Proceedings of the National Seminar on Biomarkers: From Research to Clinical Practice (BRCP–2017) PDF Download
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Author: Mrs. M. Divya Publisher: Allied Publishers ISBN: 9387380289 Category : Technology & Engineering Languages : en Pages : 156
Book Description
In medicine, a biomarker can be a traceable substance that is introduced into an organism to examine organ function or other aspects of health. Biomarkers are compounds, isolated from serum, urine, or other fluids. They can be used as an indicator of the presence or severity of a particular disease. Biomarkers help in disease prevention, early diagnosis, drug target identification, drug response, etc. Biomarkers play a critical role in improving the drug development process and biomedical research. To throw light on these perspectives and to understand the role of biomarkers in clinical research, this seminar is organized. Thrust areas of the seminar are: • Disease related biomarkers • Clinical drug development biomarkers • Novel biomarkers.
Author: Mrs. M. Divya Publisher: Allied Publishers ISBN: 9387380289 Category : Technology & Engineering Languages : en Pages : 156
Book Description
In medicine, a biomarker can be a traceable substance that is introduced into an organism to examine organ function or other aspects of health. Biomarkers are compounds, isolated from serum, urine, or other fluids. They can be used as an indicator of the presence or severity of a particular disease. Biomarkers help in disease prevention, early diagnosis, drug target identification, drug response, etc. Biomarkers play a critical role in improving the drug development process and biomedical research. To throw light on these perspectives and to understand the role of biomarkers in clinical research, this seminar is organized. Thrust areas of the seminar are: • Disease related biomarkers • Clinical drug development biomarkers • Novel biomarkers.
Author: Alison Keen Publisher: John Wiley & Sons ISBN: 1444340131 Category : Medical Languages : en Pages : 276
Book Description
Patients with breast and gynaecological cancers have to contend with a large number of difficult and challenging issues. To help them to do this it is vital that their health carers are fully informed in all aspects of women's cancers. This book provides a comprehensive and meaningful picture of this oncological area, including epidemiology, histopathology, staging, genetic predisposition, sexual function, fertility, treatment and management, survivorship, and palliative care. To give this book added credibility and holistic application, contributions of women with cancer have been included, and the text is interspersed with patient accounts and experiences. Women's Cancers is essential reading for all nurses and health care professionals working in cancer care settings, as well as patients and families.
Author: William E. Dismukes Publisher: ISBN: 0195148096 Category : Medical Languages : en Pages : 534
Book Description
Within the field of infectious diseases, medical mycology has experienced significant growth over the last decade. Invasive fungal infections have been increasing in many patient populations, including: those with AIDS; transplant recipients; and the elderly. As these populations grow, so does the diversity of fungal pathogens. Paralleling this development, there have been recent launches of several new antifungal drugs and therapies. Clinical Mycology offers a comprehensive review of this discipline. Organized by types of fungi, this volume covers microbiologic, epidemiologic and demographic aspects of fungal infections as well as diagnostic, clinical, therapeutic, and preventive approaches. Special patient populations are also detailed.
Author: Hardy J. Rideout Publisher: Springer ISBN: 3319499696 Category : Medical Languages : en Pages : 280
Book Description
This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.
Author: Jun Zhou Publisher: Humana Press ISBN: 9781617796647 Category : Medical Languages : en Pages : 492
Book Description
Chemotherapy is one of the major treatment options for cancer patients; however, the efficacy of chemotherapeutic management of cancer is severely limited by multidrug resistance, in that cancer cells become simultaneously resistant to many structurally and mechanistically unrelated drugs. In the past three decades, a number of mechanisms by which cancer cells acquire multidrug resistance have been discovered. In addition, the development of agents or strategies to overcome resistance has been the subject of intense study. This book contains comprehensive and up-to-date reviews of multidrug resistance mechanisms, from over-expression of ATP-binding cassette drug transporters such as P-glycoprotein, multidrug resistance-associated proteins, and breast cancer resistance p- tein to the drug ratio-dependent antagonism and the paradigm of cancer stem cells. The book also includes strategies to overcome multidrug resistance, from the development of compounds that inhibit drug transporter function to the modulation of transporter expression. In addition, this book contains techniques for the detection and imaging of drug transporters, methods for the investigation of drug resistance in animal models, and strategies to evaluate the efficacy of resistance reversal agents. The book intends to provide a state-of-the-art collection of reviews and methods for both basic and clinician investigators who are interested in cancer multidrug resistance mechanisms and reversal strategies. Tianjin, China Jun Zhou v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix 1 Multidrug Resistance in Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Bruce C. Baguley 2 Multidrug Resistance in Oncology and Beyond: From Imaging of Drug Efflux Pumps to Cellular Drug Targets . . . . . . . . . . . . . . . . . . . . . . . . . .
Author: Kevin M. Haigis, Ph.D. Publisher: Springer Science & Business Media ISBN: 146148412X Category : Medical Languages : en Pages : 319
Book Description
Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. The book will focus on the progression from the identification of mutations that drive colorectal cancer initiation and progression to the search for novel therapies to treat the disease.
Author: Paul P. Glasziou Publisher: John Wiley & Sons ISBN: 0470695617 Category : Medical Languages : en Pages : 376
Book Description
Monitoring is a major component of management of chronic diseases such as diabetes, cardiovascular disease, arthritis and depression. Yet poor monitoring means healthcare costs are rising. This book discusses how monitoring principles adopted in other spheres such as clinical pharmacology and evidence-based medicine can be applied to chronic disease in the global setting. With contributions from leading experts in evidence-based medicine, it is a ground-breaking text for all involved in delivery of better and more effective management of chronic illnesses.
Author: Eng H. Lo Publisher: Springer Science & Business Media ISBN: 1461486904 Category : Medical Languages : en Pages : 523
Book Description
While there are a number of books on the market that deal with neuronal mechanisms and targets, the proposed book will be the only one to cover the vascular aspects of CNS trauma. The contributing authors will present basic mechanisms, explain cutting-edge experimental models and techniques, and provide several clinical chapters that provide treating physicians with some insight on the cases that they see in the ICU. The table of contents is diverse and comprehensive with chapters on molecular mechanisms, physiology, pharmacology, stem cells, genomics and proteomics, in vivo MRI and PET, as well as the clinical management of vascular parameters.
Author: Mrs. M. Divya
Author: Mrs. M. Divya
Author: Burzynski Research Institute
Author: Alison Keen
Author: John Timothy Allen
Author: William E. Dismukes
Author: Hardy J. Rideout
Author: Jun Zhou
Author: Kevin M. Haigis, Ph.D.
Author: Paul P. Glasziou
Author: Eng H. Lo