Author: Tariq Aftab
Publisher: Springer Nature
ISBN: 3030589757
Category : Science
Languages : en
Pages : 781
Book Description
Before the concept of history began, humans undoubtedly acquired life benefits by discovering medicinal and aromatic plants (MAPs) that were food and medicine. Today, a variety of available herbs and spices are used and enjoyed throughout the world and continue to promote good health. The international market is also quite welcoming for MAPs and essential oils. The increasing environment and nature conscious buyers encourage producers to produce high quality essential oils. These consumer choices lead to growing preference for organic and herbal based products in the world market. As the benefits of medicinal and aromatic plants are recognized, these plants will have a special role for humans in the future. Until last century, the production of botanicals relies to a large degree on wild-collection. However, the increasing commercial collection, largely unmonitored trade, and habitat loss lead to an incomparably growing pressure on plant populations in the wild. Therefore, medicinal and aromatic plants are of high priority for conservation. Given the above, we bring forth a comprehensive volume, “Medicinal and Aromatic Plants: Healthcare and Industrial Applications”, highlighting the various healthcare, industrial and pharmaceutical applications that are being used on these immensely important MAPs and its future prospects. This collection of chapters from the different areas dealing with MAPs caters to the need of all those who are working or have interest in the above topic.
Medicinal and Aromatic Plants
Author: Tariq Aftab
Publisher: Springer Nature
ISBN: 3030589757
Category : Science
Languages : en
Pages : 781
Book Description
Before the concept of history began, humans undoubtedly acquired life benefits by discovering medicinal and aromatic plants (MAPs) that were food and medicine. Today, a variety of available herbs and spices are used and enjoyed throughout the world and continue to promote good health. The international market is also quite welcoming for MAPs and essential oils. The increasing environment and nature conscious buyers encourage producers to produce high quality essential oils. These consumer choices lead to growing preference for organic and herbal based products in the world market. As the benefits of medicinal and aromatic plants are recognized, these plants will have a special role for humans in the future. Until last century, the production of botanicals relies to a large degree on wild-collection. However, the increasing commercial collection, largely unmonitored trade, and habitat loss lead to an incomparably growing pressure on plant populations in the wild. Therefore, medicinal and aromatic plants are of high priority for conservation. Given the above, we bring forth a comprehensive volume, “Medicinal and Aromatic Plants: Healthcare and Industrial Applications”, highlighting the various healthcare, industrial and pharmaceutical applications that are being used on these immensely important MAPs and its future prospects. This collection of chapters from the different areas dealing with MAPs caters to the need of all those who are working or have interest in the above topic.
Publisher: Springer Nature
ISBN: 3030589757
Category : Science
Languages : en
Pages : 781
Book Description
Before the concept of history began, humans undoubtedly acquired life benefits by discovering medicinal and aromatic plants (MAPs) that were food and medicine. Today, a variety of available herbs and spices are used and enjoyed throughout the world and continue to promote good health. The international market is also quite welcoming for MAPs and essential oils. The increasing environment and nature conscious buyers encourage producers to produce high quality essential oils. These consumer choices lead to growing preference for organic and herbal based products in the world market. As the benefits of medicinal and aromatic plants are recognized, these plants will have a special role for humans in the future. Until last century, the production of botanicals relies to a large degree on wild-collection. However, the increasing commercial collection, largely unmonitored trade, and habitat loss lead to an incomparably growing pressure on plant populations in the wild. Therefore, medicinal and aromatic plants are of high priority for conservation. Given the above, we bring forth a comprehensive volume, “Medicinal and Aromatic Plants: Healthcare and Industrial Applications”, highlighting the various healthcare, industrial and pharmaceutical applications that are being used on these immensely important MAPs and its future prospects. This collection of chapters from the different areas dealing with MAPs caters to the need of all those who are working or have interest in the above topic.
Medicinal Plant Research in Africa
Author: Victor Kuete
Publisher: Newnes
ISBN: 0124059368
Category : Science
Languages : en
Pages : 917
Book Description
The pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes. Many African scholars have distinguished themselves in the fields of organic chemistry, pharmacology, and pharmacognosy and other areas related to the study of plant medicinal plants. However, until now, there is no global standard book on the nature and specificity of chemicals isolated in African medicinal plants, as well as a book bringing together and discussing the main bioactive metabolites of these plants. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential. In light of possible academic use, this book also scans the bulk of African medicinal plants extract having promising pharmacological activities. - The book contains data of biologically active plants of Africa, plant occurring compounds and synthesis pathways of secondary metabolites - This book explores the essence of natural substances from African medicinal plants and their pharmacological potential - The authors are world reknowned African Scientists
Publisher: Newnes
ISBN: 0124059368
Category : Science
Languages : en
Pages : 917
Book Description
The pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes. Many African scholars have distinguished themselves in the fields of organic chemistry, pharmacology, and pharmacognosy and other areas related to the study of plant medicinal plants. However, until now, there is no global standard book on the nature and specificity of chemicals isolated in African medicinal plants, as well as a book bringing together and discussing the main bioactive metabolites of these plants. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential. In light of possible academic use, this book also scans the bulk of African medicinal plants extract having promising pharmacological activities. - The book contains data of biologically active plants of Africa, plant occurring compounds and synthesis pathways of secondary metabolites - This book explores the essence of natural substances from African medicinal plants and their pharmacological potential - The authors are world reknowned African Scientists
Bioactive Compounds from Natural Sources
Author: Corrado Tringali
Publisher: CRC Press
ISBN: 0203212312
Category : Science
Languages : en
Pages : 704
Book Description
Interest in obtaining biologically active compounds from natural sources has recently spiked due to their low toxicity, complete biodegradability, availability from renewable sources, and in most cases, low cost. Taking an interdisciplinary approach, Bioactive Compounds from Natural Sources: Isolation, Characterization, and Biological Properties covers general methods and main topics in the research field of bioactive natural products. The book describes general screening methods, modern HPLC hyphenated techniques, and NMR methods in the structural elucidation of compounds and devotes individual chapters to specific topics of research. Surveys on compounds displaying important pharmacological activities are presented in chapters devoted to Mexican medicinal plants, anti-tumor drugs of natural origin, cancer chemopreventive flavonoids, and metabolites displaying anti-HIV, antioxidative, antimalarial, and anti-inflammatory activity. The final chapters are devoted to representative examples of research into marine metabolites: immunomodulating marine glycolipids and surveys of bioactive compounds from marine opisthobranchs and Japanese soft corals. With its focus on modern approaches to the isolation of biologically active natural products, this book encourages interdisciplinary work among chemists, pharmacologists, biologists, botanists, and agronomists with an interest in bioactive natural products.
Publisher: CRC Press
ISBN: 0203212312
Category : Science
Languages : en
Pages : 704
Book Description
Interest in obtaining biologically active compounds from natural sources has recently spiked due to their low toxicity, complete biodegradability, availability from renewable sources, and in most cases, low cost. Taking an interdisciplinary approach, Bioactive Compounds from Natural Sources: Isolation, Characterization, and Biological Properties covers general methods and main topics in the research field of bioactive natural products. The book describes general screening methods, modern HPLC hyphenated techniques, and NMR methods in the structural elucidation of compounds and devotes individual chapters to specific topics of research. Surveys on compounds displaying important pharmacological activities are presented in chapters devoted to Mexican medicinal plants, anti-tumor drugs of natural origin, cancer chemopreventive flavonoids, and metabolites displaying anti-HIV, antioxidative, antimalarial, and anti-inflammatory activity. The final chapters are devoted to representative examples of research into marine metabolites: immunomodulating marine glycolipids and surveys of bioactive compounds from marine opisthobranchs and Japanese soft corals. With its focus on modern approaches to the isolation of biologically active natural products, this book encourages interdisciplinary work among chemists, pharmacologists, biologists, botanists, and agronomists with an interest in bioactive natural products.
Natural Products Isolation
Author: Satya D. Sarker
Publisher: Springer Science & Business Media
ISBN: 1592599559
Category : Science
Languages : en
Pages : 518
Book Description
The term “natural products” spans an extremely large and diverse range of chemical compounds derived and isolated from biological sources. Our interest in natural products can be traced back thousands of years for their usefulness to humankind, and this continues to the present day. Compounds and extracts derived from the biosphere have found uses in medicine, agriculture, cosmetics, and food in ancient and modern societies around the world. Therefore, the ability to access natural products, understand their usefulness, and derive applications has been a major driving force in the field of natural product research. The first edition of Natural Products Isolation provided readers for the first time with some practical guidance in the process of extraction and isolation of natural products and was the result of Richard Cannell’s unique vision and tireless efforts. Unfortunately, Richard Cannell died in 1999 soon after completing the first edition. We are indebted to him and hope this new edition pays adequate tribute to his excellent work. The first edition laid down the “ground rules” and established the techniques available at the time. Since its publication in 1998, there have been significant developments in some areas in natural product isolation. To capture these developments, publication of a second edition is long overdue, and we believe it brings the work up to date while still covering many basic techniques known to save time and effort, and capable of results equivalent to those from more recent and expensive techniques.
Publisher: Springer Science & Business Media
ISBN: 1592599559
Category : Science
Languages : en
Pages : 518
Book Description
The term “natural products” spans an extremely large and diverse range of chemical compounds derived and isolated from biological sources. Our interest in natural products can be traced back thousands of years for their usefulness to humankind, and this continues to the present day. Compounds and extracts derived from the biosphere have found uses in medicine, agriculture, cosmetics, and food in ancient and modern societies around the world. Therefore, the ability to access natural products, understand their usefulness, and derive applications has been a major driving force in the field of natural product research. The first edition of Natural Products Isolation provided readers for the first time with some practical guidance in the process of extraction and isolation of natural products and was the result of Richard Cannell’s unique vision and tireless efforts. Unfortunately, Richard Cannell died in 1999 soon after completing the first edition. We are indebted to him and hope this new edition pays adequate tribute to his excellent work. The first edition laid down the “ground rules” and established the techniques available at the time. Since its publication in 1998, there have been significant developments in some areas in natural product isolation. To capture these developments, publication of a second edition is long overdue, and we believe it brings the work up to date while still covering many basic techniques known to save time and effort, and capable of results equivalent to those from more recent and expensive techniques.
Phytochemistry: An in-silico and in-vitro Update
Author: Shashank Kumar
Publisher: Springer
ISBN: 9811369208
Category : Science
Languages : en
Pages : 575
Book Description
Phytochemistry is the branch of science that deals with the study of plant-derived chemicals or compounds, which are also known as phytochemicals or plant-derived secondary metabolites. Plants are known to produce phytochemicals that are essential for their growth and reproduction, as they protect them from insects, pathogens, and herbivores. Some of the major groups of plant-derived secondary metabolites are phenolics, flavonoids, terpenoids, alkaloids, tannin etc. Plant-derived phytochemicals are pharmacologically active and have the potential to cure various human diseases and disorders. Natural plant products have been known for their medicinal properties for untold years, and form the basis of several medicinal systems such as Chinese, Unani, and Ayurvedic Medicine. This book offers an essential introduction to phytochemicals and their synthetic analogues. It discusses various in silico approaches used to identify pharmacologically active phytochemicals and their biological activities, as well as in vitro and in vivo models/assays that have been utilized for the pharmacological profiling of plant-derived products to combat cancer, diabetes, cardiovascular diseases and neurological disorders. The intended audience includes upper-level undergraduate and graduate students; researchers and scientists from the pharmaceutical/food chemistry/nutrition sciences/biochemistry, and clinical biochemistry fields; and medical students. Sharing the latest findings, the book will familiarize these readers with the concepts, chemistry, and tremendous potential of phytochemistry.
Publisher: Springer
ISBN: 9811369208
Category : Science
Languages : en
Pages : 575
Book Description
Phytochemistry is the branch of science that deals with the study of plant-derived chemicals or compounds, which are also known as phytochemicals or plant-derived secondary metabolites. Plants are known to produce phytochemicals that are essential for their growth and reproduction, as they protect them from insects, pathogens, and herbivores. Some of the major groups of plant-derived secondary metabolites are phenolics, flavonoids, terpenoids, alkaloids, tannin etc. Plant-derived phytochemicals are pharmacologically active and have the potential to cure various human diseases and disorders. Natural plant products have been known for their medicinal properties for untold years, and form the basis of several medicinal systems such as Chinese, Unani, and Ayurvedic Medicine. This book offers an essential introduction to phytochemicals and their synthetic analogues. It discusses various in silico approaches used to identify pharmacologically active phytochemicals and their biological activities, as well as in vitro and in vivo models/assays that have been utilized for the pharmacological profiling of plant-derived products to combat cancer, diabetes, cardiovascular diseases and neurological disorders. The intended audience includes upper-level undergraduate and graduate students; researchers and scientists from the pharmaceutical/food chemistry/nutrition sciences/biochemistry, and clinical biochemistry fields; and medical students. Sharing the latest findings, the book will familiarize these readers with the concepts, chemistry, and tremendous potential of phytochemistry.
Metastatic Cancer: Clinical and Biological Perspectives
Author: Rahul Jandial
Publisher: CRC Press
ISBN: 9781587066597
Category : Medical
Languages : en
Pages : 312
Book Description
Most cancer deaths are a result of metastasis. The spread of a primary tumor to colonize neighboring and distant organs is the relentless endgame that defines the neoplastic process. Patients who have been diagnosed with cancer are treated to prevent both the recurrence of the tumor at the site of origin and metastasis that would re-stage them as advanced stage IV cancer. Historically and still with some types of cancer, stage IV is perceived by patients as “terminal.” Fortunately, recent molecular therapies have extended the lives of patients with advanced cancer and reassuringly people living with metastatic disease increasingly visit our clinics. What is the path forward? Given that the consilience of science and medicine is a dynamic art from which therapies arise, it would be misguided to consider any single work adequate at capturing the horizon for research. So with humility we constructed this text as primer for scientists. It begins with a broad introduction to the clinical management of common cancers. This is intended to serve as a foundation for investigators to consider when developing basic science hypotheses. Unquestionably, medical and surgical care of cancer patients reveals biology and dictates how novel therapeutics will ultimately be evaluated in clinical trials. The second section of this text offers provocative and evolving insights that underscore the breadth of science involved in the elucidation of cancer metastasis biology. The text concludes with information that integrates scientific and clinical foundations to highlight translational research. This book serves as a framework for scientists to conceptualize clinical and translational knowledge on the complexity of disease that is metastatic cancer.
Publisher: CRC Press
ISBN: 9781587066597
Category : Medical
Languages : en
Pages : 312
Book Description
Most cancer deaths are a result of metastasis. The spread of a primary tumor to colonize neighboring and distant organs is the relentless endgame that defines the neoplastic process. Patients who have been diagnosed with cancer are treated to prevent both the recurrence of the tumor at the site of origin and metastasis that would re-stage them as advanced stage IV cancer. Historically and still with some types of cancer, stage IV is perceived by patients as “terminal.” Fortunately, recent molecular therapies have extended the lives of patients with advanced cancer and reassuringly people living with metastatic disease increasingly visit our clinics. What is the path forward? Given that the consilience of science and medicine is a dynamic art from which therapies arise, it would be misguided to consider any single work adequate at capturing the horizon for research. So with humility we constructed this text as primer for scientists. It begins with a broad introduction to the clinical management of common cancers. This is intended to serve as a foundation for investigators to consider when developing basic science hypotheses. Unquestionably, medical and surgical care of cancer patients reveals biology and dictates how novel therapeutics will ultimately be evaluated in clinical trials. The second section of this text offers provocative and evolving insights that underscore the breadth of science involved in the elucidation of cancer metastasis biology. The text concludes with information that integrates scientific and clinical foundations to highlight translational research. This book serves as a framework for scientists to conceptualize clinical and translational knowledge on the complexity of disease that is metastatic cancer.
Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases
Author: Goutam Brahmachari
Publisher: Elsevier
ISBN: 0128157240
Category : Science
Languages : en
Pages : 461
Book Description
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases. - Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery - Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases - Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases
Publisher: Elsevier
ISBN: 0128157240
Category : Science
Languages : en
Pages : 461
Book Description
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases. - Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery - Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases - Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases
Hsp90 in Cancer: Beyond the Usual Suspects
Author:
Publisher: Academic Press
ISBN: 0128024836
Category : Medical
Languages : en
Pages : 290
Book Description
Hsp90 in Cancer: Beyond the Usual Suspects, the latest volume in the Advances in Cancer Research series, focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some of the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression. - Focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins - Highlights the rapidly evolving understanding of the fundamental roles of Hsp90 in cancer biology - Discusses the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression
Publisher: Academic Press
ISBN: 0128024836
Category : Medical
Languages : en
Pages : 290
Book Description
Hsp90 in Cancer: Beyond the Usual Suspects, the latest volume in the Advances in Cancer Research series, focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some of the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression. - Focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins - Highlights the rapidly evolving understanding of the fundamental roles of Hsp90 in cancer biology - Discusses the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression
Chemotherapy of Viral Infections
Author: P E. Came
Publisher: Springer Science & Business Media
ISBN: 3642684874
Category : Medical
Languages : en
Pages : 580
Book Description
" . . . the motto for the therapeutics of the future will have to be de sedibus et causis pharmacorum. " P. EHRLICH, 1909 Exciting events in the basic disciplines of virology, immunology, and pharmacology continue to advance the understanding of the pathogenesis and control of virus diseases. At the same time, the rational development of antiviral agents is attracting, to an increasing extent, the interest of workers in other disciplines. Improvements in technology facilitate the definition of potential target sites for antiviral intervention and unmask new viral and host genes. The outcome is a further steady development of new antiviral agents which approach the "magic bullets" first proposed by PAUL EHRLICH. Remarkable advances in protein synthetic methods that yield polypeptides which inhibit active sites of viral proteins have aided substantially in the basic and clinical study of these antiviral agents. In addition, the extremely rapid progression in recombinant DNA techniques, leading to the synthesis of large quantities of gene products, is also increasing our opportunities at a dashing pace. New information and developing technology facilitate research on the mechanism of action, toxicity, pharmacokinetics, and pharmacodynamics of new agents. The list of clinically effective antiviral agents is expanding and the number of potentially useful compounds is growing rapidly. This book is a combined theoretical text and practical manual which, it is hoped, will be of use to all who have an interest in virus diseases, particularly scientists, physicians and graduate students.
Publisher: Springer Science & Business Media
ISBN: 3642684874
Category : Medical
Languages : en
Pages : 580
Book Description
" . . . the motto for the therapeutics of the future will have to be de sedibus et causis pharmacorum. " P. EHRLICH, 1909 Exciting events in the basic disciplines of virology, immunology, and pharmacology continue to advance the understanding of the pathogenesis and control of virus diseases. At the same time, the rational development of antiviral agents is attracting, to an increasing extent, the interest of workers in other disciplines. Improvements in technology facilitate the definition of potential target sites for antiviral intervention and unmask new viral and host genes. The outcome is a further steady development of new antiviral agents which approach the "magic bullets" first proposed by PAUL EHRLICH. Remarkable advances in protein synthetic methods that yield polypeptides which inhibit active sites of viral proteins have aided substantially in the basic and clinical study of these antiviral agents. In addition, the extremely rapid progression in recombinant DNA techniques, leading to the synthesis of large quantities of gene products, is also increasing our opportunities at a dashing pace. New information and developing technology facilitate research on the mechanism of action, toxicity, pharmacokinetics, and pharmacodynamics of new agents. The list of clinically effective antiviral agents is expanding and the number of potentially useful compounds is growing rapidly. This book is a combined theoretical text and practical manual which, it is hoped, will be of use to all who have an interest in virus diseases, particularly scientists, physicians and graduate students.
Naturally Occurring Quinones
Author: R Thomson
Publisher: Elsevier
ISBN: 0323161340
Category : Science
Languages : en
Pages : 745
Book Description
Naturally Occurring Quinones aims to discuss where quinones, a major group of organic compounds that are considered as pigments, can be found in nature. The book also explains its significance in chemistry and other related fields. The text also mentions the different plant and animal origins of these compounds. The book covers the biogenesis and distribution of these organic compounds; their identification and spectra; and the different kinds of quinolones, which include benzoquinones, naphthaquinones, julichromes, and laccaic acids. The text also elaborates on anthracyclinones and their stereochemistry; extended quinolones, including elsinochromes, erythroaphins, xanthoaphins, chrysoaphins, and aphinins; and miscellaneous quinolones, such as royleanones, tanshinones, isotanshinones, and mitomycins. The text is recommended for students and practitioners in the field of chemistry, biochemistry, and biology, especially those who want to further understand quinolones, their importance in nature and different species, and their possible uses.
Publisher: Elsevier
ISBN: 0323161340
Category : Science
Languages : en
Pages : 745
Book Description
Naturally Occurring Quinones aims to discuss where quinones, a major group of organic compounds that are considered as pigments, can be found in nature. The book also explains its significance in chemistry and other related fields. The text also mentions the different plant and animal origins of these compounds. The book covers the biogenesis and distribution of these organic compounds; their identification and spectra; and the different kinds of quinolones, which include benzoquinones, naphthaquinones, julichromes, and laccaic acids. The text also elaborates on anthracyclinones and their stereochemistry; extended quinolones, including elsinochromes, erythroaphins, xanthoaphins, chrysoaphins, and aphinins; and miscellaneous quinolones, such as royleanones, tanshinones, isotanshinones, and mitomycins. The text is recommended for students and practitioners in the field of chemistry, biochemistry, and biology, especially those who want to further understand quinolones, their importance in nature and different species, and their possible uses.