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Author: Richard E. Carson Publisher: Elsevier ISBN: 0080540112 Category : Science Languages : en Pages : 535
Book Description
This book presents the latest scientific developments in the field of positron emission tomography (PET) dealing with data acquisition, image processing, applications, statistical analysis, tracer development, parameter estimation, and kinetic modeling. It covers improved methodology and the application of existing techniques to new areas. The text also describes new approaches in scanner design and image processing, and the latest techniques for modeling and statistical analyses. This volume will be a useful reference for the active brain PET scientist, as well as a valuable introduction for students and researchers who wish to take advantage of the capabilities of PET to study the normal and diseased brain. Authored by international authorities in PET Provides the latest up-to-date techniques and applications Covers all fundamental disciplines of PET in one volume A comprehensive resource for students, clinicians, and new PET researchers
Author: Richard E. Carson Publisher: Elsevier ISBN: 0080540112 Category : Science Languages : en Pages : 535
Book Description
This book presents the latest scientific developments in the field of positron emission tomography (PET) dealing with data acquisition, image processing, applications, statistical analysis, tracer development, parameter estimation, and kinetic modeling. It covers improved methodology and the application of existing techniques to new areas. The text also describes new approaches in scanner design and image processing, and the latest techniques for modeling and statistical analyses. This volume will be a useful reference for the active brain PET scientist, as well as a valuable introduction for students and researchers who wish to take advantage of the capabilities of PET to study the normal and diseased brain. Authored by international authorities in PET Provides the latest up-to-date techniques and applications Covers all fundamental disciplines of PET in one volume A comprehensive resource for students, clinicians, and new PET researchers
Author: Publisher: Elsevier ISBN: 0080540104 Category : Medical Languages : en Pages : 481
Book Description
Functional imaging of the brain is one of the most rapidly advancing areas of neuroscience and Positron Emission Tomography (PET) plays a major role in this progress. This book provides a comprehensive overview of the current status of PET and state-of-the-art neuroimaging. It is comprised of summaries of the presentations by experts in the field. Topics covered include radiotracer selection, advances in instrumentation, image reconstruction and data analysis, and statistical mapping of brain activity. This book focuses on the accuracy of the functional image and the strategies for addressing clinical, scientific, and diagnostic questions. Covers the PET imaging process from tracer selection to analysis and interpretation Contains 79 concise reports with abundant illustrations The definitive state-of-the-art book for functional neuroscience with PET
Author: Pablo Aguiar Publisher: LAP Lambert Academic Publishing ISBN: 9783838386751 Category : Languages : en Pages : 188
Book Description
This work is focused on the development of processing, quantification and standarization methods, aimed at enhancing the quality and accuracy of Positron Emission Tomography (PET) images, both for human brain studies and for high-resolution small animal studies. Firstly, the effects of scatter, reconstruction method, anatomical variability, positron range, partial volume effect and non-colinearity on the quantification of PET studies are investigated. Several correction methods for the essential degradations are presented. Finally, the suitability of Monte Carlo techniques for simulating PET studies is also assessed.
Author: Magdy M. Khalil Publisher: Springer Nature ISBN: 3030652459 Category : Medical Languages : en Pages : 571
Book Description
This book provides comprehensive and detailed information on the scientific bases of nuclear medicine, addressing a wide variety of topics and explaining the concepts that underlie many of the investigations and procedures performed in the field. The book is divided into six sections that cover the physics and chemistry of nuclear medicine besides associated quality assurance/quality control procedures; dosimetry and radiation biology; SPECT and PET imaging instrumentation plus CT imaging technology in hybrid modalities; data analysis including image processing, reconstruction, radiomics, image degrading correction techniques, along with image quantitation and kinetic modeling. Within these sections, particular attention is paid to recent developments and the advances in knowledge that have taken place since release of the first edition in 2011. Several entirely new chapters have been included and the remaining chapters, thoroughly updated. Innovations in the ever-expanding field of nuclear medicine are predominantly due to integration of the basic sciences with complex technological advances. This excellently illustrated book on the subject will be of interest to not only nuclear medicine physicists and physicians but also clinical scientists, radiologists, radiopharmacists, medical students and technologists.
Author: Xiujuan Zheng Publisher: ISBN: Category : Tomography, Emission Languages : en Pages : 152
Book Description
Furthermore, the frequent invasive arterial blood sampling to obtain input function poses many challenges and inconvenience for tracer kinetic modeling with dynamic PET imaging. Non-invasive approaches were proposed to address this issue. A simple non-invasive quantification method based on Patlak graphic analysis (PGA) that uses a reference region to obtain the relative influx rate without an input function has recently been proposed. This non-invasive Patlak (nPGA) method was extended to whole-body FDG-PET studies and systematically investigated using a set of mouse studies and computer simulations. In the mouse studies, a high linearity of relative influx rates was observed between the nPGA and PGA for most pairs of reference and target regions, when an appropriate underlying kinetic model was used. The simulation results demonstrated that the accuracy of the nPGA method was similar to that of the PGA method, with a higher reliability for most pairs of reference and target regions. The results proved that the nPGA method could provide a non-invasive and indirect way of quantifying the FDG kinetics in the tissues where the k4 and vascular effect were negligible. The automatic non-invasive approach can further facilitate the analysis of dynamic PET imaging. A novel hybrid clustering method (HCM) was proposed to objectively delineate the regions of interest (ROIs) in dynamic PET images for the automatic estimation of image-derived input function (IDIF) and was demonstrated the application to the mouse FDG-PET studies. The results showed that the HCM achieved accurate ROIs delineation in both computer simulations and experimental mouse studies. In the mouse studies the predicted IDIF had a high correlation with the gold standard, the PTAC derived from invasive blood sampling. The results indicate that the proposed HCM has a great potential in ROI delineation for automatic estimation of IDIF in dynamic FDG-PET studies. In summary, this thesis has significantly contributed to the improvement of several critical quantification approaches for preclinical small-animal studies and clinical patient examinations.
Author: Claus Grupen Publisher: Springer Science & Business Media ISBN: 3642132715 Category : Science Languages : en Pages : 1251
Book Description
The handbook centers on detection techniques in the field of particle physics, medical imaging and related subjects. It is structured into three parts. The first one is dealing with basic ideas of particle detectors, followed by applications of these devices in high energy physics and other fields. In the last part the large field of medical imaging using similar detection techniques is described. The different chapters of the book are written by world experts in their field. Clear instructions on the detection techniques and principles in terms of relevant operation parameters for scientists and graduate students are given.Detailed tables and diagrams will make this a very useful handbook for the application of these techniques in many different fields like physics, medicine, biology and other areas of natural science.
Author: Committee on the Mathematics and Physics of Emerging Dynamic Biomedical Imaging Publisher: National Academies Press ISBN: 0309552923 Category : Science Languages : en Pages : 261
Book Description
This cross-disciplinary book documents the key research challenges in the mathematical sciences and physics that could enable the economical development of novel biomedical imaging devices. It is hoped that the infusion of new insights from mathematical scientists and physicists will accelerate progress in imaging. Incorporating input from dozens of biomedical researchers who described what they perceived as key open problems of imaging that are amenable to attack by mathematical scientists and physicists, this book introduces the frontiers of biomedical imaging, especially the imaging of dynamic physiological functions, to the educated nonspecialist. Ten imaging modalities are covered, from the well-established (e.g., CAT scanning, MRI) to the more speculative (e.g., electrical and magnetic source imaging). For each modality, mathematics and physics research challenges are identified and a short list of suggested reading offered. Two additional chapters offer visions of the next generation of surgical and interventional techniques and of image processing. A final chapter provides an overview of mathematical issues that cut across the various modalities.
Author: Richard E. Carson
Author: Richard E. Carson
Author: 
Author: Pablo Aguiar
Author: Ramsey D. Badawi
Author: Magdy M. Khalil
Author: Xiujuan Zheng
Author: Claus Grupen
Author: Ulla Ruotsalainen
Author: Committee on the Mathematics and Physics of Emerging Dynamic Biomedical Imaging
Author: Dale L. Bailey