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Development of Novel Vaccines

Development of Novel Vaccines PDF Author: Alexander von Gabain
Publisher: Springer Science & Business Media
ISBN: 3709107091
Category : Medical
Languages : en
Pages : 318

Book Description
“Development of novel vaccines” gives an overview of the tasks in basic research leading to the final product – the vaccine and its applications, belonging to the most complex biologics in the pharmaceutical field. Distinct from most textbooks in the vaccine arena, the current issue focuses on the translational aspect, namely, how research results can be transformed into life-saving medical interventions. Each chapter of the book deals with one important paradigm for the development of novel vaccines, along the value chain towards the final vaccine, and furthermore, with the inevitable tools required for this process. Contributions are prepared by teams of scientists, all of whom are experts in the field, most of them anchored in biomedical organizations devoted to translational culture, thereby lighting the certain topics from different views. This volume is a must read for researchers engaged in vaccine development and who really want to see their research results to become a product.

Development of Novel Vaccines

Development of Novel Vaccines PDF Author: Alexander von Gabain
Publisher: Springer Science & Business Media
ISBN: 3709107091
Category : Medical
Languages : en
Pages : 318

Book Description
“Development of novel vaccines” gives an overview of the tasks in basic research leading to the final product – the vaccine and its applications, belonging to the most complex biologics in the pharmaceutical field. Distinct from most textbooks in the vaccine arena, the current issue focuses on the translational aspect, namely, how research results can be transformed into life-saving medical interventions. Each chapter of the book deals with one important paradigm for the development of novel vaccines, along the value chain towards the final vaccine, and furthermore, with the inevitable tools required for this process. Contributions are prepared by teams of scientists, all of whom are experts in the field, most of them anchored in biomedical organizations devoted to translational culture, thereby lighting the certain topics from different views. This volume is a must read for researchers engaged in vaccine development and who really want to see their research results to become a product.

Highlights of Progress in Research on Cancer

Highlights of Progress in Research on Cancer PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 60

Book Description


The Effects of Taxation on Capital Accumulation

The Effects of Taxation on Capital Accumulation PDF Author: Martin Feldstein
Publisher: Chicago : University of Chicago Press
ISBN:
Category : Business & Economics
Languages : en
Pages : 512

Book Description
Research on capital formation has long been a major focus of studies sponsored by the National Bureau of Economic Research because of the crucial role of capital accumulation in the process of economic growth. The papers in this volume examine the influence of taxes on capital formation, with specific focus on the determinants of saving and the process of investment in plant and equipment.

Handbook of Meningococcal Disease

Handbook of Meningococcal Disease PDF Author: Matthias Frosch
Publisher: John Wiley & Sons
ISBN: 3527614451
Category : Medical
Languages : en
Pages : 592

Book Description
A comprehensive overview of recent advances, from current basic research and epidemiology, to novel therapeutic strategies and clinical management. Here, the leading scientists who have made major advances in the field provide up-to-date reviews and describe their current knowledge and concepts. As such, this is the first volume to summarize the implications of the meningococcus genome-sequencing project, emphasizing the novel strategies in vaccine development. Following a look at the history, the authors go on to treat the epidemiology of meningococcal disease, as well as the genetics, structure and function of virulence factors. Further chapters cover cross-talk between meningococci and host cells, genomics and immunobiology. The result is a standard handbook for all scientists working in the field. While aimed at advanced specialists in basic research, epidemiologists, public health workers, vaccine developers and clinicians, the book is equally appropriate as introductory reading for graduates embarking on their career in this field.

Human Vaccines

Human Vaccines PDF Author: Kayvon Modjarrad
Publisher: Academic Press
ISBN: 0128025425
Category : Medical
Languages : en
Pages : 211

Book Description
Human Vaccines: Emerging Technologies in Design and Development discusses the advances in molecular biology, biophysics, and informatics—among other disciplines—that have provided scientists with the tools to create new vaccines against emerging and re-emerging pathogens. For example, the virus-like particle technologies that led to licensing of highly efficacious HPV vaccines have only come into full realization in the last 10 years. Their success has, in turn, accelerated the pace with which nanoparticle vaccines are being developed Given the rapidity with which the field is changing and the absence of any text documenting this change, there is a need for a resource that surveys these new vaccine technologies, assesses their potential, and describes their applications. This book provides that resource and complements traditional vaccinology books, but also serves as an excellent standalone for researchers and students with basic knowledge in immunology. - Introduces new topics in vaccine immunology in the context vaccine design and production - Consolidates the growing body of knowledge on new vaccine technologies that have only emerged in the past 2 – 3 decades - Reviews the currently licensed vaccines that have utilized leading-edge technologies and how this has translated into improved efficacy and safety - Provides a broad overview of innovative vaccine technologies, including immunological aspects

Winning Independence

Winning Independence PDF Author: John Ferling
Publisher: Bloomsbury Publishing USA
ISBN: 1635572770
Category : History
Languages : en
Pages : 753

Book Description
Co-Winner of the 2022 Harry M. Ward Book Prize From celebrated historian John Ferling, the underexplored history of the second half of the Revolutionary War, when, after years of fighting, American independence often seemed beyond reach. It was 1778, and the recent American victory at Saratoga had netted the U.S a powerful ally in France. Many, including General George Washington, presumed France's entrance into the war meant independence was just around the corner. Meanwhile, having lost an entire army at Saratoga, Great Britain pivoted to a “southern strategy.” The army would henceforth seek to regain its southern colonies, Virginia, North Carolina, South Carolina, and Georgia, a highly profitable segment of its pre-war American empire. Deep into 1780 Britain's new approach seemed headed for success as the U.S. economy collapsed and morale on the home front waned. By early 1781, Washington, and others, feared that France would drop out of the war if the Allies failed to score a decisive victory that year. Sir Henry Clinton, commander of Britain's army, thought “the rebellion is near its end.” Washington, who had been so optimistic in 1778, despaired: “I have almost ceased to hope.” Winning Independence is the dramatic story of how and why Great Britain-so close to regaining several southern colonies and rendering the postwar United States a fatally weak nation ultimately failed to win the war. The book explores the choices and decisions made by Clinton and Washington, and others, that ultimately led the French and American allies to clinch the pivotal victory at Yorktown that at long last secured American independence.

Vaccine Design

Vaccine Design PDF Author: Sunil Thomas
Publisher:
ISBN: 9781493933877
Category : Vaccines
Languages : en
Pages : 873

Book Description


Immunophenotyping

Immunophenotyping PDF Author: J Philip McCoy Jr
Publisher: Humana
ISBN: 9781493996490
Category : Medical
Languages : en
Pages : 375

Book Description
This volume presents the latest collection of immunophenotypic techniques and applications used in research and clinical settings. Chapters in this book cover topics such as constructions of high dimensions fluorescence and mass cytometry panels; fluorescence barcoding; using dried or lyophilized reagents; and immunophenotypic examples of specific cell types. The book concludes with a discussion on the critical roles of quality control and immunophenotyping in the clinical environment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Immunophenotyping: Methods and Protocols is a valuable resource for any researchers, clinician, or scientist interested in learning more about this evolving field.

Young Guns

Young Guns PDF Author: Eric Cantor
Publisher: Simon and Schuster
ISBN: 1451607350
Category : Political Science
Languages : en
Pages : 186

Book Description
America urgently needs a new direction. But who will provide it? The time has come to move the country forward with a clear agenda based on common sense for the common good. THERE IS A BETTER WAY. Make no mistake: Congressmen Eric Cantor, Paul Ryan, and Kevin McCarthy are proud Republicans. But they believe the party had lost sight of the ideals it believes in, like economic freedom, limited government, the sanctity of life, and putting families first. This isn’t your grandfather’s Republican party. These Young Guns of the House GOP—Cantor (the leader), Ryan (the thinker), and McCarthy (the strategist)—are ready to take their belief in the principles that have made America great and translate it into solutions that will make the future even better, solutions that will create private sector jobs, maximize individual freedom, and establish a better world for our children. This groundbreaking book is a call to action that sets forth a plan for growth, opportunity, and commitment that will propel this country to prosperity once again. Together, the Young Guns are changing the face of the Republican party and giving us a new road map back to the American dream.

A multi-billion-dollar opportunity – Repurposing agricultural support to transform food systems

A multi-billion-dollar opportunity – Repurposing agricultural support to transform food systems PDF Author: Food and Agriculture Organization of the United Nations
Publisher: Food & Agriculture Org.
ISBN: 9251349177
Category : Political Science
Languages : en
Pages : 180

Book Description
Public support mechanisms for agriculture in many cases hinder the transformation towards healthier, more sustainable, equitable, and efficient food systems, thus actively steering us away from meeting the Sustainable Development Goals and targets of the Paris Agreement. This report sets out the compelling case for repurposing harmful agricultural producer support to reverse this situation, by optimizing the use of scarce public resources, strengthening economic recovery from the COVID-19 pandemic, and ultimately driving a food systems transformation that can support global sustainable development commitments. The report provides policymakers with an updated estimate of past and current agricultural producer support for 88 countries, projected up until 2030. The trends emerging from the analysis are a clear call for action at country, regional and global levels to phase out the most distortive, environmentally and socially harmful support, such as price incentives and coupled subsidies, and redirecting it towards investments in public goods and services for agriculture, such as research and development and infrastructure, as well as decoupled fiscal subsidies. Overall, the analysis highlights that, while removing and/or reducing harmful agricultural support is necessary, repurposing initiatives that include measures to minimize policy trade-offs will be needed to ensure a beneficial outcome overall. The report confirms that, while a few countries have started repurposing and reforming agricultural support, broader, deeper, and faster reforms are needed for food systems transformation. Thus, it provides guidance (in six steps) on how governments can repurpose agricultural producer support – and the reforms this will take.