Primary Biliary Cholangitis, An Issue of Clinics in Liver Disease PDF Download

Author: Binu V. John
Publisher: Elsevier Health Sciences
ISBN: 0323972950
Category : Medical
Languages : en
Pages : 249

View

Book Description
In this issue of Clinics in Liver Disease, guest editor Dr. John V. Binu brings his considerable expertise to the topic of Primary Biliary Cholangitis. PBC leads to inflammation and scarring of the small bile ducts, and, if untreated, can lead to cirrhosis and liver failure. In this issue, top experts provide a state-of-the-art review of diagnosis and treatment for this chronic, progressive liver disorder. - Contains 13 practice-oriented topics including genetics of primary biliary cholangitis; prognostic scoring systems in PBC; overlap syndromes and PBC; non-invasive evaluation of fibrosis and portal hypertension in PBC; treatment of PBC: first- and second-line therapies; novel therapies for PBC; and more. - Provides in-depth clinical reviews on primary biliary cholangitis, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author: Elizabeth J Carey
Publisher: Elsevier Health Sciences
ISBN: 0323613950
Category : Medical
Languages : en
Pages : 217

View

Book Description
The Guest Editors have put together an issue of clinical reviews that provides the most current look at PBC. Authors, all experts in their respective areas, have submitted articles in the following areas: Changes in epidemiology of PBC; Genetic and epigenetics in PBC; Role of bile acids and the bicarbonate umbrella in the pathogenesis of PBC; Current treatment options in PBC; Work in progress: Drugs in development; Natural history of PBC in the UDCA era: Role of scoring systems; Treatment of Pruritus: Tricks of the trade; Chronic complications of cholestasis: Work-up and Management; Individualizing care: Management beyond medical therapy; Role of liver biopsy: When to do, how to stage; AMA-negative PBC: Is it really the same as AMA-positive PBC?; New thoughts on Overlap syndrome with auto-immune hepatitis; and Current status of liver transplantation for PBC.

Author: Steven L. Flamm
Publisher: Elsevier Health Sciences
ISBN: 0323354610
Category : Medical
Languages : en
Pages : 241

View

Book Description
Dr. Flamm has invited a group of distinguished hepatologists to provide insight into the assessment of a variety of scenarios where clinical judgment based on experience and published literature is an invaluable addition to the care of individual patients. Articles included in the issue address the following topics: Evaluation and Management of Portal Vein Thrombosis, Liver Disease in the HIV patient, Hepatocellular Carcinoma, Evaluation of Renal Insufficiency in the Cirrhotic Patient, Contemporary Management of Autoimmune Hepatitis, Diagnosis and Treatment of Overlap Syndromes, Ins and Outs of Liver Imaging for the Gastroenterologist, Contemporary Assessment of Hepatic Fibrosis, A Primer on Liver Transplantation Immunosuppressive Agents for the Gastroenterologist, Evaluation of Jaundice in the Hospitalized Patient, Liver Disease in the Adolescent, Evaluation and Management of Hemochromatosis and How and When to Administer Hepatitis A and B Virus Vaccinations. These are all common contemporary reasons for consultations for Gastroenterologists and Hepatologists and this issue will address the issues in a pragmatic way.

Author: Cynthia Levy
Publisher: Elsevier Health Sciences
ISBN: 0323429920
Category : Medical
Languages : en
Pages : 225

View

Book Description
Dr. Levy has secured the field’s top experts to offer the latest clinical reviews on cholestatic liver disease. The issue will include articles devoted to The Gut-Liver Axis; Update on Genetics in Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis; New thoughts on IgG4 Associated Cholangitis; Cancer Risk and Surveillance in PSC; Novel Therapies for PBC; and Liver transplantation for Cholestatic Liver Diseases, to name a few. Dr. Levy’s issue will be the most current authority on cholestatic liver disease.

Author: Elizabeth J. Carey
Publisher: Springer
ISBN: 1493910132
Category : Medical
Languages : en
Pages : 265

View

Book Description
Since the publication of the first edition, there have been advances in both the diagnosis and the management of many of the cholestatic liver diseases. Cholestatic Liver Disease, Second Edition thoroughly updates the topics previously addressed, such as primary biliary cirrhosis, primary sclerosing cholangitis and cholestatic variants of drug hepatotoxicity and viral disease. New treatments, such as the development of the farnesoid X receptor agonists for the treatment of PBC, are highlighted. Current guidelines and areas of uncertainty are also covered. Additionally, new chapters have been added to reflect the changing landscape of cholestatic liver disease. Cholestatic Liver Disease, Second Edition is a concise yet comprehensive summary of the current status of the field and is of value to clinicians and researchers interested in patients with cholestatic liver disease provide that will help to guide patient management and stimulate investigative efforts.

Author: Cynthia Levy
Publisher: Elsevier Health Sciences
ISBN: 1455771996
Category : Medical
Languages : en
Pages : 244

View

Book Description
Dr. Levy is a key leader in the field of hepatology , and she has enlisted authors who are top experts in their fields to submit state-of-the-art clinical reviews on cholestatic liver diseases. Articles are devoted to genetic determinants of cholestasis, nuclear receptors as drug targets, drug-induced cholestasis, primary sclerosing cholangitis, therapeutic advances in primary biliary cirrhosis, overlap syndromes, autoimmune sclerosing cholangitis, secondary sclerosing cholangitis, Focus is also on familial cholestasis, allagile syndrome and other hereditary causes of cholestasis, Systemic causes of cholestasis, advances in pathogenesis and treatment of pruritus, care of the cholestatic patient, and transplantation for cholestatic diseases . Readers will come away with a full overview of the diagnosis and treatment of cholestatic liver diseases.

Author: Steven L. Flamm
Publisher: Elsevier Health Sciences
ISBN: 0323710697
Category : Medical
Languages : en
Pages : 233

View

Book Description
In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Steven Flamm has put together another great update for the hepatology consult. Articles are submitted by expert author and in the format of the clinical review article, provide timely data for diagnosis and treatment. Specific areas addressed include the following: Management of esophageal and gastric varices; Severe thrombocytopenia in chronic liver disease and new management approaches; Pathology in chronic liver disease; Alpha 1 antitrypsin disease and chronic liver disease in adults; Evaluation of management of Budd-Chiari; HBV reactivation with immunosuppressive therapy; Homeopathic products and hepatotoxicity; New uses of TIPS; Dermatologic manifestations of chronic liver disease; Acute on chronic liver failure; Cholangiocarcinoma; Diagnosis and management of hepatic adenoma and focal nodular hyperplasia; Emerging data about the microbiome in chronic liver disease; and Acute viral hepatitis aside from HAV, HBV, and HCV. Readers will come away with the information they need to improve patient outcomes.

Author: E. Jenny Heathcote
Publisher: Saunders
ISBN: 9781416062271
Category : Bile ducts
Languages : en
Pages : 0

View

Book Description
Primary biliary cirrhosis (PBC) is a disease characterized by inflammatory destruction of the small bile ducts within the liver. PBC eventually leads to cirrhosis of the liver. The cause of PBC is unknown, but because of the presence of autoantibodies, it is generally thought to be an autoimmune disease. Other causes, such as infectious agents, have not been completely excluded. In this issue, the guest editor has expert authors present information on important topics such as epidemiology of PBC, pathogenesis of PBC, medical therapies, and liver transplantation in PBC.

Author: Edward L. Krawitt
Publisher: Elsevier Science Health Science Division
ISBN: 9780444828033
Category : Medical
Languages : en
Pages : 656

View

Book Description
The second edition, which appears seven years after the first, is a more comprehensive text and addresses the many recent advances in basic and clinical science applicable to autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, and autoimmune aspects of viral-, drug- and alcohol-induced liver disease and hepatocellular cancer. Pathogenesis, diagnosis and treatment are discussed in depth in light of current understanding of the molecular mechanisms of autoimmunity as it applies to liver disease.

Author: Lawrence Samuel Friedman
Publisher:
ISBN: 9780443066337
Category : Medical
Languages : en
Pages : 481

View

Book Description
Here's instant access to the symptoms, signs, differential diagnosis, and treatment for the full range of liver disorders. Written by an international 'who's who' of hepatology-and now in full color-this new 2nd Edition provides readers with top-notch, authoritative guidance they can count on! Discusses the hottest topics in the field, such as non-alcoholic steatohepatitis (NASH) and the latest information on liver transplantation. Includes expanded coverage of chronic hepatitis C, most notably the use of combination therapy with peginterferon and ribavirin and improvements in the management of the side effects of antiviral therapy. Offers the most recent therapeutic options for the management of chronic hepatitis B and advances in the understanding of the molecular biology of this virus. Updates the approach to the diagnosis of many liver diseases due to newer tests based on molecular techniques and advances in imaging. Features over 340 full-color illustrations. Uses a redesigned templated, outline format that makes reference a snap. Presents a concise, in-depth clinical summary-in an outline format-of the current practice of hepatology for each major disease entity. Provides a liberal use of tables, algorithms, and figures, rendering complex concepts understandable. Includes key point boxes at the beginning of each chapter, providing at-a-glance access to vital information. Includes alert symbols that highlight information that's critical to patient safety.