Physiological Variation and Its Genetic Basis PDF Download

Author: Joseph Sidney Weiner
Publisher: Taylor & Francis Group
ISBN:
Category : Science
Languages : en
Pages : 210

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Author: Christian R. Landry
Publisher: Springer Science & Business Media
ISBN: 9400773471
Category : Science
Languages : en
Pages : 358

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Researchers in the field of ecological genomics aim to determine how a genome or a population of genomes interacts with its environment across ecological and evolutionary timescales. Ecological genomics is trans-disciplinary by nature. Ecologists have turned to genomics to be able to elucidate the mechanistic bases of the biodiversity their research tries to understand. Genomicists have turned to ecology in order to better explain the functional cellular and molecular variation they observed in their model organisms. We provide an advanced-level book that covers this recent research and proposes future development for this field. A synthesis of the field of ecological genomics emerges from this volume. Ecological Genomics covers a wide array of organisms (microbes, plants and animals) in order to be able to identify central concepts that motivate and derive from recent investigations in different branches of the tree of life. Ecological Genomics covers 3 fields of research that have most benefited from the recent technological and conceptual developments in the field of ecological genomics: the study of life-history evolution and its impact of genome architectures; the study of the genomic bases of phenotypic plasticity and the study of the genomic bases of adaptation and speciation.

Author: National Research Council
Publisher: National Academies Press
ISBN: 0309165865
Category : Social Science
Languages : en
Pages : 184

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As the population of older Americans grows, it is becoming more racially and ethnically diverse. Differences in health by racial and ethnic status could be increasingly consequential for health policy and programs. Such differences are not simply a matter of education or ability to pay for health care. For instance, Asian Americans and Hispanics appear to be in better health, on a number of indicators, than White Americans, despite, on average, lower socioeconomic status. The reasons are complex, including possible roles for such factors as selective migration, risk behaviors, exposure to various stressors, patient attitudes, and geographic variation in health care. This volume, produced by a multidisciplinary panel, considers such possible explanations for racial and ethnic health differentials within an integrated framework. It provides a concise summary of available research and lays out a research agenda to address the many uncertainties in current knowledge. It recommends, for instance, looking at health differentials across the life course and deciphering the links between factors presumably producing differentials and biopsychosocial mechanisms that lead to impaired health.

Author: National Research Council
Publisher: National Academies Press
ISBN: 0309038405
Category : Science
Languages : en
Pages : 128

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There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Author: Esteban Domingo
Publisher: Academic Press
ISBN: 0128163321
Category : Science
Languages : en
Pages : 428

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Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. - Features current views on key steps in the origin of life and origins of viruses - Includes examples relating ancestral features of viruses with their current adaptive capacity - Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read - Considers quasispecies as a framework to understand virus adaptability and disease processes

Author: Gowher A. Wani
Publisher: Cambridge Scholars Publishing
ISBN: 1527554902
Category : Science
Languages : en
Pages : 139

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The invasion of ecosystems by alien species is a key driver of global environmental change and many invasive plant species attain sufficiently high abundance to alter the structure and function of an ecosystem. This book is the first publication to explain the reasons as to why some alien species undergo a profound shift in their ecological fortune from being minor components of their native ecosystems to becoming devastating dominants of non-native habitats. The book assesses the ecological, morphological, functional and genetic factors that contribute to invasion success. Cutting-edge tools in molecular genetics in the past two decades have opened up additional avenues for ecologists to address such questions and obtain novel insights in the ecology of invasive species. This text also highlights which molecular approaches are especially useful in discriminating between native and non-native populations of invaders that cannot otherwise be differentiated based on morphological traits. Such molecular approaches can yield useful insights with potential implications for biodiversity managers to identify alien invasive species that are likely to become invaders in the near future, thereby prioritizing them accordingly for different management strategies.

Author: Claude Bouchard
Publisher: Human Kinetics
ISBN: 9780873229517
Category : Education
Languages : en
Pages : 416

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Book Description
Genetics of Fitness and Physical Performance is the first comprehensive reference on the role of the genes in influencing individual variation in fitness and performance. This essential compendium reviews the past 25 years of accumulated evidence on the genetic basis of health- and performance-related fitness phenotypes. Focusing on the interests of sport scientists, the authors provide insight into the significance of this research on nearly every aspect of the study of human physical activity. The book presents the biological basis of heredity and explains the concepts and methods of genetic epidemiology and molecular biology that are necessary to understand this specialized field. With the rapid advances in molecular biology and the paradigms of human genetics, exercise scientists face a dynamic and vibrant new field. This book offers readers new opportunities to better understand atherosclerosis, noninsulin dependent diabetes, obesity, and hypertension by searching for single gene effects and identifying susceptibility genes. The authors review the evidence on the role of the genes for human traits as it pertains to the exercise science field. And they explore the scientific, practical, and ethical issues that confront exercise scientists as progress is made in this field. Genetics of Fitness and Physical Performance is vital reading for scholars in the field of exercise and sport science to understand how recent discoveries in genetics might shape their future research.

Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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Author: J.R. Spkatch
Publisher: Elsevier
ISBN: 0323163289
Category : Science
Languages : en
Pages : 615

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The Bacteria: Volume VII: Mechanisms of Adaptation explores the mechanisms of bacterial adaptations and covers topics ranging from bacterial spores, cysts, and stalks to nitrogen fixation, bacterial chemotaxis, bacteriophage growth, and the structure and biosynthesis of bacterial cell walls. The roles of appendages and surface layers in adaptation of bacteria to their environment are also considered, along with cell division in Escherichia coli. This volume is comprised of nine chapters and begins with a discussion on the structure, properties, formation, and regulation of spores, cysts, and stalks in actinomycetes, blue-green bacteria, myxobacteria, Bacillus, Azotobacter, and Caulobacter. The reader is then introduced to the biochemistry, regulation, genetics, and evolution of nitrogen fixing in organisms; the receptors involved in bacterial chemotaxis and the nature of the sensing mechanism; the outer membrane of gram-negative bacteria; and bacterial functions involved in nutrient detection and acquisition. The roles played by organelles and surface layers in the adaptation of bacteria to their environment are also examined. The final chapter deals with the regulation of, and coordination between, the multitude of events involved in cell division in Escherichia coli. This monograph will be a useful resource for microbiologists, bacteriologists, biochemists, and biologists.

Author: Paul Shaw
Publisher: Cambridge University Press
ISBN: 1107435617
Category : Medical
Languages : en
Pages : 434

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The first comprehensive book on the subject, The Genetic Basis of Sleep and Sleep Disorders covers detailed reviews of the general principles of genetics and genetic techniques in the study of sleep and sleep disorders. The book contains sections on the genetics of circadian rhythms, of normal sleep and wake states and of sleep homeostasis. There are also sections discussing the role of genetics in the understanding of insomnias, hypersomnias including narcolepsy, parasomnias and sleep-related movement disorders. The final chapter highlights the use of gene therapy in sleep disorders. Written by genetic experts and sleep specialists from around the world, the book is up to date and geared specifically to the needs of both researchers and clinicians with an interest in sleep medicine. This book will be an invaluable resource for sleep specialists, neurologists, geneticists, psychiatrists and psychologists.