved or disapproved by the Editorial Board. Those manuscripts that were felt not pertinent to this publication were not accepted by the Editorial Board. Therefore, the excellent quality of those that are in the book are a reflection of the authors' dedication and work and that of those of the Editorial Board in their review process. For the reader's convenience, the papers are structured according to the various disease processes which are associated with the primary topic: hypertension, hydrocephalus, infection, ischemia, tumor, etc. We do hope that the reader will enjoy the articles and that they will provide an impetus and insight for future work.