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Author: Evelyn Regar Publisher: CRC Press ISBN: 9780415383486 Category : Medical Languages : en Pages : 776
Book Description
Given that for centuries, the standard tool to understand diseases in tissues was the microscope and that its major limitation was that only excised tissue could be used, recent technology now permits the examination of diseased tissue in vivo. Optical coherence tomography (OCT) has promising potential when applied to coronary artery disease. OCT has the capability to identify coronary plaque and to distinguish between plaques that are stable and unstable. If the plaques are stable then OCT can direct percutaneous intervention (angioplasty or stenting). Optical coherence tomography is a light-based imaging technology that allows for very high resolution imaging in biological tissues. It has been first applied in ophthalmology, where it soon became the golden standard for the assessment of (epi-) retinal processes. The unique imaging capabilities have raised the interest of researchers and clinicians in the field of cardiovascular disease, since OCT offers unique possibilities to study atherosclerosis pathophysiology in vivo. With over 1.1M Americans having a heart attack this year because of unstable plaque rupture, OCT may have an increasingly important role in the early diagnosis of coronary artery disease. This unique publication offers the reader the basic background to OCT and its role in the diagnosis and management of coronary artery disease. The Handbook of Optical Coherence Tomography in Cardiovascular Research introduces the cardiovascular application of this technology. Clinicians, biologists, engineers and physicist are discussing different aspects of cardiovascular OCT application in a multidisciplinary approach. The handbook offers the readership a concise overview on the current state of the art of vascular OCT imaging and sheds light on a variety of exciting new developments. The physics, technical principles of OCT and its application in a broad spectrum of cardiovascular research areas are summarized by highly recognized specialists. The potential of OCT in peripheral and coronary arteries and in developmental cardiology are described. Each research area is introduced by a clinical expert in the field followed by discussion of different aspects from an engineering, biomedical and clinical perspective. Specifically, the current capabilities for plaque characterization, detection of vulnerable plaque, guidance of interventional procedures, Doppler-assessment, and molecular contrast imaging are being described. The Handbook of Optical Coherence Tomography in Cardiovascular Research targets researchers and clinicians involved in the field of atherosclerosis. The summary of basic physics, engineering solutions, pre-clinical and clinical application covers all relevant aspects and will be a valuable reference source.
Author: Evelyn Regar Publisher: CRC Press ISBN: 9780415383486 Category : Medical Languages : en Pages : 776
Book Description
Given that for centuries, the standard tool to understand diseases in tissues was the microscope and that its major limitation was that only excised tissue could be used, recent technology now permits the examination of diseased tissue in vivo. Optical coherence tomography (OCT) has promising potential when applied to coronary artery disease. OCT has the capability to identify coronary plaque and to distinguish between plaques that are stable and unstable. If the plaques are stable then OCT can direct percutaneous intervention (angioplasty or stenting). Optical coherence tomography is a light-based imaging technology that allows for very high resolution imaging in biological tissues. It has been first applied in ophthalmology, where it soon became the golden standard for the assessment of (epi-) retinal processes. The unique imaging capabilities have raised the interest of researchers and clinicians in the field of cardiovascular disease, since OCT offers unique possibilities to study atherosclerosis pathophysiology in vivo. With over 1.1M Americans having a heart attack this year because of unstable plaque rupture, OCT may have an increasingly important role in the early diagnosis of coronary artery disease. This unique publication offers the reader the basic background to OCT and its role in the diagnosis and management of coronary artery disease. The Handbook of Optical Coherence Tomography in Cardiovascular Research introduces the cardiovascular application of this technology. Clinicians, biologists, engineers and physicist are discussing different aspects of cardiovascular OCT application in a multidisciplinary approach. The handbook offers the readership a concise overview on the current state of the art of vascular OCT imaging and sheds light on a variety of exciting new developments. The physics, technical principles of OCT and its application in a broad spectrum of cardiovascular research areas are summarized by highly recognized specialists. The potential of OCT in peripheral and coronary arteries and in developmental cardiology are described. Each research area is introduced by a clinical expert in the field followed by discussion of different aspects from an engineering, biomedical and clinical perspective. Specifically, the current capabilities for plaque characterization, detection of vulnerable plaque, guidance of interventional procedures, Doppler-assessment, and molecular contrast imaging are being described. The Handbook of Optical Coherence Tomography in Cardiovascular Research targets researchers and clinicians involved in the field of atherosclerosis. The summary of basic physics, engineering solutions, pre-clinical and clinical application covers all relevant aspects and will be a valuable reference source.
Author: R. Garcia-Rojo Publisher: CRC Press ISBN: 1000006735 Category : Technology & Engineering Languages : en Pages : 1512
Book Description
This volume contains the proceedings of the Fifth International Conference on the Micromechanics of Granular Media, Powders and Grains 2005. Powders and Grains is an international scientific conference held every 4 years that brings together engineers and physicists interested in the micromechanics of granular media.The book is a guide to the hotte
Author: Tom Schanz Publisher: Springer Science & Business Media ISBN: 3540698760 Category : Technology & Engineering Languages : en Pages : 229
Book Description
These proceedings are a continuation of the series of International Conferences in Germany entitled "Mechanics of Unsaturated Soils." The primary objective is to discuss and understand unsaturated soil behaviour such that engineered activities are made better with times in terms of judgment and quality. The proceedings contain recent research by leading experts in Mechanics of Unsaturated Soils.
Author: António S. Cardoso Publisher: CRC Press ISBN: 1351003615 Category : Technology & Engineering Languages : en Pages : 1656
Book Description
Numerical Methods in Geotechnical Engineering IX contains 204 technical and scientific papers presented at the 9th European Conference on Numerical Methods in Geotechnical Engineering (NUMGE2018, Porto, Portugal, 25—27 June 2018). The papers cover a wide range of topics in the field of computational geotechnics, providing an overview of recent developments on scientific achievements, innovations and engineering applications related to or employing numerical methods. They deal with subjects from emerging research to engineering practice, and are grouped under the following themes: Constitutive modelling and numerical implementation Finite element, discrete element and other numerical methods. Coupling of diverse methods Reliability and probability analysis Large deformation – large strain analysis Artificial intelligence and neural networks Ground flow, thermal and coupled analysis Earthquake engineering, soil dynamics and soil-structure interactions Rock mechanics Application of numerical methods in the context of the Eurocodes Shallow and deep foundations Slopes and cuts Supported excavations and retaining walls Embankments and dams Tunnels and caverns (and pipelines) Ground improvement and reinforcement Offshore geotechnical engineering Propagation of vibrations Following the objectives of previous eight thematic conferences, (1986 Stuttgart, Germany; 1990 Santander, Spain; 1994 Manchester, United Kingdom; 1998 Udine, Italy; 2002 Paris, France; 2006 Graz, Austria; 2010 Trondheim, Norway; 2014 Delft, The Netherlands), Numerical Methods in Geotechnical Engineering IX updates the state-of-the-art regarding the application of numerical methods in geotechnics, both in a scientific perspective and in what concerns its application for solving practical boundary value problems. The book will be much of interest to engineers, academics and professionals involved or interested in Geotechnical Engineering.
Author: Manuel de Matos Fernandes Publisher: CRC Press ISBN: 0429823193 Category : Technology & Engineering Languages : en Pages : 935
Book Description
NUMGE 2018 is the ninth in a series of conferences on Numerical Methods in Geotechnical Engineering organized by the ERTC7 under the auspices of the International Society for Soil Mechanics and Geotechnical Engineering (ISSMGE). The first conference was held in 1986 in Stuttgart, Germany and the series continued every four years (1990 Santander, Spain; 1994 Manchester, United Kingdom; 1998 Udine, Italy; 2002 Paris, France; 2006 Graz, Austria; 2010 Trondheim, Norway; 2014 Delft, The Netherlands). The conference provides a forum for exchange of ideas and discussion on topics related to numerical modelling in geotechnical engineering. Both senior and young researchers, as well as scientists and engineers from Europe and overseas, are invited to attend this conference to share and exchange their knowledge and experiences. This work is the first volume of NUMGE 2018.
Author: Sinisa Mesarovic Publisher: Springer ISBN: 3319941860 Category : Science Languages : en Pages : 348
Book Description
The book helps to answer the following questions: How far have the understanding and mesoscale modeling advanced in recent decades, what are the key open questions that require further research and what are the mathematical and physical requirements for a mesoscale model intended to provide either insight or a predictive engineering tool? It is addressed to young researchers including doctoral students, postdocs and early career faculty,
Author: Masayuki Hyodo Publisher: CRC Press ISBN: 1351377094 Category : Science Languages : en Pages : 550
Book Description
Microscopic re-examination of geomaterials consisting of aggregates can shed light on macroscopic behaviour, including compressibility, anisotropy, yielding, creep, cyclic liquefaction and shear rupture. As a result of this process of examination, new methods of material characterization emerge, leading to a greater degree of accuracy in the specification of new constitutive models with physically-meaningful parameters. The impetus behind this development is an increasing awareness on sustainability, leading to the more efficient use of recycled materials for geotechnical applications. The characteristics of recycled materials, such as compressibility and self-hardening, may differ significantly from those of natural materials, and it is crucial that evaluation is made from a specifically particulate perspective.
Author: Bruno Andreotti Publisher: Cambridge University Press ISBN: 1107034795 Category : Science Languages : en Pages : 471
Book Description
Provides the state-of-the-art of the physics of granular media for graduate students and researchers in physics, applied mathematics and engineering.
Author: William J. Cook Publisher: Springer Science & Business Media ISBN: 3540767967 Category : Mathematics Languages : en Pages : 565
Book Description
The editors and authors dedicate this book to Bernhard Korte on the occasion of his seventieth birthday. We, the editors, are happy about the overwhelming feedback to our initiative to honor him with this book and with a workshop in Bonn on November 3–7,2008.Althoughthiswouldbeareasontolookback,wewouldratherliketolook forward and see what are the interesting research directions today. This book is written by leading experts in combinatorial optimization. All - pers were carefully reviewed, and eventually twenty-three of the invited papers were accepted for this book. The breadth of topics is typical for the eld: combinatorial optimization builds bridges between areas like combinatorics and graph theory, submodular functions and matroids, network ows and connectivity, approximation algorithms and mat- matical programming, computational geometry and polyhedral combinatorics. All these topics are related, and they are all addressed in this book. Combi- torial optimization is also known for its numerous applications. To limit the scope, however, this book is not primarily about applications, although some are mentioned at various places. Most papers in this volume are surveys that provide an excellent overview of an activeresearcharea,butthisbookalsocontainsmanynewresults.Highlightingmany of the currently most interesting research directions in combinatorial optimization, we hope that this book constitutes a good basis for future research in these areas.
Author: Jacek Tejchman Publisher: Springer Science & Business Media ISBN: 3319003186 Category : Science Languages : en Pages : 503
Book Description
During confined flow of bulk solids in silos some characteristic phenomena can be created, such as: sudden and significant increase of wall stresses, different flow patterns, formation and propagation of wall and interior shear zones, fluctuation of pressures and, strong autogenous dynamic effects. These phenomena have not been described or explained in detail yet. The main intention of the experimental and theoretical research presented in this book is to explain the above mentioned phenomena in granular bulk solids and to describe them with numerical FE models verified by experimental results.
Author: Evelyn Regar
Author: Evelyn Regar
Author: R. Garcia-Rojo
Author: Tom Schanz
Author: António S. Cardoso
Author: Manuel de Matos Fernandes
Author: Sinisa Mesarovic
Author: Masayuki Hyodo
Author: Bruno Andreotti
Author: William J. Cook
Author: Jacek Tejchman