Nucleic Acids PDF Download

Author: Victor A. Bloomfield
Publisher: Sterling Publishing Company
ISBN: 9780935702491
Category : Science
Languages : en
Pages : 854

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Book Description
Providing a comprehensive account of the structures and physical chemistry properties of nucleic acids, with special emphasis on biological function, this text has been organized to meet the needs of those who have only a basic understanding of physical chemistry and molecular biology.

Author: Shih Yi Wang
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 626

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Book Description
Photochemistry and Photobiology of Nucleic Acids, Volume I: Chemistry covers the historical developments in the study of photobiology and photochemistry of nucleic acid components. This volume is divided into 12 chapters that deal with the isolation and characterization of ultraviolet photoproducts of pyrimidines. After briefly covering the concepts of photochemistry of nucleic acids, this volume goes on describing the UV-induced physical and chemical alterations in nucleic acid components, such as pyrimidines, purines, their nucleosides and nucleotides, and related compounds. Significant chap ...

Author: Chad A. Mirkin
Publisher: CRC Press
ISBN: 0429578067
Category : Medical
Languages : en
Pages : 1866

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Book Description
Spherical nucleic acids (SNAs) comprise a nanoparticle core and a densely packed and highly oriented nucleic acid shell, typically DNA or RNA. They have novel architecture-dependent properties that distinguish them from all other forms of nucleic acids and make them useful in materials synthesis, catalysis, diagnostics, therapeutics, and optics/plasmonics. This book covers over two decades of Dr. Mirkin’s research on SNAs and their anisotropic analogues, including synthesis and fundamental properties, and applications in colloidal crystallization, adaptive matter, and nanomedicine, spanning extra- and intracellular diagnostics, gene regulation, and immunomodulation. It is a reprint volume that compiles 101 key papers from high-impact journals in this research area published by the Mirkin Group at Northwestern University, Illinois, USA, within the International Institute for Nanotechnology, and collaborators. Volume 1 provides an overview and a historical framework of engineering matter from DNA-modified constructs and discusses the enabling features of nucleic acid–functionalized nanomaterials. Volume 2 covers design rules for colloidal crystallization, building blocks for crystal engineering, and DNA and RNA as programmable bonds. Volume 3 discusses colloidal crystallization processes and routes to hierarchical assembly, dynamic nanoparticle superlattices, surface-based and template-confined colloidal crystallization, optics and plasmonics with nanoparticle superlattices, and postsynthetic modification and catalysis with nanoparticle superlattices. Volume 4 covers diagnostic modalities, and intracellular therapeutic and diagnostic schemes based upon nucleic acid–functionalized nanomaterials.

Author: N. Kochetkov
Publisher: Springer Science & Business Media
ISBN: 1468429736
Category : Science
Languages : en
Pages : 382

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Book Description
The study of nucleic acids is one of the most rapidly developing fields in modern science. The exceptionally important role of the nucleic acids as a key to the understanding of the nature of life is reflected in the enormous number of published works on the subject, including many outstanding monographs and surveys. The pathways of syn thesis and metabolism of nucleic acid,s and the many and varied biological functions of these biopolymers are examined with the utmost detail in the literature. Nearly as much attention has been paid to the macromolecular chemistry of the nucleic acids: elucidation of the size and shape of their molecules, the study of the physicochemical properties of their solutions, and the appropriate methods to be used in such research. The surveys of the chemistry of nucleic acids which have been published so far deal almost entirely with their synthesis and, in particular, with the synthetic chemistry of monomers (nucleosides and nucleotides) ; less attention has been paid to the synthesis of poly nucleotides. There is yet another highly important aspect of the chemistry of nucleic acids which is still in the formative stage, the study of the reactivity of nucleic acid macromolecules and their components. This can make an important contribution to the deter mination of the structure of these remarkable biopolymers and to the correct understanding of their biological functions.

Author: Fritz Eckstein
Publisher: Springer Science & Business Media
ISBN: 3642833845
Category : Science
Languages : en
Pages : 231

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Book Description
Molecular biology has always been a discipline of rapid development. Despite this, we are presently experiencing a period of unprecedented proliferation of information in nucleic acid studies and molecular biology. These areas are intimately interwoven, so that each influences the other to their mutual benefit. The rapid growth in information leads to ever-increasing specialization, so that it becomes increasingly difficult for a scientist to keep abreast of developments in all the various aspects of the field, although an up-to-date knowledge of the field as a whole is highly desirable. With this background in mind we present the series Nucleic Acids and Molecular Biology. It comprises focused review articles by active researchers who report on the newest developments in their areas of particular interest.

Author: Jules Duchesne
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 248

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Book Description

Author: Wolfram Saenger
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 230

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Book Description
This volume contains a series of essays which describe a range of problems in the field of nucleic-acid interactions, investigated by a variety of techniques. An introductory chapter on DNA-protein interactions in the regulation of gene expression is followed by papers on selected model systems.

Author: F. Korte
Publisher: Elsevier
ISBN: 0323159435
Category : Science
Languages : en
Pages : 240

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Book Description
Methodicum Chimicum, Volume 11: Natural Compounds, Part 1: Nucleic acids, Proteins and Carbohydrates is devoted to the methods of structural determinations and syntheses of natural products. This text contains four chapters that include a short discussion of the principles of well-proved analytic procedures. It primarily describes the chemistry and biochemistry of nucleic acids, proteins, carbohydrates, and lipids. Other general topics covered include the components, chemical synthesis, sequences, primary structure, and classification of these macromolecules. This book is of value to chemists and scientists who works in associated areas, including medicine.

Author: Gerald D Fasman
Publisher: CRC Press
ISBN: 1351080830
Category : Medical
Languages : en
Pages : 656

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Book Description
This volume contains information on the nucleotide composition of bacterial DNA. Eukaryotic protists, etc.; Nearest neighbour frequencies in DNA; repeated and unique sequences in eukaryotes; nucleic acid sequences in bacteriophage, chloroplasts, mitochondria, kinetoplasts, satellites and TRNA. Information on the physical properties of RNA, atomic coordinates of DNA-DNA. Also included in this volume is information on enzymes involved in nucleic acid function.

Author: R.D. Blake
Publisher: University Science Books
ISBN: 9781891389283
Category : Science
Languages : en
Pages : 812

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Book Description
This new text examines thebiophysics and biochemistry of nucleic acids and proteins, carving outthe dynamic interface between chemistry and molecular biology, and providing adetailed picture of nucleic acids and proteins, their structures, biologicalproperties, and origins and evolution.