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Author: David Mrazek Publisher: Oxford University Press ISBN: 0195367294 Category : Medical Languages : en Pages : 276
Book Description
Psychiatric Pharmacogenomics is a book written to help clinicians to use pharmacogenomic testing to improve the pharmacotherapy that they provide for their patients. It is designed to teach clinicians how to order pharmacogenomic tests and interpret the results. Clinical examples are used to underscore the specific indications for pharmacogenomic testing and to clarify the clinical usefulness of identifying atypical genotypes that result in problematic responses to medication. The first section of the book begins with a basic review of molecular genetics. Additionally, the book also includes an extensive glossary of technical terms associated with molecular genetics and pharmacogenomics. The clinical utility of pharmacogenomic testing is demonstrated throughout the book by describing the implications of genetic variations for the care of individual patients. The second section of the book is organized into fourteen chapters that each focus on the clinical implications of testing for specific genes for which variants have been associated with either therapeutic response or side effects of psychotropic medications. Each of these chapters is structured in the same manner and involves a description of the gene and its significant variants. Each chapter also includes one or more clinical vignettes. The third section of the book discusses the clinical usefulness of pharmacogenomic testing, ethical issues associated with pharmacogenomic testing, and provides predictions for the future development of more sophisticated pharmacogenomic testing.
Author: David Mrazek Publisher: Oxford University Press ISBN: 0195367294 Category : Medical Languages : en Pages : 276
Book Description
Psychiatric Pharmacogenomics is a book written to help clinicians to use pharmacogenomic testing to improve the pharmacotherapy that they provide for their patients. It is designed to teach clinicians how to order pharmacogenomic tests and interpret the results. Clinical examples are used to underscore the specific indications for pharmacogenomic testing and to clarify the clinical usefulness of identifying atypical genotypes that result in problematic responses to medication. The first section of the book begins with a basic review of molecular genetics. Additionally, the book also includes an extensive glossary of technical terms associated with molecular genetics and pharmacogenomics. The clinical utility of pharmacogenomic testing is demonstrated throughout the book by describing the implications of genetic variations for the care of individual patients. The second section of the book is organized into fourteen chapters that each focus on the clinical implications of testing for specific genes for which variants have been associated with either therapeutic response or side effects of psychotropic medications. Each of these chapters is structured in the same manner and involves a description of the gene and its significant variants. Each chapter also includes one or more clinical vignettes. The third section of the book discusses the clinical usefulness of pharmacogenomic testing, ethical issues associated with pharmacogenomic testing, and provides predictions for the future development of more sophisticated pharmacogenomic testing.
Author: Weimin Cai Publisher: Springer ISBN: 9789811538971 Category : Medical Languages : en Pages : 289
Book Description
This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.
Author: Chris Aiken Publisher: ISBN: 9781732952263 Category : Medical Languages : en Pages : 226
Book Description
Prescribing Psychotropics bridges the gap between the complexities of drug pharmacokinetics and everyday clinical practice, providing clinicians more insight into how psychiatric drugs behave (or misbehave!) once their patients take them. The book also includes a series of unusually practical charts and tables that prescribers will find invaluable as they make medication decisions. What you'll find inside: The basics of drug metabolism What you really need to know about drug interactions Food and drink effects on medications Recreational drug interactions Gender and drug metabolism Drug metabolism and ethnicity More than 70 quick-reference tables, charts, and figures
Author: Kalyna Z. Bezchlibnyk-Butler Publisher: Hogrefe & Huber Publishing ISBN: Category : Medical Languages : en Pages : 76
Book Description
Includes bibliography, glossary, and an extensive index which cross-references generic and trade names. New editions are available on a subscription basis.
Author: Bernard Lerer Publisher: Cambridge University Press ISBN: 9781139433822 Category : Medical Languages : en Pages : 470
Book Description
Pharmacogenetics and pharmacogenomics are areas of significant importance at the interface of molecular genetics and psychopharmacology, with implications for drug development and clinical practice. This 2002 book provides a conceptual framework for understanding and studying the pharmacogenetics of psychotropic drugs, reviews advances in the field, and describes the established findings. Coverage extends to antipsychotics, antidepressants, mood stabilising, cognitive-enhancing and anxiolytic drugs. Chapters also examine the interface of pharmacogenetics with substance dependence and brain imaging, and consider its impact on the biotechnology and pharmaceutical industries. This book defines the young field of pharmacogenetics as it applies to psychotropic drugs, and is therefore of interest to all clinicians and researchers working in this field.
Author: Yui-Wing Francis Lam Publisher: Academic Press ISBN: 0123983037 Category : Science Languages : en Pages : 515
Book Description
Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward. Clinical pearls and case studies are used to illustrate real-life experiences and both successful and unsuccessful applications. Tables, figures, and annotations are included throughout the book to facilitate understanding and further reference. - Multi-contributed book and chapters are written by contributors who are experts in their field - Provides perspectives from those involved in all aspects of pharmacogenomics—including academic, regulatory, economic, industry and medical—to illustrate how all of the pieces fit together and where the challenges may be - Includes case studies of both successful and unsuccessful applications so readers can consider the potential and challenges in moving the science into drug development and direct therapeutic applications - Chapters contain discussion questions and clinical pearls and enable readers to reflect on how to move pharmacogenomics forward and apply these observations and useful tips to their own work and research
Author: Russ B. Altman Publisher: Cambridge University Press ISBN: 1107377471 Category : Science Languages : en Pages : 283
Book Description
The study of pharmacogenetics and pharmacogenomics focuses on how our genes and complex gene systems influence our response to drugs. Recent progress in clinical therapeutics has led to the discovery of new biomarkers that make it technically easier to identify groups of patients which are more or less likely to respond to individual therapies. The aim is to improve personalised medicine - not simply to prescribe the right medicine, but to deliver the right drug at the right dose at the right time. This textbook brings together leading experts to discuss the latest information on how human genetics impacts drug response phenotypes. It presents not only the basic principles of pharmacogenetics, but also clinically valuable examples that cover a broad range of specialties and therapeutic areas. This textbook is an invaluable introduction to pharmacogenetics and pharmacogenomics for health care professionals, medical students, pharmacy students, graduate students and researchers in the biosciences.
Author: Joseph F. Goldberg Publisher: Cambridge University Press ISBN: 1108450741 Category : Medical Languages : en Pages : 611
Book Description
A practical guide translating clinical trials findings, across major psychiatric disorders, to devise tailored, evidence-based treatments.
Author: Janusz K. Rybakowski Publisher: Springer ISBN: 3319270400 Category : Medical Languages : en Pages : 125
Book Description
Written by global experts, this book provides a modern comprehensive insight into the pharmacogenetics of treatment of major psychoses: schizophrenia, bipolar disorder and depression. The pharmacogenomics of three categories of the most important psychiatric drugs, antipsychotics, antidepressants and mood stabilizers, has been updated and reviewed. Some promising directions and perspectives for future research in pharmacogenetics in major psychoses are indicated. They are, among others, connected with the development of new methods in molecular genetics and with linking pharmacogenetics assessment with biomarkers, including neuroimaging ones. Finally, the attempts to use pharmacogenetics of antipsychotic, antidepressant and mood-stabilizing drugs in practice are presented. New pharmacogenetic tools may greatly contribute to introducing personalized medicine into psychiatric clinical practice.
Author: David Durham Publisher: Bookbaby ISBN: 9781635871388 Category : Medical Languages : en Pages : 0
Book Description
Psychiatric Pharmacogenetics from concepts to cases is a book written by two authors who are highly distinguished leaders in this cutting edge field. The book gives a synopsis of the history of how the science of pharmacogenetics evolved, how this new science can help address the mounting cost of managing adverse drug events, and explains the physiology of pharmacogenetics - the Cytochrome P450 system. This book is unique in that it is the first of its kind to dedicate a chapter on how adopting pharmacogenetic technology in clinical practice can markedly reduce medico-legal risk, and increase quality of care. It also dedicates chapters on the ethics and social impact of this burgeoning technology. Finally, and certainly not least, this book provides fifteen detailed clinical cases selected from clinic and hospital patients. For the busy psychiatric practitioner, this book promises to advance their knowledge and skills by giving them practical information they can employ immediately.
Author: David Mrazek
Author: David Mrazek
Author: Weimin Cai
Author: Chris Aiken
Author: Kalyna Z. Bezchlibnyk-Butler
Author: Bernard Lerer
Author: Yui-Wing Francis Lam
Author: Russ B. Altman
Author: Joseph F. Goldberg
Author: Janusz K. Rybakowski
Author: David Durham