Recent Progress in the Chemical Synthesis of Antibiotics and Related Microbial Products PDF Download

Author: Gabor Lukacs
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 990

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Author: G. Lukacs
Publisher:
ISBN: 9783642782510
Category : Antibiotics
Languages : en
Pages : 984

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Author: Gabor Lukacs
Publisher: Springer
ISBN: 9783540567547
Category : Science
Languages : en
Pages : 970

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Volume 1 published under the title: Recent progress in the chemical synthesis of antibiotics.

Author: Gabor Lukacs
Publisher: Springer
ISBN: 9783642782503
Category : Science
Languages : en
Pages : 0

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Author: Kirk-Othmer
Publisher: John Wiley & Sons
ISBN: 047148508X
Category : Science
Languages : en
Pages : 886

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The fifth edition of the Kirk-Othmer Encyclopedia of Chemical Technology builds upon the solid foundation of the previous editions, which have proven to be a mainstay for chemists, biochemists, and engineers at academic, industrial, and government institutions since publication of the first edition in 1949. The new edition includes necessary adjustments and modernisation of the content to reflect changes and developments in chemical technology. Presenting a wide scope of articles on chemical substances, properties, manufacturing, and uses; on industrial processes, unit operations in chemical engineering; and on fundamentals and scientific subjects related to the field. The Encyclopedia describes established technology along with cutting edge topics of interest in the wide field of chemical technology, whilst uniquely providing the necessary perspective and insight into pertinent aspects, rather than merely presenting information. * Set began publication in January 2004 * Over 1,000 articles * More than 600 new or updated articles * 27 volumes

Author: National Research Council
Publisher: National Academies Press
ISBN: 0309168392
Category : Science
Languages : en
Pages : 238

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Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.

Author: François Diederich
Publisher: John Wiley & Sons
ISBN: 3527613536
Category : Science
Languages : en
Pages : 431

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Template-controlled reactions allow the synthesis of complex molecules which would hardly be achievable through classical methods. This handbook offers authoratative information on how noncovalent and covalent templates can be effectively applied to control reaction rates as well as regio- and stereoselectivity. From the concepts of template control such as molecular imprinting, self-replication, and reversible tether-directed remote functionalization, the reader is led to template-based ring-closing reactions, oligomerizations, and multiple functionalizations and their application in the synthesis of supramolecular scaffolds and natural products. The editors and authors (J. F. Stoddart, G. Wulf, D. Lynn, R. Breslow. F. Diederich, just to name a few ) , all internationally recognized experts in their area, succeeded in presenting the manifold aspects of template-controlled synthesis in a didactic way, making this methodology accessible to a broad readership of organic synthetic chemists. Well-selected, reliable key experimental protocols and an up-to-date reference list underline the practical approach of this valuable handbook. Being the first book of its kind, it will serve as a pacemaker and stimulate future research.

Author: Jun Lin
Publisher: Frontiers Media SA
ISBN: 2889195260
Category : Antibiotics
Languages : en
Pages : 226

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Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

Author: E. J. Corey
Publisher: John Wiley & Sons
ISBN: 1118361733
Category : Science
Languages : en
Pages : 272

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Book Description
Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.

Author: Thomas J. Dougherty
Publisher: Springer Science & Business Media
ISBN: 1461414008
Category : Medical
Languages : en
Pages : 1119

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Book Description
This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.