Rapid Sample Preparation Methods for Use With High Speed Gas Chromatography PDF Download

Author: Robert W. Current, Ph.D.
Publisher: Robert Current
ISBN:
Category : Gas chromatography
Languages : en
Pages : 312

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Author: Katja Dettmer-Wilde
Publisher: Springer
ISBN: 3642546404
Category : Science
Languages : en
Pages : 904

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Book Description
Gas chromatography continues to be one of the most widely used analytical techniques, since its applications today expand into fields such as biomarker research or metabolomics. This new practical textbook enables the reader to make full use of gas chromatography. Essential fundamentals and their implications for the practical work at the instrument are provided, as well as details on the instrumentation such as inlet systems, columns and detectors. Specialized techniques from all aspects of GC are introduced ranging from sample preparation, solvent-free injection techniques, and pyrolysis GC, to separation including fast GC and comprehensive GCxGC and finally detection, such as GC-MS and element-specific detection. Various fields of application such as enantiomer, food, flavor and fragrance analysis, physicochemical measurements, forensic toxicology, and clinical analysis are discussed as well as cutting-edge application in metabolomics is covered.

Author: Robert L. Grob, PhD
Publisher: John Wiley & Sons
ISBN: 047165115X
Category : Science
Languages : en
Pages : 1059

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Book Description
The bible of gas chromatography-offering everything the professional and the novice need to know about running, maintaining, and interpreting the results from GC Analytical chemists, technicians, and scientists in allied disciplines have come to regard Modern Practice of Gas Chomatography as the standard reference in gas chromatography. In addition to serving as an invaluable reference for the experienced practitioner, this bestselling work provides the beginner with a solid understanding of gas chromatographic theory and basic techniques. This new Fourth Edition incorporates the most recent developments in the field, including entirely new chapters on gas chromatography/mass spectrometry (GC/MS); optimization of separations and computer assistance; high speed or fast gas chromatography; mobile phase requirements: gas system requirements and sample preparation techniques; qualitative and quantitative analysis by GC; updated information on detectors; validation and QA/QC of chromatographic methods; and useful hints for good gas chromatography. As in previous editions, contributing authors have been chosen for their expertise and active participation in their respective areas. Modern Practice of Gas Chromatography, Fourth Edition presents a well-rounded and comprehensive overview of the current state of this important technology, providing a practical reference that will greatly appeal to both experienced chomatographers and novices.

Author: Harold M. McNair
Publisher: John Wiley & Sons
ISBN: 111945073X
Category : Science
Languages : en
Pages : 288

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Book Description
Basic Gas Chromatography, Third Edition provides a brief introduction to GC following the objectives for titles in this series. It should appeal to readers with varying levels of education and emphasizes a practical, applied approach to the subject. : This book provides a quick need-to-know introduction to gas chromatography; still the most widely used instrumental analysis technique, and is intended to assist new users in gaining understanding quickly and as a quick reference for experienced users. The new edition provides updated chapters that reflect changes in technology and methodology, especially sample preparation, detectors and multidimensional chromatography. The book also covers new detectors recently introduced and sample preparation methods that have become much more easily accessible since the previous edition.

Author: Serban C. Moldoveanu
Publisher: Elsevier
ISBN: 0323898203
Category : Science
Languages : en
Pages : 698

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Book Description
Modern Sample Preparation for Chromatography, Second Edition explains the principles of sample preparation for chromatographic analysis. A variety of procedures are applied to make real-world samples amenable for chromatographic analysis and to improve results. This book's authors discuss each procedure’s advantages, disadvantages and their applicability to different types of samples, along with their fit for different types of chromatographic analysis. The book contains numerous literature references and examples of sample preparation for different matrices and new sections on green approaches in sample preparation, progress in automation of sample preparation, non-conventional solvents for LLE (ionic liquids, deep eutectic mixtures, and others), and more. Presents numerous techniques applied for sample preparation for chromatographic analysis Provides an up-to-date source of information regarding the progress made in sample preparation for chromatography Describes examples for specific types of matrices, providing a guide for choosing the appropriate sample preparation method for a given analysis

Author: Foujan Falaki
Publisher:
ISBN:
Category : Electronic books
Languages : en
Pages : 0

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Book Description
In gas chromatography (GC), the sample is vaporized and injected onto the head of a chromatographic column. Elution is brought about by the flow of an inert gaseous mobile phase such as helium, argon, nitrogen, carbon dioxide, and hydrogen. In GC, the mobile phase does not interact with molecules of the analyte, and it only transports the analyte through the column. In two general kinds of GC, gas-solid chromatography (GSC) and gas-liquid chromatography (GLC), the mechanisms of analyte retention in the column are thoroughly different. In GLC, the analyte has been participated between a gaseous mobile phase and a liquid stationary phase. While in GSC, the retention of analytes is the consequence of its physical adsorption onto a solid stationary phase. In comparing of GLC and GSC, more widespread use of GLC has been found in all fields of science. This is mainly due to the semipermanent retention of active or polar molecules and the severe tailing of elution peaks, which is a consequence of the nonlinear character of adsorption process, in GSC. In GC, column efficiency requires that sample be of suitable size and be introduced as a plug of vapor. So, the sample preparation is a very important step in GC. The sample should be injected into a flash vaporizer port located at the head of the column, and its temperature is about 50°C above the boiling point of the least volatile component of the sample. So, the components of the sample should be easily vaporized in this temperature, and they should have high heat resistance not to be decomposed. Both of liquid and solid samples can be introduced to the column. But solid samples are ordinarily introduced as solutions or sealed into thin-walled vials that can be inserted at the head of the column and punctured or crushed from the outside. In order to separate and analyze the gaseous, liquid, and volatile solid samples directly, GC is a suitable analytical equipment. When the analyte sample is nonvolatile, the derivatization and pyrolysis GC techniques are crucial. Gas chromatography can be applied to the solution of many problems in various fields such as drugs and pharmaceuticals, environmental studies like air and clinical samples, petroleum industry, pesticides and their residues, and foods. On the other hand, most samples are not ready for direct introduction into instruments. For organics and volatile organics, the sample preparation procedures can be named as extraction, cleanup, derivatization, transfer to vapor phase, and concentration. So, the basic concept of a sample preparation method is to convert a real matrix into a sample in a format that is suitable for analysis by a separation or other analytical techniques. The goals of sample treatment step are as follows: (1) The capability of using smaller amounts of initial sample, especially for trace analysis. (2) Achieving higher specificity and selectivity in analytical determinations. (3) To improve the potential for automation or online methods and minimize the manual operations. (4) The usage of no or small volumes of organic solvents in order to approach the green chemistry techniques with less wastes and more friendly environment. On the other hand, different samples possess a variety of sample treatment methods, for example: (1) In order to treat solid samples and separate a purpose analyte, some enhanced solvent extraction methods include pressurized liquid extraction, microwave- and sonic wave-assisted extraction, supercritical fluid extraction, and superheated water extraction. (2) For analytes in solution, the sample preparation can be attributed to the analyte trapping methods such as -phase extraction, solid-phase microextraction, and stir bar extractions. (3) Also, the extraction of the analytes into a liquid phase can be achieved by other methods like membrane extraction, single-drop microextraction (SDME), and purge and trap. (4) For separation of analytes in the gas phase, trapping analytes from vapor samples and headspace analysis are used. As a result, sample preparation is not only a critical step but also possesses different ways to treat and convert matrix into a suitable sample to inject GC.

Author: Janusz Pawliszyn
Publisher: Elsevier
ISBN: 9780444505101
Category : Science
Languages : en
Pages : 1170

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Book Description
This title is the first comprehensive book on sampling and modern sample preparation techniques and has several main objectives: to facilitate recognition of sample preparation as both an integral part of the analytical process; to present a fundamental basis and unified theoretical approach for the professional development of sample preparation; to emphasize new developments in sample preparation technology; and to highlight the future impact of sample preparation on new directions in analytical science, particularly automation, miniaturization and field implementation. Until recently, there has been relatively little scientific interest in sampling and sample preparation, however this situation is presently changing as sampling and sample preparation become integral parts of the analytical process with their own unique challenges and research opportunities. Sampling and Sample Preparation for Field and Laboratory is an essential resource for all analytical chemists, and in particular those involved in method development. Not only does it cover the fundamental aspects of extraction, it also covers applications in various matrices and includes sampling strategies and equipment and how these can be integrated into the analytical process for maximum efficiency.

Author: Francisco Pena Pereira
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110427265
Category : Science
Languages : en
Pages : 411

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Book Description
Miniaturization is a challenge thrown down to analytical chemistry. The replacement of conventional analytical systems by miniaturized alternatives during the last years is noticeable. Specifically, the miniaturization of traditional sample preparation techniques (e.g., solid-phase extraction or solvent extraction) led to the development of environmentally benign analytical methods. This book aims to provide an overview of the challenges and achievements inthe application of the miniaturized sample preparation methods in analytical laboratories. It includes both theoretical and practical aspects of miniaturized sample preparation approaches and hence should be of interest to researchers, students and teachers of analytical and bioanalytical chemistry, environmental sciences and environmental engineering.

Author: Brian Stuart
Publisher: Royal Society of Chemistry
ISBN: 9780854044788
Category : Education
Languages : en
Pages : 52

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Book Description
This book looks at gas chromatography, the most widely used technique in analytical chemistry.

Author: Jacobus Albertus de Koning
Publisher:
ISBN:
Category :
Languages : en
Pages : 252

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Book Description