Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Preserving the Promise PDF full book. Access full book title Preserving the Promise by Scott Dessain. Download full books in PDF and EPUB format.
Author: Scott Dessain Publisher: Academic Press ISBN: 0128092092 Category : Medical Languages : en Pages : 277
Book Description
Preserving the Promise: Improving the Culture of Biotech Investment critically examines why most biotech startups fail, as they emerge from universities into an ecosystem that inhibits rather than encourages innovation. This "Valley of Death" squanders our public investments in medical research and with them, the promise of longer and healthier lives. The authors explicate the Translation Gap faced by early stage biotech companies, the result of problematic technology transfer and investment practices, and provide specific prescriptions for improving translation of important discoveries into safe and effective therapies. In Preserving the Promise, Dessain and Fishman build on their collective experience as company founders, healthcare investor (Fishman) and physician/scientist (Dessain). The book offers a forward-looking, critical analysis of "conventional wisdom" that encumbers commercialization practices. It exposes the self-defeating habits of drug development in the Valley of Death, that waste money and extinguish innovative technologies through distorted financial incentives. - Explains why translation of biotech discovery into medicine succeeds so infrequently that it's been dubbed the Valley of Death - Uncovers specific decision-making strategies that more effectively align incentives, improving clinical and financial outcomes for investors, inventor/entrepreneurs, and patients - Examines the critical, early stages of commercialization, where technology transfer offices and Angels act as gatekeepers to development, and where tension between short-term financial and long-term clinical aspirations sinks important technologies - Deconstructs the forces driving biotech, recasts them in a proven conceptual framework, and offers practical guidance for making the system better
Author: Scott Dessain Publisher: Academic Press ISBN: 0128092092 Category : Medical Languages : en Pages : 277
Book Description
Preserving the Promise: Improving the Culture of Biotech Investment critically examines why most biotech startups fail, as they emerge from universities into an ecosystem that inhibits rather than encourages innovation. This "Valley of Death" squanders our public investments in medical research and with them, the promise of longer and healthier lives. The authors explicate the Translation Gap faced by early stage biotech companies, the result of problematic technology transfer and investment practices, and provide specific prescriptions for improving translation of important discoveries into safe and effective therapies. In Preserving the Promise, Dessain and Fishman build on their collective experience as company founders, healthcare investor (Fishman) and physician/scientist (Dessain). The book offers a forward-looking, critical analysis of "conventional wisdom" that encumbers commercialization practices. It exposes the self-defeating habits of drug development in the Valley of Death, that waste money and extinguish innovative technologies through distorted financial incentives. - Explains why translation of biotech discovery into medicine succeeds so infrequently that it's been dubbed the Valley of Death - Uncovers specific decision-making strategies that more effectively align incentives, improving clinical and financial outcomes for investors, inventor/entrepreneurs, and patients - Examines the critical, early stages of commercialization, where technology transfer offices and Angels act as gatekeepers to development, and where tension between short-term financial and long-term clinical aspirations sinks important technologies - Deconstructs the forces driving biotech, recasts them in a proven conceptual framework, and offers practical guidance for making the system better
Author: Al Checchi Publisher: Open Road Media ISBN: 1453221018 Category : Business & Economics Languages : en Pages : 324
Book Description
Entertaining, fast-paced, instructional, The Change Maker is not only a memoir, but a blueprint for how we can change our own lives, as well as the world around us, by providing personal lessons in the values of strategic thinking and responsible leadership. Through compelling true stories, both humorous and serious, Al Checchi demonstrates that through experience, vision, and courage, one person can make a difference and lead others to move beyond their comfort zones and transform our institutions. Al Checchi, a remarkable change maker, chronicles how his creativity, strategic thinking, and negotiating skills helped transform three major American institutions—Marriott Corporation, Walt Disney, and Northwest Airlines—and led him to challenge the California political establishment as a candidate for governor. Peppered with excerpts from speeches and articles, The Change Maker offers thoughtful perspective on institutional change in America since the 1960s, and scalding commentary on the current state of our public and private institutions, political parties, the emergent political class, and the economic policies and leadership of today’s administration. The Change Maker challenges us to confront the status quo and demand accountability and a restoration of the fiduciary standards that are so vital to reclaiming and maintaining America's position of economic and political leadership. Readers will finish the book feeling revitalized, hopeful, and armed with new ideas on how change can, and always will, occur.
Author: Christopher McKnight Nichols Publisher: Harvard University Press ISBN: 0674061187 Category : History Languages : en Pages : 463
Book Description
Spreading democracy abroad or protecting business at home: this book offers a new look at the history of the contest between isolationalism and internationalism that is as current as the wars in Iraq and Afghanistan and as old as America itself, with profiles of the people, policies, and events that shaped the debate.
Author: The Gardeners and Farmers of Centre Terre Vivante Publisher: Chelsea Green Publishing ISBN: 1933392592 Category : Cooking Languages : en Pages : 226
Book Description
Translation of: Conserves naturelles des quatre saisons.
Author: Rena Kornreich Gelissen Publisher: Beacon Press ISBN: 0807093130 Category : Biography & Autobiography Languages : en Pages : 289
Book Description
An expanded edition of the powerful memoir about two sisters' determination to survive during the Holocaust featuring new and never before revealed information about the first transport of women to Auschwitz In March 1942, Rena Kornreich and 997 other young women were rounded up and forced onto the first Jewish transport of women to Auschwitz. Soon after, Rena was reunited with her sister Danka at the camp, beginning a story of love and courage that would last three years and forty-one days. From smuggling bread for their friends to narrowly escaping the ever-present threats that loomed at every turn, the compelling events in Rena’s Promise remind us that humanity and hope can survive inordinate brutality.
Author: Conor McHugh Publisher: Oxford University Press ISBN: 0198810326 Category : Languages : en Pages : 224
Book Description
Some of our attitudes are fitting, others unfitting. It seems fitting to admire Mandela, but not Idi Amin, and to believe that the Seine flows through Paris, but not that the Thames does. Fitting attitudes get things right. Conor McHugh and Jonathan Way argue that fittingness is the key to understanding the normative domain--the domain of reasons, obligations, and value. They develop and defend a novel 'fittingness first' approach, on which fittingness is a normatively basic property and all other normative properties depend on fittingness. They show how this approach illuminates central questions in ethics and epistemology.
Author: Vannetta Chapman Publisher: Harvest House Publishers ISBN: 0736946136 Category : Fiction Languages : en Pages : 308
Book Description
A Promise for Miriam, the first book in a brand-new romantic series from popular author Vannetta Chapman, introduces the Amish community of Pebble Creek and some of the kind, caring people there. As they face challenges to their community from the English world, they come together to reach out to their non-Amish neighbors while still preserving their cherished Plain ways. Amish schoolteacher Miriam King loves her students. At 26, most women her age are married with children of their own, but she hasn’t yet met anyone who can convince her to give up the Plain school that sits along the banks of Pebble Creek. Then newcomer Gabriel Miller steps into her life, bringing his daughter, an air of mystery, and challenges Miriam has never faced before. Will Gabe be able to let go of the past that haunts him? He thinks he just wants to be left alone, but the loving and warm community he and his daughter have moved to has other plans for him. After a near tragedy is averted, he hesitantly returns offers of help and friendship, and he discovers he can make a difference to the people of Pebble Creek—and maybe find love again.
Author: Russ Shafer-Landau Publisher: Oxford University Press ISBN: 0192865609 Category : Electronic book Languages : en Pages : 303
Book Description
Oxford Studies in Metaethics is the only publication devoted exclusively to original philosophical work in the foundations of ethics. It provides an annual selection of much of the best new scholarship being done in the field. Its broad purview includes work being done at the intersections of ethical theory with metaphysics, epistemology, philosophy of language, and philosophy of mind. The essays included in the series provide an excellent basis for understanding recent developments in the field; those who would like to acquaint themselves with the current state of play in metaethics would do well to start here.
Author: Gail Lee Dubrow Publisher: JHU Press ISBN: 9780801870521 Category : Architecture Languages : en Pages : 476
Book Description
This essay collection draws upon work presented at three national conferences on women and historic preservation held at Bryn Mawr College in 1994, Arizona State University in 1997, and at Mount Vernon College in 2000.
Author: Scott Dessain
Author: Scott Dessain
Author: Al Checchi
Author: Christopher McKnight Nichols
Author: United States. Congress. Senate. Special Committee on Aging
Author: The Gardeners and Farmers of Centre Terre Vivante
Author: Rena Kornreich Gelissen
Author: Conor McHugh
Author: Vannetta Chapman
Author: Russ Shafer-Landau
Author: Gail Lee Dubrow